Works matching IS 20959907 AND DT 2019 AND VI 4 AND IP 1
Results: 64
PROTACs: great opportunities for academia and industry.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. 1, doi. 10.1038/s41392-019-0101-6
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- Article
The β-catenin/YAP signaling axis is a key regulator of melanoma-associated fibroblasts.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. 1, doi. 10.1038/s41392-019-0100-7
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- Article
The emerging treatment landscape of targeted therapy in non-small-cell lung cancer.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. 1, doi. 10.1038/s41392-019-0099-9
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- Article
Targeting epigenetic regulators for cancer therapy: mechanisms and advances in clinical trials.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. 1, doi. 10.1038/s41392-019-0095-0
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- Article
TGIF2 promotes the progression of lung adenocarcinoma by bridging EGFR/RAS/ERK signaling to cancer cell stemness.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. 1, doi. 10.1038/s41392-019-0098-x
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- Article
Structures of BRAF–MEK1–14-3-3 sheds light on drug discovery.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. 1, doi. 10.1038/s41392-019-0096-z
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- Article
Peptides encoded by noncoding genes: challenges and perspectives.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. 1, doi. 10.1038/s41392-019-0092-3
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- Article
Integrative analysis of DNA methylation and gene expression identified cervical cancer-specific diagnostic biomarkers.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. 1, doi. 10.1038/s41392-019-0081-6
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- Article
DNA-PKcs promotes alcohol-related liver disease by activating Drp1-related mitochondrial fission and repressing FUNDC1-required mitophagy.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0094-1
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- Article
MKP-1 reduces Aβ generation and alleviates cognitive impairments in Alzheimer's disease models.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0091-4
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- Article
Dickkopf-1 contributes to hepatocellular carcinoma tumorigenesis by activating the Wnt/β-catenin signaling pathway.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0082-5
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- Article
Dual inhibition of CDK4 and FYN leads to selective cell death in KRAS-mutant colorectal cancer.
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- 2019
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- Publication type:
- Letter
The roles of exosomal miRNAs and lncRNAs in lung diseases.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0080-7
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- Publication type:
- Article
Tumor-suppressive function and mechanism of HOXB13 in right-sided colon cancer.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0086-1
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- Article
Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0078-1
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- Article
Unbiased screening reveals that blocking exportin 1 overcomes resistance to PI3Kα inhibition in breast cancer.
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- 2019
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- Publication type:
- Letter
Chemical compound cinobufotalin potently induces FOXO1-stimulated cisplatin sensitivity by antagonizing its binding partner MYH9.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0084-3
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- Article
PCDH17 increases the sensitivity of colorectal cancer to 5-fluorouracil treatment by inducing apoptosis and autophagic cell death.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0087-0
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- Article
Coagulation factors: a novel class of endogenous host antimicrobial proteins against drug-resistant gram-negative bacteria.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0083-4
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- Article
Simultaneous cotargeting of ATR and RNA Polymerase I transcription demonstrates synergistic antileukemic effects on acute myeloid leukemia.
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- 2019
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- Publication type:
- Letter
Clonal replacement of novel T cells: a new phenomenon in the tumor microenvironment following PD-1 blockade.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0077-2
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- Article
Targeting cell signaling in allergic asthma.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0079-0
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- Article
The interrelationship between cerebral ischemic stroke and glioma: a comprehensive study of recent reports.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0075-4
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- Article
Demystifying the manipulation of host immunity, metabolism, and extraintestinal tumors by the gut microbiome.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0074-5
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Global profiling of O-GlcNAcylated and/or phosphorylated proteins in hepatoblastoma.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0067-4
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- Article
The antimicrobial peptide PFR induces necroptosis mediated by ER stress and elevated cytoplasmic calcium and mitochondrial ROS levels: cooperation with Ara-C to act against acute myeloid leukemia.
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- 2019
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- Publication type:
- Letter
Allelic frequency differences of DAOA variants between Caucasians and Asians and their association with major mood disorders.
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- 2019
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- Publication type:
- Letter
Author Correction: History and progress of hypotheses and clinical trials for Alzheimer's disease.
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- 2019
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- Correction Notice
BE-PIGS: a base-editing tool with deaminases inlaid into Cas9 PI domain significantly expanded the editing scope.
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- 2019
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- Publication type:
- Letter
Genetically engineered T cells for cancer immunotherapy.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0070-9
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- Publication type:
- Article
Targeted therapeutic options and future perspectives for HER2-positive breast cancer.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0069-2
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- Article
E6-induced selective translation of WNT4 and JIP2 promotes the progression of cervical cancer via a noncanonical WNT signaling pathway.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0060-y
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- Article
Local delivery of arsenic trioxide nanoparticles for hepatocellular carcinoma treatment.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0062-9
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- Article
Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0068-3
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- Publication type:
- Article
The effect of selective serotonin reuptake inhibitors on cognitive function in patients with Alzheimer's disease and vascular dementia: focusing on fluoxetine with long follow-up periods.
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- 2019
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- Publication type:
- Letter
Author Correction: A novel cancer vaccine with the ability to simultaneously produce anti-PD-1 antibody and GM-CSF in cancer cells and enhance Th1-biased antitumor immunity.
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- 2019
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- Publication type:
- Correction Notice
History and progress of hypotheses and clinical trials for Alzheimer's disease.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0063-8
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- Publication type:
- Article
miR-124/VAMP3 is a novel therapeutic target for mitigation of surgical trauma-induced microglial activation.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0061-x
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- Article
Potent delivery of an MMP inhibitor to the tumor microenvironment with thermosensitive liposomes for the suppression of metastasis and angiogenesis.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0054-9
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- Article
Jumonji domain-containing 6 (JMJD6) identified as a potential therapeutic target in ovarian cancer.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0055-8
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- Article
The proatherosclerotic function of indoleamine 2, 3-dioxygenase 1 in the developmental stage of atherosclerosis.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0058-5
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- Article
EGFR TKIs impair lysosome-dependent degradation of SQSTM1 to compromise the effectiveness in lung cancer.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0059-4
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- Article
Genome-wide identification of DNA-PKcs-associated RNAs by RIP-Seq.
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- 2019
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- Publication type:
- Letter
ReishiMax inhibits mTORC1/2 by activating AMPK and inhibiting IGFR/PI3K/Rheb in tumor cells.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0056-7
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- Publication type:
- Article
Effects of insulin and pathway inhibitors on the PI3K-Akt-mTOR phosphorylation profile in acute myeloid leukemia cells.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0050-0
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- Publication type:
- Article
Structural basis for the acetylation of histone H3K9 and H3K27 mediated by the histone chaperone Vps75 in Pneumocystis carinii.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0047-8
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- Article
PD-L1 in the palm of your hand: palmitoylation as a target for immuno-oncology.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0053-x
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- Article
Deciphering the regulatory and catalytic mechanisms of an unusual SAM-dependent enzyme.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0052-y
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- Publication type:
- Article
Pazopanib in advanced soft tissue sarcomas.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0049-6
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- Article
Serotonylation: A novel histone H3 marker.
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- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0048-7
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- Article