Works in Acta Neuropathologica Communications, 2021, Vol 9, Issue 1

Results: 213

High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01282-8

By:

Russo, Marco J.;
Orru, Christina D.;
Concha-Marambio, Luis;
Giaisi, Simone;
Groveman, Bradley R.;
Farris, Carly M.;
Holguin, Bret;
Hughson, Andrew G.;
LaFontant, David-Erick;
Caspell-Garcia, Chelsea;
Coffey, Christopher S.;
Mollon, Jennifer;
Hutten, Samantha J.;
Merchant, Kalpana;
Heym, Roland G.;
Soto, Claudio;
Caughey, Byron;
Kang, Un Jung

Publication type:

Article

De novo pathogenic variant in SETX causes a rapidly progressive neurodegenerative disorder of early childhood-onset with severe axonal polyneuropathy.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01277-5

By:

Hadjinicolaou, Aristides;
Ngo, Kathie J.;
Conway, Daniel Y.;
Provias, John P.;
Baker, Steven K.;
Brady, Lauren I.;
Bennett, Craig L.;
La Spada, Albert R.;
Fogel, Brent L.;
Yoon, Grace

Publication type:

Article

Clinically aggressive pediatric spinal ependymoma with novel MYC amplification demonstrates molecular and histopathologic similarity to newly described MYCN-amplified spinal ependymomas.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01296-2

By:

Shatara, Margaret;
Schieffer, Kathleen M.;
Klawinski, Darren;
Thomas, Diana L.;
Pierson, Christopher R.;
Sribnick, Eric A.;
Jones, Jeremy;
Rodriguez, Diana P.;
Deeg, Carol;
Hamelberg, Elizabeth;
LaHaye, Stephanie;
Miller, Katherine E.;
Fitch, James;
Kelly, Benjamin;
Leraas, Kristen;
Pfau, Ruthann;
White, Peter;
Magrini, Vincent;
Wilson, Richard K.;
Mardis, Elaine R.

Publication type:

Article

Machine learning modeling of genome-wide copy number alteration signatures reliably predicts IDH mutational status in adult diffuse glioma.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01295-3

By:

Nuechterlein, Nicholas;
Shapiro, Linda G.;
Holland, Eric C.;
Cimino, Patrick J.

Publication type:

Article

Emergence of distinct and heterogeneous strains of amyloid beta with advanced Alzheimer's disease pathology in Down syndrome.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01298-0

By:

Maxwell, Alison M.;
Yuan, Peng;
Rivera, Brianna M.;
Schaaf, Wilder;
Mladinov, Mihovil;
Prasher, Vee P.;
Robinson, Andrew C.;
DeGrado, William F.;
Condello, Carlo

Publication type:

Article

APOE ε4 associates with increased risk of severe COVID-19, cerebral microhaemorrhages and post-COVID mental fatigue: a Finnish biobank, autopsy and clinical study.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01302-7

By:

Kurki, Samu N.;
Kantonen, Jonas;
Kaivola, Karri;
Hokkanen, Laura;
Mäyränpää, Mikko I.;
Puttonen, Henri;
Martola, Juha;
Pöyhönen, Minna;
Kero, Mia;
Tuimala, Jarno;
Carpén, Olli;
Kantele, Anu;
Vapalahti, Olli;
Tiainen, Marjaana;
Tienari, Pentti J.;
Kaila, Kai;
Hästbacka, Johanna;
Myllykangas, Liisa

Publication type:

Article

IDH-wild type glioblastomas featuring at least 30% giant cells are characterized by frequent RB1 and NF1 alterations and hypermutation.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01304-5

By:

Barresi, Valeria;
Simbolo, Michele;
Mafficini, Andrea;
Martini, Maurizio;
Calicchia, Martina;
Piredda, Maria Liliana;
Ciaparrone, Chiara;
Bonizzato, Giada;
Ammendola, Serena;
Caffo, Maria;
Pinna, Giampietro;
Sala, Francesco;
Lawlor, Rita Teresa;
Ghimenton, Claudio;
Scarpa, Aldo

Publication type:

Article

Assembly of α-synuclein and neurodegeneration in the central nervous system of heterozygous M83 mice following the peripheral administration of α-synuclein seeds.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01291-7

By:

Macdonald, Jennifer A.;
Chen, John L.;
Masuda-Suzukake, Masami;
Schweighauser, Manuel;
Jaunmuktane, Zane;
Warner, Thomas;
Holton, Janice L.;
Grossman, Annabelle;
Berks, Richard;
Lavenir, Isabelle;
Goedert, Michel

Publication type:

Article

Assembly of α-synuclein and neurodegeneration in the central nervous system of heterozygous M83 mice following the peripheral administration of α-synuclein seeds.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01291-7

By:

Macdonald, Jennifer A.;
Chen, John L.;
Masuda-Suzukake, Masami;
Schweighauser, Manuel;
Jaunmuktane, Zane;
Warner, Thomas;
Holton, Janice L.;
Grossman, Annabelle;
Berks, Richard;
Lavenir, Isabelle;
Goedert, Michel

Publication type:

Article

Neurodegenerative brain changes are associated with area deprivation in the United Kingdom: findings from the Brains for Dementia Research study.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01301-8

By:

Hamilton, Calum A.;
Matthews, Fiona E.;
Erskine, Daniel;
Attems, Johannes;
Thomas, Alan J.

Publication type:

Article

Temporal patterns of microglial activation in white matter following experimental mild traumatic brain injury: a systematic literature review.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01297-1

By:

Velayudhan, Prashanth S.;
Schwab, Nicole;
Hazrati, Lili-Naz;
Wheeler, Anne L.

Publication type:

Article

MiR-212-3p functions as a tumor suppressor gene in group 3 medulloblastoma via targeting nuclear factor I/B (NFIB).

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01299-z

By:

Perumal, Naveenkumar;
Kanchan, Ranjana K.;
Doss, David;
Bastola, Noah;
Atri, Pranita;
Chirravuri-Venkata, Ramakanth;
Thapa, Ishwor;
Vengoji, Raghupathy;
Maurya, Shailendra K.;
Klinkebiel, David;
Talmon, Geoffrey A.;
Nasser, Mohd W.;
Batra, Surinder K.;
Mahapatra, Sidharth

Publication type:

Article

Impaired SorLA maturation and trafficking as a new mechanism for SORL1 missense variants in Alzheimer disease.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01294-4

By:

Rovelet-Lecrux, Anne;
Feuillette, Sebastien;
Miguel, Laetitia;
Schramm, Catherine;
Pernet, Ségolène;
Quenez, Olivier;
Ségalas-Milazzo, Isabelle;
Guilhaudis, Laure;
Rousseau, Stéphane;
Riou, Gaëtan;
Frébourg, Thierry;
Campion, Dominique;
Nicolas, Gaël;
Lecourtois, Magalie

Publication type:

Article

STAT3 inhibitor mitigates cerebral amyloid angiopathy and parenchymal amyloid plaques while improving cognitive functions and brain networks.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01293-5

By:

Mehla, Jogender;
Singh, Itender;
Diwan, Deepti;
Nelson, James W.;
Lawrence, Molly;
Lee, Eunjae;
Bauer, Adam Q.;
Holtzman, David M.;
Zipfel, Gregory J.

Publication type:

Article

The α-dystrobrevins play a key role in maintaining the structure and function of the extracellular matrix–significance for protein elimination failure arteriopathies.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01274-8

By:

Sharp, Matthew MacGregor;
Cassidy, Jordan;
Thornton, Thomas;
Lyles, James;
Keable, Abby;
Gatherer, Maureen;
Yasui, Masato;
Abe, Yoichiro;
Shibata, Shinsuke;
Weller, Roy O.;
Górecki, Dariusz C.;
Carare, Roxana O.

Publication type:

Article

α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant response.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01209-3

By:

Delaidelli, Alberto;
Richner, Mette;
Jiang, Lixiang;
van der Laan, Amelia;
Bergholdt Jul Christiansen, Ida;
Ferreira, Nelson;
Nyengaard, Jens R.;
Vægter, Christian B.;
Jensen, Poul H.;
Mackenzie, Ian R.;
Sorensen, Poul H.;
Jan, Asad

Publication type:

Article

Neuropathological hallmarks of fetal hydrocephalus linked to CCDC88C pathogenic variants.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01207-5

By:

Marguet, Florent;
Vezain, Myriam;
Marcorelles, Pascale;
Audebert-Bellanger, Séverine;
Cassinari, Kévin;
Drouot, Nathalie;
Chambon, Pascal;
Gonzalez, Bruno J.;
Horowitz, Arie;
Laquerriere, Annie;
Saugier-Veber, Pascale

Publication type:

Article

Correction to: High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease.

Published in:

2021

By:

Russo, Marco J.;
Orru, Christina D.;
Concha-Marambio, Luis;
Giaisi, Simone;
Groveman, Bradley R.;
Farris, Carly M.;
Holguin, Bret;
Hughson, Andrew G.;
LaFontant, David-Erick;
Caspell-Garcia, Chelsea;
Cofey, Christopher S.;
Mollon, Jennifer;
Hutten, Samantha J.;
Merchant, Kalpana;
Heym, Roland G.;
Soto, Claudio;
Caughey, Byron;
Kang, Un Jung

Publication type:

Correction Notice

Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01288-2

By:

Marotta, Nicholas P.;
Ara, Jahan;
Uemura, Norihito;
Lougee, Marshall G.;
Meymand, Emily S.;
Zhang, Bin;
Petersson, E. James;
Trojanowski, John Q.;
Lee, Virginia M.-Y.

Publication type:

Article

Neuropathology of SCA34 showing widespread oligodendroglial pathology with vacuolar white matter degeneration: a case study.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01272-w

By:

Ozaki, Kokoro;
Irioka, Takashi;
Uchihara, Toshiki;
Yamada, Akane;
Nakamura, Ayako;
Majima, Takamasa;
Igarashi, Susumu;
Shintaku, Hiroshi;
Yakeishi, Mayumi;
Tsuura, Yukio;
Okazaki, Yasushi;
Ishikawa, Kinya;
Yokota, Takanori

Publication type:

Article

Deep learning assisted quantitative assessment of histopathological markers of Alzheimer's disease and cerebral amyloid angiopathy.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01235-1

By:

Perosa, Valentina;
Scherlek, Ashley A.;
Kozberg, Mariel G.;
Smith, Lindsey;
Westerling-Bui, Thomas;
Auger, Corinne A.;
Vasylechko, Serge;
Greenberg, Steven M.;
van Veluw, Susanne J.

Publication type:

Article

Absence of Apolipoprotein E is associated with exacerbation of prion pathology and promotes microglial neurodegenerative phenotype.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01261-z

By:

Pankiewicz, Joanna E.;
Lizińczyk, Anita M.;
Franco, Leor A.;
Diaz, Jenny R.;
Martá-Ariza, Mitchell;
Sadowski, Martin J.

Publication type:

Article

Prion type 2 selection in sporadic Creutzfeldt–Jakob disease affecting peripheral ganglia.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01286-4

By:

Hofmann, Anna;
Wrede, Arne;
Jürgens-Wemheuer, Wiebke M.;
Schulz-Schaeffer, Walter J.

Publication type:

Article

Assembly of α-synuclein and neurodegeneration in the central nervous system of heterozygous M83 mice following the peripheral administration of α-synuclein seeds.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01291-7

By:

Macdonald, Jennifer A.;
Chen, John L.;
Masuda-Suzukake, Masami;
Schweighauser, Manuel;
Jaunmuktane, Zane;
Warner, Thomas;
Holton, Janice L.;
Grossman, Annabelle;
Berks, Richard;
Lavenir, Isabelle;
Goedert, Michel

Publication type:

Article

RyR1-related myopathy mutations in ATP and calcium binding sites impair channel regulation.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01287-3

By:

Yuan, Qi;
Dridi, Haikel;
Clarke, Oliver B.;
Reiken, Steven;
Melville, Zephan;
Wronska, Anetta;
Kushnir, Alexander;
Zalk, Ran;
Sittenfeld, Leah;
Marks, Andrew R.

Publication type:

Article

Overexpression of Lin28A in neural progenitor cells in vivo does not lead to brain tumor formation but results in reduced spine density.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01289-1

By:

Middelkamp, Maximilian;
Ruck, Lisa;
Krisp, Christoph;
Sumisławski, Piotr;
Mohammadi, Behnam;
Dottermusch, Matthias;
Meister, Valerie;
Küster, Lukas;
Schlüter, Hartmut;
Windhorst, Sabine;
Neumann, Julia E.

Publication type:

Article

Retina tissue validation of optical coherence tomography determined outer nuclear layer loss in FTLD-tau.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01290-8

By:

Kim, Benjamin J.;
Lee, Vivian;
Lee, Edward B.;
Saludades, Adrienne;
Trojanowski, John Q.;
Dunaief, Joshua L.;
Grossman, Murray;
Irwin, David J.

Publication type:

Article

Chemogenetic modulation of sensory neurons reveals their regulating role in melanoma progression.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01273-9

By:

Costa, Pedro A. C.;
Silva, Walison N.;
Prazeres, Pedro H. D. M.;
Picoli, Caroline C.;
Guardia, Gabriela D. A.;
Costa, Alinne C.;
Oliveira, Mariana A.;
Guimarães, Pedro P. G.;
Gonçalves, Ricardo;
Pinto, Mauro C. X.;
Amorim, Jaime H.;
Azevedo, Vasco A. C.;
Resende, Rodrigo R.;
Russo, Remo C.;
Cunha, Thiago M.;
Galante, Pedro A. F.;
Mintz, Akiva;
Birbrair, Alexander

Publication type:

Article

Inhibition of LRRK2 kinase activity promotes anterograde axonal transport and presynaptic targeting of α-synuclein.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01283-7

By:

Brzozowski, Charlotte F.;
Hijaz, Baraa A.;
Singh, Vijay;
Gcwensa, Nolwazi Z.;
Kelly, Kaela;
Boyden, Edward S.;
West, Andrew B.;
Sarkar, Deblina;
Volpicelli-Daley, Laura A.

Publication type:

Article

Annotation of pituitary neuroendocrine tumors with genome-wide expression analysis.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01284-6

By:

Tebani, Abdellah;
Jotanovic, Jelena;
Hekmati, Neda;
Sivertsson, Åsa;
Gudjonsson, Olafur;
Edén Engström, Britt;
Wikström, Johan;
Uhlèn, Mathias;
Casar-Borota, Olivera;
Pontén, Fredrik

Publication type:

Article

Tyrosine 136 phosphorylation of α-synuclein aggregates in the Lewy body dementia brain: involvement of serine 129 phosphorylation by casein kinase 2.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01281-9

By:

Sano, Kazunori;
Iwasaki, Yasushi;
Yamashita, Yuta;
Irie, Keiichi;
Hosokawa, Masato;
Satoh, Katsuya;
Mishima, Kenichi

Publication type:

Article

High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson's disease.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01282-8

By:

Russo, Marco J.;
Orru, Christina D.;
Concha-Marambio, Luis;
Giaisi, Simone;
Groveman, Bradley R.;
Farris, Carly M.;
Holguin, Bret;
Hughson, Andrew G.;
LaFontant, David-Erick;
Caspell-Garcia, Chelsea;
Coffey, Christopher S.;
Mollon, Jennifer;
Hutten, Samantha J.;
Merchant, Kalpana;
Heym, Roland G.;
Soto, Claudio;
Caughey, Byron;
Kang, Un Jung

Publication type:

Article

P62 accumulates through neuroanatomical circuits in response to tauopathy propagation.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01280-w

By:

Blaudin de Thé, François-Xavier;
Lassus, Benjamin;
Schaler, Ari W.;
Fowler, Stephanie L.;
Goulbourne, Chris N.;
Jeggo, Ross;
Mannoury la Cour, Clotilde;
Millan, Mark J.;
Duff, Karen E.

Publication type:

Article

TP53 wild-type/PPM1D mutant diffuse intrinsic pontine gliomas are sensitive to a MDM2 antagonist.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01270-y

By:

Xu, Cheng;
Liu, Heng;
Pirozzi, Christopher J.;
Chen, Lee H.;
Greer, Paula K.;
Diplas, Bill H.;
Zhang, Liwei;
Waitkus, Matthew S.;
He, Yiping;
Yan, Hai

Publication type:

Article

CNS tumors with YWHAE:NUTM2 and KDM2B-fusions present molecular similarities to extra-CNS tumors having BCOR internal tandem duplication or alternative fusions.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01279-3

By:

Tauziède-Espariat, Arnault;
Pierron, Gaëlle;
Guillemot, Delphine;
Bochaton, Dorian;
Watson, Sarah;
Masliah-Planchon, Julien;
Vasiljevic, Alexandre;
Meurgey, Alexandra;
Chotard, Guillaume;
Hasty, Lauren;
Wahler, Ellen;
Lechapt, Emmanuèle;
Chrétien, Fabrice;
Grill, Jacques;
Bourdeaut, Franck;
Bouchoucha, Yassine;
Puget, Stéphanie;
Icher-de-Bouyn, Céline;
Jecko, Vincent;
Cardoen, Liesbeth

Publication type:

Article

Association between CSF alpha-synuclein seeding activity and genetic status in Parkinson's disease and dementia with Lewy bodies.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01276-6

By:

Brockmann, Kathrin;
Quadalti, Corinne;
Lerche, Stefanie;
Rossi, Marcello;
Wurster, Isabel;
Baiardi, Simone;
Roeben, Benjamin;
Mammana, Angela;
Zimmermann, Milan;
Hauser, Ann-Kathrin;
Deuschle, Christian;
Schulte, Claudia;
Waniek, Katharina;
Lachmann, Ingolf;
Sjödin, Simon;
Brinkmalm, Ann;
Blennow, Kaj;
Zetterberg, Henrik;
Gasser, Thomas;
Parchi, Piero

Publication type:

Article

A novel SMARCA2-CREM fusion: expanding the molecular spectrum of intracranial mesenchymal tumors beyond the FET genes.

Published in:

2021

By:

Tauziède-Espariat, Arnault;
Pierron, Gaëlle;
Guillemot, Delphine;
Sievers, Philipp;
Cazals-Hatem, Dominique;
Faillot, Thierry;
Roux, Alexandre;
Benzakoun, Joseph;
Bockel, Sophie;
Weinbreck, Nicolas;
Hasty, Lauren;
Lechapt, Emmanuèle;
Chrétien, Fabrice;
Varlet, Pascale

Publication type:

Case Study

Ex vivo MRI atlas of the human medial temporal lobe: characterizing neurodegeneration due to tau pathology.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01275-7

By:

Ravikumar, Sadhana;
Wisse, Laura E. M.;
Lim, Sydney;
Ittyerah, Ranjit;
Xie, Long;
Bedard, Madigan L.;
Das, Sandhitsu R.;
Lee, Edward B.;
Tisdall, M. Dylan;
Prabhakaran, Karthik;
Lane, Jacqueline;
Detre, John A.;
Mizsei, Gabor;
Trojanowski, John Q.;
Robinson, John L.;
Schuck, Theresa;
Grossman, Murray;
Artacho-Pérula, Emilio;
de Onzoño Martin, Maria Mercedes Iñiguez;
del Mar Arroyo Jiménez, María

Publication type:

Article

The association of Lewy bodies with limbic-predominant age-related TDP-43 encephalopathy neuropathologic changes and their role in cognition and Alzheimer's dementia in older persons.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01260-0

By:

Agrawal, Sonal;
Yu, Lei;
Nag, Sukriti;
Arfanakis, Konstantinos;
Barnes, Lisa L.;
Bennett, David A.;
Schneider, Julie A.

Publication type:

Article

MFG-E8 (LACTADHERIN): a novel marker associated with cerebral amyloid angiopathy.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01257-9

By:

Marazuela, Paula;
Solé, Montse;
Bonaterra-Pastra, Anna;
Pizarro, Jesús;
Camacho, Jessica;
Martínez-Sáez, Elena;
Kuiperij, H. Bea;
Verbeek, Marcel M.;
de Kort, Anna M.;
Schreuder, Floris H. B. M.;
Klijn, Catharina J. M.;
Castillo-Ribelles, Laura;
Pancorbo, Olalla;
Rodríguez-Luna, David;
Pujadas, Francesc;
Delgado, Pilar;
Hernández-Guillamon, Mar

Publication type:

Article

Importance of extracellular vesicle secretion at the blood–cerebrospinal fluid interface in the pathogenesis of Alzheimer's disease.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01245-z

By:

Vandendriessche, Charysse;
Balusu, Sriram;
Van Cauwenberghe, Caroline;
Brkic, Marjana;
Pauwels, Marie;
Plehiers, Nele;
Bruggeman, Arnout;
Dujardin, Pieter;
Van Imschoot, Griet;
Van Wonterghem, Elien;
Hendrix, An;
Baeke, Femke;
De Rycke, Riet;
Gevaert, Kris;
Vandenbroucke, Roosmarijn E.

Publication type:

Article

The α-dystrobrevins play a key role in maintaining the structure and function of the extracellular matrix–significance for protein elimination failure arteriopathies.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01274-8

By:

Sharp, Matthew MacGregor;
Cassidy, Jordan;
Thornton, Thomas;
Lyles, James;
Keable, Abby;
Gatherer, Maureen;
Yasui, Masato;
Abe, Yoichiro;
Shibata, Shinsuke;
Weller, Roy O.;
Górecki, Dariusz C.;
Carare, Roxana O.

Publication type:

Article

The α-dystrobrevins play a key role in maintaining the structure and function of the extracellular matrix–significance for protein elimination failure arteriopathies.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01274-8

By:

Sharp, Matthew MacGregor;
Cassidy, Jordan;
Thornton, Thomas;
Lyles, James;
Keable, Abby;
Gatherer, Maureen;
Yasui, Masato;
Abe, Yoichiro;
Shibata, Shinsuke;
Weller, Roy O.;
Górecki, Dariusz C.;
Carare, Roxana O.

Publication type:

Article

Deep learning reveals disease-specific signatures of white matter pathology in tauopathies.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01271-x

By:

Vega, Anthony R.;
Chkheidze, Rati;
Jarmale, Vipul;
Shang, Ping;
Foong, Chan;
Diamond, Marc I.;
White III, Charles L.;
Rajaram, Satwik

Publication type:

Article

Inefficient quality control of ribosome stalling during APP synthesis generates CAT-tailed species that precipitate hallmarks of Alzheimer's disease.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01268-6

By:

Rimal, Suman;
Li, Yu;
Vartak, Rasika;
Geng, Ji;
Tantray, Ishaq;
Li, Shuangxi;
Huh, Sungun;
Vogel, Hannes;
Glabe, Charles;
Grinberg, Lea T.;
Spina, Salvatore;
Seeley, William W.;
Guo, Su;
Lu, Bingwei

Publication type:

Article

TREM2 modulates differential deposition of modified and non-modified Aβ species in extracellular plaques and intraneuronal deposits.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01263-x

By:

Joshi, Pranav;
Riffel, Florian;
Kumar, Sathish;
Villacampa, Nàdia;
Theil, Sandra;
Parhizkar, Samira;
Haass, Christian;
Colonna, Marco;
Heneka, Michael T.;
Arzberger, Thomas;
Herms, Jochen;
Walter, Jochen

Publication type:

Article

Low-level blast exposure induces chronic vascular remodeling, perivascular astrocytic degeneration and vascular-associated neuroinflammation.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01269-5

By:

Gama Sosa, Miguel A.;
De Gasperi, Rita;
Pryor, Dylan;
Perez Garcia, Georgina S.;
Perez, Gissel M.;
Abutarboush, Rania;
Kawoos, Usmah;
Hogg, Seth;
Ache, Benjamin;
Janssen, William G.;
Sowa, Allison;
Tetreault, Timothy;
Cook, David G.;
Tappan, Susan J.;
Gandy, Sam;
Hof, Patrick R.;
Ahlers, Stephen T.;
Elder, Gregory A.

Publication type:

Article

White matter injury but not germinal matrix hemorrhage induces elevated osteopontin expression in human preterm brains.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01267-7

By:

Nilsson, Gisela;
Baburamani, Ana A.;
Rutherford, Mary A.;
Zhu, Changlian;
Mallard, Carina;
Hagberg, Henrik;
Vontell, Regina;
Wang, Xiaoyang

Publication type:

Article

Transmission of amyloid-beta and tau pathologies is associated with cognitive impairments in a primate.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01266-8

By:

Lam, Suzanne;
Petit, Fanny;
Hérard, Anne-Sophie;
Boluda, Susana;
Eddarkaoui, Sabiha;
Guillermier, Martine;
The Brain Bank Neuro-C. E. B. Neuropathology Network;
Letournel, Franck;
Martin-Négrier, Marie-Laure;
Faisant, Maxime;
Godfraind, Catherine;
Boutonnat, Jean;
Maurage, Claude-Alain;
Deramecourt, Vincent;
Duchesne, Mathilde;
Meyronet, David;
Fenouil, Tanguy;
de Paula, André Mauès;
Rigau, Valérie;
Vandenbos-Burel, Fanny

Publication type:

Article

Anatomic survey of seeding in Alzheimer's disease brains reveals unexpected patterns.

Published in:

Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01255-x

By:

Stopschinski, Barbara E.;
Del Tredici, Kelly;
Estill-Terpack, Sandi-Jo;
Ghebremdehin, Estifanos;
Yu, Fang F.;
Braak, Heiko;
Diamond, Marc I.

Publication type:

Article