Works matching IS 20959907 AND DT 2022 AND VI 7 AND IP 1

Results: 392

Tripterin liposome relieves severe acute respiratory syndrome as a potent COVID-19 treatment.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01283-6

By:

Que, Haiying;
Hong, Weiqi;
Lan, Tianxia;
Zeng, Hao;
Chen, Li;
Wan, Dandan;
Bi, Zhenfei;
Ren, Wenyan;
Luo, Min;
Yang, Jingyun;
He, Cai;
Zhong, Ailing;
Wei, Xiawei

Publication type:

Article

The sirtuin family in health and disease.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01257-8

By:

Wu, Qi-Jun;
Zhang, Tie-Ning;
Chen, Huan-Huan;
Yu, Xue-Fei;
Lv, Jia-Le;
Liu, Yu-Yang;
Liu, Ya-Shu;
Zheng, Gang;
Zhao, Jun-Qi;
Wei, Yi-Fan;
Guo, Jing-Yi;
Liu, Fang-Hua;
Chang, Qing;
Zhang, Yi-Xiao;
Liu, Cai-Gang;
Zhao, Yu-Hong

Publication type:

Article

Correction To: Dietary folate drives methionine metabolism to promote cancer development by stabilizing MAT IIA.

Published in:

2022

By:

Li, Jin-Tao;
Yang, Hai;
Lei, Ming-Zhu;
Zhu, Wei-Ping;
Su, Ying;
Li, Kai-Yue;
Zhu, Wen-Ying;
Wang, Jian;
Zhang, Lei;
Qu, Jia;
Lv, Lei;
Lu, Hao-Jie;
Chen, Zheng-Jun;
Wang, Lu;
Yin, Miao;
Lei, Qun-Ying

Publication type:

Correction Notice

SARS-CoV-2 hijacks cellular kinase CDK2 to promote viral RNA synthesis.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01239-w

By:

Guo, Saisai;
Lei, Xiaobo;
Chang, Yan;
Zhao, Jianyuan;
Wang, Jing;
Dong, Xiaojing;
Liu, Qian;
Zhang, Zixiong;
Wang, Lidan;
Yi, Dongrong;
Ma, Ling;
Li, Quanjie;
Zhang, Yongxin;
Ding, Jiwei;
Liang, Chen;
Li, Xiaoyu;
Guo, Fei;
Wang, Jianwei;
Cen, Shan

Publication type:

Article

Strong attenuation of SARS-CoV-2 Omicron BA.1 and increased replication of the BA.5 subvariant in human cardiomyocytes.

Published in:

2022

By:

Nchioua, Rayhane;
Diofano, Federica;
Noettger, Sabrina;
von Maltitz, Pascal;
Stenger, Steffen;
Zech, Fabian;
Münch, Jan;
Sparrer, Konstantin M. J.;
Just, Steffen;
Kirchhoff, Frank

Publication type:

Letter

Multifaceted functions of STING in human health and disease: from molecular mechanism to targeted strategy.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01252-z

By:

Zhang, Zili;
Zhou, Haifeng;
Ouyang, Xiaohu;
Dong, Yalan;
Sarapultsev, Alexey;
Luo, Shanshan;
Hu, Desheng

Publication type:

Article

An alphavirus replicon particle delivering prefusion-stabilized spike protein provides potent immunoprotection against SARS-CoV-2 Omicron variant.

Published in:

2022

By:

Zhang, Hong-Qing;
Zhang, Ya-Nan;
Zhang, Zhe-Rui;
Chen, Xiao-Ling;
Hu, Yan-Yan;
Shi, Yu-Jia;
Wang, Jing;
Deng, Cheng-lin;
Zhang, Bo;
Li, Xiao-Dan;
Ye, Han-Qing

Publication type:

Letter

Correction: Drp1-dependent remodeling of mitochondrial morphology triggered by EBV-LMP1 increases cisplatin resistance.

Published in:

2022

By:

Xie, Longlong;
Shi, Feng;
Li, Yueshuo;
Li, We;
Yu, Xinfang;
Zhao, Lin;
Zhou, Min;
Hu, Jianmin;
Luo, Xiangjian;
Tang, Min;
Fan, Jia;
Zhou, Jian;
Gao, Qiang;
Wu, Weizhong;
Zhang, Xin;
Liao, Weihua;
Bode, Ann M.;
Cao, Ya

Publication type:

Correction Notice

Analogous comparison unravels heightened antiviral defense and boosted viral infection upon immunosuppression in bat organoids.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01247-w

By:

Liu, Xiaojuan;
Li, Cun;
Wan, Zhixin;
Chiu, Man Chun;
Huang, Jingjing;
Yu, Yifei;
Zhu, Lin;
Cai, Jian-Piao;
Rong, Lei;
Song, You-qiang;
Chu, Hin;
Cai, Zongwei;
Jiang, Shibo;
Yuen, Kwok-yung;
Zhou, Jie

Publication type:

Article

Aging and aging-related diseases: from molecular mechanisms to interventions and treatments.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01251-0

By:

Guo, Jun;
Huang, Xiuqing;
Dou, Lin;
Yan, Mingjing;
Shen, Tao;
Tang, Weiqing;
Li, Jian

Publication type:

Article

Antibody and T cell responses against wild-type and Omicron SARS-CoV-2 after third-dose BNT162b2 in adolescents.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01282-7

By:

Mu, Xiaofeng;
Cohen, Carolyn A.;
Leung, Daniel;
Rosa Duque, Jaime S.;
Cheng, Samuel M. S.;
Chung, Yuet;
Wong, Howard H. W.;
Lee, Amos M. T.;
Li, Wing Yan;
Tam, Issan Y. S.;
Lam, Jennifer H. Y.;
Lee, Derek H. L.;
Chan, Sau Man;
Tsang, Leo C. H.;
Chan, Karl C. K.;
Li, John K. C.;
Luk, Leo L. H.;
Chaothai, Sara;
Kwan, Kelvin K. H.;
Chu, Nym Coco

Publication type:

Article

Multifaceted functions of STING in human health and disease: from molecular mechanism to targeted strategy.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01252-z

By:

Zhang, Zili;
Zhou, Haifeng;
Ouyang, Xiaohu;
Dong, Yalan;
Sarapultsev, Alexey;
Luo, Shanshan;
Hu, Desheng

Publication type:

Article

cBAF and MYC: decision makers for T cell memory differentiation.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01238-x

By:

Ma, Kaili;
Cheng, Hongcheng;
Zhang, Lianjun

Publication type:

Article

Targeting CRL4 suppresses chemoresistant ovarian cancer growth by inducing mitophagy.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01253-y

By:

Meng, Yang;
Qiu, Lei;
Zeng, Xinyi;
Hu, Xiaoyan;
Zhang, Yaguang;
Wan, Xiaowen;
Mao, Xiaobing;
Wu, Jian;
Xu, Yongfeng;
Xiong, Qunli;
Chen, Zhixin;
Zhang, Bo;
Han, Junhong

Publication type:

Article

Identification of a class of potent USP25/28 inhibitors with broad-spectrum anti-cancer activity.

Published in:

2022

By:

Peng, Jin;
Jiang, Kun;
Sun, Xiao;
Wu, Lingzhi;
Wang, Jiewei;
Xi, Xiaomei;
Tan, Xu;
Liang, Tingbo;
Tan, Changheng;
Zhang, Pumin

Publication type:

Letter

Small molecules in the treatment of COVID-19.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01249-8

By:

Lei, Sibei;
Chen, Xiaohua;
Wu, Jieping;
Duan, Xingmei;
Men, Ke

Publication type:

Article

Recent advances in developing active targeting and multi-functional drug delivery systems via bioorthogonal chemistry.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01250-1

By:

Yi, Wenzhe;
Xiao, Ping;
Liu, Xiaochen;
Zhao, Zitong;
Sun, Xiangshi;
Wang, Jue;
Zhou, Lei;
Wang, Guanru;
Cao, Haiqiang;
Wang, Dangge;
Li, Yaping

Publication type:

Article

FFAR4 improves the senescence of tubular epithelial cells by AMPK/SirT3 signaling in acute kidney injury.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01254-x

By:

Yang, Letian;
Wang, Bo;
Guo, Fan;
Huang, Rongshuang;
Liang, Yan;
Li, Lingzhi;
Tao, Sibei;
Yin, Ting;
Fu, Ping;
Ma, Liang

Publication type:

Article

Molecular mechanisms of exercise contributing to tissue regeneration.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01233-2

By:

Chen, Jibao;
Zhou, Ren;
Feng, Ye;
Cheng, Lin

Publication type:

Article

CD147 contributes to SARS-CoV-2-induced pulmonary fibrosis.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01230-5

By:

Wu, Jiao;
Chen, Liang;
Qin, Chuan;
Huo, Fei;
Liang, Xue;
Yang, Xu;
Zhang, Kui;
Lin, Peng;
Liu, Jiangning;
Feng, Zhuan;
Zhou, Jiansheng;
Pei, Zhuo;
Wang, Yatao;
Sun, Xiu-Xuan;
Wang, Ke;
Geng, Jiejie;
Zheng, Zhaohui;
Fu, Xianghui;
Liu, Man;
Wang, Qingyi

Publication type:

Article

Copper homeostasis and cuproptosis in health and disease.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01229-y

By:

Chen, Liyun;
Min, Junxia;
Wang, Fudi

Publication type:

Article

Enhanced replication of SARS-CoV-2 Omicron BA.2 in human forebrain and midbrain organoids.

Published in:

2022

By:

Hou, Yuxin;
Li, Chang;
Yoon, Chaemin;
Leung, On Wah;
You, Sikun;
Cui, Xiaoming;
Chan, Jasper Fuk-Woo;
Pei, Duanqing;
Cheung, Hoi Hung;
Chu, Hin

Publication type:

Letter

Organelle-targeted therapies: a comprehensive review on system design for enabling precision oncology.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01243-0

By:

Yang, Jingjing;
Griffin, Anthony;
Qiang, Zhe;
Ren, Jie

Publication type:

Article

The Hippo signalling pathway and its implications in human health and diseases.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01191-9

By:

Fu, Minyang;
Hu, Yuan;
Lan, Tianxia;
Guan, Kun-Liang;
Luo, Ting;
Luo, Min

Publication type:

Article

The Hippo signalling pathway and its implications in human health and diseases.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01191-9

By:

Fu, Minyang;
Hu, Yuan;
Lan, Tianxia;
Guan, Kun-Liang;
Luo, Ting;
Luo, Min

Publication type:

Article

Epigenetic regulation of aging: implications for interventions of aging and diseases.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01211-8

By:

Wang, Kang;
Liu, Huicong;
Hu, Qinchao;
Wang, Lingna;
Liu, Jiaqing;
Zheng, Zikai;
Zhang, Weiqi;
Ren, Jie;
Zhu, Fangfang;
Liu, Guang-Hui

Publication type:

Article

Monkeypox: epidemiology, pathogenesis, treatment and prevention.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01215-4

By:

Huang, Yong;
Mu, Li;
Wang, Wei

Publication type:

Article

Fire up the pyre: inosine thermogenic signaling for obesity therapy.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01218-1

By:

Willemsen, Nienke;
Kotschi, Stefan;
Bartelt, Alexander

Publication type:

Article

A PD-L1-targeting chimeric switch receptor enhances efficacy of CAR-T cell for pleural and peritoneal metastasis.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01198-2

By:

Ma, Qizhi;
He, Xia;
Zhang, Benxia;
Guo, Fuchun;
Ou, Xuejin;
Yang, Qiyu;
Shu, Pei;
Chen, Yue;
Li, Kai;
Gao, Ge;
Zhu, Yajuan;
Qin, Diyuan;
Tang, Jie;
Li, Xiaoyu;
Jing, Meng;
Zhao, Jian;
Mo, Zeming;
Liu, Ning;
Zeng, Yao;
Zhou, Kexun

Publication type:

Article

Innate immune imprints in SARS-CoV-2 Omicron variant infection convalescents.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01237-y

By:

Li, Zhiqing;
Chen, Xiaosu;
Dan, Junyan;
Hu, Tianju;
Hu, Ye;
Liu, Shuxun;
Chai, Yangyang;
Shi, Yansong;
Wu, Jian;
Ni, Hailai;
Zhu, Jiaqi;
Wu, Yanfeng;
Li, Nan;
Yu, Yizhi;
Wang, Zhongfang;
Zhao, Jincun;
Zhong, Nanshan;
Ren, Xianwen;
Shen, Zhongyang;
Cao, Xuetao

Publication type:

Article

The mechanism underlying extrapulmonary complications of the coronavirus disease 2019 and its therapeutic implication.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-00907-1

By:

Ning, Qin;
Wu, Di;
Wang, Xiaojing;
Xi, Dong;
Chen, Tao;
Chen, Guang;
Wang, Hongwu;
Lu, Huiling;
Wang, Ming;
Zhu, Lin;
Hu, Junjian;
Liu, Tingting;
Ma, Ke;
Han, Meifang;
Luo, Xiaoping

Publication type:

Article

Single-cell transcriptomic profiling unravels the adenoma-initiation role of protein tyrosine kinases during colorectal tumorigenesis.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-00881-8

By:

Zheng, Xiaobo;
Song, Jinen;
Yu, Chune;
Zhou, Zongguang;
Liu, Xiaowei;
Yu, Jing;
Xu, Guangchao;
Yang, Jiqiao;
He, Xiujing;
Bai, Xin;
Luo, Ya;
Bao, Yu;
Li, Huifang;
Yang, Lie;
Xu, Mingqing;
Song, Nan;
Su, Xiaodong;
Xu, Jie;
Ma, Xuelei;
Shi, Hubing

Publication type:

Article

Correction: Lactate metabolism in human health and disease.

Published in:

2022

By:

Li, Xiaolu;
Yang, Yanyan;
Zhang, Bei;
Lin, Xiaotong;
Fu, Xiuxiu;
An, Yi;
Zou, Yulin;
Wang, Jian-Xun;
Wang, Zhibin;
Yu, Tao

Publication type:

Correction Notice

Acetylshikonin inhibits inflammatory responses and Papain-like protease activity in murine model of COVID-19.

Published in:

2022

By:

Lu, Ning;
Gu, Tingxuan;
Tian, Xueli;
Zhao, Simin;
Jin, Guoguo;
Mangaladoss, Fredimoses;
Qiao, Yan;
Liu, Kangdong;
Zhao, Ran;
Dong, Zigang

Publication type:

Letter

Dysregulated ceramides metabolism by fatty acid 2-hydroxylase exposes a metabolic vulnerability to target cancer metastasis.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01199-1

By:

Zhou, Xuantong;
Huang, Furong;
Ma, Gang;
Wei, Wenqing;
Wu, Nan;
Liu, Zhihua

Publication type:

Article

Correction To: Signaling pathways in obesity: mechanisms and therapeutic interventions.

Published in:

2022

By:

Wen, Xue;
Zhang, Bohan;
Wu, Beiyi;
Xiao, Haitao;
Li, Zehua;
Li, Ruoyu;
Xu, Xuewen;
Li, Tao

Publication type:

Correction Notice

S100A7 attenuates immunotherapy by enhancing immunosuppressive tumor microenvironment in lung squamous cell carcinoma.

Published in:

2022

By:

Liu, Chengming;
Zheng, Sufei;
Lu, Zhiliang;
Wang, Zhanyu;
Wang, Sihui;
Feng, Xiaoli;
Wang, Yan;
Sun, Nan;
He, Jie

Publication type:

Letter

FGF21 alleviates microvascular damage following limb ischemia/reperfusion injury by TFEB-mediated autophagy enhancement and anti-oxidative response.

Published in:

2022

By:

Chen, Fanfeng;
Zhan, Jiayu;
Yan, Xiaoqing;
Mamun, Abdullah Al;
Zhang, Yu;
Xu, Yitie;
Zhang, Hongyu;
Li, Xiaokun;
Zhou, Kailiang;
Xiao, Jian

Publication type:

Letter

IKKβ binds NLRP3 providing a shortcut to inflammasome activation for rapid immune responses.

Published in:

2022

By:

Asare, Yaw;
Shnipova, Margarita;
Živković, Luka;
Schlegl, Christina;
Tosato, Federica;
Aronova, Arailym;
Brandhofer, Markus;
Strohm, Laura;
Beaufort, Nathalie;
Malik, Rainer;
Weber, Christian;
Bernhagen, Jürgen;
Dichgans, Martin

Publication type:

Letter

A small molecule inhibitor of the UBE2F-CRL5 axis induces apoptosis and radiosensitization in lung cancer.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01182-w

By:

Xu, Tiantian;
Ma, Qisheng;
Li, Yanan;
Yu, Qing;
Pan, Peichen;
Zheng, Yawen;
Li, Zhijian;
Xiong, Xiufang;
Hou, Tingjun;
Yu, Bin;
Liu, Hongmin;
Sun, Yi

Publication type:

Article

Unexpected little helpers: microbiota stimulate systemic antiviral defenses.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01217-2

By:

Klute, Susanne;
Hoenigsperger, Helene;
Sparrer, Konstantin M. J.

Publication type:

Article

Top(ological-operon) secret behind the long-range transcriptional coupling.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01195-5

By:

Zhang, Lei;
Wu, Zhibing;
Lu, Huasong

Publication type:

Article

Targeting TM4SF1 exhibits therapeutic potential via inhibition of cancer stem cells.

Published in:

2022

By:

Chen, Guang;
She, Xiaofei;
Yin, Yanxin;
Ma, Junxian;
Gao, Yaqun;
Gao, Hua;
Qin, Huanlong;
Fang, Jianmin

Publication type:

Letter

Therapeutic strategy targeting host lipolysis limits infection by SARS-CoV-2 and influenza A virus.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01223-4

By:

Baek, Yeong-Bin;
Kwon, Hyung-Jun;
Sharif, Muhammad;
Lim, Jeongah;
Lee, In-Chul;
Ryu, Young Bae;
Lee, Jae-In;
Kim, Ji-Sun;
Lee, Young-Seung;
Kim, Dong-Hoon;
Park, Sang-Ik;
Kim, Don-Kyu;
Kim, Jeong-Sun;
Choy, Hyon E.;
Lee, Sunwoo;
Choi, Hueng-Sik;
Osborne, Timothy F.;
Jeon, Tae-Il;
Cho, Kyoung-Oh

Publication type:

Article

An mRNA vaccine with broad-spectrum neutralizing protection against Omicron variant sublineages BA.4/5 -included SARS-CoV-2.

Published in:

2022

By:

Sang, Ye;
Zhang, Zhen;
Li, Entao;
Lu, Haitao;
Long, Jinrong;
Cao, Yiming;
Yu, Changxiao;
Wang, Tiecheng;
Yang, Jing;
Wang, Shengqi

Publication type:

Letter

Neoadjuvant PD-1 blockade: a promising nonoperative strategy for mismatch repair–deficient, locally advanced rectal cancer.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01216-3

By:

Mi, Mi;
Ye, Chenyang;
Yuan, Ying

Publication type:

Article

Characteristics and significance of peripheral blood T-cell receptor repertoire features in patients with indeterminate lung nodules.

Published in:

2022

By:

Luo, Huaichao;
Zu, Ruiling;
Huang, Ziru;
Li, Yingqiang;
Liao, Yulin;
Luo, Wenxin;
Zhou, Peng;
Wang, Dongsheng;
Chen, Shifu;
Li, Weimin;
Huang, Jian

Publication type:

Letter

SARS-CoV-2 N protein potentiates host NPM1-snoRNA translation machinery to enhance viral replication.

Published in:

2022

By:

Wang, Hui;
Shi, Danrong;
Jiang, Penglei;
Yu, Zebin;
Han, Yingli;
Zhang, Zhaoru;
Wang, Peihui;
Huang, He;
Yao, Hangping;
Qian, Pengxu

Publication type:

Letter

Targeting metabolic rewiring might decrease spread of tumor cells: Mitochondrial tRNA modifications promote cancer metastasis.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01205-6

By:

Luu, Maik;
Visekruna, Alexander

Publication type:

Article

IL-17 signaling in skin repair: safeguarding metabolic adaptation of wound epithelial cells.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01202-9

By:

Wang, Juan;
Ding, Xiaolei

Publication type:

Article