Works in eLife, 2025

Results: 576

Adaptation of CD4 in gorillas and chimpanzees conveyed resistance to simian immunodeficiency viruses.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.93316

By:

Warren, Cody J.;
Barbachano-Guerrero, Arturo;
Bauer, Vanessa L.;
Stabell, Alex;
Dirasantha, Obaiah;
Qing Yang;
Sawyer, Sara L.

Publication type:

Article

Molecular requirements for C. elegans transgenerational epigenetic inheritance of pathogen avoidance.

Published in:

eLife, 2025, p. 1

By:

Kaletsky, Rachel;
Moore, Rebecca S.;
Sengupta, Titas;
Seto, Renee;
Ceballos-Llera, Borja;
Murphy, Coleen T.

Publication type:

Article

AARS2 ameliorates myocardial ischemia via fine-tuning PKM2-mediated metabolism.

Published in:

eLife, 2025, p. 1

By:

Zongwang Zhang;
Lixia Zheng;
Yang Chen;
Yuanyuan Chen;
Junjie Hou;
Chenglu Xiao;
Xiaojun Zhu;
Shi-Min Zhao;
Jing-Wei Xiong

Publication type:

Article

Sensorimotor delays constrain robust locomotion in a 3D kinematic model of fly walking.

Published in:

eLife, 2025, p. 1

By:

Karashchuk, Lili;
Jing Shuang Li;
Chou, Grant M.;
Walling-Bell, Sarah;
Brunton, Steven L.;
Tuthill, John C.;
Brunton, Bingni W.

Publication type:

Article

Rudhira-mediated microtubule stability controls TGFβ signaling during mouse vascular development.

Published in:

eLife, 2025, p. 1

By:

Joshi, Divyesh;
Jindal, Preeti;
Shetty, Ronak K.;
Inamdar, Maneesha S.

Publication type:

Article

Single nuclei RNA-sequencing of adult brain neurons derived from type 2 neuroblasts reveals transcriptional complexity in the insect central complex.

Published in:

eLife, 2025, p. 1

By:

Epiney, Derek G.;
Morales Chaya, Gonzalo;
Dillon, Noah R.;
Sen-Lin Lai;
Doe, Chris Q.

Publication type:

Article

Trends in self-citation rates in highimpact neurology, neuroscience, and psychiatry journals.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.88540

By:

Rosenblatt, Matthew;
Mehta, Saloni;
Peterson, Hannah;
Dadashkarimi, Javid;
Rodriguez, Raimundo;
Foster, Maya L.;
Adkinson, Brendan D.;
Liang, Qinghao;
Kimble, Violet M.;
Ye, Jean;
McCusker, Marie C.;
Farruggia, Michael C.;
Rolison, Max J.;
Westwater, Margaret L.;
Jiang, Rongtao;
Noble, Stephanie;
Scheinost, Dustin

Publication type:

Article

scRNA-seq and scATAC-seq reveal that Sertoli cell mediates spermatogenesis disorders through stage-specific communications in non-obstructive azoospermia.

Published in:

eLife, 2025, p. 1

By:

Shimin Wang;
Hongxian Wang;
Bicheng Jin;
Hongli Yan;
Qingliang Zheng;
Dong Zhao

Publication type:

Article

Mapping serotonergic dynamics using drug-modulated molecular connectivity in rats.

Published in:

eLife, 2025, p. 1

By:

Ionescu, Tudor M.;
Amend, Mario;
Hafiz, Rakibul;
Maurer, Andreas;
Biswal, Bharat;
Wehrl, Hans F.;
Herfert, Kristina

Publication type:

Article

Structure, function and assembly of soybean primary cell wall cellulose synthases.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.96704

By:

Ho, Ruoya;
Pallinti, Purushotham;
Wilson, Louis F. L.;
Wan, Yueping;
Zimmer, Jochen

Publication type:

Article

SARS-CoV-2 nsp16 is regulated by host E3 ubiquitin ligases, UBR5 and MARCHF7.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.102277

By:

Li Tian;
Zongzheng Zhao;
Wenying Gao;
Zirui Liu;
Xiao Li;
Wenyan Zhang;
Zhaolong Li

Publication type:

Article

Reprogramming of GM-CSF-dependent alveolar macrophages through GSK3 activity modulation.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.102659

By:

Ríos, Israel;
Herrero, Cristina;
Torres-Torresano, Mónica;
López-Navarro, Baltasar;
Teresa Schiaffino, María;
Díaz Crespo, Francisco;
Nieto-Valle, Alicia;
Samaniego, Rafael;
Sierra-Palomares, Yolanda;
Oliver, Eduardo;
Revuelta-Salgado, Fernando;
García-Luján, Ricardo;
Sánchez-Mateos, Paloma;
Delgado, Rafael;
Puig-Kröger, Amaya;
Corbí, Angel L.

Publication type:

Article

Thymic dendritic cell-derived IL-27p28 promotes the establishment of functional bias against IFN-γ production in newly generated CD4+ T cells through STAT1- related epigenetic mechanisms.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.96868

By:

Jie Zhang;
Hui Tang;
Haoming Wu;
Xuewen Pang;
Rong Jin;
Yu Zhang

Publication type:

Article

Transcriptional pattern enriched for synaptic signaling is associated with shorter survival of patients with high-grade serous ovarian cancer.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101369

By:

Bhattacharya, Arkajyoti;
Stutvoet, Thijs S.;
Perla, Mirela;
Loipfinger, Stefan;
Jalving, Mathilde;
Reyners, Anna K. L.;
Vermeer, Paola D.;
Drapkin, Ronny;
de Bruyn, Marco;
de Vries, Elisabeth G. E.;
de Jong, Steven;
Fehrmann, Rudolf S. N.

Publication type:

Article

Maternal behavior influences vocal practice and learning processes in the greater sac-winged bat.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.99474

By:

Aurora Fernandez, Ahana;
Serve, Nora;
Fabian, Sarah-Cecil;
Knörnschild, Mirjam

Publication type:

Article

PIM kinase control of CD8 T cell protein synthesis and cell trafficking.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.98622

By:

Marchingo, Julia M.;
Spinelli, Laura;
Pathak, Shalini;
Cantrell, Doreen A.

Publication type:

Article

Role of posterior medial thalamus in the modulation of striatal circuitry and choice behavior.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.98563

By:

Yonk, Alex J.;
Linares-García, Ivan;
Pasternak, Logan;
Juliani, Sofia E.;
Gradwell, Mark A.;
George, Arlene J.;
Margolis, David J.

Publication type:

Article

Convolutional networks can model the functional modulation of the MEG responses associated with feed-forward processes during visual word recognition.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.96217

By:

van Vliet, Marijn;
Rinkinen, Oona;
Shimizu, Takao;
Niskanen, Anni-Mari;
Devereux, Barry;
Salmelin, Riitta

Publication type:

Article

Dual-color optical activation and suppression of neurons with high temporal precision.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.90327

By:

Mermet-Joret, Noëmie;
Moreno, Andrea;
Zbela, Agnieszka;
Nazari, Milad;
Ellendersen, Bárður Eyjólfsson;
Baro, Raquel Comaposada;
Krauth, Nathalie;
von Philipsborn, Anne;
Sørensen, Andreas Toft;
Piriz, Joaquin;
John Yu-luen Lin;
Nabavi, Sadegh

Publication type:

Article

Observation of persister cell histories reveals diverse modes of survival in antibiotic persistence.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.79517

By:

Miki Umetani;
Miho Fujisawa;
Reiko Okura;
Takashi Nozoe;
Shoichi Suenaga;
Hidenori Nakaoka;
Kussell, Edo;
Yuichi Wakamoto

Publication type:

Article

Epidermal cells and sensory neurons team up.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.107113

By:

BOIVIN, JEAN-CHRISTOPHE;
OHYAMA, TOMOKO

Publication type:

Article

Selective attention and sensitivity to auditory disturbances in a virtually real classroom.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.103235

By:

Levy, Orel;
Hackmon, Shirley Libman;
Zvilichovsky, Yair;
Korisky, Adi;
Bidet-Caulet, Aurelie;
Schweitzer, Julie B;
Golumbic, Elana Zion

Publication type:

Article

Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2G2019S model of Parkinson’s disease.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101035

By:

Gaertner, Zachary;
Oram, Cameron;
Schneeweis, Amanda;
Schonfeld, Elan;
Bolduc, Cyril;
Chen, Chuyu;
Dombeck, Daniel;
Parisiadou, Loukia;
Poulin, Jean-Francois;
Awatramani, Rajeshwar

Publication type:

Article

Reproducibility of in vivo electrophysiological measurements in mice.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.100840

By:

Banga, Kush;
Benson, Julius;
Bhagat, Jai;
Biderman, Dan;
Birman, Daniel;
Bonacchi, Niccolò;
Bruijns, Sebastian A.;
Buchanan, Kelly;
Campbell, Robert A. A.;
Carandini, Matteo;
Chapuis, Gaelle A.;
Churchland, Anne K.;
Davatolhagh, M. Felicia;
Hyun Dong Lee;
Faulkner, Mayo;
Gerçek, Berk;
Fei Hu;
Huntenburg, Julia;
Hurwitz, Cole Lincoln;
Khanal, Anup

Publication type:

Article

Rtf1 HMD domain facilitates global histone H2B monoubiquitination and regulates morphogenesis and virulence in the meningitis-causing pathogen Cryptococcus neoformans.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.99229

By:

Yixuan Jiang;
Ying Liang;
Fujie Zhao;
Zhenguo Lu;
Siyu Wang;
Yao Meng;
Zhanxiang Liu;
Jing Zhang;
Youbao Zhao

Publication type:

Article

Drosophila epidermal cells are intrinsically mechanosensitive and modulate nociceptive behavioral outputs.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.95379

By:

Jiro Yoshino;
Mali, Sonali S.;
Williams, Claire R.;
Takeshi Morita;
Emerson, Chloe E.;
Arp, Christopher J.;
Miller, Sophie E.;
Chang Yin;
Lydia Thé;
Chikayo Hemmi;
Mana Motoyoshi;
Kenichi Ishii;
Kazuo Emoto;
Bautista, Diana M.;
Parrish, Jay Z.

Publication type:

Article

easonally migratory songbirds have different historic population size characteristics than resident relatives.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.90848

By:

Winker, Kevin;
Delmore, Kira

Publication type:

Article

Effects of blood meal source and seasonality on reproductive traits of Culex quinquefasciatus (Diptera: Culicidae).

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.89485

By:

Rucci, Kevin Alen;
Barco, Gabriel;
Onorato, Andrea;
Beranek, Mauricio;
Pueta, Mariana;
Díaz, Adrián

Publication type:

Article

Transparency of research practices in cardiovascular literature.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.81051

By:

Heckerman, Gabriel O.;
Tzng, Eileen;
Campos-Melendez, Arely;
Ekwueme, Chisomaga;
Mueller, Adrienne

Publication type:

Article

Diversity and functional specialization of oyster immune cells uncovered by integrative single-cell level investigations.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.102622

By:

De La Forest Divonne, Sebastien;
Pouzadoux, Juliette;
Romatif, Oceane;
Montagnani, Caroline;
Mitta, Guillaume;
Destoumieux-Garzón, Delphine;
Gourbal, Benjamin;
Charriere, Guillaume M.;
Vignal, Emmanuel

Publication type:

Article

Linking O-GlcNAc and intron retention.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.107226

By:

HANOVER, JOHN A.

Publication type:

Article

HERV activation segregates ME/CFS from fibromyalgia while defining a novel nosologic entity.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104441

By:

Giménez-Orenga, Karen;
Martín-Martínez, Eva;
Nathanson, Lubov;
Oltra, Elisa

Publication type:

Article

Dynamics of striatal action selection and reinforcement learning.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101747

By:

Lindsey, Jack W.;
Markowitz, Jeffrey;
Gillis, Winthrop F.;
Datta, Sandeep R.;
Litwin-Kumar, Ashok

Publication type:

Article

Adolescent alcohol exposure promotes mechanical allodynia and alters synaptic function at inputs from the basolateral amygdala to the prelimbic cortex.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101667

By:

Obray, J. Daniel;
Wilkes, Erik T.;
Scofield, Mike;
Chandler, L. Judson

Publication type:

Article

Non-feature-specific elevated responses and feature-specific backward replay in human brain induced by visual sequence exposure.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101511

By:

Tao He;
Xizi Gong;
Qian Wang;
Xinyi Zhu;
Yunzhe Liu;
Fang Fang

Publication type:

Article

VGLL2 and TEAD1 fusion proteins identified in human sarcoma drive YAP/TAZ-independent tumorigenesis by engaging EP300.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.98386

By:

Susu Guo;
Xiaodi Hu;
Cotton, Jennifer L.;
Lifang Ma;
Qi Li;
Jiangtao Cui;
Yongjie Wang;
Thakare, Ritesh P.;
Zhipeng Tao;
Y Tony Ip;
Xu Wu;
Jiayi Wang;
Junhao Mao

Publication type:

Article

Characterisation and comparison of semen microbiota and bacterial load in men with infertility, recurrent miscarriage, or proven fertility.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.96090

By:

Mowla, Shahriar;
Farahani, Linda;
Tharakan, Tharu;
Davies, Rhianna;
Correia, Goncalo D. S.;
Lee, Yun S.;
Kundu, Samit;
Khanjani, Shirin;
Sindi, Emad;
Rai, Raj;
Regan, Lesley;
Khalifa, Dalia;
Henkel, Ralf;
Minhas, Suks;
Dhillo, Waljit S.;
Nagi, Jara Ben;
Bennett, Phillip;
MacIntyre, David A.;
Jayasena, Channa N.

Publication type:

Article

Comprehensive analysis of nasal IgA antibodies induced by intranasal administration of the SARS-CoV-2 spike protein.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.88387

By:

Kentarou Waki;
Hideki Tani;
Eigo Kawahara;
Yumiko Saga;
Takahisa Shimada;
Emiko Yamazaki;
Seiichi Koike;
Yoshitomo Morinaga;
Masaharu Isobe;
Nobuyuki Kurosawa

Publication type:

Article

MARK2 regulates Golgi apparatus reorientation by phosphorylation of CAMSAP2 in directional cell migratio.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.105977

By:

Peipei Xu;
Rui Zhang;
Zhengrong Zhou;
Honglin Xu;
Yuejia Li;
Mengge Yang;
Ruifan Lin;
Yingchun Wang;
Xiahe Huang;
Qi Xie;
Wenxiang Meng

Publication type:

Article

SIRT2-mediated ACSS2 K271 deacetylation suppresses lipogenesis under nutrient stress.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.97019

By:

Karim, Rezwana;
Teng, Wendi;
Behram, Cameron D.;
Lin, Hening

Publication type:

Article

Emergence of Dip2-mediated specific DAG-based PKC signalling axis in eukaryotes.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104011

By:

Shambhavi, Sakshi;
Mondal, Sudipta;
Chakraborty, Arnab;
Shukla, Nikita;
Panda, Bapin Kumar;
Kumar, Santhosh;
Kinatukara, Priyadarshan;
Pal, Biswajit;
Kamat, Siddhesh S.;
Sankaranarayanan, Rajan

Publication type:

Article

Anti-drift pose tracker (ADPT), a transformer-based network for robust animal pose estimation cross-species.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.95709

By:

Guoling Tang;
Yaning Han;
Xing Sun;
Ruonan Zhang;
Ming-Hu Han;
Quanying Liu;
Pengfei Wei

Publication type:

Article

Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.103615

By:

Qian Wang;
Hongge Li;
Yingyu Mao;
Garg, Ankur;
Eun Sil Park;
Yihua Wu;
Chow, Alyssa;
Peregrin, John;
Xin Zhang

Publication type:

Article

The context-dependent epigenetic and organogenesis programs determine 3D vs. 2D cellular fitness of MYC-driven murine liver cancer cells.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101299

By:

Jie Fang;
Singh, Shivendra;
Wells, Brennan;
Qiong Wu;
Hongjian Jin;
Janke, Laura J.;
Shibiao Wan;
Steele, Jacob A.;
Connelly, Jon P.;
Murphy, Andrew J.;
Ruoning Wang;
Davidoff, Andrew;
Ashcroft, Margaret;
Pruett-Miller, Shondra M.;
Jun Yang

Publication type:

Article

Reprograming gene expression in 'hibernating' C. elegans involves the IRE-1/XBP-1 pathway.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101186

By:

Engelfriet, Melanie Lianne;
Yanwu Guo;
Arnold, Andreas;
Valen, Eivind;
Ciosk, Rafal

Publication type:

Article

Differences in size and number of embryonic type II neuroblast lineages correlate with divergent timing of central complex development between beetle and fly.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.99717

By:

Rethemeier, Simon;
Fritzsche, Sonja;
Mühlen, Dominik;
Bucher, Gregor;
Hunnekuhl, Vera S.

Publication type:

Article

RAG suppresses group 2 innate lymphoid cells.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.98287

By:

Ver Heul, Aaron M.;
Mack, Madison;
Zamidar, Lydia;
Tamari, Masato;
Ting-Lin Yang;
Trier, Anna M.;
Do-Hyun Kim;
Janzen-Meza, Hannah;
Van Dyken, Steven J.;
Chyi-Song Hsieh;
Karo, Jenny M.;
Sun, Joseph C.;
Kim, Brian S.

Publication type:

Article

Quantifying feral pig interactions to inform disease transmission networks.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.102643

By:

Tatiana Proboste, Tatiana;
Turnlund, Abigail;
Bengsen, Andrew;
Gentle, Matthew;
Wilson, Cameron;
Harriott, Lana;
Fuller, Richard A.;
Marshall, Darren

Publication type:

Article

Not all dimers are equal: Disease-causing mutations in the signaling protein BMP4 impair its secretion, but only when it is made as a homodimer.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.105018

By:

PATEL, JEET H.;
MULLINS, MARY C.

Publication type:

Article

Disruption of the novel nested gene Aff3ir mediates disturbed flow-induced atherosclerosis in mice.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.103413

By:

Shuo He;
Lei Huang;
Zhuozheng Chen;
Ze Yuan;
Yue Zhao;
Lingfang Zeng;
Yi Zhu;
Jinlong He

Publication type:

Article