Works matching IS 20479158 AND DT 2021 AND VI 10 AND IP 1

Results: 53

Novel multivalent design of a monoclonal antibody improves binding strength to soluble aggregates of amyloid beta.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00258-x

By:

Rofo, Fadi;
Buijs, Jos;
Falk, Ronny;
Honek, Ken;
Lannfelt, Lars;
Lilja, Anna M.;
Metzendorf, Nicole G.;
Gustavsson, Tobias;
Sehlin, Dag;
Söderberg, Linda;
Hultqvist, Greta

Publication type:

Article

Dense core vesicle markers in CSF and cortical tissues of patients with Alzheimer's disease.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00263-0

By:

Barranco, Neus;
Plá, Virginia;
Alcolea, Daniel;
Sánchez-Domínguez, Irene;
Fischer-Colbrie, Reiner;
Ferrer, Isidro;
Lleó, Alberto;
Aguado, Fernando

Publication type:

Article

Multi-mechanical waves against Alzheimer's disease pathology: a systematic review.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00256-z

By:

Monteiro, Francisca;
Sotiropoulos, Ioannis;
Carvalho, Óscar;
Sousa, Nuno;
Silva, Filipe S.

Publication type:

Article

Disruption of the white matter structural network and its correlation with baseline progression rate in patients with sporadic amyotrophic lateral sclerosis.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00255-0

By:

Li, Wenbin;
Wei, Qianqian;
Hou, Yanbing;
Lei, Du;
Ai, Yuan;
Qin, Kun;
Yang, Jing;
Kemp, Graham J.;
Shang, Huifang;
Gong, Qiyong

Publication type:

Article

NMDAR-dependent somatic potentiation of synaptic inputs is correlated with β amyloid-mediated neuronal hyperactivity.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00260-3

By:

Bao, Yifei;
Yang, Xin;
Fu, Yi;
Li, Zhengyan;
Gong, Ru;
Lu, Wei

Publication type:

Article

Mitochondrial links between brain aging and Alzheimer's disease.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00261-2

By:

Wilkins, Heather M.;
Swerdlow, Russell H.

Publication type:

Article

Predictability of polygenic risk score for progression to dementia and its interaction with APOE ε4 in mild cognitive impairment.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00259-w

By:

Pyun, Jung-Min;
Park, Young Ho;
Lee, Keon-Joo;
Kim, SangYun;
Saykin, Andrew J.;
Nho, Kwangsik

Publication type:

Article

Neurofilament light and heterogeneity of disease progression in amyotrophic lateral sclerosis: development and validation of a prediction model to improve interventional trials.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00257-y

By:

Witzel, Simon;
Frauhammer, Felix;
Steinacker, Petra;
Devos, David;
Pradat, Pierre-François;
Meininger, Vincent;
Halbgebauer, Steffen;
Oeckl, Patrick;
Schuster, Joachim;
Anders, Simon;
Dorst, Johannes;
Otto, Markus;
Ludolph, Albert C.

Publication type:

Article

Roles of physical exercise in neurodegeneration: reversal of epigenetic clock.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00254-1

By:

Xu, Miao;
Zhu, JiaYi;
Liu, Xian-Dong;
Luo, Ming-Ying;
Xu, Nan-Jie

Publication type:

Article

A perspective on therapies for amyotrophic lateral sclerosis: can disease progression be curbed?

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00250-5

By:

Xu, Xiaojiao;
Shen, Dingding;
Gao, Yining;
Zhou, Qinming;
Ni, You;
Meng, Huanyu;
Shi, Hongqin;
Le, Weidong;
Chen, Shengdi;
Chen, Sheng

Publication type:

Article

The Gold Coast criteria increases the diagnostic sensitivity for amyotrophic lateral sclerosis in a Chinese population.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00253-2

By:

Shen, Dongchao;
Yang, Xunzhe;
Wang, Yanying;
He, Di;
Sun, Xiaohan;
Cai, Zhengyi;
Li, Jinyue;
Liu, Mingsheng;
Cui, Liying

Publication type:

Article

Optimization of cerebral organoids: a more qualified model for Alzheimer's disease research.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00252-3

By:

Bi, Feng-Chen;
Yang, Xin-He;
Cheng, Xiao-Yu;
Deng, Wen-Bin;
Guo, Xiao-Li;
Yang, Hui;
Wang, Yin;
Li, Juan;
Yao, Yao

Publication type:

Article

Multivariable clinical-genetic model for predicting dyskinesia in early-onset Parkinson's disease.

Published in:

2021

By:

Chen, Yong-Ping;
Ou, Ru-Wei;
Gu, Xiao-Jing;
Zhang, Ling-Yu;
Cao, Bei;
Hou, Yan-Bing;
Liu, Kun-Cheng;
Lin, Jun-Yu;
Wei, Qian-Qian;
Zhao, Bi;
Wu, Ying;
Shang, Hui-Fang

Publication type:

Letter

Several miRNAs derived from serum extracellular vesicles are potential biomarkers for early diagnosis and progression of Parkinson's disease.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00249-y

By:

He, Shulei;
Huang, Lu;
Shao, Ci;
Nie, Tiejian;
Xia, Li;
Cui, Bozhou;
Lu, Fangfang;
Zhu, Lin;
Chen, Bolin;
Yang, Qian

Publication type:

Article

Language training for oral and written naming impairment in primary progressive aphasia: a review.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00248-z

By:

Pagnoni, Ilaria;
Gobbi, Elena;
Premi, Enrico;
Borroni, Barbara;
Binetti, Giuliano;
Cotelli, Maria;
Manenti, Rosa

Publication type:

Article

The effects of transcranial direct current stimulation on gait in patients with Parkinson's disease: a systematic review.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00245-2

By:

Pol, Fateme;
Salehinejad, Mohammad Ali;
Baharlouei, Hamzeh;
Nitsche, Michael A.

Publication type:

Article

Metabolic changes in an animal model of amyotrophic lateral sclerosis evaluated by [18F]-FDG positron emission tomography.

Published in:

2021

By:

Giacobbo, Bruno Lima;
Mediavilla, Tomás;
Marcellino, Daniel J.;
Sultan, Fahad

Publication type:

Letter

Differential seeding and propagating efficiency of α-synuclein strains generated in different conditions.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00242-5

By:

Liu, Di;
Guo, Jian-Jun;
Su, Ji-Hui;
Svanbergsson, Alexander;
Yuan, Lin;
Haikal, Caroline;
Li, Wen;
Gouras, Gunnar;
Li, Jia-Yi

Publication type:

Article

Parkinson's disease–associated VPS35 mutant reduces mitochondrial membrane potential and impairs PINK1/Parkin-mediated mitophagy.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00243-4

By:

Ma, Kai Yu;
Fokkens, Michiel R.;
Reggiori, Fulvio;
Mari, Muriel;
Verbeek, Dineke S.

Publication type:

Article

Associations of cerebrospinal fluid amyloidogenic nanoplaques with cytokines in Alzheimer's disease.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00244-3

By:

Aksnes, Mari;
Aass, Hans Christian D.;
Tiiman, Ann;
Edwin, Trine Holt;
Terenius, Lars;
Bogdanović, Nenad;
Vukojević, Vladana;
Knapskog, Anne-Brita

Publication type:

Article

Associations of cerebrospinal fluid amyloidogenic nanoplaques with cytokines in Alzheimer's disease.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00244-3

By:

Aksnes, Mari;
Aass, Hans Christian D.;
Tiiman, Ann;
Edwin, Trine Holt;
Terenius, Lars;
Bogdanović, Nenad;
Vukojević, Vladana;
Knapskog, Anne-Brita

Publication type:

Article

Disruption of orbitofrontal-hypothalamic projections in a murine ALS model and in human patients.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00241-6

By:

Bayer, David;
Antonucci, Stefano;
Müller, Hans-Peter;
Saad, Rami;
Dupuis, Luc;
Rasche, Volker;
Böckers, Tobias M.;
Ludolph, Albert C.;
Kassubek, Jan;
Roselli, Francesco

Publication type:

Article

Neurodegenerative diseases: a hotbed for splicing defects and the potential therapies.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00240-7

By:

Li, Dunhui;
McIntosh, Craig Stewart;
Mastaglia, Frank Louis;
Wilton, Steve Donald;
Aung-Htut, May Thandar

Publication type:

Article

Plasma glial fibrillary acidic protein and neurofilament light chain for the diagnostic and prognostic evaluation of frontotemporal dementia.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00275-w

By:

Zhu, Nuole;
Santos-Santos, Miguel;
Illán-Gala, Ignacio;
Montal, Victor;
Estellés, Teresa;
Barroeta, Isabel;
Altuna, Miren;
Arranz, Javier;
Muñoz, Laia;
Belbin, Olivia;
Sala, Isabel;
Sánchez-Saudinós, Maria Belén;
Subirana, Andrea;
Videla, Laura;
Pegueroles, Jordi;
Blesa, Rafael;
Clarimón, Jordi;
Carmona-Iragui, Maria;
Fortea, Juan;
Lleó, Alberto

Publication type:

Article

COVID-19 and Alzheimer's disease: how one crisis worsens the other.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00237-2

By:

Xia, Xiaohuan;
Wang, Yi;
Zheng, Jialin

Publication type:

Article

Effectiveness and mechanisms of adipose-derived stem cell therapy in animal models of Parkinson's disease: a systematic review and meta-analysis.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00238-1

By:

Li, Keya;
Li, Xinyue;
Shi, Guiying;
Lei, Xuepei;
Huang, Yiying;
Bai, Lin;
Qin, Chuan

Publication type:

Article

Acrolein scavenger dimercaprol offers neuroprotection in an animal model of Parkinson's disease: implication of acrolein and TRPA1.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00239-0

By:

Shi, Liangqin;
Lin, Yazhou;
Jiao, Yucheng;
Herr, Seth A.;
Tang, Jonathan;
Rogers, Edmond;
Chen, Zhengli;
Shi, Riyi

Publication type:

Article

Associations of AT(N) biomarkers with neuropsychiatric symptoms in preclinical Alzheimer's disease and cognitively unimpaired individuals.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00236-3

By:

Ng, Kok Pin;
Chiew, Hui;
Rosa-Neto, Pedro;
Kandiah, Nagaendran;
Ismail, Zahinoor;
Gauthier, Serge

Publication type:

Article

Pharmacological inhibition of asparaginyl endopeptidase by δ-secretase inhibitor 11 mitigates Alzheimer's disease-related pathologies in a senescence-accelerated mouse model.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00235-4

By:

Wang, Ju;
Hu, Hui-Jie;
Liu, Zi-Kai;
Liu, Jing-Jing;
Wang, Shan-Shan;
Cheng, Qing;
Chen, Hong-Zhuan;
Song, Mingke

Publication type:

Article

Ultrasensitive assays for detection of plasma tau and phosphorylated tau 181 in Alzheimer's disease: a systematic review and meta-analysis.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00234-5

By:

Ding, Xulong;
Zhang, Shuting;
Jiang, Lijun;
Wang, Lu;
Li, Tao;
Lei, Peng

Publication type:

Article

An old weapon with a new function: PIWI-interacting RNAs in neurodegenerative diseases.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00233-6

By:

Huang, Xiaobing;
Wong, Garry

Publication type:

Article

Ecto-GPR37: a potential biomarker for Parkinson's disease.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00232-7

By:

Morató, Xavier;
Garcia-Esparcia, Paula;
Argerich, Josep;
Llorens, Franc;
Zerr, Inga;
Paslawski, Wojciech;
Borràs, Eva;
Sabidó, Eduard;
Petäjä-Repo, Ulla E.;
Fernández-Dueñas, Víctor;
Ferrer, Isidro;
Svenningsson, Per;
Ciruela, Francisco

Publication type:

Article

Recommendations for the diagnosis and treatment of paroxysmal kinesigenic dyskinesia: an expert consensus in China.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00231-8

By:

Cao, Li;
Huang, Xiaojun;
Wang, Ning;
Wu, Zhiying;
Zhang, Cheng;
Gu, Weihong;
Cong, Shuyan;
Ma, Jianhua;
Wei, Ling;
Deng, Yanchun;
Fang, Qi;
Niu, Qi;
Wang, Jin;
Wang, Zhaoxia;
Yin, You;
Tian, Jinyong;
Tian, Shufen;
Bi, Hongyan;
Jiang, Hong;
Liu, Xiaorong

Publication type:

Article

Advances in retina imaging as potential biomarkers for early diagnosis of Alzheimer's disease.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00230-9

By:

Zhang, Ying;
Wang, Yanjiang;
Shi, Ce;
Shen, Meixiao;
Lu, Fan

Publication type:

Article

Multitasking guardian of mitochondrial quality: Parkin function and Parkinson's disease.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-020-00229-8

By:

Kamienieva, Iryna;
Duszyński, Jerzy;
Szczepanowska, Joanna

Publication type:

Article

Cross-talks among GBA mutations, glucocerebrosidase, and α-synuclein in GBA-associated Parkinson's disease and their targeted therapeutic approaches: a comprehensive review.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-020-00226-x

By:

Behl, Tapan;
Kaur, Gagandeep;
Fratila, Ovidiu;
Buhas, Camelia;
Judea-Pusta, Claudia Teodora;
Negrut, Nicoleta;
Bustea, Cristiana;
Bungau, Simona

Publication type:

Article

Aberrations of biochemical indicators in amyotrophic lateral sclerosis: a systematic review and meta-analysis.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-020-00228-9

By:

Cheng, Yangfan;
Chen, Yongping;
Shang, Huifang

Publication type:

Article

Neuropsychiatric symptoms are early indicators of an upcoming metabolic decline in Alzheimer's disease.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-020-00225-y

By:

Ng, Kok Pin;
Pascoal, Tharick A.;
Mathotaarachchi, Sulantha;
Chan, Yiong Huak;
Jiang, Lai;
Therriault, Joseph;
Benedet, Andrea L.;
Shin, Monica;
Kandiah, Nagaendran;
Greenwood, Celia M. T.;
Rosa-Neto, Pedro;
Gauthier, Serge

Publication type:

Article

Plasma glial fibrillary acidic protein and neurofilament light chain for the diagnostic and prognostic evaluation of frontotemporal dementia.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00275-w

By:

Zhu, Nuole;
Santos-Santos, Miguel;
Illán-Gala, Ignacio;
Montal, Victor;
Estellés, Teresa;
Barroeta, Isabel;
Altuna, Miren;
Arranz, Javier;
Muñoz, Laia;
Belbin, Olivia;
Sala, Isabel;
Sánchez-Saudinós, Maria Belén;
Subirana, Andrea;
Videla, Laura;
Pegueroles, Jordi;
Blesa, Rafael;
Clarimón, Jordi;
Carmona-Iragui, Maria;
Fortea, Juan;
Lleó, Alberto

Publication type:

Article

Gram-negative bacteria and their lipopolysaccharides in Alzheimer’s disease: pathologic roles and therapeutic implications.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00273-y

By:

Kim, Hyeon soo;
Kim, Sujin;
Shin, Soo Jung;
Park, Yong Ho;
Nam, Yunkwon;
Kim, Chae won;
Lee, Kang won;
Kim, Sung-Min;
Jung, In Duk;
Yang, Hyun Duk;
Park, Yeong-Min;
Moon, Minho

Publication type:

Article

Effects of transcranial ultrasound stimulation pulsed at 40 Hz on Aβ plaques and brain rhythms in 5×FAD mice.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00274-x

By:

Park, Mincheol;
Hoang, Gia Minh;
Nguyen, Thien;
Lee, Eunkyung;
Jung, Hyun Jin;
Choe, Youngshik;
Lee, Moon Hwan;
Hwang, Jae Youn;
Kim, Jae Gwan;
Kim, Tae

Publication type:

Article

Novel multivalent design of a monoclonal antibody improves binding strength to soluble aggregates of amyloid beta.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00258-x

By:

Rofo, Fadi;
Buijs, Jos;
Falk, Ronny;
Honek, Ken;
Lannfelt, Lars;
Lilja, Anna M.;
Metzendorf, Nicole G.;
Gustavsson, Tobias;
Sehlin, Dag;
Söderberg, Linda;
Hultqvist, Greta

Publication type:

Article

TLR2 and TLR4 in Parkinson's disease pathogenesis: the environment takes a toll on the gut.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00271-0

By:

Gorecki, Anastazja M.;
Anyaegbu, Chidozie C.;
Anderton, Ryan S.

Publication type:

Article

TLR2 and TLR4 in Parkinson's disease pathogenesis: the environment takes a toll on the gut.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00271-0

By:

Gorecki, Anastazja M.;
Anyaegbu, Chidozie C.;
Anderton, Ryan S.

Publication type:

Article

New perspectives on cytoskeletal dysregulation and mitochondrial mislocalization in amyotrophic lateral sclerosis.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00272-z

By:

Theunissen, Frances;
West, Phillip K.;
Brennan, Samuel;
Petrović, Bojan;
Hooshmand, Kosar;
Akkari, P. Anthony;
Keon, Matt;
Guennewig, Boris

Publication type:

Article

The role of pathological tau in synaptic dysfunction in Alzheimer's diseases.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00270-1

By:

Wu, Moxin;
Zhang, Manqing;
Yin, Xiaoping;
Chen, Kai;
Hu, Zhijian;
Zhou, Qin;
Cao, Xianming;
Chen, Zhiying;
Liu, Dan

Publication type:

Article

The role of pathological tau in synaptic dysfunction in Alzheimer's diseases.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00270-1

By:

Wu, Moxin;
Zhang, Manqing;
Yin, Xiaoping;
Chen, Kai;
Hu, Zhijian;
Zhou, Qin;
Cao, Xianming;
Chen, Zhiying;
Liu, Dan

Publication type:

Article

Extensive frontal focused ultrasound mediated blood–brain barrier opening for the treatment of Alzheimer's disease: a proof-of-concept study.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00269-8

By:

Park, So Hee;
Baik, Kyoungwon;
Jeon, Seun;
Chang, Won Seok;
Ye, Byoung Seok;
Chang, Jin Woo

Publication type:

Article

Astrocytes and retrograde degeneration of nigrostriatal dopaminergic neurons in Parkinson's disease: removing axonal debris.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00262-1

By:

Morales, Ingrid;
Puertas-Avendaño, Ricardo;
Sanchez, Alberto;
Perez-Barreto, Adrian;
Rodriguez-Sabate, Clara;
Rodriguez, Manuel

Publication type:

Article

A natural history comparison of SOD1-mutant patients with amyotrophic lateral sclerosis between Chinese and German populations.

Published in:

Translational Neurodegeneration, 2021, v. 10, n. 1, p. 1, doi. 10.1186/s40035-021-00266-x

By:

Tang, Lu;
Dorst, Johannes;
Chen, Lu;
Liu, Xiaolu;
Ma, Yan;
Günther, Kornelia;
Michels, Sebastian;
Müller, Kathrin;
Freischmidt, Axel;
Weishaupt, Jochen H.;
Fan, Dongsheng;
Ludolph, Albert C.

Publication type:

Article