Works matching IS 19466234 AND DT 2021 AND VI 13 AND IP 594

Results: 7

Cellular senescence inhibits renal regeneration after injury in mice, with senolytic treatment promoting repair.
Published in:
Science Translational Medicine, 2021, v. 13, n. 594, p. 1, doi. 10.1126/scitranslmed.abb0203
By:
- Mylonas, Katie J.;
- O'Sullivan, Eoin D.;
- Humphries, Duncan;
- Baird, David P.;
- Docherty, Marie-Helena;
- Neely, Sarah A.;
- Krimpenfort, Paul J.;
- Melk, Anette;
- Schmitt, Roland;
- Ferreira-Gonzalez, Sofia;
- Forbes, Stuart J.;
- Hughes, Jeremy;
- Ferenbach, David A.
Publication type:
Article
Na<sub>v</sub>1.7 target modulation and efficacy can be measured in nonhuman primate assays.
Published in:
Science Translational Medicine, 2021, v. 13, n. 594, p. 1, doi. 10.1126/scitranslmed.aay1050
By:
- Kraus, Richard L.;
- Zhao, Fuqiang;
- Pall, Parul S.;
- Zhou, Dan;
- Vardigan, Joshua D.;
- Danziger, Andrew;
- Li, Yuxing;
- Daley, Christopher;
- Ballard, Jeanine E.;
- Clements, Michelle K.;
- Klein, Rebecca M.;
- Holahan, Marie A.;
- Greshock, Thomas J.;
- Kim, Ronald M.;
- Layton, Mark E.;
- Burgey, Christopher S.;
- Serra, Jordi;
- Henze, Darrell A.;
- Houghton, Andrea K.
Publication type:
Article
ABCB10 exports mitochondrial biliverdin, driving metabolic maladaptation in obesity.
Published in:
Science Translational Medicine, 2021, v. 13, n. 594, p. 1, doi. 10.1126/scitranslmed.abd1869
By:
- Shum, Michael;
- Shintre, Chitra A.;
- Althoff, Thorsten;
- Gutierrez, Vincent;
- Segawa, Mayuko;
- Saxberg, Alexandra D.;
- Martinez, Melissa;
- Adamson, Roslin;
- Young, Margaret R.;
- Faust, Belinda;
- Gharakhanian, Raffi;
- Su, Shi;
- Chella Krishnan, Karthickeyan;
- Mahdaviani, Kiana;
- Veliova, Michaela;
- Wolf, Dane M.;
- Ngo, Jennifer;
- Nocito, Laura;
- Stiles, Linsey;
- Abramson, Jeff
Publication type:
Article
Dendritic cell targeting with Fc-enhanced CD40 antibody agonists induces durable antitumor immunity in humanized mouse models of bladder cancer.
Published in:
Science Translational Medicine, 2021, v. 13, n. 594, p. 1, doi. 10.1126/scitranslmed.abd1346
By:
- Garris, Christopher S.;
- Wong, Jeffrey L.;
- Ravetch, Jeffrey V.;
- Knorr, David A.
Publication type:
Article
A method to delineate de novo missense variants across pathways prioritizes genes linked to autism.
Published in:
Science Translational Medicine, 2021, v. 13, n. 594, p. 1, doi. 10.1126/scitranslmed.abc1739
By:
- Koire, Amanda;
- Katsonis, Panagiotis;
- Kim, Young Won;
- Buchovecky, Christie;
- Wilson, Stephen J.;
- Lichtarge, Olivier
Publication type:
Article
cIAP1/2 antagonism eliminates MHC class I–negative tumors through T cell–dependent reprogramming of mononuclear phagocytes.
Published in:
Science Translational Medicine, 2021, v. 13, n. 594, p. 1, doi. 10.1126/scitranslmed.abf5058
By:
- Roehle, Kevin;
- Qiang, Li;
- Ventre, Katherine S.;
- Heid, Daniel;
- Ali, Lestat R.;
- Lenehan, Patrick;
- Heckler, Max;
- Crowley, Stephanie J.;
- Stump, Courtney T.;
- Ro, Gabrielle;
- Godicelj, Anže;
- Bhuiyan, Aladdin M.;
- Yang, Annan;
- Quiles del Rey, Maria;
- Biary, Tamara;
- Luoma, Adrienne M.;
- Bruck, Patrick T.;
- Tegethoff, Jana F.;
- Nopper, Svenja L.;
- Li, Jinyang
Publication type:
Article
Gene therapy restores dopamine transporter expression and ameliorates pathology in iPSC and mouse models of infantile parkinsonism.
Published in:
Science Translational Medicine, 2021, v. 13, n. 594, p. 1, doi. 10.1126/scitranslmed.aaw1564
By:
- Ng, Joanne;
- Barral, Serena;
- De La Fuente Barrigon, Carmen;
- Lignani, Gabriele;
- Erdem, Fatma A.;
- Wallings, Rebecca;
- Privolizzi, Riccardo;
- Rossignoli, Giada;
- Alrashidi, Haya;
- Heasman, Sonja;
- Meyer, Esther;
- Ngoh, Adeline;
- Pope, Simon;
- Karda, Rajvinder;
- Perocheau, Dany;
- Baruteau, Julien;
- Suff, Natalie;
- Antinao Diaz, Juan;
- Schorge, Stephanie;
- Vowles, Jane
Publication type:
Article

Works matching IS 19466234 AND DT 2021 AND VI 13 AND IP 594

Cellular senescence inhibits renal regeneration after injury in mice, with senolytic treatment promoting repair.

Na<sub>v</sub>1.7 target modulation and efficacy can be measured in nonhuman primate assays.

ABCB10 exports mitochondrial biliverdin, driving metabolic maladaptation in obesity.

Dendritic cell targeting with Fc-enhanced CD40 antibody agonists induces durable antitumor immunity in humanized mouse models of bladder cancer.

A method to delineate de novo missense variants across pathways prioritizes genes linked to autism.

cIAP1/2 antagonism eliminates MHC class I–negative tumors through T cell–dependent reprogramming of mononuclear phagocytes.

Gene therapy restores dopamine transporter expression and ameliorates pathology in iPSC and mouse models of infantile parkinsonism.