Works in Pharmaceutics, 2025, Vol 17, Issue 5

Results: 140

Novel Drug–Drug Cocrystalline Forms of Carbamazepine with Sulfacetamide: Preparation, Characterization, and In Vitro/In Vivo Performance Evaluation.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 678, doi. 10.3390/pharmaceutics17050678

By:

Boycov, Denis E.;
Drozd, Ksenia V.;
Manin, Alex N.;
Churakov, Andrei V.;
Vlasov, Mikhail Yu.;
Kachalkina, Irina V.;
Perlovich, German L.

Publication type:

Article

Effect of Urea on Drug Extraction Efficiency in Reverse Iontophoresis.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 677, doi. 10.3390/pharmaceutics17050677

By:

Yamauchi, Rie;
Ohno, Shuji;
Obata, Yasuko

Publication type:

Article

Effervescent Tablet Preparation by Twin-Screw Melt Granulation with Sorbitol as a Melt Binder †.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 676, doi. 10.3390/pharmaceutics17050676

By:

Horváth, Zoltán Márk;
Kukuls, Kirils;
Frolova, Alīna Jaroslava;
Žogota, Marta;
Buczkowska, Elżbieta Maria;
Pētersone, Līga;
Mohylyuk, Valentyn

Publication type:

Article

Application of Natural Products in Neurodegenerative Diseases by Intranasal Administration: A Review.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 675, doi. 10.3390/pharmaceutics17050675

By:

Jin, Yu;
Ma, Xinyu;
Liu, Shuo;
Zong, Shiyu;
Cheng, Yunlong;
Zhang, Hong;
Wang, Chunliu;
Li, Ye

Publication type:

Article

Evaluation of Indigo Naturalis Prepared Using a Novel Method: Therapeutic Effects on Experimental Ulcerative Colitis in Mice.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 674, doi. 10.3390/pharmaceutics17050674

By:

Xu, Xianxiang;
Lin, Lin;
Ning, Wenjie;
Zhou, Xinyi;
Ullah, Aftab;
Yang, Huiyong;
Wu, Xunxun;
Diao, Yong

Publication type:

Article

Herbal Medicine: Enhancing the Anticancer Potential of Natural Products in Hepatocellular Carcinoma Therapy Through Advanced Drug Delivery Systems.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 673, doi. 10.3390/pharmaceutics17050673

By:

Muteeb, Ghazala;
El-Morsy, Manar T.;
Abo-Taleb, Mustafa Ali;
Mohamed, Salma K.;
Khafaga, Doaa S. R.

Publication type:

Article

Phytosynthesis and Characterization of Silver Nanoparticles from Antigonon leptopus : Assessment of Antibacterial and Cytotoxic Properties.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 672, doi. 10.3390/pharmaceutics17050672

By:

Gastelum-Cabrera, Marisol;
Mendez-Pfeiffer, Pablo;
Ballesteros-Monrreal, Manuel G.;
Velasco-Rodríguez, Brenda;
Martínez-Flores, Patricia D.;
Silva-Bea, Sergio;
Domínguez-Arca, Vicente;
Prieto, Gerardo;
Barbosa, Silvia;
Otero, Ana;
Taboada, Pablo;
Juárez, Josué

Publication type:

Article

Preparation and Characterization of Ternary Complexes to Improve the Solubility and Dissolution Performance of a Proteolysis-Targeting Chimera Drug.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 671, doi. 10.3390/pharmaceutics17050671

By:

Zhang, Heng;
Wu, Hengqian;
Wang, Lili;
Galarza, Laura Machín;
Wu, Chuanyu;
Li, Mingzhong;
Wang, Zhengping;
Zhou, Erpeng;
Han, Jun

Publication type:

Article

Developing the Oxalate, Fumarate and Succinate Salts of Tetrabenazine: Solid-State Characterization and Solubility.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 670, doi. 10.3390/pharmaceutics17050670

By:

Muresan-Pop, Marieta;
Simon, Viorica;
Borodi, Gheorghe;
Turza, Alexandru

Publication type:

Article

A Green Integrated Approach to Multifunctional Silver Nanoparticles Derived from Aronia melanocarpa.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 669, doi. 10.3390/pharmaceutics17050669

By:

Corciova, Andreia;
Mircea, Cornelia;
Fifere, Adrian;
Turin Moleavin, Ioana-Andreea;
Burlec, Ana Flavia;
Ivanescu, Bianca;
Vlase, Ana-Maria;
Hancianu, Monica;
Macovei, Irina

Publication type:

Article

Novel Delivery of Cyclic-Diguanylate Monophosphate Utilizing Amyloid Depots.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 668, doi. 10.3390/pharmaceutics17050668

By:

Ismail, Maytham;
Beluzo, Benjamin;
Chuikov, Sergei;
Keshamouni, Venkateshwar G.;
Kanapathipillai, Mathumai

Publication type:

Article

Production, Validation, and Exposure Dose Measurement of [ 13 N]Ammonia Under Academic Good Manufacturing Practice Environments.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 667, doi. 10.3390/pharmaceutics17050667

By:

Tomiyoshi, Katsumi;
Namiki, Yuta;
Yang, David J.;
Inoue, Tomio

Publication type:

Article

Exploring the Analgesic Potential of L-Lysine: Molecular Mechanisms, Preclinical Evidence, and Implications for Pharmaceutical Pain Therapy.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 666, doi. 10.3390/pharmaceutics17050666

By:

Alibrahem, Walaa;
Kharrat Helu, Nihad;
Törős, Gréta;
Oláh, Csaba;
Prokisch, József

Publication type:

Article

Evaluation of the Effectiveness of Chitosan-Modified Bone Regeneration Materials: A Systematic Review.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 665, doi. 10.3390/pharmaceutics17050665

By:

Gerova-Vatsova, Tsvetalina;
Peev, Stefan;
Yotsova, Ralitsa;
Rogova, Varvara-Velika

Publication type:

Article

Development of a Liposome Nanoformulation for the Delivery of Lipoic Acid as a Potential Neuroprotective Therapy in Glaucoma.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 664, doi. 10.3390/pharmaceutics17050664

By:

Antezana, Pablo Edmundo;
Arana, Ailen Gala Hvozda;
Municoy, Sofia;
Desimone, Martín Federico;
Evelson, Pablo;
Ferreira, Sandra

Publication type:

Article

Engineering a Dual-Function Starch–Cellulose Composite for Colon-Targeted Probiotic Delivery and Synergistic Gut Microbiota Regulation in Type 2 Diabetes Therapeutics.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 663, doi. 10.3390/pharmaceutics17050663

By:

Liu, Ruixiang;
Ding, Yikang;
Xu, Yujing;
Wu, Qifeng;
Chen, Yanan;
Yan, Guiming;
Yin, Dengke;
Yang, Ye

Publication type:

Article

Feasibility of Hot Melt Extrusion in Converting Water-Based Nanosuspensions into Solid Dosage Forms.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 662, doi. 10.3390/pharmaceutics17050662

By:

Ragucci, Erasmo;
Uboldi, Marco;
Sobczuk, Adam;
Facchetti, Giorgio;
Melocchi, Alice;
Serratoni, Mauro;
Zema, Lucia

Publication type:

Article

Advancing Brain Targeting: Cost-Effective Surface-Modified Nanoparticles for Faster Market Entry.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 661, doi. 10.3390/pharmaceutics17050661

By:

Gomes, Mariana;
Ramalho, Maria João;
Loureiro, Joana A.;
Pereira, Maria Carmo

Publication type:

Article

Cirsium setosum Extract-Loaded Hybrid Nanostructured Scaffolds Incorporating a Temperature-Sensitive Polymer for Mechanically Assisted Wound Healing.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 660, doi. 10.3390/pharmaceutics17050660

By:

Jiang, Xiaojing;
Zhu, Shaoxuan;
Song, Jinying;
Li, Xingwei;
Li, Chengbo;
Hou, Guige;
Gao, Zhongfei

Publication type:

Article

Advanced QbD-Based Process Optimization of Clopidogrel Tablets with Insights into Industrial Manufacturing Design.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 659, doi. 10.3390/pharmaceutics17050659

By:

Bak, Young Woo;
Woo, Mi Ran;
Cho, Hyuk Jun;
Kwon, Taek Kwan;
Im, Ho Teak;
Cho, Jung Hyun;
Choi, Han-Gon

Publication type:

Article

Three-Dimensional-Printed Isoniazid Chewable Gels for On-Demand Latent Tuberculosis Treatment in Children.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 658, doi. 10.3390/pharmaceutics17050658

By:

Moreira, Amanda de O. E.;
Neta, Lêda Maria S. Azevedo;
Pietroluongo, Márcia;
Matos, Ana Paula dos S.;
Correa, Beatriz B.;
Ortiz, Beatriz H.;
Guimarães, André da S.;
Nele, Marcio;
Santos, Carollyne M.;
Fai, Ana Elizabeth C.;
Gonçalves, Maria Helena;
Shimizu, Flávio M.;
Dos Santos, Monique S.;
Moure, Rosemberg B.;
Nascimento, Diogo D.;
Guimarães, André Luis de A.;
Junior, Saint Clair dos S. G.;
Vicosa, Alessandra L.;
Cabral, Lucio M.

Publication type:

Article

Combinatorial Effects of Free and Nanoencapsulated Forms of Cabazitaxel and RAS-Selective Lethal 3 in Breast Cancer Cells.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 657, doi. 10.3390/pharmaceutics17050657

By:

Valsalakumari, Remya;
Feith, Marek;
Pettersen, Solveig;
Åslund, Andreas K. O.;
Mørch, Ýrr;
Skotland, Tore;
Sandvig, Kirsten;
Mælandsmo, Gunhild Mari;
Iversen, Tore-Geir

Publication type:

Article

Newborn Intravenous Injection of Liposomal CRISPR/Cas9 Complex Has No Incidence of Off-Targets or Tumors in Mice.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 656, doi. 10.3390/pharmaceutics17050656

By:

Monteagudo, Vinícius;
Flores, Larissa Cristina Barbosa;
Lopes, Melaine;
Fachel, Flavia Nathiely Silveira;
Martins, Giselle;
Siebert, Marina;
Carniel, Willian da Silva;
Garcez, Tuane Nerissa Alves;
Teixeira, Helder Ferreira;
Matte, Ursula;
Giugliani, Roberto;
Baldo, Guilherme;
Poletto, Édina;
Schuh, Roselena Silvestri

Publication type:

Article

Nanoparticles and Nanomaterials: A Review from the Standpoint of Pharmacy and Medicine.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 655, doi. 10.3390/pharmaceutics17050655

By:

Petrov, Gleb V.;
Koldina, Alena M.;
Ledenev, Oleg V.;
Tumasov, Vladimir N.;
Nazarov, Aleksandr A.;
Syroeshkin, Anton V.

Publication type:

Article

Characterization and Specific Detection of Lactobacillus paracasei -Derived Extracellular Vesicles Using Anti-p40-Modified Au Thin Film.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 654, doi. 10.3390/pharmaceutics17050654

By:

Lee, Kyeongmin;
Cho, Eun-Gyung;
Choi, Youngbo;
Kim, Yunsik;
Lee, Jin Hee;
Hong, Surin

Publication type:

Article

Combining Advanced Therapies with Alternative Treatments: A New Approach to Managing Antimicrobial Resistance?

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 648, doi. 10.3390/pharmaceutics17050648

By:

Kaspute, Greta;
Zebrauskas, Arunas;
Streckyte, Akvile;
Ivaskiene, Tatjana;
Prentice, Urte

Publication type:

Article

From Mechanism to Therapy: The Role of MSC-EVs in Alleviating Radiation-Induced Injuries.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 652, doi. 10.3390/pharmaceutics17050652

By:

Huang, Chong;
Li, Heng;
Zhang, Zhiyue;
Mou, Ting;
Wang, Dandan;
Li, Chenlu;
Tian, Lei;
Zong, Chunlin

Publication type:

Article

Targeted Drug Delivery to the Spleen and Its Implications for the Prevention and Treatment of Cancer.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 651, doi. 10.3390/pharmaceutics17050651

By:

Khalil, Ikramy A.;
Faheem, Ahmed;
El-Tanani, Mohamed

Publication type:

Article

Generation and Treatment of a Novel Severe Model of Visceral Gaucher Disease by Genetic Therapy.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 650, doi. 10.3390/pharmaceutics17050650

By:

Geard, Amy F.;
Massaro, Giulia;
Hughes, Michael P.;
Arbuthnot, Patrick;
Waddington, Simon N.;
Rahim, Ahad A.

Publication type:

Article

Nanostructured Lipoxin A4: Understanding Its Biological Behavior and Impact on Alzheimer's Disease (Proof of Concept).

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 649, doi. 10.3390/pharmaceutics17050649

By:

Gomes-da-Silva, Natália Cristina;
Xavier-de-Britto, Isabelle;
Soares, Marilia Amável Gomes;
Yoshihara, Natalia Mayumi Andrade;
Ilem Özdemir, Derya;
Ricci-Junior, Eduardo;
Fechine, Pierre Basílio Almeida;
Alencar, Luciana Magalhães Rebelo;
Henriques, Maria das Graças Muller de Oliveira;
Barja-Fidalgo, Thereza Christina;
Follmer, Cristian;
Santos-Oliveira, Ralph

Publication type:

Article

Dissolving Microneedles Containing Lactoferrin Nanosuspension for Enhancement of Antimicrobial and Anti-Inflammatory Effects in the Treatment of Dry Eye Disease.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 653, doi. 10.3390/pharmaceutics17050653

By:

Elhabal, Sammar Fathy;
Faheem, Ahmed Mohsen;
Hababeh, Sandra;
Nelson, Jakline;
Elzohairy, Nahla A.;
AbdelGhany Morsy, Suzan Awad;
Ewedah, Tassneim M.;
Mousa, Ibrahim S.;
Fouad, Marwa A.;
Hamdan, Ahmed Mohsen Elsaid

Publication type:

Article

In Silico Evaluation of the Biopharmaceutical and Pharmacokinetic Behavior of Metronidazole from Coated Colonic Release Matrix Tablets †.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 647, doi. 10.3390/pharmaceutics17050647

By:

Arévalo-Pérez, Roberto;
Maderuelo, Cristina;
Lanao, José M.

Publication type:

Article

Correction: AlMotwaa, S.M.; Al-Otaibi, W.A. Gemcitabine-Loaded Nanocarrier of Essential Oil from Pulicaria crispa : Preparation, Optimization, and In Vitro Evaluation of Anticancer Activity. Pharmaceutics 2022, 14 , 1336.

Published in:

2025

By:

AlMotwaa, Sahar M.;
Al-Otaibi, Waad A.

Publication type:

Correction Notice

Evaluating Immune Activation Feasibility in Pancreatic Ductal Adenocarcinoma via Oxygen Bubble-Induced Anti-Vascular Therapy.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 645, doi. 10.3390/pharmaceutics17050645

By:

Chiu, Tzu-Yun;
Zho, Yi-Jia;
Ho, Yi-Ju

Publication type:

Article

Construction of pH-Sensitive Multifunctional Hydrogel with Synergistic Anti-Inflammatory Effect for Treatment of Diabetic Wounds.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 644, doi. 10.3390/pharmaceutics17050644

By:

Sun, Xiaoyan;
Li, Yan;
Wang, Haifeng;
Meng, Yanqiu;
Dai, Xu;
Du, Lina;
Li, Lei

Publication type:

Article

Novel Resolvin D1-Loaded Biologics as an Advanced Approach for Inflammation Control and Tissue Regeneration: Preparation and Characterization.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 643, doi. 10.3390/pharmaceutics17050643

By:

Xing, Zhe;
Liang, Jingwen;
Sun, Yang;
Dai, Jing;
Cai, Jiazheng;
Fujio, Masahito;
Xu, Yiwen;
An, Xiaoli;
Xue, Ying

Publication type:

Article

Impact of Excipient and Cell Concentration on the Viability, Proliferation, and Adhesion of Mesenchymal Stem Cells: Future Relevance for the Development of a New Advanced Therapy Medicinal Product.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 642, doi. 10.3390/pharmaceutics17050642

By:

Moñivas, Ester;
Aguayo, Concepción;
Rodera, Beatriz;
Zurita, Mercedes

Publication type:

Article

Extracellular Vesicles as Precision Delivery Systems for Biopharmaceuticals: Innovations, Challenges, and Therapeutic Potential.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 641, doi. 10.3390/pharmaceutics17050641

By:

Mohak, Sidhesh;
Fabian, Zsolt

Publication type:

Article

Advances in the Functionalization of Vaccine Delivery Systems: Innovative Strategies and Translational Perspectives.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 640, doi. 10.3390/pharmaceutics17050640

By:

de Moura, Ingrid Andrêssa;
Silva, Anna Jéssica Duarte;
de Macêdo, Larissa Silva;
Melo, Karina Mayumi Tani Bezerra de;
Leal, Lígia Rosa Sales;
Espinoza, Benigno Cristofer Flores;
Invenção, Maria da Conceição Viana;
Pinho, Samara Sousa de;
Freitas, Antonio Carlos de

Publication type:

Article

Editorial on Special Issue "Advances in Natural Products for Cutaneous Application".

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 639, doi. 10.3390/pharmaceutics17050639

By:

Žugić, Ana;
Tadić, Vanja;
Nešić, Ivana

Publication type:

Article

Safety Profile of Gestrinone: A Systematic Review.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 638, doi. 10.3390/pharmaceutics17050638

By:

Fagundes, Vitor Luis;
Barreiro Marques, Nathália Carolina;
Franco de Lima, Amanda;
de Fátima Cobre, Alexandre;
Stumpf Tonin, Fernanda;
Luna Lazo, Raul Edison;
Pontarolo, Roberto

Publication type:

Article

Agents for Fluorescence-Guided Glioblastoma Surgery.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 637, doi. 10.3390/pharmaceutics17050637

By:

Romeo, Eleni;
Tzakos, Andreas G.;
Crook, Timothy;
Syed, Nelofer;
Voulgaris, Spyridon;
Alexiou, George A.

Publication type:

Article

Self-Assembled Cannabigerol-Based Nanoparticles: Design, Synthesis, and Antiproliferative Activity.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 636, doi. 10.3390/pharmaceutics17050636

By:

Amenta, Arianna;
Nordio, Giulia;
Piazzola, Francesco;
Di Paolo, Maria Luisa;
Milani, Fabio;
Giacomini, Martina;
Citarella, Andrea;
Ciriello, Umberto;
Paladino, Giuseppe;
Pellegrino, Sara;
Silvestri, Federica;
Fasano, Valerio;
Dalla Via, Lisa;
Passarella, Daniele

Publication type:

Article

The Regulatory Environment Surrounding Cannabis Medicines in the EU, the USA, and Australia.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 635, doi. 10.3390/pharmaceutics17050635

By:

Jardim, Claudia;
Delgado-Charro, M. Begoña

Publication type:

Article

Preparation of Carrier-Free Inhalable Dry Powder of Rivaroxaban Using Two-Step Milling for Lung-Targeted Delivery.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 634, doi. 10.3390/pharmaceutics17050634

By:

Kim, Young-Jin;
Son, Jaewoon;
Han, Chang-Soo;
Park, Chun-Woong

Publication type:

Article

Gold Nanoparticle-Based Hydrogel: Application in Anticancer Drug Delivery and Wound Healing In Vitro.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 633, doi. 10.3390/pharmaceutics17050633

By:

Gounden, Varshan;
Singh, Moganavelli

Publication type:

Article

GinExtraMed: Focus on Rosa canina L. Extract Encapsulated into Glycethosomes and Allanthosomes for Accelerating Skin Wound Healing.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 632, doi. 10.3390/pharmaceutics17050632

By:

Rossi, Martina;
Rossello, Simone;
Sallustio, Valentina;
Mandrone, Manuela;
Cerchiara, Teresa;
Chiocchio, Ilaria;
Chidichimo, Giuseppe;
Protti, Michele;
Mercolini, Laura;
Luppi, Barbara;
Bigucci, Federica;
Abruzzo, Angela;
Cappadone, Concettina

Publication type:

Article

Impact of pH-Responsive Cisplatin/Ribavirin-Loaded Monodispersed Magnetic Silica Nanocomposite on A549 Lung Cancer Cells.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 631, doi. 10.3390/pharmaceutics17050631

By:

Almohazey, Dana;
Ravinayagam, Vijaya;
Dafalla, Hatim;
Balasamy, Rabindran Jermy

Publication type:

Article

Editorial on Special Issue "Plasmid DNA for Gene Therapy and DNA Vaccine Applications".

Published in:

2025

By:

Kamenšek, Urška

Publication type:

Editorial

Quality by Design (QbD)-Based Development of a Self-Nanoemulsifying Drug Delivery System for the Ocular Delivery of Flurbiprofen.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 629, doi. 10.3390/pharmaceutics17050629

By:

Jeong, Ju-Hwan;
Yoon, Tae-Han;
Ryu, Si-Won;
Kim, Min-Gyeong;
Kim, Gu-Hae;
Oh, Ye-Jin;
Lee, Su-Jeong;
Kwak, Na-Woon;
Bang, Kyu-Ho;
Kim, Kyeong-Soo

Publication type:

Article