Works matching IS 2050-084X AND DT 2019

Results: 358

Releasing a preprint is associated with more attention and citations for the peer-reviewed article.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.52646

By:

FU, DARWIN Y.;
HUGHEY, JACOB J.

Publication type:

Article

Uncovering the secret life of Rho GTPases: New methods to directly visualize Rho GTPases reveal how a protein called RhoGDI regulates the activity of these 'molecular switches' at the plasma membrane.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.53276

By:

PERRY, JENNA A.;
SHAUB MADDOX, AMY

Publication type:

Article

Fly model sheds light on brain disease: Experiments on flies suggest that a gain-of-function mechanism in a protein called CSPα contributes to the progressive brain disease CLN4.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.53233

By:

BERRYER, MARTIN H.;
KOSMACZEWSKI, SARA G.;
BARRETT, LINDY E.

Publication type:

Article

Cycling in synchrony: The corn smut fungus uses two different mechanisms to control its cell cycle when it is infecting plants.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.52884

By:

OSÉS-RUIZ, MÍRIAM;
TALBOT, NICHOLAS J.

Publication type:

Article

Searching for solutions to the missing heritability problem: Rare genetic variants in yeast explain a large amount of phenotypic variation in a complex trait like growth.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.53018

By:

PALLARES, LUISA F.

Publication type:

Article

Rethinking research into metastasis: The partial success of an attempt to repeat findings in cancer biology highlights the need to improve study designs for preclinical research into metastasis and the targeting of cancer cells.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.53511

By:

FRIEDL, PETER

Publication type:

Article

Modelling survival: A new mouse model of sepsis can reproduce the long-term muscle weakness seen in patients who survive this life-threatening illness.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.52959

By:

ZIMMERS, TERESA A.;
KONIARIS, LEONIDAS G.

Publication type:

Article

Down but not out: A new study in monkeys suggests that treating HIV infection early with antiretroviral therapy reduces the number of latent viruses, but has little impact on viral reactivation when treatment stops.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.53363

By:

LARRAGOITE, ERIN T.;
SPIVAK, ADAM M.

Publication type:

Article

Too hip for two sacral vertebrae: A complex pelvic morphology has been discovered in the fossils of one of the largest crocodylians.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.53399

By:

STOCKER, MICHELLE R.

Publication type:

Article

Cryo electron tomography with Volta phase plate reveals novel structural foundations of the 96-nm axonemal repeat in the pathogen Trypanosoma brucei.

Published in:

eLife, 2019, p. 1

By:

Imhof, Simon;
Jiayan Zhang;
Hui Wang;
Khanh Huy Bui;
Hoangkim Nguyen;
Atanasov, Ivo;
Hui, Wong H.;
Shun Kai Yang;
Zhou, Z. Hong;
Hill, Kent L.

Publication type:

Article

Interhemispherically dynamic representation of an eye movement-related activity in mouse frontal cortex.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.50855

By:

Sato, Takashi R.;
Takahide Itokazu;
Hironobu Osaki;
Makoto Ohtake;
Tetsuya Yamamoto;
Kazuhiro Sohya;
Takakuni Maki;
Sato, Tatsuo K.

Publication type:

Article

An N-terminal motif in NLR immune receptors is functionally conserved across distantly related plant species.

Published in:

eLife, 2019, p. 1

By:

Hiroaki Adachi;
Contreras, Mauricio;
Harant, Adeline;
Chih-hang Wu;
Derevnina, Lida;
Toshiyuki Sakai;
Duggan, Cian;
Moratto, Eleonora;
Bozkurt, Tolga O.;
Maqbool, Abbas;
Win, Joe;
Kamoun, Sophien

Publication type:

Article

Local axonal morphology guides the topography of interneuron myelination in mouse and human neocortex.

Published in:

eLife, 2019, p. 1

By:

Stedehouder, J.;
Brizee, D.;
Slotman, J. A.;
Pascual-García, M.;
Leyrer, M. L.;
Bouwen, B. L. J.;
Dirven, C. M. F.;
Gao, Z.;
Berson, D. M.;
Houtsmuller, A. B.;
Kushner, S. A.

Publication type:

Article

Structure of a mitochondrial ATP synthase with bound native cardiolipin.

Published in:

eLife, 2019, p. 1

By:

Mühleip, Alexander;
McComas, Sarah E.;
Amunts, A.

Publication type:

Article

Cycles of autoubiquitination and deubiquitination regulate the ERAD ubiquitin ligase Hrd1.

Published in:

eLife, 2019, p. 1

By:

Peterson, Brian G.;
Glaser, Morgan L.;
Rapoport, Tom A.;
Baldridge, Ryan D.

Publication type:

Article

Drosophila PSI controls circadian period and the phase of circadian behavior under temperature cycle via tim splicing.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.50063

By:

Foley, Lauren E.;
Jinli Ling;
Joshi, Radhika;
Evantal, Naveh;
Kadener, Sebastian;
Emery, Patrick

Publication type:

Article

Design of biochemical pattern forming systems from minimal motifs.

Published in:

eLife, 2019, p. 1

By:

Glock, Philipp;
Brauns, Fridtjof;
Halatek, Jacob;
Frey, Erwin;
Schwille, Petra

Publication type:

Article

Systematic genetic analysis of the MHC region reveals mechanistic underpinnings of HLA type associations with disease.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.48476

By:

D'Antonio, Matteo;
Reyna, Joaquin;
Jakubosky, David;
Donovan, Margaret K. R.;
Bonder, Marc-Jan;
Hiroko Matsui;
Stegle, Oliver;
Naoki Nariai;
D'Antonio-Chronowska, Agnieszka;
Frazer, Kelly A.

Publication type:

Article

Atypical memory B-cells are associated with Plasmodium falciparum anemia through anti-phosphatidylserine antibodies.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.48309

By:

Rivera-Correa, Juan;
Mackroth, Maria Sophia;
Jacobs, Thomas;
zur Wiesch, Julian Schulze;
Rolling, Thierry;
Rodriguez, Ana

Publication type:

Article

Elevating acetyl-CoA levels reduces aspects of brain aging.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.47866

By:

Currais, Antonio;
Ling Huang;
Goldberg, Joshua;
Petrascheck, Michael;
Ates, Gamze;
Pinto-Duarte, António;
Shokhirev, Maxim N.;
Schubert, David;
Maher, Pamela

Publication type:

Article

Helix breaking transition in the S4 of HCN channel is critical for hyperpolarization-dependent gating.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.53400

By:

Kasimova, Marina A.;
Tewari, Debanjan;
Cowgill, John B.;
Ursuleaz, Willy Carrasquel;
Lin, Jenna L.;
Delemotte, Lucie;
Chanda, Baron

Publication type:

Article

Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.50319

By:

Yue Qu;
Hahn, Ines;
Lees, Meredith;
Parkin, Jill;
Voelzmann, André;
Dorey, Karel;
Rathbone, Alex;
Friel, Claire T.;
Allan, Victoria J.;
Okenve-Ramos, Pilar;
Sanchez-Soriano, Natalia;
Prokop, Andreas

Publication type:

Article

Asymmetrical diversification of the receptor-ligand interaction controlling self-incompatibility in Arabidopsis.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.50253

By:

Chantreau, Maxime;
Poux, Céline;
Lensink, Marc F.;
Brysbaert, Guillaume;
Vekemans, Xavier;
Castric, Vincent

Publication type:

Article

Chromosome territory formation attenuates the translocation potential of cells.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.49553

By:

Rosin, Leah F.;
Crocker, Olivia;
Isenhart, Randi L.;
Nguyen, Son C.;
Zhuxuan Xu;
Joyce, Eric F.

Publication type:

Article

Stimulating the hippocampal posterior-medial network enhances task-dependent connectivity and memory.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.49458

By:

Warren, Kristen N.;
Hermiller, Molly S.;
Nilakantan, Aneesha S.;
Voss, Joel L.

Publication type:

Article

Dopamine neuron ensembles signal the content of sensory prediction errors.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.49315

By:

Stalnaker, Thomas A.;
Howard, James D.;
Takahashi, Yuji K.;
Gershman, Samuel J.;
Kahnt, Thorsten;
Schoenbaum, Geoffrey

Publication type:

Article

Kinetics of cytokine receptor trafficking determine signaling and functional selectivity.

Published in:

eLife, 2019, p. 1

By:

J., Martinez-Fabregas;
S., Wilmes;
L., Wang;
M., Hafer;
E., Pohler;
J., Lokau;
C., Garbers;
A., Cozzani;
J., Piehler;
M., Kazemian;
S., Mitra;
I., Moraga

Publication type:

Article

Cyclin-dependent kinase 5 (CDK5) regulates the circadian clock.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.50925

By:

Brenna, Andrea;
Olejniczak, Iwona;
Chavan, Rohit;
Ripperger, Jürgen A.;
Langmesser, Sonja;
Cameroni, Elisabetta;
Zehan Hu;
De Virgilio, Claudio;
Dengjel, Jörn;
Albrecht, Urs

Publication type:

Article

Combinatorial chromatin dynamics foster accurate cardiopharyngeal fate choices.

Published in:

eLife, 2019, p. 1

By:

Racioppi, Claudia;
Wiechecki, Keira A.;
Christiaen, Lionel

Publication type:

Article

Differential impact of self and environmental antigens on the ontogeny and maintenance of CD4<sup>+</sup> T cell memory.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.48901

By:

Hogan, Thea;
Nowicka, Maria;
Cownden, Daniel;
Pearson, Claire F.;
Yates, Andrew J.;
Seddon, Benedict

Publication type:

Article

Free circular introns with an unusual branchpoint in neuronal projections.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.47809

By:

Saini, Harleen;
Bicknell, Alicia A.;
Eddy, Sean R.;
Moore, Melissa J.

Publication type:

Article

Dichotomous organization of amygdala/temporal-prefrontal bundles in both humans and monkeys.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.47175

By:

Folloni, Davide;
Sallet, Jerome;
Khrapitchev, Alexandre A.;
Sibson, Nicola;
Verhagen, Lennart;
Mars, Rogier B.

Publication type:

Article

Thermosensitive alternative splicing senses and mediates temperature adaptation in Drosophila.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.44642

By:

Anduaga, Ane Martin;
Evantal, Naveh;
Patop, Ines Lucia;
Bartok, Osnat;
Weiss, Ron;
Kadener, Sebastian

Publication type:

Article

Movement of accessible plasma membrane cholesterol by the GRAMD1 lipid transfer protein complex.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.51401

By:

Tomoki Naito;
Ercan, Bilge;
Krshnan, Logesvaran;
Triebl, Alexander;
Hong Zheng Koh, Dylan;
Fan-Yan Wei;
Kazuhito Tomizawa;
Torta, Federico Tesio;
Wenk, Markus R.;
Yasunori Saheki

Publication type:

Article

The HCN domain couples voltage gating and cAMP response in hyperpolarization-activated cyclic nucleotide-gated channels.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.49672

By:

Porro, Alessandro;
Saponaro, Andrea;
Gasparri, Federica;
Bauer, Daniel;
Gross, Christine;
Pisoni, Matteo;
Abbandonato, Gerardo;
Hamacher, Kay;
Santoro, Bina;
Thiel, Gerhard;
Moroni, Anna

Publication type:

Article

Brain clusterin protein isoforms and mitochondrial localization.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.48255

By:

Herring, Sarah K.;
Hee-Jung Moon;
Rawal, Punam;
Chhibber, Anindit;
Liqin Zhao

Publication type:

Article

Screening identifies small molecules that enhance the maturation of human pluripotent stem cell-derived myotubes.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.47970

By:

Selvaraj, Sridhar;
Mondragon-Gonzalez, Ricardo;
Bin Xu;
Magli, Alessandro;
Hyunkee Kim;
Lainé, Jeanne;
Kiley, James;
Mckee, Holly;
Rinaldi, Fabrizio;
Aho, Joy;
Tabti, Nacira;
Wei Shen;
Perlingeiro, Rita C. R.

Publication type:

Article

Formation of a β-barrel membrane protein is catalyzed by the interior surface of the assembly machine protein BamA.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.49787

By:

Lee, James;
Tomasek, David;
Santos, Thiago M. A.;
May, Mary D.;
Meuskens, Ina;
Kahne, Daniel

Publication type:

Article

Evolutionarily conserved long-chain Acyl-CoA synthetases regulate membrane composition and fluidity.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.47733

By:

Ruiz, Mario;
Bodhicharla, Rakesh;
Ståhlman, Marcus;
Svensk, Emma;
Busayavalasa, Kiran;
Palmgren, Henrik;
Ruhanen, Hanna;
Boren, Jan;
Pilon, Marc

Publication type:

Article

An image-computable model for the stimulus selectivity of gamma oscillations.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.47035

By:

Hermes, Dora;
Petridou, Natalia;
Kay, Kendrick N.;
Winawer, Jonathan

Publication type:

Article

Modular transcriptional programs separately define axon and dendrite connectivity.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.50822

By:

Kurmangaliyev, Yerbol Z.;
Juyoun Yoo;
LoCascio, Samuel A.;
Zipursky, S. Lawrence

Publication type:

Article

DNA damage checkpoint activation impairs chromatin homeostasis and promotes mitotic catastrophe during aging.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.50778

By:

Crane, Matthew M.;
Russell, Adam E.;
Schafer, Brent J.;
Blue, Ben W.;
Whalen, Riley;
Almazan, Jared;
Mung Gi Hong;
Bao Nguyen;
Goings, Joslyn E.;
Chen, Kenneth L.;
Kelly, Ryan;
Kaeberlein, Matt

Publication type:

Article

Mechanisms of hyperexcitability in Alzheimer's disease hiPSC-derived neurons and cerebral organoids vs isogenic controls.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.50333

By:

Ghatak, Swagata;
Dolatabadi, Nima;
Trudler, Dorit;
XiaoTong Zhang;
Yin Wu;
Mohata, Madhav;
Ambasudhan, Rajesh;
Talantova, Maria;
Lipton, Stuart A.

Publication type:

Article

Demographic reconstruction from ancient DNA supports rapid extinction of the great auk.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.47509

By:

Thomas, Jessica E.;
Carvalho, Gary R.;
Haile, James;
Rawlence, Nicolas J.;
Martin, Michael D.;
Ho, Simon Y. W.;
Sigfússon, Arnór Þ.;
Jósefsson, Vigfús A.;
Frederiksen, Morten;
Linnebjerg, Jannie F.;
Castruita, Jose A. Samaniego;
Niemann, Jonas;
Sinding, Mikkel-Holger S.;
Sandoval-Velasco, Marcela;
Soares, André E. R.;
Lacy, Robert;
Barilaro, Christina;
Best, Juila;
Brandis, Dirk;
Cavallo, Chiara

Publication type:

Article

Multistability and regime shifts in microbial communities explained by competition for essential nutrients.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.49720

By:

Dubinkina, Veronika;
Fridman, Yulia;
Pandey, Parth Pratim;
Maslov, Sergei

Publication type:

Article

Ten simple rules for the computational modeling of behavioral data.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.49547

By:

Wilson, Robert C.;
Collins, Anne G. E.

Publication type:

Article

Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.48828

By:

Yilin Kang;
Anderson, Alexander J.;
Jackson, Thomas Daniel;
Palmer, Catherine S.;
De Souza, David P.;
Fujihara, Kenji M.;
Stait, Tegan;
Frazier, Ann E.;
Clemons, Nicholas J.;
Tull, Deidreia;
Thorburn, David R.;
McConville, Malcolm J.;
Ryan, Michael T.;
Stroud, David A.;
Stojanovski, Diana

Publication type:

Article

Single-cell transcriptomic evidence for dense intracortical neuropeptide networks.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.47889

By:

Smith, Stephen J.;
Sümbül, Uygar;
Graybuck, Lucas T.;
Collman, Forrest;
Seshamani, Sharmishtaa;
Gala, Rohan;
Gliko, Olga;
Elabbady, Leila;
Miller, Jeremy A.;
Bakken, Trygve E.;
Rossier, Jean;
Zizhen Yao;
Lein, Ed;
Hongkui Zeng;
Tasic, Bosiljka;
Hawrylycz, Michael

Publication type:

Article

Selection on mutators is not frequency-dependent.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.51177

By:

Raynes, Yevgeniy;
Weinreich, Daniel

Publication type:

Article

Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons.

Published in:

eLife, 2019, p. 1, doi. 10.7554/eLife.48718

By:

Koppers, Max;
Cagnetta, Roberta;
Toshiaki Shigeoka;
Wunderlich, Lucia C. S.;
Vallejo-Ramirez, Pedro;
Qiaojin Lin, Julie;
Sixian Zhao;
Jakobs, Maximilian A. H.;
Dwivedy, Asha;
Minett, Michael S.;
Bellon, Anaïs;
Kaminski, Clemens F.;
Harris, William A.;
Flanagan, John G.;
Holt, Christine E.

Publication type:

Article