Works in eLife, 2025

Results: 810

CRISPR-edited DPSCs constitutively expressing BDNF enhance dentin regeneration in injured teeth.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.105153

By:

Ji Hyun Kim;
Irfan, Muhammad;
Sreekumar, Sreelekshmi;
Phimon, Atsawasuwan;
Kim, Stephanie;
Seung Chung

Publication type:

Article

Molecular characterization of gustatory second-order neurons reveals integrative mechanisms of gustatory and metabolic information.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.100947

By:

Mollá-Albaladejo, Rubén;
Jiménez-Caballero, Manuel;
Sanchez-Alcaniz, Juan Antonio

Publication type:

Article

Prebiotic gas flow environment enables isothermal nucleic acid replication.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.100152

By:

Schwintek, Philipp;
Eren, Emre;
Bernhard Mast, Christof;
Braun, Dieter

Publication type:

Article

A temporally restricted function of the dopamine receptor Dop1R2 during memory formation.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.99368

By:

Kaldun, Jenifer C.;
Calia, Emanuele;
Bangalore Mukunda, Ganesh Chinmai;
Fritsch, Cornelia;
Komarov, Nikita;
Sprecher, Simon G.

Publication type:

Article

Fast evolution of SOS-independent multi-drug resistance in bacteria.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.95058

By:

Le Zhang;
Yunpeng Guan;
YuenYee Cheng;
Cokcetin, Nural N.;
Bottomley, Amy L.;
Robinson, Andrew;
Harry, Elizabeth J.;
van Oijen, Antoine M.;
Qian Peter Su;
Dayong Jin

Publication type:

Article

Returning aging cells to productivity.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.103073

By:

VAIDYA, RACHANA W.;
TANG, SIMON Y.

Publication type:

Article

Forward genetics in C. elegans reveals genetic adaptations to polyunsaturated fatty acid deficiency.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104181

By:

Kaper, Delaney;
Radović, Uroš;
Bergh, Per-Olof;
Qvist, August;
Henricsson, Marcus;
Borén, Jan;
Pilon, Marc

Publication type:

Article

Function and firing of the Streptomyces coelicolor contractile injection system requires the membrane protein CisA.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104064

By:

Casu, Bastien;
Sallmen, Joseph W.;
Haas, Peter E.;
Chandra, Govind;
Afanasyev, Pavel;
Jingwei Xu;
Pilhofer, Martin;
Schlimpert, Susan

Publication type:

Article

Humans adapt rationally to approximate estimates of uncertainty.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.103734

By:

Pulcu, Erdem;
Browning, Michael

Publication type:

Article

β-Glucan reprograms alveolar macrophages via neutrophil/IFNγ axis in a murine model of lung injury.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.102068

By:

Prevel, Renaud;
Pernet, Erwan;
Kim A. Tran;
Sadek, Abderrahmane;
Sadeghi, Mina;
Lapshina, Elizabeth;
Jurado, Leonardo F.;
Kristof, Arnold S.;
Moumni, Mohieddine;
Poschmann, Jeremie;
Divangahi, Maziar

Publication type:

Article

Unraveling CRP/cAMP-mediated metabolic regulation in Escherichia coli persister cells.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.99735

By:

Han G. Ngo;
Mohiuddin, Sayed Golam;
Ananda, Aina;
Orman, Mehmet

Publication type:

Article

Quantitative intra- Golgi transport and organization data suggest the stable compartment nature of the Golgi.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.98582

By:

Hieng Chiong Tie;
Haiyun Wang;
Mahajan, Divyanshu;
Yuen In Lam, Hilbert;
Xiuping Sun;
Bing Chen;
Yuguang Mu;
Lei Lu

Publication type:

Article

Diverse prey capture strategies in teleost larvae.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.98347

By:

Mearns, Duncan S.;
Hunt, Sydney A.;
Schneider, Martin W.;
Parker, Ash V.;
Stemmer, Manuel;
Baier, Herwig

Publication type:

Article

Heat stress induces phage tolerance in Enterobacteriaceae.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.105703

By:

Fan Zhang;
Hao-Ze Chen;
Bo Zheng;
Liang Huang;
Ye Xiang;
Jing-Ren Zhang;
Jia-Feng Liu

Publication type:

Article

The C-terminus of the multi-drug efflux pump EmrE prevents proton leak by gating transport.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.105525

By:

Brousseau, Merissa;
Da Teng;
Thomas, Nathan E.;
Voth, Gregory A.;
Henzler-Wildman, Katherine A.

Publication type:

Article

Magnetically steered cell therapy for reduction of intraocular pressure as a treatment strategy for open-angle glaucoma.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.103256

By:

Bahranifard, M. Reza;
Chan, Jessica;
Read, A. Thomas;
Guorong Li;
Lin Cheng;
Safa, Babak N.;
Siadat, Seyed Mohammad;
Jhunjhunwala, Anamik;
Grossniklaus, Hans E.;
Emelianov, Stanislav Y.;
Stamer, W. Daniel;
Kuehn, Markus H.;
Ethier, C. Ross

Publication type:

Article

The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101984

By:

Fan Zhang;
Yuan Wang;
Luyang Zhang;
Chunjie Wang;
Deping Chen;
Haibo Liu;
Ren Xu;
Haynes, Cole M.;
Jae-Hyuck Shim;
Xianpeng Ge

Publication type:

Article

The molecular logic of Gtr1/2- and Pib2-dependent TORC1 regulation in budding yeast.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.94628

By:

Cecil, Jacob H.;
Padilla, Cristina M.;
Lipinski, Austin A.;
Langlais, Paul;
Xiangxia Luo;
Capaldi, Andrew P.

Publication type:

Article

Highly sensitive in vivo detection of dynamic changes in enkephalins following acute stress in mice.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.91609

By:

Mikati, Marwa O.;
Erdmann-Gilmore, Petra;
Connors, Rose;
Conway, Sineadh M.;
Malone, Jim;
Woods, Justin;
Sprung, Robert W.;
Townsend, Reid R.;
Al-Hasani, Ream

Publication type:

Article

Drosophila hamlet mediates epithelial tissue assembly of the reproductive system.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104164

By:

Huazhen Wang;
Bertonnier-Brouty, Ludivine;
Artner, Isabella;
Jiayu Wen;
Qi Dai

Publication type:

Article

Multifaceted role of galanin in brain excitability.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.98634

By:

Rieser, Nicolas N.;
Ronchetti, Milena;
Lea Hotz, Adriana Lea;
Neuhauss, Stephan C. F.

Publication type:

Article

Competence for transcellular infection in the root cortex involves a postreplicative, cell-cycle exit decision in Medicago truncatula.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.88588

By:

Batzenschlager, Morgane;
Lace, Beatrice;
Ning Zhang;
Chao Su;
Boiger, Anna;
Egli, Sabrina;
Krohn, Pascal;
Salfeld, Jule;
Ditengou, Franck Anicet;
Laux, Thomas;
Ott, Thomas

Publication type:

Article

The interplay between homeostatic synaptic scaling and homeostatic structural plasticity maintains the robust firing rate of neural networks.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.88376

By:

Han Lu;
Diaz-Pier, Sandra;
Lenz, Maximilian;
Vlachos, Andreas

Publication type:

Article

Cestode larvae excite host neuronal circuits via glutamatergic signalling.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.88174

By:

de Lange, Anja;
Tomes, Hayley;
Selfe, Joshua S.;
Prodjinotho, Ulrich Fabien;
Verhoog, Matthijs B.;
Mahanty, Siddhartha;
Smith, Katherine Ann;
Horsnell, William;
Sikasunge, Chummy;
Prazeres da Costa, Clarissa;
Raimondo, Joseph V.

Publication type:

Article

Searching for druggable targets.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.107757

By:

Heganovic, Lana;
Passalacqua, Luiz F. M.

Publication type:

Article

Structural insights into heterohexameric assembly of epilepsy-related ligand–receptor complex LGI1–ADAM22.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.105918

By:

Takayuki Yamaguchi;
Kei Okatsu;
Masato Kubota;
Ayuka Mitsumori;
Atsushi Yamagata;
Yuko Fukata;
Masaki Fukata;
Mikihiro Shibata;
Shuya Fukai

Publication type:

Article

Human eIF2A has a minimal role in translation initiation and in uORF-mediated translational control in HeLa cells.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.105311

By:

Roiuk, Mykola;
Neff, Marilena;
Teleman, Aurelio A.

Publication type:

Article

Negative regulation of miRNA sorting into EVs is mediated by the capacity of RBP PCBP2 to impair the SYNCRIP-dependent miRNA loading.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.105017

By:

Marocco, Francesco;
Garbo, Sabrina;
Montaldo, Claudia;
Colantoni, Alessio;
Quattrocchi, Luca;
Gaboardi, Gioele;
Sabarese, Giovanna;
Cicchini, Carla;
Lecce, Mario;
Carnevale, Alessia;
Paolini, Rossella;
Tartaglia, Gian Gaetano;
Battistelli, Cecilia;
Tripodi, Marco

Publication type:

Article

Planar cell polarity coordination in a cnidarian embryo provides clues to animal body axis evolution.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104508

By:

Uveira, Julie;
Donati, Antoine;
Léria, Marvin;
Lechable, Marion;
Lahaye, François;
Vesque, Christine;
Houliston, Evelyn;
Tsuyoshi Momose

Publication type:

Article

Exploiting functional regions in the viral RNA genome as druggable entities.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.103923

By:

Dehua Luo;
Yingge Zheng;
Zhiyuan Huang;
Zi Wen;
Lijun Guo;
Yingxiang Deng;
Qingling Li;
Yuqing Bai;
Haider, Shozeb;
Dengguo Wei

Publication type:

Article

Hunger shifts attention and attribute weighting in dietary choice.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.103736

By:

March, Jennifer;
Gluth, Sebastian

Publication type:

Article

Inference technique for the synaptic conductances in rhythmically active networks and application to respiratory central pattern generation circuits.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101959

By:

Yaroslav Molkov;
Borgmann, Anke;
Hidehiko Koizumi;
Noriyuki Hama;
Ruli Zhang;
Smith, Jeffrey

Publication type:

Article

Modifying gene expression through passive forces.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.107575

By:

HALLSTEIN, SARAH;
KÖNIG, JULIAN

Publication type:

Article

Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104461

By:

Kremer, Laura Sophie;
Gao, Guanbin;
Rigoni, Giovanni;
Filograna, Roberta;
Mennuni, Mara;
Wibom, Rolf;
Végvári, Ákos;
Koolmeister, Camilla;
Larsson, Nils-Göran

Publication type:

Article

Expanding automated multiconformer ligand modeling to macrocycles and fragments.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.103797

By:

Flowers, Jessica;
Echols, Nathaniel;
Correy, Galen J.;
Jaishankar, Priyadarshini;
Togo, Takaya;
Renslo, Adam R.;
van den Bedem, Henry;
Fraser, James S.;
Wankowicz, Stephanie A.

Publication type:

Article

Evolution of lateralized gustation in nematodes.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.103796

By:

Mackie, Marisa;
Le, Vivian Vy;
Carstensen, Heather R.;
Kushnir, Nicole R.;
Castro, Dylan L.;
Dimov, Ivan M.;
Quach, Kathleen T.;
Cook, Steven J.;
Hobert, Oliver;
Chalasani, Sreekanth H.;
Hong, Ray L.

Publication type:

Article

CD131 contributes to ulcerative colitis pathogenesis by promoting macrophage infiltration.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.102637

By:

Zhiyuan Wu;
Lindi Liu;
Chenchen He;
Lin Xiao;
Duo Yun;
Junliang Chen;
Zhihao Liu;
Wenjun Li;
Qingjie Lv;
Xiaodong Tan

Publication type:

Article

Effects of experiencing the COVID-19 pandemic on optimistically biased belief updating.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101157

By:

Khalid, Iraj;
Morlaas, Orphee;
Bottemanne, Hugo;
Thonon, Lisa;
Da Costa, Thomas;
Fossati, Philippe;
Schmidt, Liane

Publication type:

Article

Passive shaping of intra- and intercellular m6A dynamics via mRNA metabolism.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.100448

By:

Dierks, David;
Shachar, Ran;
Nir, Ronit;
Garcia-Campos, Miguel Angel;
Uzonyi, Anna;
Wiener, David;
Toth, Ursula;
Rossmanith, Walter;
Lasman, Lior;
Slobodin, Boris;
Hanna, Jacob H.;
Antebi, Yaron;
Scherz-Shouval, Ruth;
Schwartz, Schraga

Publication type:

Article

Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IκBα through a phosphoenzyme intermediate.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.98009

By:

Borar, Prateeka;
Biswas, Tapan;
Chaudhuri, Ankur;
Rao, Pallavi T.;
Raychaudhuri, Swasti;
Huxford, Tom;
Chakrabarti, Saikat;
Ghosh, Gourisankar;
Polley, Smarajit

Publication type:

Article

Expansion-assisted selective plane illumination microscopy for nanoscale imaging of centimeter-scale tissues.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.91979

By:

Glaser, Adam;
Chandrashekar, Jayaram;
Vasquez, Sonya;
Arshadi, Cameron;
Javeri, Rajvi;
Ouellette, Naveen;
Xiaoyun Jiang;
Baka, Judith;
Kovacs, Gabor;
Woodard, Micah;
Seshamani, Shamishtaa;
Cao, Kevin;
Clack, Nathan;
Recknagel, Andrew;
Grim, Anna;
Balaram, Pooja;
Turschak, Emily;
Hooper, Marcus;
Liddell, Alan;
Rohde, John

Publication type:

Article

Sex chromosome gene expression associated with vocal learning following hormonal manipulation in female zebra finches.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.89425

By:

Davenport, Matthew;
Ha Na Choe;
Hiroaki Matsunami;
Jarvis, Erich

Publication type:

Article

TRPV4 activation by TGFβ2 enhances cellular contractility and drives ocular hypertension.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104894

By:

Rudzitis, Christopher Nass;
Lakk, Monika;
Singh, Ayushi;
Redmon, Sarah N.;
Kirdajová, Denisa;
Tseng, Yun-Ting;
De Ieso, Michael L.;
Stamer, W. Daniel;
Herberg, Samuel;
Krizaj, David

Publication type:

Article

Distinct neural bases of subcomponents of the attentional blink.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.97098

By:

Halder, Swagata;
Raya, Deepak Velgapuni;
Sridharan, Devarajan

Publication type:

Article

Striatal cholinergic interneuron pause response requires Kv1 channels, is absent in dyskinetic mice, and is restored by dopamine D5 receptor inverse agonism.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.102184

By:

Tubert, Cecilia;
Paz, Rodrigo Manuel;
Stahl, Agostina Mónica;
Sanchez Armijos, Kianny Miroslava;
Rela, Lorena;
Murer, Mario Gustavo

Publication type:

Article

Nonequilibrium polysome dynamics promote chromosome segregation and its coupling to cell growth in Escherichia coli.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104276

By:

Papagiannakis, Alexandros;
Qiwei Yu;
Govers, Sander K.;
Wei-Hsiang Lin;
Wingreen, Ned S.;
Jacobs-Wagner, Christine

Publication type:

Article

LC8 enhances 53BP1 foci through heterogeneous bridging of 53BP1 oligomers.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.102179

By:

Howe, Jesse;
Walker, Douglas;
Tengler, Kyle;
Sonpatki, Maya;
Reardon, Patrick N.;
Leung, Justin W. C.;
Barbar, Elisar J.

Publication type:

Article

Hypothermia protects against ventilatorinduced lung injury by limiting IL-1β release and NETs formation.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101990

By:

Nosaka, Nobuyuki;
Borges, Vanessa;
Martinon, Daisy;
Crother, Timothy R;
Arditi, Moshe;
Shimada, Kenichi

Publication type:

Article

The triad interaction of ULK1, ATG13, and FIP200 is required for ULK complex formation and autophagy.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101531

By:

Yutaro Hama;
Yuko Fujioka;
Hayashi Yamamoto;
Noboru Mizushima;
Noda, Nobuo N.

Publication type:

Article

Sigh generation in preBötzinger complex.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.100192

By:

Yan Cui;
Bondarenko, Evgeny;
Perez, Carolina Thörn;
Chiu, Delia N.;
Feldman, Jack L.

Publication type:

Article