Works matching IS 2160763X AND DT 2017 AND VI 6

Results: 77

Spotlight on Anti‐CGRP Monoclonal Antibodies in Migraine: The Clinical Evidence to Date.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 6, p. 534, doi. 10.1002/cpdd.345

By:

Pellesi, Lanfranco;
Guerzoni, Simona;
Pini, Luigi Alberto

Publication type:

Article

Some Methodologic Considerations in the Assessment of Methods for Predicting Pharmacokinetic Drug‐Drug Interactions.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 6, p. 529, doi. 10.1002/cpdd.373

By:

Noe, Dennis A.

Publication type:

Article

Safety, Tolerability, and Antihypertensive Effect of SER100, an Opiate Receptor‐Like 1 (ORL‐1) Partial Agonist, in Patients With Isolated Systolic Hypertension.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 6, p. 584, doi. 10.1002/cpdd.330

By:

Kantola, Ilkka;
Scheinin, Mika;
Gulbrandsen, Trygve;
Meland, Nils;
Smerud, Knut T.

Publication type:

Article

LY2963016 Insulin Glargine and Insulin Glargine (Lantus) Produce Comparable Pharmacokinetics and Pharmacodynamics at Two Dose Levels.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 6, p. 556, doi. 10.1002/cpdd.392

By:

Zhang, Xin;
Lam, Eric Chen Quin;
Seger, Mary E.;
Coutant, David;
Chua, Laiyi;
Tan, Lai Hock;
Soon, Danny;
Linnebjerg, Helle

Publication type:

Article

Safety, Tolerability, and Pharmacokinetics of Therapeutic and Supratherapeutic Doses of Tramadol Hydrochloride in Healthy Adults: A Randomized, Double‐Blind, Placebo‐Controlled Multiple‐Ascending‐Dose Study.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 6, p. 592, doi. 10.1002/cpdd.378

By:

DeLemos, Byron;
Richards, Henry M.;
Vandenbossche, Joris;
Ariyawansa, Jay;
Natarajan, Jaya;
Alexander, Binu;
Ramakrishna, Tage;
Murtaugh, Thomas;
Stahlberg, Hans‐Jürgen

Publication type:

Article

Evaluation of Potential Drug–Drug Interaction Between Delayed‐Release Dimethyl Fumarate and a Commonly Used Oral Contraceptive (Norgestimate/Ethinyl Estradiol) in Healthy Women.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 6, p. 604, doi. 10.1002/cpdd.377

By:

Zhu, Bing;
Nestorov, Ivan;
Zhao, Guolin;
Meka, Venkata;
Leahy, Mark;
Kam, Jeanelle;
Sheikh, Sarah I.

Publication type:

Article

Absolute Bioavailability and Pharmacokinetic Comparability of Sirukumab Following Subcutaneous Administration by a Prefilled Syringe or an Autoinjector.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 6, p. 570, doi. 10.1002/cpdd.328

By:

Zhuang, Y.;
de Vries, D. E.;
Marciniak, S. J.;
Liu, H.;
Zhou, H.;
Davis, H. M.;
Leon, F.;
Raible, D.;
Xu, Z.

Publication type:

Article

Impact of Acid‐Reducing Agents on the Pharmacokinetics of Palbociclib, a Weak Base With pH‐Dependent Solubility, With Different Food Intake Conditions.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 6, p. 614, doi. 10.1002/cpdd.356

By:

Sun, Wan;
Klamerus, Karen J.;
Yuhas, Lisa M.;
Pawlak, Sylvester;
Plotka, Anna;
O'Gorman, Melissa;
Kirkovsky, Leonid;
Kosa, Maha;
Wang, Diane

Publication type:

Article

A Randomized, Placebo‐ and Positive‐Controlled, Single‐Dose, Crossover Thorough QT/QTc Study Assessing the Effect of Daprodustat on Cardiac Repolarization in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 6, p. 627, doi. 10.1002/cpdd.342

By:

Caltabiano, Stephen;
Collins, Jon;
Serbest, Gul;
Morgan, Lisa;
Smith, Deborah A.;
Ravindranath, Ramiya;
Cobitz, Alexander R.

Publication type:

Article

The Effect of Verapamil, a P‐Glycoprotein Inhibitor, on the Pharmacokinetics of Peficitinib, an Orally Administered, Once‐Daily JAK Inhibitor.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 6, p. 548, doi. 10.1002/cpdd.344

By:

Zhu, Tong;
Howieson, Corrie;
Wojtkowski, Tomasz;
Garg, Jay P.;
Han, David;
Fisniku, Ogert;
Keirns, James

Publication type:

Article

Relative Bioavailability of a Dolutegravir Dispersible Tablet and the Effects of Low‐ and High‐Mineral‐Content Water on the Tablet in Healthy Adults.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 6, p. 577, doi. 10.1002/cpdd.332

By:

Buchanan, Ann M.;
Holton, Michael;
Conn, Ian;
Davies, Mark;
Choukour, Mike;
Wynne, Brian R.

Publication type:

Article

Lornoxicam Immediate‐Release Tablets: Formulation and Bioequivalence Study in Healthy Mediterranean Volunteers Using a Validated LC‐MS/MS Method.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 6, p. 564, doi. 10.1002/cpdd.333

By:

Zaid, Abdel Naser;
Mousa, Ayman;
Jaradat, Nidal;
Bustami, Rana

Publication type:

Article

Issue Information.

Published in:: Clinical Pharmacology in Drug Development, 2017, v. 6, n. 6, p. 525, doi. 10.1002/cpdd.305
Publication type:: Article

Issue Information.

Published in:: Clinical Pharmacology in Drug Development, 2017, v. 6, p. 1, doi. 10.1002/cpdd.384
Publication type:: Article

Clinical Pharmacokinetics & Pharmacodynamics.

Published in:: Clinical Pharmacology in Drug Development, 2017, v. 6, p. 3, doi. 10.1002/cpdd.385
Publication type:: Article

Population Pharmacokinetics of Edoxaban in Japanese Atrial Fibrillation Patients With Severe Renal Impairment.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 5, p. 484, doi. 10.1002/cpdd.329

By:

Shimizu, Takako;
Tachibana, Masaya;
Kimura, Tetsuya;
Kumakura, Tomohiko;
Yoshihara, Kazutaka

Publication type:

Article

A Randomized Phase 1 Study to Assess the Safety and Pharmacokinetics of the Subcutaneously Injected Anti-LIGHT Antibody, SAR252067.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 3, p. 292, doi. 10.1002/cpdd.295

By:

Zhang, Meng;
Perrin, Laurent;
Pardo, Patricia

Publication type:

Article

Theranos Experience Exposes Weaknesses in FDA Regulatory Discretion.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 5, p. 433, doi. 10.1002/cpdd.374

By:

Jotwani, Rohan;
Boumil, Marcia;
Salem, Deeb;
Wetterhahn, Madeline;
Beninger, Paul

Publication type:

Article

Pharmacokinetic and Bioequivalence Studies of a Newly Developed Branded Generic of Candesartan Cilexetil Tablets in Healthy Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 5, p. 492, doi. 10.1002/cpdd.321

By:

Patel, Rajesh;
Palmer, Jonathan L.;
Joshi, Shashidhar;
Di Ció Gimena, Alejandro;
Esquivel, Florencia

Publication type:

Article

Pharmacokinetics and Safety of DW1029M, a Botanical Drug for the Treatment of Diabetic Nephropathy, Following Single Doses in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 5, p. 499, doi. 10.1002/cpdd.343

By:

Kim, Yunjeong;
Jeon, Ji‐Young;
Kim, Eun‐Young;
Lim, Cheol‐Hee;
Jang, Hwan Bong;
Kim, Min‐Gul

Publication type:

Article

Effect of Food Intake on the Pharmacodynamics of Tenapanor: A Phase 1 Study.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 5, p. 457, doi. 10.1002/cpdd.341

By:

Johansson, Susanne A.;
Knutsson, Mikael;
Leonsson‐Zachrisson, Maria;
Rosenbaum, David P.

Publication type:

Article

Effects of Tenapanor on Cytochrome P450-Mediated Drug-Drug Interactions.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 5, p. 466, doi. 10.1002/cpdd.346

By:

Johansson, Susanne;
Rosenbaum, David P.;
Ahlqvist, Marie;
Rollison, Helen;
Knutsson, Mikael;
Stefansson, Bergur;
Elebring, Marie

Publication type:

Article

Issue Information.

Published in:: Clinical Pharmacology in Drug Development, 2017, v. 6, n. 5, p. 429, doi. 10.1002/cpdd.304
Publication type:: Article

Assessment of the Pharmacokinetics, Pharmacodynamics, and Safety of Single Doses of TV-1106, a Long-Acting Growth Hormone, in Healthy Japanese and Caucasian Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 4, p. 331, doi. 10.1002/cpdd.294

By:

Cohen‐Barak, Orit;
Barkay, Hadas;
Rasamoelisolo, Michele;
Butler, Kathleen;
Yamada, Kazumasa;
Bassan, Merav;
Yoon, Esther;
Spiegelstein, Ofer

Publication type:

Article

Effect of Food and Esomeprazole on the Pharmacokinetics of Alectinib, a Highly Selective ALK Inhibitor, in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 4, p. 388, doi. 10.1002/cpdd.296

By:

Morcos, Peter N.;
Guerini, Elena;
Parrott, Neil;
Dall, Georgina;
Blotner, Steven;
Bogman, Katrijn;
Sturm, Carolina;
Balas, Bogdana;
Martin‐Facklam, Meret;
Phipps, Alex

Publication type:

Article

Comparison of the Pharmacokinetics of Ketorolac Tromethamine After Continuous Subcutaneous Infusion and Repeat Intramuscular Bolus Injections in Healthy Adult Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 4, p. 343, doi. 10.1002/cpdd.319

By:

Burdick, Michael;
Mamelok, Richard;
Hurliman, Michele;
Dupuis, Mariève;
Xie, Yuli;
Grenier, Julie;
Sheldon, Curtis;
Gartner, Michael;
Noymer, Peter

Publication type:

Article

Luseogliflozin, an SGLT2 Inhibitor, in Japanese Patients With Mild/Moderate Hepatic Impairment: A Pharmacokinetic Study.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 5, p. 439, doi. 10.1002/cpdd.364

By:

Samukawa, Yoshishige;
Sata, Michio;
Furihata, Kenichi;
Ito, Toshifumi;
Ueda, Naohiko;
Ochiai, Hidekazu;
Sakai, Soichi;
Kumagai, Yuji

Publication type:

Article

Effect of Food Intake on the Pharmacokinetics of a Novel Methylphenidate Extended-Release Oral Suspension for Attention Deficit Hyperactivity Disorder.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 5, p. 476, doi. 10.1002/cpdd.366

By:

Sallee, Floyd R.;
Palumbo, Donna R.;
Abbas, Richat;
Berry, Sally A.;
Puthli, Shivanand P.;
Kathala, Kalyan K.

Publication type:

Article

Bioequivalence Studies of a Reformulated Dutasteride and Tamsulosin Hydrochloride Combination Capsule and a Commercially Available Formulation.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 5, p. 508, doi. 10.1002/cpdd.334

By:

Kurczewski, Renee;
Bowen, Chet;
Collins, David;
Zhu, John;
Serbest, Gulyeter;
Manyak, Michael

Publication type:

Article

Effect of Sustained Elevated Gastric pH Levels on Gefitinib Exposure.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 5, p. 517, doi. 10.1002/cpdd.337

By:

Tang, Weifeng;
Tomkinson, Helen;
Masson, Eric

Publication type:

Article

Analgesic Efficacy of a New Immediate-Release/Extended-Release Formulation of Ibuprofen: Results From Single- and Multiple-Dose Postsurgical Dental Pain Studies.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 3, p. 302, doi. 10.1002/cpdd.297

By:

Christensen, Steven;
Paluch, Ed;
Jayawardena, Shyamalie;
Daniels, Stephen;
Meeves, Suzanne

Publication type:

Article

Preclinical and Healthy Volunteer Studies of Potential Drug-Drug Interactions Between Tenapanor and Phosphate Binders.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 5, p. 448, doi. 10.1002/cpdd.307

By:

Johansson, Susanne;
Leonsson‐Zachrisson, Maria;
Knutsson, Mikael;
Spencer, Andrew G.;
Labonté, Eric D.;
Deshpande, Desiree;
Kohler, Jill;
Kozuka, Kenji;
Charmot, Dominique;
Rosenbaum, David P.

Publication type:

Article

Safety, Tolerability, and Pharmacokinetics of ARC-520 Injection, an RNA Interference-Based Therapeutic for the Treatment of Chronic Hepatitis B Virus Infection, in Healthy Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 4, p. 350, doi. 10.1002/cpdd.318

By:

Schluep, Thomas;
Lickliter, Jason;
Hamilton, James;
Lewis, David L.;
Lai, Ching‐Lung;
Lau, Johnson YN;
Locarnini, Stephen A.;
Gish, Robert G.;
Given, Bruce D.

Publication type:

Article

An Open-Label, Randomized Bioavailability Study of Alternative Methods of Oral Administration of Naloxegol in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 4, p. 420, doi. 10.1002/cpdd.335

By:

Bui, Khanh;
Birmingham, Bruce;
Diva, Ulysses;
Berger, Bruce

Publication type:

Article

Food Effect on Oral Bioavailability: Old and New Questions.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 4, p. 323, doi. 10.1002/cpdd.351

By:

Yan, Jing‐He

Publication type:

Article

Issue Information.

Published in:: Clinical Pharmacology in Drug Development, 2017, v. 6, n. 4, p. 319, doi. 10.1002/cpdd.303
Publication type:: Article

Platelet Aggregation Inhibitory Effects and Pharmacokinetics of Prasugrel Used in Combination With Aspirin in Healthy Japanese Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 4, p. 398, doi. 10.1002/cpdd.308

By:

Umemura, Kazuo;
Ikeda, Yasuhiko;
Matsushima, Nobuko;
Kondo, Kazunao

Publication type:

Article

Phase 1 and Pharmacokinetic Drug-Drug Interaction Study of Metformin, Losartan, and Linagliptin Coadministered With DW1029M in Healthy Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 4, p. 408, doi. 10.1002/cpdd.320

By:

Moon, Seol Ju;
Kim, Sun‐Young;
Lim, Cheol‐Hee;
Jang, Hwan Bong;
Kim, Min‐Gul;
Jeon, Ji‐Young

Publication type:

Article

Evaluation of Pharmacokinetic Interactions Between Lesinurad, a New Selective Urate Reabsorption Inhibitor, and Commonly Used Drugs for Gout Treatment.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 4, p. 377, doi. 10.1002/cpdd.323

By:

Shen, Zancong;
Tieu, Kathy;
Wilson, David;
Bucci, Gail;
Gillen, Michael;
Lee, Caroline;
Kerr, Bradley

Publication type:

Article

Evaluation of Pharmacokinetic Interactions Between Lesinurad, a New Selective Urate Reabsorption Inhibitor, and CYP Enzyme Substrates Sildenafil, Amlodipine, Tolbutamide, and Repaglinide.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 4, p. 363, doi. 10.1002/cpdd.324

By:

Gillen, Michael;
Yang, Chun;
Wilson, David;
Valdez, Shakti;
Lee, Caroline;
Kerr, Bradley;
Shen, Zancong

Publication type:

Article

Clinical Drug-Drug Interactions Through Cytochrome P450 3A (CYP3A) for the Selective ALK Inhibitor Alectinib.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 3, p. 280, doi. 10.1002/cpdd.298

By:

Morcos, Peter N.;
Cleary, Yumi;
Guerini, Elena;
Dall, Georgina;
Bogman, Katrijn;
Petris, Luigi;
Viteri, Santiago;
Bordogna, Walter;
Yu, Li;
Martin‐Facklam, Meret;
Phipps, Alex

Publication type:

Article

Effect of the Wetting Agent Sodium Lauryl Sulfate on the Pharmacokinetics of Alectinib: Results From a Bioequivalence Study in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 3, p. 266, doi. 10.1002/cpdd.299

By:

Morcos, Peter N.;
Parrott, Neil;
Banken, Ludger;
Timpe, Carsten;
Lindenberg, Marc;
Guerini, Elena;
Dall, Georgina;
Bogman, Katrijn;
Sturm, Carolina;
Zeaiter, Ali;
Martin‐Facklam, Meret;
Phipps, Alex

Publication type:

Article

Clinical Experience With Desvenlafaxine in Treatment of Patients With Fibromyalgia Syndrome.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 3, p. 224, doi. 10.1002/cpdd.271

By:

Allen, Rob;
Sharma, Uma;
Barlas, Suna

Publication type:

Article

Relative Bioavailability and Bioequivalence of Brivaracetam 10 mg/mL Oral Solution and 50-mg Film-Coated Tablet.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 3, p. 313, doi. 10.1002/cpdd.275

By:

Otoul, Christian;
Watanabe, Shikiko;
McCabe, Suzanne;
Stockis, Armel

Publication type:

Article

Pharmacokinetic Interactions Between Isavuconazole and the Drug Transporter Substrates Atorvastatin, Digoxin, Metformin, and Methotrexate in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 1, p. 66, doi. 10.1002/cpdd.280

By:

Yamazaki, Takao;
Desai, Amit;
Goldwater, Ronald;
Han, David;
Lasseter, Kenneth C.;
Howieson, Corrie;
Akhtar, Shahzad;
Kowalski, Donna;
Lademacher, Christopher;
Rammelsberg, Diane;
Townsend, Robert

Publication type:

Article

Pharmacokinetic Effects of Isavuconazole Coadministration With the Cytochrome P450 Enzyme Substrates Bupropion, Repaglinide, Caffeine, Dextromethorphan, and Methadone in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 1, p. 54, doi. 10.1002/cpdd.281

By:

Yamazaki, Takao;
Desai, Amit;
Goldwater, Ronald;
Han, David;
Howieson, Corrie;
Akhtar, Shahzad;
Kowalski, Donna;
Lademacher, Christopher;
Pearlman, Helene;
Rammelsberg, Diane;
Townsend, Robert

Publication type:

Article

Perspectives on HCV: Current Therapeutic Regimens and Drug-Drug Interactions.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 2, p. 147, doi. 10.1002/cpdd.338

By:

Chan, Justin;
Chung, Raymond T.

Publication type:

Article

Plasma Pharmacokinetics of Veledimex, a Small-Molecule Activator Ligand for a Proprietary Gene Therapy Promoter System, in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 3, p. 246, doi. 10.1002/cpdd.287

By:

Cai, Hongliang;
Sun, Lei;
Miao, John;
Krishman, Suma;
Lebel, Francois;
Barrett, John A.

Publication type:

Article

Dose-Dependent Effect of Piragliatin, a Glucokinase Activator, on the QT Interval Following Short-Term Multiple Doses in Patients With Type 2 Diabetes Mellitus.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 3, p. 258, doi. 10.1002/cpdd.289

By:

Zhi, Jianguo;
Zhai, Suoping;
Boldrin, Mark

Publication type:

Article

Some Thoughts About the Mean Concentration-Versus-Time Plot.

Published in:

Clinical Pharmacology in Drug Development, 2017, v. 6, n. 3, p. 220, doi. 10.1002/cpdd.353

By:

Fossler, Michael J.

Publication type:

Article