Works matching IS 2050-084X AND DT 2025

Results: 839

The myeloid cell-driven transdifferentiation of endothelial cells into pericytes promotes the restoration of BBB function and brain self-repair after stroke.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.105593

By:

Tingbo Li;
Ling Yang;
Jiaqi Tu;
Yufan Hao;
Zhu Zhu;
Yingjie Xiong;
Qingzhu Gao;
Lili Zhou;
Guanglei Xie;
Dongdong Zhang;
Xuzhao Li;
Yuxiao Jin;
Yiyi Zhang;
Bingrui Zhao;
Nan Li;
Xi Wang;
Jie-Min Jia

Publication type:

Article

Cryo-EM structures of a pentameric ligand-gated ion channel in liposomes.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.106728

By:

Dalal, Vikram;
Tan, Brandon K.;
Xu, Hanrui;
Cheng, Wayland W. L.

Publication type:

Article

Therapeutic effects of PDGF-AB/BB against cellular senescence in human intervertebral disc.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.103073

By:

Changli Zhang;
Diaz-Hernandez, Martha Elena;
Fukunaga, Takanori;
Shenoy, Sreekala;
Tim Yoon, Sangwook;
Haglund, Lisbet;
Drissi, Hicham

Publication type:

Article

Physical constraints and biological regulations underlie universal osmoresponses.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.102858

By:

Yiyang Ye;
Qirun Wang;
Jie Lin

Publication type:

Article

Single neurons and networks in the mouse claustrum integrate input from widespread cortical sources.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.98002

By:

Shelton, Andrew M.;
Oliver, David K.;
Lazarte, Ivan P.;
Grimstvedt, Joachim S.;
Kapoor, Ishaan;
Swann, Jake A.;
Ashcroft, Caitlin A.;
Williams, Simon N.;
Conway, Niall;
Tir, Selma;
Robinson, Amy;
Peirson, Stuart;
Akam, Thomas;
Kentros, Clifford G.;
Witter, Menno P.;
Butt, Simon J. B.;
Packer, Adam Max

Publication type:

Article

Structure of human PIEZO1 and its slow-inactivating channelopathy mutants.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101923

By:

Yuanyue Shan;
Xinyi Guo;
Mengmeng Zhang;
Meiyu Chen;
Ying Li;
Mingfeng Zhang;
Duanqing Pei

Publication type:

Article

Heron, a Knowledge Graph editor for intuitive implementation of Python-based experimental pipelines.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.91915

By:

Dimitriadis, George;
Svahn, Ella;
MacAskill, Andrew F.;
Akrami, Athena

Publication type:

Article

Embracing the complexity of cooperation.

Published in:: eLife, 2025, p. 1, doi. 10.7554/eLife.108039
Publication type:: Article

Differential roles of NaV1.2 and NaV1.6 in neocortical pyramidal cell excitability.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.105696

By:

Garcia, Joshua D.;
Chenyu Wang;
Alexander, Ryan P. D.;
Banks, Emmie;
Fenton, Timothy;
DeKeyser, Jean-Marc;
Abramova, Tatiana V.;
George, Alfred L.;
Ben-Shalom, Roy;
Hackos, David H.;
Bender, Kevin J.

Publication type:

Article

Old age variably impacts chimpanzee engagement and efficiency in stone tool use.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.105411

By:

Howard-Spink, Elliot;
Matsuzawa, Tetsuro;
Carvalho, Susana;
Hobaiter, Catherine;
Almeida-Warren, Katarina;
Gruber, Thibaud;
Biro, Dora

Publication type:

Article

Opposing regulation of TNF responses by IFN-γ and a PGE2-cAMP axis that is apparent in rheumatoid and immune checkpoint inhibitor-induced arthritis human IL-1β+ macrophages.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104367

By:

Sokhi, Upneet K.;
Ruoxi Yuan;
Mishra, Bikash;
Chinenov, Yurii;
Singaraju, Anvita;
Chan, Karmela K.;
Bass, Anne;
Bell, Richard D.;
Donlin, Laura;
Ivashkiv, Lionel B.

Publication type:

Article

Human formin FHOD3-mediated actin elongation is required for sarcomere integrity in cardiomyocytes.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104048

By:

Valencia, Dylan A.;
Koeberlein, Angela N.;
Nakano, Haruko;
Rudas, Akos;
Patel, Aanand A.;
Harui, Airi;
Spencer, Cassandra;
Nakano, Atsushi;
Quinlan, Margot E.

Publication type:

Article

Female-germline specific protein Sakura interacts with Otu and is crucial for germline stem cell renewal and differentiation and oogenesis.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.103828

By:

Azlan, Azali;
Li Zhu;
Ryuya Fukunaga

Publication type:

Article

Malnutrition drives infection susceptibility and dysregulated myelopoiesis that persists after refeeding intervention.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101670

By:

Sukhina, Alisa;
Queriault, Clemence;
Roy, Saptarshi;
Hall, Elise;
Rome, Kelly;
Aggarwal, Muskaan;
Nunn, Elizabeth;
Weiss, Ashley;
Nguyen, Janet;
Bennett, F. Chris;
Bailis, Will

Publication type:

Article

A mathematical model for ketosis-prone diabetes suggests the existence of multiple pancreatic β-cell inactivation mechanisms.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.100193

By:

Ridout, Sean A.;
Vellanki, Priyathama;
Nemenman, Ilya

Publication type:

Article

EPHA4 signaling dysregulation links abnormal locomotion and the development of idiopathic scoliosis.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.95324

By:

Lianlei Wang;
Xinyu Yang;
Sen Zhao;
Pengfei Zheng;
Wen Wen;
Kexin Xu;
Xi Cheng;
Qing Li;
Khanshour, Anas M.;
Yoshinao Koike;
Junjun Liu;
Xin Fan;
Nao Otomo;
Zefu Chen;
Yaqi Li;
Lulu Li;
Haibo Xie;
Panpan Zhu;
Xiaoxin Li;
Yuchen Niu

Publication type:

Article

Polyphosphate discriminates protein conformational ensembles more efficiently than DNA promoting diverse assembly and maturation behaviors.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.105461

By:

Goyal, Saloni;
Rajendran, Divya;
Mani, Anup Kumar;
Naganathan, Athi N.

Publication type:

Article

Harnessing AlphaFold to reveal hERG channel conformational state secrets.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104901

By:

Khoa Ngo;
Pei-Chi Yang;
Yarov-Yarovoy, Vladimir;
Clancy, Colleen E.;
Vorobyov, Igor

Publication type:

Article

PRDM16 functions as a co-repressor in the BMP pathway to suppress neural stem cell proliferation.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104076

By:

Li He;
Jiayu Wen;
Qi Dai

Publication type:

Article

Self-other generalisation shapes social interaction and is disrupted in borderline personality disorder.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104008

By:

Barnby, Joseph M.;
Nguyen, Jen;
Griem, Julia;
Wloszek, Magdalena;
Burgess, Henry;
Richards, Linda J.;
Kingston, Jessica;
Cooper, Gavin;
Montague, P. Read;
Dayan, Peter;
Nolte, Tobias;
Fonagy, Peter

Publication type:

Article

S100a4+ alveolar macrophages accelerate the progression of precancerous atypical adenomatous hyperplasia by promoting the angiogenic function regulated by fatty acid metabolism.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101731

By:

Hong Huang;
Ying Yang;
Qiuju Zhang;
Yongfeng Yang;
Zhenqi Xiong;
Shengqiang Mao;
Tingting Song;
Yilong Wang;
Zhiqiang Liu;
Hong Bu;
Li Zhang;
Le Zhang

Publication type:

Article

Normative evidence weighing and accumulation in correlated environments.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.100258

By:

Tardiff, Nathan;
Jiwon Kang;
Gold, Joshua I.

Publication type:

Article

Ultraslow serotonin oscillations in the hippocampus delineate substates across NREM and waking.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101105

By:

Cooper, Claire;
Parthier, Daniel;
Sibille, Jeremie;
Tukker, John J.;
Tritsch, Nicolas;
Schmitz, Dietmar

Publication type:

Article

Acquisition of auditory discrimination mediated by different processes through two distinct circuits linked to the lateral striatum.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.97326

By:

Setogawa, Susumu;
Okauchi, Takashi;
Di Hu;
Yasuhiro Wada;
Keigo Hikishima;
Hirotaka Onoe;
Kayo Nishizawa;
Nobuyuki Sakayori;
Hiroyuki Miyawaki;
Takuma Kitanishi;
Kenji Mizuseki;
Yilong Cui;
Kazuto Kobayashi

Publication type:

Article

The microbiome interacts with the circadian clock and dietary composition to regulate metabolite cycling in the Drosophila gut.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.97130

By:

Yueliang Zhang;
Noya, Sara B.;
Yongjun Li;
Jichao Fang;
Sehgal, Amita

Publication type:

Article

Aiming for spatial and temporal control of gene expression.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.107945

By:

IGOR TRAVISANO, STANISLAO;
CHING-LING LIEN

Publication type:

Article

NR2F2 is required in the embryonic testis for fetal Leydig cell development.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.103783

By:

Perea-Gomez, Aitana;
Bellido Carreras, Natividad;
Dhellemmes, Magali;
Furong Tang;
Le Gallo, Coralie;
Chaboissier, Marie-Christine

Publication type:

Article

Bacteriophage infection drives loss of β-lactam resistance in methicillin-resistant Staphylococcus aureus.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.102743

By:

My Tran;
Hernandez Viera, Angel J.;
Tran, Patricia Q.;
Nilsen, Erick D.;
Tran, Lily;
Mo, Charlie Y.

Publication type:

Article

The magnitude and time course of pre-saccadic foveal prediction depend on the conspicuity of the saccade target.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.91236

By:

Kroell, Lisa M.;
Rolfs, Martin

Publication type:

Article

CRISPR-edited DPSCs constitutively expressing BDNF enhance dentin regeneration in injured teeth.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.105153

By:

Ji Hyun Kim;
Irfan, Muhammad;
Sreekumar, Sreelekshmi;
Phimon, Atsawasuwan;
Kim, Stephanie;
Seung Chung

Publication type:

Article

Molecular characterization of gustatory second-order neurons reveals integrative mechanisms of gustatory and metabolic information.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.100947

By:

Mollá-Albaladejo, Rubén;
Jiménez-Caballero, Manuel;
Sanchez-Alcaniz, Juan Antonio

Publication type:

Article

Prebiotic gas flow environment enables isothermal nucleic acid replication.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.100152

By:

Schwintek, Philipp;
Eren, Emre;
Bernhard Mast, Christof;
Braun, Dieter

Publication type:

Article

A temporally restricted function of the dopamine receptor Dop1R2 during memory formation.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.99368

By:

Kaldun, Jenifer C.;
Calia, Emanuele;
Bangalore Mukunda, Ganesh Chinmai;
Fritsch, Cornelia;
Komarov, Nikita;
Sprecher, Simon G.

Publication type:

Article

Fast evolution of SOS-independent multi-drug resistance in bacteria.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.95058

By:

Le Zhang;
Yunpeng Guan;
YuenYee Cheng;
Cokcetin, Nural N.;
Bottomley, Amy L.;
Robinson, Andrew;
Harry, Elizabeth J.;
van Oijen, Antoine M.;
Qian Peter Su;
Dayong Jin

Publication type:

Article

Returning aging cells to productivity.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.103073

By:

VAIDYA, RACHANA W.;
TANG, SIMON Y.

Publication type:

Article

Forward genetics in C. elegans reveals genetic adaptations to polyunsaturated fatty acid deficiency.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104181

By:

Kaper, Delaney;
Radović, Uroš;
Bergh, Per-Olof;
Qvist, August;
Henricsson, Marcus;
Borén, Jan;
Pilon, Marc

Publication type:

Article

Function and firing of the Streptomyces coelicolor contractile injection system requires the membrane protein CisA.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104064

By:

Casu, Bastien;
Sallmen, Joseph W.;
Haas, Peter E.;
Chandra, Govind;
Afanasyev, Pavel;
Jingwei Xu;
Pilhofer, Martin;
Schlimpert, Susan

Publication type:

Article

Humans adapt rationally to approximate estimates of uncertainty.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.103734

By:

Pulcu, Erdem;
Browning, Michael

Publication type:

Article

β-Glucan reprograms alveolar macrophages via neutrophil/IFNγ axis in a murine model of lung injury.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.102068

By:

Prevel, Renaud;
Pernet, Erwan;
Kim A. Tran;
Sadek, Abderrahmane;
Sadeghi, Mina;
Lapshina, Elizabeth;
Jurado, Leonardo F.;
Kristof, Arnold S.;
Moumni, Mohieddine;
Poschmann, Jeremie;
Divangahi, Maziar

Publication type:

Article

Unraveling CRP/cAMP-mediated metabolic regulation in Escherichia coli persister cells.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.99735

By:

Han G. Ngo;
Mohiuddin, Sayed Golam;
Ananda, Aina;
Orman, Mehmet

Publication type:

Article

Quantitative intra- Golgi transport and organization data suggest the stable compartment nature of the Golgi.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.98582

By:

Hieng Chiong Tie;
Haiyun Wang;
Mahajan, Divyanshu;
Yuen In Lam, Hilbert;
Xiuping Sun;
Bing Chen;
Yuguang Mu;
Lei Lu

Publication type:

Article

Diverse prey capture strategies in teleost larvae.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.98347

By:

Mearns, Duncan S.;
Hunt, Sydney A.;
Schneider, Martin W.;
Parker, Ash V.;
Stemmer, Manuel;
Baier, Herwig

Publication type:

Article

Heat stress induces phage tolerance in Enterobacteriaceae.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.105703

By:

Fan Zhang;
Hao-Ze Chen;
Bo Zheng;
Liang Huang;
Ye Xiang;
Jing-Ren Zhang;
Jia-Feng Liu

Publication type:

Article

The C-terminus of the multi-drug efflux pump EmrE prevents proton leak by gating transport.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.105525

By:

Brousseau, Merissa;
Da Teng;
Thomas, Nathan E.;
Voth, Gregory A.;
Henzler-Wildman, Katherine A.

Publication type:

Article

Magnetically steered cell therapy for reduction of intraocular pressure as a treatment strategy for open-angle glaucoma.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.103256

By:

Bahranifard, M. Reza;
Chan, Jessica;
Read, A. Thomas;
Guorong Li;
Lin Cheng;
Safa, Babak N.;
Siadat, Seyed Mohammad;
Jhunjhunwala, Anamik;
Grossniklaus, Hans E.;
Emelianov, Stanislav Y.;
Stamer, W. Daniel;
Kuehn, Markus H.;
Ethier, C. Ross

Publication type:

Article

The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.101984

By:

Fan Zhang;
Yuan Wang;
Luyang Zhang;
Chunjie Wang;
Deping Chen;
Haibo Liu;
Ren Xu;
Haynes, Cole M.;
Jae-Hyuck Shim;
Xianpeng Ge

Publication type:

Article

The molecular logic of Gtr1/2- and Pib2-dependent TORC1 regulation in budding yeast.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.94628

By:

Cecil, Jacob H.;
Padilla, Cristina M.;
Lipinski, Austin A.;
Langlais, Paul;
Xiangxia Luo;
Capaldi, Andrew P.

Publication type:

Article

Highly sensitive in vivo detection of dynamic changes in enkephalins following acute stress in mice.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.91609

By:

Mikati, Marwa O.;
Erdmann-Gilmore, Petra;
Connors, Rose;
Conway, Sineadh M.;
Malone, Jim;
Woods, Justin;
Sprung, Robert W.;
Townsend, Reid R.;
Al-Hasani, Ream

Publication type:

Article

Drosophila hamlet mediates epithelial tissue assembly of the reproductive system.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104164

By:

Huazhen Wang;
Bertonnier-Brouty, Ludivine;
Artner, Isabella;
Jiayu Wen;
Qi Dai

Publication type:

Article

Multifaceted role of galanin in brain excitability.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.98634

By:

Rieser, Nicolas N.;
Ronchetti, Milena;
Lea Hotz, Adriana Lea;
Neuhauss, Stephan C. F.

Publication type:

Article