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Correction: M2 macrophages, but not M1 macrophages, support megakaryopoiesis by upregulating PI3K-AKT pathway activity.
- Published in:
- 2024
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- Publication type:
- Correction Notice
Sex difference in human diseases: mechanistic insights and clinical implications.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01929-7
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- Publication type:
- Article
Metabolic inflexibility of mitochondria: beneficial for the fitness of regenerating liver cells.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01959-1
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- Publication type:
- Article
Anti-PD-L1 antibody ASC22 in combination with a histone deacetylase inhibitor chidamide as a "shock and kill" strategy for ART-free virological control: a phase II single-arm study.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01943-9
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- Publication type:
- Article
A new paradigm for generating high-quality cardiac pacemaker cells from mouse pluripotent stem cells.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01942-w
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- Publication type:
- Article
Elimination of mutant SWI/SNF complexes by protein quality control: new opportunities targeting aggressive rhabdoid tumours.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01935-9
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- Publication type:
- Article
"Clone-specific" antibody-drug conjugates: an innovative strategy in the treatment of T-cell cancers.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01945-7
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- Publication type:
- Article
Sintilimab (anti-PD-1 antibody) combined with high-dose methotrexate, temozolomide, and rituximab (anti-CD20 antibody) in primary central nervous system lymphoma: a phase 2 study.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01941-x
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- Publication type:
- Article
A phase II clinical trial of toripalimab in advanced solid tumors with polymerase epsilon/polymerase delta (POLE/POLD1) mutation.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01939-5
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- Publication type:
- Article
Circulating tumor cells: from new biological insights to clinical practice.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01938-6
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- Publication type:
- Article
Mind-body control: a new perspective on motor neuron function.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01922-0
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- Publication type:
- Article
Opioid receptors: single molecule studies shed light on mechanisms of efficacy.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01920-2
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- Publication type:
- Article
Predicting gastric cancer response to anti-HER2 therapy or anti-HER2 combined immunotherapy based on multi-modal data.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01932-y
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- Publication type:
- Article
Enhancing RBD exposure and S1 shedding by an extremely conserved SARS-CoV-2 NTD epitope.
- Published in:
- 2024
- By:
- Publication type:
- Letter
The JAK-STAT pathway: from structural biology to cytokine engineering.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01934-w
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- Publication type:
- Article
Annexin A1 binds PDZ and LIM domain 7 to inhibit adipogenesis and prevent obesity.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01930-0
- By:
- Publication type:
- Article
An emerging artificial nanomachine: a nanoengine with a reversible clutch.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01919-9
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- Publication type:
- Article
Recent advances in Alzheimer's disease: Mechanisms, clinical trials and new drug development strategies.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01911-3
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- Publication type:
- Article
Hyperuricemia and its related diseases: mechanisms and advances in therapy.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01916-y
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- Publication type:
- Article
Immune recall enhances cross-reactive antibody longevity after a large wave of SARS-CoV-2 breakthrough infection.
- Published in:
- 2024
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- Publication type:
- Letter
Biofilms and exopolysaccharides in Pseudomonas aeruginosa: pathogenesis, immune evasion, and lung–brain signaling during pneumonia.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01902-4
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- Publication type:
- Article
Potassium voltage-gated channel subfamily H member 2 (KCNH2) is a promising target for incretin secretagogue therapies.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01923-z
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- Publication type:
- Article
Branched-chain amino acid transaminase 1 confers EGFR-TKI resistance through epigenetic glycolytic activation.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01928-8
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- Publication type:
- Article
Robust neutralizing antibody response to the XBB.1.5 trivalent recombinant protein vaccine booster.
- Published in:
- 2024
- By:
- Publication type:
- Letter
Novel pathomechanistic insights into lysosomal storage disorders: how neuron-intrinsic cGAS-STING signaling drives disease progression.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01901-5
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- Publication type:
- Article
MYC and KRAS cooperation: from historical challenges to therapeutic opportunities in cancer.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01907-z
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- Publication type:
- Article
Drug tolerant persister cell plasticity in cancer: A revolutionary strategy for more effective anticancer therapies.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01891-4
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- Publication type:
- Article
Gefitinib (an EGFR tyrosine kinase inhibitor) plus anlotinib (an multikinase inhibitor) for untreated, EGFR-mutated, advanced non-small cell lung cancer (FL-ALTER): a multicenter phase III trial.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01927-9
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- Publication type:
- Article
Therapeutic advances of targeting receptor tyrosine kinases in cancer.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01899-w
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- Publication type:
- Article
LIM-domain-only 4 (LMO4) enhances CD8<sup>+</sup> T-cell stemness and tumor rejection by boosting IL-21-STAT3 signaling.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01915-z
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- Publication type:
- Article
Ribosomal modification protein rimK-like family member A activates betaine-homocysteine S-methyltransferase 1 to ameliorate hepatic steatosis.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01914-0
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- Publication type:
- Article
Single cell whole-genome sequencing of brain cells: age- and cell-type specific mutational profiles.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01892-3
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- Publication type:
- Article
Ribosomal modification protein rimK-like family member A activates betaine-homocysteine S-methyltransferase 1 to ameliorate hepatic steatosis.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01914-0
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- Publication type:
- Article
Current advance of nanotechnology in diagnosis and treatment for malignant tumors.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01889-y
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- Publication type:
- Article
Cell–cell communication: new insights and clinical implications.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01888-z
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- Publication type:
- Article
Targeting Lactobacillus johnsonii to reverse chronic kidney disease.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01913-1
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- Publication type:
- Article
Nascent mRNA damage: depot and disposal.
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- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01900-6
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- Publication type:
- Article
Glycosylation: mechanisms, biological functions and clinical implications.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01886-1
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- Publication type:
- Article
Mechanism insights and therapeutic intervention of tumor metastasis: latest developments and perspectives.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01885-2
- By:
- Publication type:
- Article
Intranasal adenovirus-vectored Omicron vaccine induced nasal immunoglobulin A has superior neutralizing potency than serum antibodies.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01906-0
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- Publication type:
- Article
Microglial complex I activity: a crucial factor for smoldering inflammation in the central nervous system.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01894-1
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- Publication type:
- Article
Intranasal adenovirus-vectored Omicron vaccine induced nasal immunoglobulin A has superior neutralizing potency than serum antibodies.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01906-0
- By:
- Publication type:
- Article
Microglial complex I activity: a crucial factor for smoldering inflammation in the central nervous system.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01894-1
- By:
- Publication type:
- Article
Revealing the crucial roles of suppressive immune microenvironment in cardiac myxoma progression.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01912-2
- By:
- Publication type:
- Article
Hypoxia-induced nuclear localization of ubiquinol-cytochrome-c reductase complex assembly factor 3 (UQCC3) in hepatocellular carcinoma.
- Published in:
- 2024
- By:
- Publication type:
- Letter
Synthetic lethality by PARP inhibitors: new mechanism uncovered based on unresolved transcription-replication conflicts.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01893-2
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- Publication type:
- Article
Adhesion G protein-coupled receptor latrophilin 1 (ADGRL1): a novel regulator of glucose and energy homeostasis.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01925-x
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- Publication type:
- Article
Proximity-dependent protein (de)stabilization: screening the human ORFeome for protein degraders and stabilizers.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01884-3
- By:
- Publication type:
- Article
CDC7 inhibition impairs neuroendocrine transformation in lung and prostate tumors through MYC degradation.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01908-y
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- Publication type:
- Article
Sensory neurons: unveiling the symphony of wound healing.
- Published in:
- Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01880-7
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- Publication type:
- Article