Works matching IS 2160763X AND DT 2016 AND VI 5

Results: 68

Issue Information.

Published in:: Clinical Pharmacology in Drug Development, 2016, v. 5, n. 6, p. 427, doi. 10.1002/cpdd.229
Publication type:: Article

Ascending Single-Dose, Double-Blind, Placebo-Controlled Safety Study of Noribogaine in Opioid-Dependent Patients.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 6, p. 460, doi. 10.1002/cpdd.254

By:

Glue, Paul;
Cape, Gavin;
Tunnicliff, Donna;
Lockhart, Michelle;
Lam, Fred;
Hung, Noelyn;
Hung, C. Tak;
Harland, Sarah;
Devane, Jane;
Crockett, R. S.;
Howes, John;
Darpo, Borje;
Zhou, Meijian;
Weis, Holger;
Friedhoff, Lawrence

Publication type:

Article

Impact of Renal Impairment on the Pharmacokinetics of Apremilast and Metabolite M12.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 6, p. 469, doi. 10.1002/cpdd.256

By:

Liu, Yong;
Zhou, Simon;
Assaf, Mahmoud;
Nissel, Jim;
Palmisano, Maria

Publication type:

Article

The Pharmacokinetics and Pharmacodynamics of Prasugrel and Clopidogrel in Healthy Japanese Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 6, p. 480, doi. 10.1002/cpdd.259

By:

Umemura, Kazuo;
Iwaki, Takayuki

Publication type:

Article

Glycemic Effect and Safety of a Systemic, Partial Glucokinase Activator, PF-04937319, in Patients With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin-A Randomized, Crossover, Active-Controlled Study.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 6, p. 517, doi. 10.1002/cpdd.261

By:

Denney, William S.;
Denham, Douglas S.;
Riggs, Michael R.;
Amin, Neeta B.

Publication type:

Article

Effect of Cabotegravir on Cardiac Repolarization in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 6, p. 509, doi. 10.1002/cpdd.272

By:

Lou, Yu;
Buchanan, Ann M.;
Chen, Shuguang;
Ford, Susan L.;
Gould, Elizabeth;
Margolis, David;
Spreen, William R.;
Patel, Parul

Publication type:

Article

Stereo-Psychopharmacology: The Case of Citalopram and Escitalopram.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 5, p. 331, doi. 10.1002/cpdd.293

By:

Ng, Isaac;
Greenblatt, H. Karl;
Greenblatt, David J.

Publication type:

Article

Effect of Pradigastat, a Diacylglycerol Acyltransferase 1 Inhibitor, on the QTcF Interval in Humans.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 6, p. 450, doi. 10.1002/cpdd.278

By:

Meyers, Charles D.;
Noe, Adele;
Salunke, Atish;
Movva, Aishwarya;
Kulmatycki, Kenneth;
Neelakantham, Srikanth;
Crissey, Anne;
Majumdar, Tapan;
Chen, Jin

Publication type:

Article

Comparison of Capillary and Venous Drug Concentrations After Administration of a Single Dose of Risperidone, Paliperidone, Quetiapine, Olanzapine, or Aripiprazole.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 6, p. 528, doi. 10.1002/cpdd.290

By:

Remmerie, Bart;
Meulder, Marc;
Weiner, Sveta;
Savitz, Adam

Publication type:

Article

Pharmacokinetics and Safety of Defibrotide in Healthy Japanese Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 6, p. 548, doi. 10.1002/cpdd.262

By:

Umemura, Kazuo;
Iwaki, Takayuki;
Kimura, Toshimi;
Ogawa, Chitose;
Fukuda, Takahiro;
Taniguchi, Shuichi;
Horibe, Keizo;
Goto, Hiroaki;
Yoshimura, Kenichi;
Watanabe, Yasutaka;
Nitani, Chika;
Kikuta, Atsushi

Publication type:

Article

Pharmacokinetics of the Novel Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone (BAY 94-8862) in Individuals With Renal Impairment.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 6, p. 488, doi. 10.1002/cpdd.263

By:

Heinig, Roland;
Kimmeskamp‐Kirschbaum, Nina;
Halabi, Atef;
Lentini, Silvia

Publication type:

Article

Electrocardiographic Effects of a Supratherapeutic Dose of Oritavancin.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 6, p. 502, doi. 10.1002/cpdd.268

By:

Mason, Jay W.;
Bellibas, S. Eralp;
Huang, Nuo‐Yu;
Sanabria, Carlos R.;
Darpo, Borje

Publication type:

Article

Pharmacokinetics, Pharmacodynamics, and Safety of ASP015K (Peficitinib), a New Janus Kinase Inhibitor, in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 6, p. 435, doi. 10.1002/cpdd.273

By:

Cao, Ying Jun;
Sawamoto, Taiji;
Valluri, Udaya;
Cho, Kathy;
Lewand, Michaelene;
Swan, Suzanne;
Lasseter, Kenneth;
Matson, Mark;
Holman, John;
Keirns, James;
Zhu, Tong

Publication type:

Article

Pharmacokinetic and Pharmacodynamic Drug Interaction Study of Piragliatin, a Glucokinase Activator, and Glyburide, a Sulfonylurea, in Type 2 Diabetic Patients.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 6, p. 552, doi. 10.1002/cpdd.276

By:

Zhai, S.;
Georgy, A.;
Liang, Z.;
Zhi, J.

Publication type:

Article

Comparison of Capillary and Venous Plasma Drug Concentrations After Repeated Administration of Risperidone, Paliperidone, Quetiapine, Olanzapine, or Aripiprazole.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 6, p. 538, doi. 10.1002/cpdd.291

By:

Remmerie, Bart;
Meulder, Marc;
Ariyawansa, Jay;
Savitz, Adam

Publication type:

Article

Issue Information.

Published in:: Clinical Pharmacology in Drug Development, 2016, v. 5, n. 5, p. 327, doi. 10.1002/cpdd.228
Publication type:: Article

Open-Label, Randomized, 6-Way Crossover, Single-Dose Study to Determine the Pharmacokinetics of Batefenterol (GSK961081) and Fluticasone Furoate When Administered Alone or in Combination.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 5, p. 399, doi. 10.1002/cpdd.274

By:

Ambery, Claire;
Riddell, Kylie;
Daley‐Yates, Peter

Publication type:

Article

Effects of Food Intake on the Pharmacokinetics of Azilsartan Medoxomil and Chlorthalidone Alone and in Fixed-Dose Combination in Healthy Adults.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 5, p. 393, doi. 10.1002/cpdd.249

By:

Dudkowski, Caroline;
Karim, Aziz;
Munsaka, Melvin

Publication type:

Article

Clinical Pharmacology in Drug Development: Five Years in the Books.

Published in:

2016

By:

Greenblatt, David J.

Publication type:

Editorial

Issue Information.

Published in:: Clinical Pharmacology in Drug Development, 2016, v. 5, p. 1, doi. 10.1002/cpdd.306
Publication type:: Article

2016 Annual Meeting of the American College of Clinical Pharmacology, September 25-27, 2016, Bethesda, MD.

Published in:: Clinical Pharmacology in Drug Development, 2016, v. 5, p. 3, doi. 10.1002/cpdd.292
Publication type:: Article

Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of ASP2408, a Potent Selective T-Cell Costimulation Modulator After Single and Multiple Ascending Doses in Healthy Volunteers and RA Patients.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 5, p. 408, doi. 10.1002/cpdd.251

By:

Zhu, Tong;
Keirns, James;
Howieson, Corrie;
Kaibara, Atsunori;
Goldwater, Ronald;
Kivitz, Alan J.;
Chindalore, Vishala;
Cohen, Stanley;
Santos, Vicki;
Akinlade, Bolanle;
Kernstock, Robert;
Delgado‐Herrera, Leticia;
Blahunka, Paul C;
Karrer, Erik E.;
Garg, Jay P.;
Samberg, Nancy;
Zeiher, Bernhardt G.

Publication type:

Article

Effects of Age, Sex, and Obesity on the Single-Dose Pharmacokinetics of Omarigliptin in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 5, p. 374, doi. 10.1002/cpdd.255

By:

Addy, Carol;
Tatosian, Daniel A.;
Glasgow, Xiaoli S.;
III, Isaias Noel Gendrano;
Sisk, Christine McCrary;
Kauh, Eunkyung A.;
Stoch, S. Aubrey;
Wagner, John A.

Publication type:

Article

A Thorough QTc Study Confirms Early Pharmacokinetics/QTc Modeling: A Supratherapeutic Dose of Omarigliptin, a Once-Weekly DPP-4 Inhibitor, Does Not Prolong the QTc Interval.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 5, p. 383, doi. 10.1002/cpdd.260

By:

Tatosian, Daniel A.;
Cardillo Marricco, Nadia;
Glasgow, Xiaoli Shirley;
DeGroot, Bruce;
Dunnington, Katherine;
George, Laura;
Gendrano, Isaias Noel;
Johnson‐Levonas, Amy O.;
Swearingen, Dennis;
Kauh, Eunkyung

Publication type:

Article

In Silico Predictions and In Vivo Results of Drug-Drug Interactions by Ketoconazole and Verapamil on AZD1305, a Combined Ion Channel Blocker and a Sensitive CYP3A4 Substrate.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 5, p. 364, doi. 10.1002/cpdd.250

By:

Johansson, Susanne;
Löfberg, Boel;
Aunes, Maria;
Lunde, Helen;
Frison, Lars;
Edvardsson, Nils;
Cullberg, Marie

Publication type:

Article

A Phase 1 Dose-Escalation Study of ASP2409, a Selective T-Cell Costimulation Inhibitor, in Stable Rheumatoid Arthritis Patients on Methotrexate Therapy.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 4, p. 259, doi. 10.1002/cpdd.237

By:

Zhang, Wenhui;
Kernstock, Robert M.;
Karrer, Erik E.;
Cohen, Stanley B.;
Chindalore, Vishala L.;
Kivitz, Alan J.;
Blahunka, Paul C.;
Delgado‐Herrera, Leticia;
Zeiher, Bernhardt G.;
Samberg, Nancy L.;
Garg, Jay P.

Publication type:

Article

Phase IA Clinical Trial Evaluating the Tolerability, Pharmacokinetics, and Analgesic Efficacy of an Intrathecally Administered Neurotensin A Analogue in Central Neuropathic Pain Following Spinal Cord Injury.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 4, p. 250, doi. 10.1002/cpdd.253

By:

Sang, Christine N.;
Barnabe, Kate J.;
Kern, Steven E.

Publication type:

Article

Single-Dose Pharmacokinetic Study of Tramadol Extended-Release Tablets in Children and Adolescents.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 5, p. 343, doi. 10.1002/cpdd.266

By:

Vandenbossche, Joris;
Peer, Achiel;
Richards, Henry

Publication type:

Article

Evaluation of the Effect of Tofacitinib on the Pharmacokinetics of Oral Contraceptive Steroids in Healthy Female Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 5, p. 336, doi. 10.1002/cpdd.270

By:

Menon, Sujatha;
Riese, Richard;
Wang, Ronnie;
Alvey, Christine W.;
Shi, Haihong;
Petit, Wendy;
Krishnaswami, Sriram

Publication type:

Article

Confirmation of Biosimilarity in a Pharmacokinetic/Pharmacodynamic Study in Healthy Volunteers for an Analytically Highly Similar Pegfilgrastim.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 5, p. 354, doi. 10.1002/cpdd.269

By:

Desai, Kalpna;
Catalano, Tina;
Rai, Gurinder;
Misra, Priya;
Shah, Nirmesh

Publication type:

Article

Issue Information.

Published in:: Clinical Pharmacology in Drug Development, 2016, v. 5, n. 4, p. 241, doi. 10.1002/cpdd.227
Publication type:: Article

Phase 1 Study of Safety, Tolerability, and Pharmacokinetics of PTC299, an Inhibitor of Stress-Regulated Protein Translation.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 4, p. 296, doi. 10.1002/cpdd.240

By:

Weetall, Marla;
Davis, Thomas;
Elfring, Gary;
Northcutt, Valerie;
Cao, Liangxian;
Moon, Young‐Choon;
Riebling, Peter;
Dali, Mandar;
Hirawat, Samit;
Babiak, John;
Colacino, Joseph;
Almstead, Neil;
Spiegel, Robert;
Peltz, Stuart W.

Publication type:

Article

Compelling Relationship of CYP3A Induction to Levels of the Putative Biomarker 4β-Hydroxycholesterol and Changes in Midazolam Exposure.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 4, p. 245, doi. 10.1002/cpdd.265

By:

Mangold, James B.;
Wu, Fan;
Rebello, Sam

Publication type:

Article

A Phase 1, Randomized, Single-Dose Crossover Pharmacokinetic Study to Investigate the Effect of Food Intake on Absorption of Orteronel (TAK-700) in Healthy Male Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 3, p. 188, doi. 10.1002/cpdd.233

By:

Suri, Ajit;
Pham, Theresa;
MacLean, David B.

Publication type:

Article

A First-in-Patient, Multicenter, Double-Blind, 2-Arm, Placebo-Controlled, Randomized Safety and Tolerability Study of a Novel Oral Drug Candidate, CTP-499, in Chronic Kidney Disease.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 4, p. 314, doi. 10.1002/cpdd.241

By:

Sabounjian, LuAnn;
Graham, Philip;
Wu, Lijun;
Braman, Virginia;
Cheng, Changfu;
Liu, Julie;
Shipley, James;
Neutel, Joel;
Dao, Michael

Publication type:

Article

Pharmacokinetics, Safety, and Tolerability of Fevipiprant (QAW039), a Novel CRTh2 Receptor Antagonist: Results From 2 Randomized, Phase 1, Placebo-Controlled Studies in Healthy Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 4, p. 306, doi. 10.1002/cpdd.244

By:

Erpenbeck, Veit J.;
Vets, Eva;
Gheyle, Lien;
Osuntokun, Wande;
Larbig, Michael;
Neelakantham, Srikanth;
Sandham, David;
Dubois, Gerald;
Elbast, Walid;
Goldsmith, Paul;
Weiss, Markus

Publication type:

Article

Absorption, Distribution, and Excretion of the Investigational Agent Orteronel (TAK-700) in Healthy Male Subjects: A Phase 1, Open-Label, Single-Dose Study.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 3, p. 180, doi. 10.1002/cpdd.234

By:

Suri, Ajit;
Pusalkar, Sandeepraj;
Li, Yuexian;
Prakash, Shimoga

Publication type:

Article

A Pharmacokinetic Study Comparing Eslicarbazepine Acetate Administered Orally as a Crushed or Intact Tablet in Healthy Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 4, p. 278, doi. 10.1002/cpdd.242

By:

Sunkaraneni, Soujanya;
Kharidia, Jahnavi;
Schutz, Ralph;
Blum, David;
Cheng, Hailong

Publication type:

Article

Pharmacokinetics of the Long-Acting Basal Insulin LY2605541 in Subjects With Varying Degrees of Renal Function.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 3, p. 216, doi. 10.1002/cpdd.252

By:

Linnebjerg, Helle;
Choi, Siak Leng;
Lam, Eric Chen Quin;
Mace, Kenneth F.;
Hodgson, Teri S.;
Sinha, Vikram P.

Publication type:

Article

Lung Delivery of Indacaterol and Mometasone Furoate Following Inhalation of QMF149 in Healthy Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 4, p. 285, doi. 10.1002/cpdd.245

By:

Vaidya, Soniya S.;
Khindri, Sanjeev;
Maahs, Suzanne;
Machineni, Surendra;
Hara, Hisanori;
Juan, Axel;
Kaiser, Günther

Publication type:

Article

Drug-Drug Interaction of Omeprazole With the HCV Direct-Acting Antiviral Agents Paritaprevir/Ritonavir and Ombitasvir With and Without Dasabuvir.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 4, p. 269, doi. 10.1002/cpdd.246

By:

Polepally, Akshanth R.;
Dutta, Sandeep;
Hu, Beibei;
Podsadecki, Thomas J.;
Awni, Walid M.;
Menon, Rajeev M.

Publication type:

Article

Sex and Food Influence on Intestinal Absorption of Ketoprofen Gastroresistant Formulation.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 3, p. 196, doi. 10.1002/cpdd.208

By:

Magallanes, Laura;
Lorier, Marianela;
Ibarra, Manuel;
Guevara, Natalia;
Vázquez, Marta;
Fagiolino, Pietro

Publication type:

Article

Issue Information.

Published in:: Clinical Pharmacology in Drug Development, 2016, v. 5, n. 3, p. 163, doi. 10.1002/cpdd.226
Publication type:: Article

Effects of Fostamatinib on the Pharmacokinetics of the CYP2C8 Substrate Pioglitazone: Results From In Vitro and Phase 1 Clinical Studies.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 3, p. 170, doi. 10.1002/cpdd.243

By:

Martin, Paul;
Gillen, Michael;
Millson, David;
Oliver, Stuart;
Brealey, Clive;
Surry, Dominic;
Sweeny, David;
Lau, David;
Leese, Philip

Publication type:

Article

Meldonium (Mildronate): A Performance-Enhancing Drug?

Published in:

2016

By:

Greenblatt, H. Karl;
Greenblatt, David J.

Publication type:

Editorial

Investigation of Drug-Drug Interactions Between Ritobegron, a Selective β<sub>3</sub>-Adrenoceptor Agonist, With Probenecid in Healthy Men.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 3, p. 201, doi. 10.1002/cpdd.212

By:

Abe, Yoshikazu;
Nakano, Yuki;
Kanazawa, Toru;
Furihata, Takao;
Endo, Takuro;
Kobayashi, Mamoru

Publication type:

Article

Effect of 3 Single-Dose Regimens of Opicapone on Levodopa Pharmacokinetics, Catechol- O-Methyltransferase Activity and Motor Response in Patients With Parkinson Disease.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 3, p. 232, doi. 10.1002/cpdd.217

By:

Rocha, José‐Francisco;
Ferreira, Joaquim J.;
Falcão, Amílcar;
Santos, Ana;
Pinto, Roberto;
Nunes, Teresa;
Almeida, Luis;
Soares‐da‐Silva, Patrício

Publication type:

Article

Pharmacokinetics, Safety, and Tolerability of Once-Daily Intranasal Fluticasone Furoate and Levocabastine Administered Alone or Simultaneously as fluticasone Furoate/Levocabastine Fixed-Dose Combination.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 3, p. 225, doi. 10.1002/cpdd.218

By:

Allen, Ann;
Murdoch, Robert D.;
Bareille, Philippe;
Burns, Olivia;
Hughes, Stephen;
Gupta, Ashutosh;
Miller, Sam R.

Publication type:

Article

Relative Bioavailability of a Single Dose of Belimumab Administered Subcutaneously by Prefilled Syringe or Autoinjector in Healthy Subjects.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 3, p. 208, doi. 10.1002/cpdd.219

By:

Struemper, Herbert;
Murtaugh, Thomas;
Gilbert, Jane;
Barton, Matthew E.;
Fire, Joseph;
Groark, James;
Fox, Norma Lynn;
Roth, David;
Gordon, David

Publication type:

Article

In Memoriam: David A. Flockhart, 1952-2015.

Published in:

Clinical Pharmacology in Drug Development, 2016, v. 5, n. 2, p. 89, doi. 10.1002/cpdd.258

By:

Greenblatt, David J.;
Abernethy, Darrell R.

Publication type:

Article