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Works matching IS 19466234 AND DT 2021 AND VI 13 AND IP 613

Results: 6

1

A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models.

Published in:

Science Translational Medicine, 2021, v. 13, n. 613, p. 1, doi. 10.1126/scitranslmed.abj1578

By:

Yu, Xufen;
Li, Dongxu;
Kottur, Jithesh;
Shen, Yudao;
Kim, Huen Suk;
Park, Kwang-Su;
Tsai, Yi-Hsuan;
Gong, Weida;
Wang, Jun;
Suzuki, Kyogo;
Parker, Joel;
Herring, Laura;
Kaniskan, H. Ümit;
Cai, Ling;
Jain, Rinku;
Liu, Jing;
Aggarwal, Aneel K;
Wang, Gang Greg;
Jin, Jian

Publication type:

Article

2

Axonal marker neurofilament light predicts long-term outcomes and progressive neurodegeneration after traumatic brain injury.

Published in:

Science Translational Medicine, 2021, v. 13, n. 613, p. 1, doi. 10.1126/scitranslmed.abg9922

By:

Graham, Neil S. N.;
Zimmerman, Karl A.;
Moro, Federico;
Heslegrave, Amanda;
Maillard, Samia Abed;
Bernini, Adriano;
Miroz, John-Paul;
Donat, Cornelius K.;
Lopez, Maria Yanez;
Bourke, Niall;
Jolly, Amy E.;
Mallas, Emma-Jane;
Soreq, Eyal;
Wilson, Mark H.;
Fatania, Gavin;
Roi, Dylan;
Patel, Maneesh C.;
Garbero, Elena;
Nattino, Giovanni;
Baciu, Camelia

Publication type:

Article

3

CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington's disease.

Published in:

Science Translational Medicine, 2021, v. 13, n. 613, p. 1, doi. 10.1126/scitranslmed.abe7104

By:

Picó, Sara;
Parras, Alberto;
Santos-Galindo, María;
Pose-Utrilla, Julia;
Castro, Margarita;
Fraga, Enrique;
Hernández, Ivó H.;
Elorza, Ainara;
Anta, Héctor;
Wang, Nan;
Martí-Sánchez, Laura;
Belloc, Eulàlia;
Garcia-Esparcia, Paula;
Garrido, Juan J.;
Ferrer, Isidro;
Macías-García, Daniel;
Mir, Pablo;
Artuch, Rafael;
Pérez, Belén;
Hernández, Félix

Publication type:

Article

4

Aberrant activation of m6A demethylase FTO renders HIF2α<sup>low/−</sup> clear cell renal cell carcinoma sensitive to BRD9 inhibitors.

Published in:

Science Translational Medicine, 2021, v. 13, n. 613, p. 1, doi. 10.1126/scitranslmed.abf6045

By:

Zhang, ChuanJie;
Chen, Lu;
Lou, WeiJuan;
Su, JunHui;
Huang, JingYi;
Liu, Ao;
Xu, Yang;
He, HongChao;
Gao, Yi;
Xu, DanFeng;
Li, QingQuan

Publication type:

Article

5

ULK1 inhibition promotes oxidative stress–induced differentiation and sensitizes leukemic stem cells to targeted therapy.

Published in:

Science Translational Medicine, 2021, v. 13, n. 613, p. 1, doi. 10.1126/scitranslmed.abd5016

By:

Ianniciello, Angela;
Zarou, Martha M.;
Rattigan, Kevin M.;
Scott, Mary;
Dawson, Amy;
Dunn, Karen;
Brabcova, Zuzana;
Kalkman, Eric R.;
Nixon, Colin;
Michie, Alison M.;
Copland, Mhairi;
Vetrie, David;
Ambler, Martin;
Saxty, Barbara;
Helgason, G. Vignir

Publication type:

Article

6

APOE3-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia.

Published in:

Science Translational Medicine, 2021, v. 13, n. 613, p. 1, doi. 10.1126/scitranslmed.abc9375

By:

Liu, Chia-Chen;
Murray, Melissa E.;
Li, Xia;
Zhao, Na;
Wang, Na;
Heckman, Michael G.;
Shue, Francis;
Martens, Yuka;
Li, Yonghe;
Raulin, Ana-Caroline;
Rosenberg, Cassandra L.;
Doss, Sydney V.;
Zhao, Jing;
Wren, Melissa C.;
Jia, Lin;
Ren, Yingxue;
Ikezu, Tadafumi C.;
Lu, Wenyan;
Fu, Yuan;
Caulfield, Thomas

Publication type:

Article