Works matching IS 20959907 AND DT 2024 AND VI 9
Results: 343
Nasal vaccination of triple-RBD scaffold protein with flagellin elicits long-term protection against SARS-CoV-2 variants including JN.1.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01822-3
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- Article
Cas13d-mediated gene knockdown in CAR T cells: towards off-the-shelf cancer treatment.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01830-3
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- Article
Induced pluripotent stem cells (iPSCs): molecular mechanisms of induction and applications.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01809-0
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- Article
Bile acid metabolism and signaling in health and disease: molecular mechanisms and therapeutic targets.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01811-6
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- Article
Dysfunction of the adhesion G protein-coupled receptor latrophilin 1 (ADGRL1/LPHN1) increases the risk of obesity.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01810-7
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- Article
Modularization of adhesion G protein-coupled receptor (aGPCR) structure: how alternative splicing regulates synaptogenesis.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01829-w
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- Article
Gene replacement therapy in Bietti crystalline corneoretinal dystrophy: an open-label, single-arm, exploratory trial.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01806-3
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- Article
SRY-Box transcription factor 9 triggers YAP nuclear entry via direct interaction in tumors.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01805-4
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- Article
Efficacy and safety of human umbilical cord-derived mesenchymal stem cells in the treatment of refractory immune thrombocytopenia: a prospective, single arm, phase I trial.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01793-5
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- Article
FGF7 enhances the expression of ACE2 in human islet organoids aggravating SARS-CoV-2 infection.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01790-8
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- Article
PBX/Knotted 1 homeobox-2 (PKNOX2) is a novel regulator of myocardial fibrosis.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01804-5
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- Article
A novel engineered IL-21 receptor arms T-cell receptor-engineered T cells (TCR-T cells) against hepatocellular carcinoma.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01792-6
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- Article
Drug repurposing for cancer therapy.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01808-1
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- Article
Infection with SARS-CoV-2 can cause pancreatic impairment.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01796-2
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- Article
G protein-coupled receptors (GPCRs): advances in structures, mechanisms, and drug discovery.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01803-6
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- Article
The activity and immune dynamics of PD-1 inhibition on high-risk pulmonary ground glass opacity lesions: insights from a single-arm, phase II trial.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01799-z
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- Article
Pandemic punch: SARS-CoV-2 hits pancreas.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, p. 1, doi. 10.1038/s41392-024-01807-2
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- Article
Poly(A)-specific RNase (PARN) generates and regulates miR-125a-5p 3’-isoforms, displaying an altered expression in breast cancer.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, p. 1, doi. 10.1038/s41392-024-01795-3
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- Article
Anti-lymphangiogenesis for boosting drug accumulation in tumors.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, p. 1, doi. 10.1038/s41392-024-01794-4
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- Article
Phase II study of novel orally PI3Kα/δ inhibitor TQ-B3525 in relapsed and/or refractory follicular lymphoma.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01798-0
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- Article
METTL14 downregulation drives S100A4<sup>+</sup> monocyte-derived macrophages via MyD88/NF-κB pathway to promote MAFLD progression.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01797-1
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- Article
The gasdermin family: emerging therapeutic targets in diseases.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, p. 1, doi. 10.1038/s41392-024-01801-8
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- Article
Thiamine-modified metabolic reprogramming of human pluripotent stem cell-derived cardiomyocyte under space microgravity.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, p. 1, doi. 10.1038/s41392-024-01791-7
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- Article
Protein neddylation and its role in health and diseases.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01800-9
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- Article
Circulating tumor cells shielded with extracellular vesicle-derived CD45 evade T cell attack to enable metastasis.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01789-1
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- Article
Progression from ductal carcinoma in situ to invasive breast cancer: molecular features and clinical significance.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01779-3
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- Article
XELOX (capecitabine plus oxaliplatin) plus bevacizumab (anti-VEGF-A antibody) with or without adoptive cell immunotherapy in the treatment of patients with previously untreated metastatic colorectal cancer: a multicenter, open-label, randomized, controlled, phase 3 trial
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01788-2
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- Article
Adeno-associated virus as a delivery vector for gene therapy of human diseases.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01780-w
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- Article
Macrocyclic peptides: up-and-coming weapons to combat antimicrobial resistance.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, p. 1, doi. 10.1038/s41392-024-01813-4
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- Article
Messing with cancer therapy: how the melanoma phenotype predicts checkpoint inhibitor response.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01785-5
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- Article
The two sides of chromosomal instability: drivers and brakes in cancer.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01767-7
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- Article
Rapid development of double-hit mRNA antibody cocktail against orthopoxviruses.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, p. 1, doi. 10.1038/s41392-024-01766-8
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- Article
RNA modifications in cellular metabolism: implications for metabolism-targeted therapy and immunotherapy.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01777-5
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- Article
Rapid development of double-hit mRNA antibody cocktail against orthopoxviruses.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01766-8
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- Article
First-line camrelizumab (a PD-1 inhibitor) plus apatinib (an VEGFR-2 inhibitor) and chemotherapy for advanced gastric cancer (SPACE): a phase 1 study.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01773-9
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- Article
SARS-CoV-2 envelope protein impairs airway epithelial barrier function and exacerbates airway inflammation via increased intracellular Cl<sup>−</sup> concentration.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01753-z
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- Article
Harnessing innate immune pathways for therapeutic advancement in cancer.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01765-9
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- Article
Cholesterol business: life or death by rust.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01802-7
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- Article
Correction: c-Myc-driven glycolysis polarizes functional regulatory B cells that trigger pathogenic inflammatory responses.
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- 2024
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- Correction Notice
TGF-β signaling in health, disease, and therapeutics.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01764-w
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- Article
Cholesterol business: life or death by rust.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, p. 1, doi. 10.1038/s41392-024-01802-7
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- Article
Protein lipidation in health and disease: molecular basis, physiological function and pathological implication.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01759-7
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- Article
Diabetes and pulmonary infection: how hyperglycaemia shapes the immune system.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01784-6
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- Article
Alpha5 nicotine acetylcholine receptor subunit promotes intrahepatic cholangiocarcinoma metastasis.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01761-z
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- Article
Elevated Kallistatin promotes the occurrence and progression of non-alcoholic fatty liver disease.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01781-9
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- Article
Efficacy and safety of PD-1 blockade plus long-course chemoradiotherapy in locally advanced rectal cancer (NECTAR): a multi-center phase 2 study.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01762-y
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- Article
Tet methylcytosine dioxygenase 2 (TET2) deficiency elicits EGFR-TKI (tyrosine kinase inhibitors) resistance in non-small cell lung cancer.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01778-4
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- Article
Ferroptosis in cancer: From molecular mechanisms to therapeutic strategies.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01769-5
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- Article
Targeting carnitine palmitoyl transferase 1A (CPT1A) induces ferroptosis and synergizes with immunotherapy in lung cancer.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01772-w
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- Article
Effects of dietary intervention on human diseases: molecular mechanisms and therapeutic potential.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01771-x
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- Article