Works matching IS 20011326 AND DT 2025 AND VI 15 AND IP 2

Results: 39

Spatial genomics uncovers cytokines promoting ovarian tumour heterogeneity and immunotherapy resistance.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70248
By:
- Mollaoglu, Gurkan;
- Brown, Brian D.;
- Baccarini, Alessia
Publication type:
Article
CLINICAL AND TRANSLATIONAL MEDICINE.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70259
Publication type:
Article
Ubiquitin‐specific protease 25 improves myocardial ischemia–reperfusion injury by deubiquitinating NLRP3 and negatively regulating NLRP3 inflammasome activity in cardiomyocytes.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70243
By:
- Ye, Bozhi;
- Xu, Diyun;
- Zhong, Lingfeng;
- Wang, Yi;
- Wang, Wei;
- Xu, Haowen;
- Han, Xue;
- Min, Julian;
- Wu, Gaojun;
- Huang, Wenhai;
- Liang, Guang
Publication type:
Article
Deciphering the secret codes in N7‐methylguanosine modification: Context‐dependent function of methyltransferase‐like 1 in human diseases.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70240
By:
- Fang, Huan;
- He, Jing;
- Du, Dan;
- Wang, Xue;
- Xu, Xinyu;
- Lu, Linping;
- Zhou, Yefan;
- Wen, Yangyang;
- He, Fucheng;
- Li, Yingxia;
- Wen, Hongtao;
- Zhou, Mingxia
Publication type:
Article
Adipose tissue deficiency impairs transient lipid accumulation and delays liver regeneration following partial hepatectomy in male Seipin knockout mice.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70238
By:
- Dong, Qianqian;
- Liu, Ziwei;
- Ma, Yidan;
- Chen, Xin;
- Wang, Xiaowei;
- Tang, Jinye;
- Ma, Kexin;
- Liang, Chenxi;
- Wang, Mengyu;
- Wu, Xiaoqin;
- Liu, Yang;
- Zhou, Yaru;
- Yang, Hongyuan;
- Gao, Mingming
Publication type:
Article
Spatial transcriptomics reveals regional characteristics of lupus nephritis in murine kidneys and immune response to prednisolone or Gancao Nourishing‐Yin decoction therapies.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70236
By:
- Chen, Yanjuan;
- Chen, Yong;
- Yang, Xufa;
- Jiang, Zhenyou;
- Liu, Dongzhou;
- Hong, Xiaoping
Publication type:
Article
Erratum for the article "Medial septum tau accumulation induces spatial memory deficit via disrupting medial septum‐hippocampus cholinergic pathway" by Wu et al.
Published in:
2025
Publication type:
Correction Notice
METTL14‐mediated m6A modification of ZFP14 inhibits clear cell renal cell carcinoma progression via promoting STAT3 ubiquitination.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70232
By:
- Liu, Zhuonan;
- Sun, Tianshui;
- Zhang, Zhe;
- Piao, Chiyuan;
- Kong, Chuize;
- Zhang, Xiaotong
Publication type:
Article
SHP2 inhibition and adjuvant therapy synergistically target KIT‐mutant GISTs via ERK1/2‐regulated GSK3β/cyclin D1 pathway.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70231
By:
- He, Chunxiao;
- Yu, Jiaying;
- Mao, Shuang;
- Yang, Shaohua;
- Jiang, Xianming;
- Huang, Lei;
- Li, Mingzhe;
- He, Yulong;
- Zhang, Xinhua;
- Xiang, Xi
Publication type:
Article
The utilisation of ctDNA approaches for residual disease detection during neoadjuvant and perioperative immunotherapy in oesophagogastric cancers.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70223
By:
- Kelly, Ronan J.;
- Anagnostou, Valsamo;
- Lam, Vincent K.;
- Zaidi, Ali H.
Publication type:
Article
Erratum for the "S100A7 as a potential diagnostic and prognostic biomarker of esophageal squamous cell carcinoma promotes M2 macrophage infiltration and angiogenesis" by Zhiliang Lu et al.
Published in:
2025
Publication type:
Correction Notice
Sodium pump subunit NKAα1 protects against diabetic endothelial dysfunction by inhibiting ferroptosis through the autophagy‐lysosome degradation of ACSL4.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70221
By:
- Zhu, Xue‐Xue;
- Su, Jia‐Bao;
- Wang, Fang‐Ming;
- Chai, Xiao‐Ying;
- Chen, Guo;
- Xu, An‐Jing;
- Meng, Xin‐Yu;
- Qiu, Hong‐Bo;
- Sun, Qing‐Yi;
- Wang, Yao;
- Lv, Zhuo‐Lin;
- Zhang, Yuan;
- Liu, Yao;
- Han, Zhi‐Jun;
- Li, Na;
- Sun, Hai‐Jian;
- Lu, Qing‐Bo
Publication type:
Article
HSPG2 could promote normal haematopoiesis in acute myeloid leukaemia patients after complete remission by repairing bone marrow endothelial progenitor cells.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70220
By:
- Li, Chen‐Yuan;
- Wang, Zhen‐Kun;
- Xing, Tong;
- Shen, Meng‐Zhu;
- Zhang, Xin‐Yan;
- Chen, Dan‐Dan;
- Wang, Yu;
- Jiang, Hao;
- Jiang, Qian;
- Huang, Xiao‐Jun;
- Kong, Yuan
Publication type:
Article
Oestrogen suppresses the adipogenesis of fibro/adipogenic progenitors through reactivating the METTL3–ESR1‐mediated loop in post‐menopausal females.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70206
By:
- Zhou, Hao;
- Feng, Shujing;
- Cai, Jinkui;
- Shao, Xiexiang;
- Zhu, Siyuan;
- Zhou, Han;
- Cao, Yongmin;
- Wang, Ru;
- Lin, Xingzuan;
- Wang, Jianhua
Publication type:
Article
Paclitaxel biological synthesis promotes the innovation of anti‐cancer drugs.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70230
By:
- Zhang, Xiaolin;
- Liu, Gang;
- Yan, Jianbin
Publication type:
Article
Large‐scale cluster randomised trial reveals effectiveness of Helicobacter pylori eradication for gastric cancer prevention.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70229
By:
- Liu, Zong‐Chao;
- Li, Wen‐Qing
Publication type:
Article
N6‐Methyladenosine modification mediated by METTL3 promotes DNA‐PKcs expression to induce anlotinib resistance in osteosarcoma.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70228
By:
- Zhang, Yining;
- Shen, Guohong;
- Zhang, Dan;
- Meng, Tingting;
- Lv, Zhaorui;
- Chen, Lei;
- Li, Jianmin;
- Li, Ka
Publication type:
Article
Muscle‐specific gene editing improves molecular and phenotypic defects in a mouse model of myotonic dystrophy type 1.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70227
By:
- Izzo, Mariapaola;
- Battistini, Jonathan;
- Golini, Elisabetta;
- Voellenkle, Christine;
- Provenzano, Claudia;
- Orsini, Tiziana;
- Strimpakos, Georgios;
- Scavizzi, Ferdinando;
- Raspa, Marcello;
- Baci, Denisa;
- Frolova, Svetlana;
- Tastsoglou, Spyros;
- Zaccagnini, Germana;
- Garcia‐Manteiga, Jose Manuel;
- Gourdon, Genevieve;
- Mandillo, Silvia;
- Cardinali, Beatrice;
- Martelli, Fabio;
- Falcone, Germana
Publication type:
Article
Monocyte–macrophage dynamics as key in disparate lung and peripheral immune responses in severe anti‐melanoma differentiation‐associated gene 5‐positive dermatomyositis‐related interstitial lung disease.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70226
By:
- Shi, Jia;
- Pei, Xiaoya;
- Peng, Jinmin;
- Wu, Chanyuan;
- Lv, Yulin;
- Wang, Xiaoman;
- Zhou, Yangzhong;
- Yuan, Xueting;
- Dong, Xingbei;
- Zhou, Shuang;
- Xu, Dong;
- Zhao, Jiuliang;
- Liu, Jun;
- Huang, Jiao;
- Du, Bin;
- Yao, Chen;
- Zeng, Xiaofeng;
- Li, Mengtao;
- Chen, Houzao;
- Wang, Qian
Publication type:
Article
Cell‐free epigenomes enhanced fragmentomics‐based model for early detection of lung cancer.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70225
By:
- Wang, Yadong;
- Guo, Qiang;
- Huang, Zhicheng;
- Song, Liyang;
- Zhao, Fei;
- Gu, Tiantian;
- Feng, Zhe;
- Wang, Haibo;
- Li, Bowen;
- Wang, Daoyun;
- Zhou, Bin;
- Guo, Chao;
- Xu, Yuan;
- Song, Yang;
- Zheng, Zhibo;
- Bing, Zhongxing;
- Li, Haochen;
- Yu, Xiaoqing;
- Fung, Ka Luk;
- Xu, Heqing
Publication type:
Article
Spatial‒temporal heterogeneities of liver cancer and the discovery of the invasive zone.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70224
By:
- Yan, Jiayan;
- Jiang, Zhifeng;
- Zhang, Shiyu;
- Yu, Qichao;
- Lu, Yijun;
- Miao, Runze;
- Tang, Zhaoyou;
- Fan, Jia;
- Wu, Liang;
- Duda, Dan G.;
- Zhou, Jian;
- Yang, Xinrong
Publication type:
Article
EpCAM deficiency causes the premature ageing of intestinal stem cells via EGFR/SP1/mTORC1 pathway.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70219
By:
- Li, Keying;
- Xu, Changlong;
- Liu, Lulu;
- Wang, Yunjuan;
- Chen, Jun;
- Li, Chunyuan;
- Peng, Zitong;
- Li, Xiaoqian;
- Chang, Gang;
- Lei, Zili;
- Yang, Yanhong
Publication type:
Article
Histone methyltransferase KMT2A promotes pulmonary fibrogenesis via targeting pro‐fibrotic factor PU.1 in fibroblasts.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70217
By:
- Lyu, Wenting;
- Wang, Hui;
- Ji, Tong;
- Liu, Ling;
- Chen, Haoran;
- Fan, Li;
- Zhong, Guanning;
- Wan, Naihui;
- Chen, Suwan;
- Chen, Jingyu;
- Cai, Hourong;
- Xu, Hongyang;
- Wang, Dongjin;
- Dai, Jinghong
Publication type:
Article
Single‐cell transcriptomic atlas of different endometriosis indicating that an interaction between endometriosis‐associated mesothelial cells (EAMCs) and ectopic stromal cells may influence progesterone resistance.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70216
By:
- Hou, Shengdi;
- Zhang, Jing;
- Zhang, Zhiqiang;
- Qu, Hong;
- Li, Shuhong;
- Jiang, Ying;
- Liu, Chongdong
Publication type:
Article
Artificial metabzyme‐driven metabolic reprogramming and precision oncology.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70215
By:
- Hu, Xi;
- Ling, Daishun
Publication type:
Article
Multi‐organ transcriptomic atlas reveals hallmarks of labour.
Published in:
2025
By:
- Ni, Duan;
- Nanan, Ralph
Publication type:
Abstract
A comparative genomic study across 396 liver biopsies provides deep insight into FGF21 mode of action as a therapeutic agent in metabolic dysfunction‐associated steatotic liver disease.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70218
By:
- Tang, Shifang;
- Borlak, Jürgen
Publication type:
Article
RNF31 induces paclitaxel resistance by sustaining ALYREF cytoplasmic–nuclear shuttling in human triple‐negative breast cancer.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70203
By:
- Huang, Shumei;
- Shi, Dongni;
- Dai, Shuqin;
- Jiang, Xingyu;
- Wang, Rui;
- Yang, Muwen;
- Chen, Boyu;
- Chen, Xuwei;
- Kong, Lingzhi;
- He, Lixin;
- Deng, Pinwei;
- Chen, Xiangfu;
- Lin, Chuyong;
- Li, Yue;
- Li, Jun;
- Song, Libing;
- Shi, Yawei;
- Wei, Weidong
Publication type:
Article
Role of the FOXM1/CMA/ER stress axis in regulating the progression of nonalcoholic steatohepatitis.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70202
By:
- Ma, Shuoyi;
- Xia, Erzhuo;
- Zhang, Miao;
- Hu, Yinan;
- Tian, Siyuan;
- Zheng, Xiaohong;
- Li, Bo;
- Ma, Gang;
- Su, Rui;
- Sun, Keshuai;
- Fan, Qingling;
- Yang, Fangfang;
- Guo, Guanya;
- Guo, Changcun;
- Shang, Yulong;
- Zhou, Xinmin;
- Zhou, Xia;
- Wang, Jingbo;
- Han, Ying
Publication type:
Article
Proteomic profiling of the serum of patients with COVID‐19 reveals key factors in the path to clinical improvement.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70201
By:
- Seong, Hye;
- Lee, Chae‐Hyeon;
- Park, Seo‐Gyu;
- Choi, Kyoung‐Min;
- Lee, Su‐Min;
- Han, Jisoo;
- Bae, Ha‐Song;
- Han, Su‐Bhin;
- Kim, Sung‐Jin;
- Kim, Eunjung;
- Kim, Jae‐Young;
- Song, Joon Young
Publication type:
Article
Immune profiling of the macroenvironment in colorectal cancer unveils systemic dysfunction and plasticity of immune cells.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70175
By:
- Ke, Haoxian;
- Li, Peisi;
- Li, Zhihao;
- Zeng, Xian;
- Zhang, Chi;
- Luo, Shuzhen;
- Chen, Xiaofang;
- Zhou, Xinlan;
- Dong, Shichen;
- Chen, Shaopeng;
- Huang, Junfeng;
- Yuan, Ming;
- Yu, Runfeng;
- Ye, Shubiao;
- Hu, Tuo;
- Tang, Zhonghui;
- Liu, Dongbin;
- Wu, Kui;
- Wu, Xianrui;
- Lan, Ping
Publication type:
Article
Transcriptome profiles of human preimplantation blastocysts related to mosaicism, developmental speed and competence.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70196
By:
- Li, Song;
- Cai, Bing;
- Liu, Jialiu;
- Xu, Yan;
- Ding, Chenhui;
- Lai, Muhua;
- Zhou, Canquan;
- Xu, Yanwen
Publication type:
Article
Neutrophil extracellular traps promote growth of lung adenocarcinoma by mediating the stability of m6A‐mediated SLC2A3 mRNA‐induced ferroptosis resistance and CD8(+) T cell inhibition.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70192
By:
- Xu, Li;
- Kong, Yi;
- Li, Kang;
- Li, Jia;
- Xu, Fang;
- Xu, Yan;
- Liang, Shuzhi;
- Chen, Bolin
Publication type:
Article
5‐hydroxymethylcytosine features of portal venous blood predict metachronous liver metastases of colorectal cancer and reveal phosphodiesterase 4 as a therapeutic target.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70189
By:
- Xu, Nuo;
- Gao, Zhaoya;
- Wu, Deyan;
- Chen, Hangyu;
- Zhang, Zijian;
- Zhang, Lei;
- Wang, Yuchen;
- Lu, Xuyang;
- Yao, Xu;
- Liu, Xuelan;
- Huang, Yi‐You;
- Qiu, Meiying;
- Wang, Sen;
- Liang, Jinqiang;
- Mao, Can;
- Zhang, Feng;
- Xu, Huimin;
- Wang, Yujiao;
- Li, Xian;
- Chen, Zhexin
Publication type:
Article
Spatial distribution of immune cells and their proximity to STING+ cells are associated with survival in glioblastoma.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70187
By:
- Jeon, Hanwool;
- Kang, Hayeong;
- Im, Jihyun;
- Jo, Suin;
- Jung, Hyunchul;
- Kim, Moinay;
- Kim, Jae Hyun;
- Lee, Eunyeup;
- Kim, Soyoung;
- Kim, Jeong Hoon;
- Hong, Chang‐Ki;
- Kim, Young‐Hoon;
- Song, Sang Woo;
- Park, Jinha;
- Kim, Sang‐Yeob;
- Lee, Seungjoo
Publication type:
Article
E2F1/CDK5/DRP1 axis mediates microglial mitochondrial division and autophagy in the pathogenesis of cerebral ischemia‐reperfusion injury.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70197
By:
- Yuan, Ya‐Jing;
- Chen, Tingting;
- Yang, Yan‐Ling;
- Han, Hao‐Nan;
- Xu, Li‐Ming
Publication type:
Article
Single‐cell transcriptomics and metabolomic analysis reveal adenosine‐derived metabolites over‐representation in pseudohypoxic neuroendocrine tumours.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70159
By:
- Kahan Yossef, Yuval;
- Sela Peremen, Liav;
- Telerman, Alona;
- Goldinger, Gil;
- Malitsky, Sergey;
- Itkin, Maxim;
- Halperin, Reut;
- Peshes Yaloz, Naama;
- Tirosh, Amit
Publication type:
Article
Engineering the future of medicine: Natural products, synthetic biology and artificial intelligence for next‐generation therapeutics.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70146
By:
- Bülbül, Emre F.;
- Bode, Helge B.;
- Schmitt, Steven;
- Bozhüyük, Kenan A. J.
Publication type:
Article
Functional genomics pipeline identifies CRL4 inhibition for the treatment of ovarian cancer.
Published in:
Clinical & Translational Medicine, 2025, v. 15, n. 2, p. 1, doi. 10.1002/ctm2.70078
By:
- Claridge, Sally E.;
- Nath, Shalini;
- Baum, Anneliese;
- Farias, Richard;
- Cavallo, Julie‐Ann;
- Rizvi, Nile M.;
- De Boni, Lamberto;
- Park, Eric;
- Granados, Genesis Lara;
- Hauesgen, Matthew;
- Fernandez‐Rodriguez, Ruben;
- Kozan, Eda Nur;
- Kanshin, Evgeny;
- Huynh, Khoi Q.;
- Chen, Peng‐Jen;
- Wu, Kenneth;
- Ueberheide, Beatrix;
- Mosquera, Juan Miguel;
- Hirsch, Fred R.;
- DeVita, Robert J.
Publication type:
Article

Works matching IS 20011326 AND DT 2025 AND VI 15 AND IP 2

Spatial genomics uncovers cytokines promoting ovarian tumour heterogeneity and immunotherapy resistance.

CLINICAL AND TRANSLATIONAL MEDICINE.

Ubiquitin‐specific protease 25 improves myocardial ischemia–reperfusion injury by deubiquitinating NLRP3 and negatively regulating NLRP3 inflammasome activity in cardiomyocytes.

Deciphering the secret codes in N<sup>7</sup>‐methylguanosine modification: Context‐dependent function of methyltransferase‐like 1 in human diseases.

Adipose tissue deficiency impairs transient lipid accumulation and delays liver regeneration following partial hepatectomy in male Seipin knockout mice.

Spatial transcriptomics reveals regional characteristics of lupus nephritis in murine kidneys and immune response to prednisolone or Gancao Nourishing‐Yin decoction therapies.

Erratum for the article "Medial septum tau accumulation induces spatial memory deficit via disrupting medial septum‐hippocampus cholinergic pathway" by Wu et al.

METTL14‐mediated m6A modification of ZFP14 inhibits clear cell renal cell carcinoma progression via promoting STAT3 ubiquitination.

SHP2 inhibition and adjuvant therapy synergistically target KIT‐mutant GISTs via ERK1/2‐regulated GSK3β/cyclin D1 pathway.

The utilisation of ctDNA approaches for residual disease detection during neoadjuvant and perioperative immunotherapy in oesophagogastric cancers.

Erratum for the "S100A7 as a potential diagnostic and prognostic biomarker of esophageal squamous cell carcinoma promotes M2 macrophage infiltration and angiogenesis" by Zhiliang Lu et al.

Sodium pump subunit NKAα1 protects against diabetic endothelial dysfunction by inhibiting ferroptosis through the autophagy‐lysosome degradation of ACSL4.

HSPG2 could promote normal haematopoiesis in acute myeloid leukaemia patients after complete remission by repairing bone marrow endothelial progenitor cells.

Oestrogen suppresses the adipogenesis of fibro/adipogenic progenitors through reactivating the METTL3–ESR1‐mediated loop in post‐menopausal females.

Paclitaxel biological synthesis promotes the innovation of anti‐cancer drugs.

Large‐scale cluster randomised trial reveals effectiveness of Helicobacter pylori eradication for gastric cancer prevention.

N<sup>6</sup>‐Methyladenosine modification mediated by METTL3 promotes DNA‐PKcs expression to induce anlotinib resistance in osteosarcoma.

Muscle‐specific gene editing improves molecular and phenotypic defects in a mouse model of myotonic dystrophy type 1.

Monocyte–macrophage dynamics as key in disparate lung and peripheral immune responses in severe anti‐melanoma differentiation‐associated gene 5‐positive dermatomyositis‐related interstitial lung disease.

Cell‐free epigenomes enhanced fragmentomics‐based model for early detection of lung cancer.

Spatial‒temporal heterogeneities of liver cancer and the discovery of the invasive zone.

EpCAM deficiency causes the premature ageing of intestinal stem cells via EGFR/SP1/mTORC1 pathway.

Histone methyltransferase KMT2A promotes pulmonary fibrogenesis via targeting pro‐fibrotic factor PU.1 in fibroblasts.

Single‐cell transcriptomic atlas of different endometriosis indicating that an interaction between endometriosis‐associated mesothelial cells (EAMCs) and ectopic stromal cells may influence progesterone resistance.

Artificial metabzyme‐driven metabolic reprogramming and precision oncology.

Multi‐organ transcriptomic atlas reveals hallmarks of labour.

A comparative genomic study across 396 liver biopsies provides deep insight into FGF21 mode of action as a therapeutic agent in metabolic dysfunction‐associated steatotic liver disease.

RNF31 induces paclitaxel resistance by sustaining ALYREF cytoplasmic–nuclear shuttling in human triple‐negative breast cancer.

Role of the FOXM1/CMA/ER stress axis in regulating the progression of nonalcoholic steatohepatitis.

Proteomic profiling of the serum of patients with COVID‐19 reveals key factors in the path to clinical improvement.

Immune profiling of the macroenvironment in colorectal cancer unveils systemic dysfunction and plasticity of immune cells.

Transcriptome profiles of human preimplantation blastocysts related to mosaicism, developmental speed and competence.

Neutrophil extracellular traps promote growth of lung adenocarcinoma by mediating the stability of m6A‐mediated SLC2A3 mRNA‐induced ferroptosis resistance and CD8(+) T cell inhibition.

5‐hydroxymethylcytosine features of portal venous blood predict metachronous liver metastases of colorectal cancer and reveal phosphodiesterase 4 as a therapeutic target.

Spatial distribution of immune cells and their proximity to STING<sup>+</sup> cells are associated with survival in glioblastoma.

E2F1/CDK5/DRP1 axis mediates microglial mitochondrial division and autophagy in the pathogenesis of cerebral ischemia‐reperfusion injury.

Single‐cell transcriptomics and metabolomic analysis reveal adenosine‐derived metabolites over‐representation in pseudohypoxic neuroendocrine tumours.

Engineering the future of medicine: Natural products, synthetic biology and artificial intelligence for next‐generation therapeutics.

Functional genomics pipeline identifies CRL4 inhibition for the treatment of ovarian cancer.