Works matching IS 19466234 AND DT 2021 AND VI 13 AND IP 613

Results: 6

ULK1 inhibition promotes oxidative stress–induced differentiation and sensitizes leukemic stem cells to targeted therapy.
Published in:
Science Translational Medicine, 2021, v. 13, n. 613, p. 1, doi. 10.1126/scitranslmed.abd5016
By:
- Ianniciello, Angela;
- Zarou, Martha M.;
- Rattigan, Kevin M.;
- Scott, Mary;
- Dawson, Amy;
- Dunn, Karen;
- Brabcova, Zuzana;
- Kalkman, Eric R.;
- Nixon, Colin;
- Michie, Alison M.;
- Copland, Mhairi;
- Vetrie, David;
- Ambler, Martin;
- Saxty, Barbara;
- Helgason, G. Vignir
Publication type:
Article
A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models.
Published in:
Science Translational Medicine, 2021, v. 13, n. 613, p. 1, doi. 10.1126/scitranslmed.abj1578
By:
- Yu, Xufen;
- Li, Dongxu;
- Kottur, Jithesh;
- Shen, Yudao;
- Kim, Huen Suk;
- Park, Kwang-Su;
- Tsai, Yi-Hsuan;
- Gong, Weida;
- Wang, Jun;
- Suzuki, Kyogo;
- Parker, Joel;
- Herring, Laura;
- Kaniskan, H. Ümit;
- Cai, Ling;
- Jain, Rinku;
- Liu, Jing;
- Aggarwal, Aneel K;
- Wang, Gang Greg;
- Jin, Jian
Publication type:
Article
Aberrant activation of m6A demethylase FTO renders HIF2α<sup>low/−</sup> clear cell renal cell carcinoma sensitive to BRD9 inhibitors.
Published in:
Science Translational Medicine, 2021, v. 13, n. 613, p. 1, doi. 10.1126/scitranslmed.abf6045
By:
- Zhang, ChuanJie;
- Chen, Lu;
- Lou, WeiJuan;
- Su, JunHui;
- Huang, JingYi;
- Liu, Ao;
- Xu, Yang;
- He, HongChao;
- Gao, Yi;
- Xu, DanFeng;
- Li, QingQuan
Publication type:
Article
CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington's disease.
Published in:
Science Translational Medicine, 2021, v. 13, n. 613, p. 1, doi. 10.1126/scitranslmed.abe7104
By:
- Picó, Sara;
- Parras, Alberto;
- Santos-Galindo, María;
- Pose-Utrilla, Julia;
- Castro, Margarita;
- Fraga, Enrique;
- Hernández, Ivó H.;
- Elorza, Ainara;
- Anta, Héctor;
- Wang, Nan;
- Martí-Sánchez, Laura;
- Belloc, Eulàlia;
- Garcia-Esparcia, Paula;
- Garrido, Juan J.;
- Ferrer, Isidro;
- Macías-García, Daniel;
- Mir, Pablo;
- Artuch, Rafael;
- Pérez, Belén;
- Hernández, Félix
Publication type:
Article
Axonal marker neurofilament light predicts long-term outcomes and progressive neurodegeneration after traumatic brain injury.
Published in:
Science Translational Medicine, 2021, v. 13, n. 613, p. 1, doi. 10.1126/scitranslmed.abg9922
By:
- Graham, Neil S. N.;
- Zimmerman, Karl A.;
- Moro, Federico;
- Heslegrave, Amanda;
- Maillard, Samia Abed;
- Bernini, Adriano;
- Miroz, John-Paul;
- Donat, Cornelius K.;
- Lopez, Maria Yanez;
- Bourke, Niall;
- Jolly, Amy E.;
- Mallas, Emma-Jane;
- Soreq, Eyal;
- Wilson, Mark H.;
- Fatania, Gavin;
- Roi, Dylan;
- Patel, Maneesh C.;
- Garbero, Elena;
- Nattino, Giovanni;
- Baciu, Camelia
Publication type:
Article
APOE3-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia.
Published in:
Science Translational Medicine, 2021, v. 13, n. 613, p. 1, doi. 10.1126/scitranslmed.abc9375
By:
- Liu, Chia-Chen;
- Murray, Melissa E.;
- Li, Xia;
- Zhao, Na;
- Wang, Na;
- Heckman, Michael G.;
- Shue, Francis;
- Martens, Yuka;
- Li, Yonghe;
- Raulin, Ana-Caroline;
- Rosenberg, Cassandra L.;
- Doss, Sydney V.;
- Zhao, Jing;
- Wren, Melissa C.;
- Jia, Lin;
- Ren, Yingxue;
- Ikezu, Tadafumi C.;
- Lu, Wenyan;
- Fu, Yuan;
- Caulfield, Thomas
Publication type:
Article

Works matching IS 19466234 AND DT 2021 AND VI 13 AND IP 613

ULK1 inhibition promotes oxidative stress–induced differentiation and sensitizes leukemic stem cells to targeted therapy.

A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models.

Aberrant activation of m6A demethylase FTO renders HIF2α<sup>low/−</sup> clear cell renal cell carcinoma sensitive to BRD9 inhibitors.

CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington's disease.

Axonal marker neurofilament light predicts long-term outcomes and progressive neurodegeneration after traumatic brain injury.

APOE3-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia.