Works matching IS 19466234 AND DT 2017

Results: 248

A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.
Published in:
Science Translational Medicine, 2017, v. 9, n. 421, p. 1, doi. 10.1126/scitranslmed.aai7635
By:
- Ryan, Katie J.;
- White, Charles C.;
- Patel, Kruti;
- Xu, Jishu;
- Olah, Marta;
- Replogle, Joseph M.;
- Frangieh, Michael;
- Cimpean, Maria;
- Winn, Phoebe;
- McHenry, Allison;
- Kaskow, Belinda J.;
- Chan, Gail;
- Cuerdon, Nicole;
- Bennett, David A.;
- Boyd, Justin D.;
- Imitola, Jaime;
- Elyaman, Wassim;
- De Jager, Philip L.;
- Bradshaw, Elizabeth M.
Publication type:
Article
Hippocampal extracellular matrix alterations contribute to cognitive impairment associated with a chronic depressive-like state in rats.
Published in:
Science Translational Medicine, 2017, v. 9, n. 421, p. 1, doi. 10.1126/scitranslmed.aai8753
By:
- Riga, Danai;
- Kramvis, Ioannis;
- Koskinen, Maija K.;
- van Bokhoven, Pieter;
- van der Harst, Johanneke E.;
- Heistek, Tim S.;
- Timmerman, A. Jaap;
- van Nierop, Pim;
- van der Schors, Roel C.;
- Pieneman, Anton W.;
- de Weger, Anouk;
- van Mourik, Yvar;
- Schoffelmeer, Anton N. M.;
- Mansvelder, Huib D.;
- Meredith, MRhiannon M.;
- Hoogendijk, Witte J. G.;
- Smit, August B.;
- Spijker, Sabine
Publication type:
Article
Human ESC-derived retinal epithelial cell sheets potentiate rescue of photoreceptor cell loss in rats with retinal degeneration.
Published in:
Science Translational Medicine, 2017, v. 9, n. 421, p. 1
By:
- M'Barek, Karim Ben;
- Habeler, Walter;
- Plancheron, Alexandra;
- Mohamed Jarraya Mohamed;
- Regent, Florian;
- Terray, Angélique;
- Ying Yang;
- Chatrousse, Laure;
- Domingues, Sophie;
- Masson, Yolande;
- Sahel, José-Alain;
- Peschanski, Marc;
- Goureau, Olivier;
- Monville, Christelle
Publication type:
Article
Enhanced human hematopoietic stem and progenitor cell engraftment by blocking donor T cell-mediated TNF-signaling.
Published in:
Science Translational Medicine, 2017, v. 9, n. 421, p. 1
By:
- Weijia Wang;
- Hisaki Fujii;
- Hye Jin Kim;
- Hermansa, Karin;
- Usenko, Tatiana;
- Xie, Stephanie;
- Zhi-Juan Luo;
- Ma, Jennifer;
- Celso, Cristina Lo;
- Dick, John E.;
- Krueger, Joerg;
- Wall, Donna;
- Egeler, R. Maarten;
- Zandstra, Peter W.
Publication type:
Article
Vaccination of dogs in an African city interrupts rabies transmission and reduces human exposure.
Published in:
Science Translational Medicine, 2017, v. 9, n. 421, p. 1, doi. 10.1126/scitranslmed.aaf6984
By:
- Zinsstag, Jakob;
- Lechenne, Monique;
- Laager, Mirjam;
- Mindekem, Rolande;
- Naïssengar, Service;
- Oussiguéré, Assandi;
- Bidjeh, Kebkiba;
- Rives, Germain;
- Tessier, Julie;
- Madjaninan, Seraphin;
- Ouagal, Mahamat;
- Moto, Daugla D.;
- Alfaroukh, Idriss O.;
- Muthiani, Yvonne;
- Traoré, Abdallah;
- Hattendorf, Jan;
- Lepelletier, Anthony;
- Kergoat, Lauriane;
- Bourhy, Hervé;
- Dacheux, Laurent
Publication type:
Article
Durability and correlates of vaccine protection against Zika virus in rhesus monkeys.
Published in:
Science Translational Medicine, 2017, v. 9, n. 420, p. 1, doi. 10.1126/scitranslmed.aao4163
By:
- Abbink, Peter;
- Larocca, Rafael A.;
- Visitsunthorn, Kittipos;
- Boyd, Michael;
- De La Barrera, Rafael A.;
- Gromowski, Gregory D.;
- Kirilova, Marinela;
- Peterson, Rebecca;
- Zhenfeng Li;
- Nanayakkara, Ovini;
- Nityanandam, Ramya;
- Mercado, Noe B.;
- Borducchi, Erica N.;
- Chandrashekar, Abishek;
- Jetton, David;
- Mojta, Shanell;
- Gandhi, Priya;
- LeSuer, Jake;
- Khatiwada, Shreeya;
- Lewis, Mark G.
Publication type:
Article
Effect of population viral load on prospective HIV incidence in a hyperendemic rural African community.
Published in:
Science Translational Medicine, 2017, v. 9, n. 420, p. 1, doi. 10.1126/scitranslmed.aam8012
By:
- Tanser, Frank;
- Vandormael, Alain;
- Cuadros, Diego;
- Phillips, Andrew N.;
- de Oliveira, Tulio;
- Tomita, Andrew;
- Bärnighausen, Till;
- Pillay, Deenan
Publication type:
Article
Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis.
Published in:
Science Translational Medicine, 2017, v. 9, n. 420, p. 1, doi. 10.1126/scitranslmed.aal3765
By:
- Lagares, David;
- Santos, Alba;
- Grasberger, Paula E.;
- Fei Liu;
- Probst, Clemens K.;
- Rahimi, Rod A.;
- Norihiko Sakai;
- Kuehl, Tobias;
- Ryan, Jeremy;
- Bhola, Patrick;
- Montero, Joan;
- Kapoor, Mohit;
- Baron, Murray;
- Varelas, Xaralabos;
- Tschumperlin, Daniel J.;
- Letai, Anthony;
- Tager, Andrew M.
Publication type:
Article
Urine lipoarabinomannan glycan in HIV-negative patients with pulmonary tuberculosis correlates with disease severity.
Published in:
Science Translational Medicine, 2017, v. 9, n. 420, p. 1, doi. 10.1126/scitranslmed.aal2807
By:
- Paris, Luisa;
- Magni, Ruben;
- Zaidi, Fatima;
- Araujo, Robyn;
- Saini, Neal;
- Harpole, Michael;
- Coronel, Jorge;
- Kirwan, Daniela E.;
- Steinberg, Hannah;
- Gilman, Robert H.;
- Petricoin III, Emanuel F.;
- Nisini, Roberto;
- Luchini, Alessandra;
- Liotta, Lance
Publication type:
Article
Thorase variants are associated with defects in glutamatergic neurotransmission that can be rescued by Perampanel.
Published in:
Science Translational Medicine, 2017, v. 9, n. 420, p. 1, doi. 10.1126/scitranslmed.aah4985
By:
- Umanah, George K. E.;
- Pignatelli, Marco;
- Xiling Yin;
- Rong Chen;
- Crawford, Joshua;
- Neifert, Stewart;
- Scarffe, Leslie;
- Behensky, Adam A.;
- Guiberson, Noah;
- Chang, Melissa;
- Ma, Erica;
- Jin Wan Kim;
- Castro, Cibele C.;
- Xiaobo Mao;
- Li Chen;
- Andrabi, Shaida A.;
- Pletnikov, Mikhail V.;
- Pulver, Ann E.;
- Avramopoulos, Dimitrios;
- Bonci, Antonello
Publication type:
Article
Clinical trial design: The nobility of randomization.
Published in:
Science Translational Medicine, 2017, v. 9, n. 419, p. 1, doi. 10.1126/scitranslmed.aaq0810
By:
- Michael, Nelson L.
Publication type:
Article
A randomized controlled safety/efficacy trial of therapeutic vaccination in HIV-infected individuals who initiated antiretroviral therapy early in infection.
Published in:
Science Translational Medicine, 2017, v. 9, n. 419, p. 1, doi. 10.1126/scitranslmed.aan8848
By:
- Sneller, Michael C.;
- Justement, J. Shawn;
- Gittens, Kathleen R.;
- Petrone, Mary E.;
- Clarridge, Katherine E.;
- Proschan, Michael A.;
- Kwan, Richard;
- Shi, Victoria;
- Blazkova, Jana;
- Refsland, Eric W.;
- Morris, Daryl E.;
- Cohen, Kristen W.;
- McElrath, M. Juliana;
- Rong Xu;
- Egan, Michael A.;
- Eldridge, John H.;
- Benko, Erika;
- Kovacs, Colin;
- Moir, Susan;
- Tae-Wook Chun
Publication type:
Article
Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy.
Published in:
Science Translational Medicine, 2017, v. 9, n. 418, p. 1, doi. 10.1126/scitranslmed.aan8081
By:
- Amoasii, Leonela;
- Long, Chengzu;
- Hui Li;
- Mireault, Alex A.;
- Shelton, John M.;
- Sanchez-Ortiz, Efrain;
- McAnally, John R.;
- Bhattacharyya, Samadrita;
- Schmidt, Florian;
- Grimm, Dirk;
- Hauschka, Stephen D.;
- Bassel-Duby, Rhonda;
- Olson, Eric N.
Publication type:
Article
Nanoparticle targeting to the endothelium during normothermic machine perfusion of human kidneys.
Published in:
Science Translational Medicine, 2017, v. 9, n. 418, p. 1, doi. 10.1126/scitranslmed.aam6764
By:
- Tietjen, Gregory T.;
- Hosgood, Sarah A.;
- DiRito, Jenna;
- Jiajia Cui;
- Deep, Deeksha;
- Song, Eric;
- Kraehling, Jan R.;
- Piotrowski-Daspit, Alexandra S.;
- Kirkiles-Smith, Nancy C.;
- Al-Lamki, Rafia;
- Thiru, Sathia;
- Bradley, J. Andrew;
- Saeb-Parsy, Kourosh;
- Bradley, John R.;
- Nicholson, Michael L.;
- Saltzman, W. Mark;
- Pober, Jordan S.
Publication type:
Article
Rescue of Pompe disease in mice by AAV-mediated liver delivery of secretable acid α-glucosidase.
Published in:
Science Translational Medicine, 2017, v. 9, n. 418, p. 1, doi. 10.1126/scitranslmed.aam6375
By:
- Puzzo, Francesco;
- Colella, Pasqualina;
- Biferi, Maria G.;
- Bali, Deeksha;
- Paulk, Nicole K.;
- Vidal, Patrice;
- Collaud, Fanny;
- Simon-Sola, Marcelo;
- Charles, Severine;
- Hardet, Romain;
- Leborgne, Christian;
- Meliani, Amine;
- Cohen-Tannoudji, Mathilde;
- Astord, Stephanie;
- Gjata, Bernard;
- Sellier, Pauline;
- van Wittenberghe, Laetitia;
- Vignaud, Alban;
- Boisgerault, Florence;
- Barkats, Martine
Publication type:
Article
A degradation fragment of type X collagen is a real-time marker for bone growth velocity.
Published in:
Science Translational Medicine, 2017, v. 9, n. 419, p. 1, doi. 10.1126/scitranslmed.aan4669
By:
- Coghlan, Ryan F.;
- Oberdorf, Jon A.;
- Sienko, Susan;
- Aiona, Michael D.;
- Boston, Bruce A.;
- Connelly, Kara J.;
- Bahney, Chelsea;
- LaRouche, Jeremie;
- Almubarak, Sarah M.;
- Coleman, Daniel T.;
- Girkontaite, Irute;
- von der Mark, Klaus;
- Lunstrum, Gregory P.;
- Horton, William A.
Publication type:
Article
Irisin protects mitochondria function during pulmonary ischemia/reperfusion injury.
Published in:
Science Translational Medicine, 2017, v. 9, n. 418, p. 1, doi. 10.1126/scitranslmed.aao6298
By:
- Ken Chen;
- Zaicheng Xu;
- Yukai Liu;
- Zhen Wang;
- Yu Li;
- Xuefei Xu;
- Caiyu Chen;
- Tianyang Xia;
- Qiao Liao;
- Yonggang Yao;
- Cindy Zeng;
- Duofen He;
- Yongjian Yang;
- Tao Tan;
- Jianxun Yi;
- Jingsong Zhou;
- Hua Zhu;
- Jianjie Ma;
- Chunyu Zeng
Publication type:
Article
Vasopressin stimulates the proliferation and differentiation of red blood cell precursors and improves recovery from anemia.
Published in:
Science Translational Medicine, 2017, v. 9, n. 418, p. 1, doi. 10.1126/scitranslmed.aao1632
By:
- Mayer, Balázs;
- Németh, Krisztián;
- Krepuska, Miklós;
- Myneni, Vamsee D.;
- Maric, Dragan;
- Tisdale, John F.;
- Hsieh, Matthew M.;
- Naoya Uchida;
- Heon-Jin Lee;
- Nemeth, Michael J.;
- Holmbeck, Kenn;
- Tom Noguchi, Constance;
- Rogers, Heather;
- Dey, Soumyadeep;
- Hansen, Arne;
- Jeffrey Hong;
- Ian Chow;
- Key, Sharon;
- Szalayova, Ildikó;
- Pagani, Jerome
Publication type:
Article
A reversible thermoresponsive sealant for temporary closure of ocular trauma.
Published in:
Science Translational Medicine, 2017, v. 9, n. 419, p. 1, doi. 10.1126/scitranslmed.aan3879
By:
- Bayat, Niki;
- Yi Zhang;
- Falabella, Paulo;
- Menefee, Roby;
- Whalen III, John J.;
- Humayun, Mark S.;
- Thompson, Mark E.
Publication type:
Article
BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions.
Published in:
Science Translational Medicine, 2017, v. 9, n. 419, p. 1, doi. 10.1126/scitranslmed.aam7816
By:
- Fard, Maryam K.;
- van der Meer, Franziska;
- Sánchez, Paula;
- Cantuti-Castelvetri, Ludovico;
- Mandad, Sunit;
- Jäkel, Sarah;
- Fornasiero, Eugenio F.;
- Schmitt, Sebastian;
- Ehrlich, Marc;
- Starost, Laura;
- Kuhlmann, Tanja;
- Sergiou, Christina;
- Schultz, Verena;
- Wrzos, Claudia;
- Brück, Wolfgang;
- Urlaub, Henning;
- Dimou, Leda;
- Stadelmann, Christine;
- Simons, Mikael
Publication type:
Article
PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis.
Published in:
Science Translational Medicine, 2017, v. 9, n. 419, p. 1, doi. 10.1126/scitranslmed.aal2332
By:
- Dickey, Audrey S.;
- Sanchez, Dafne N.;
- Arreola, Martin;
- Sampat, Kunal R.;
- Weiwei Fan;
- Arbez, Nicolas;
- Akimov, Sergey;
- Van Kanegan, Michael J.;
- Ohnishi, Kohta;
- Gilmore-Hall, Stephen K.;
- Flores, April L.;
- Nguyen, Janice M.;
- Lomas, Nicole;
- Hsu, Cynthia L.;
- Lo, Donald C.;
- Ross, Christopher A.;
- Masliah, Eliezer;
- Evans, Ronald M.;
- La Spada, Albert R.
Publication type:
Article
Large-scale proteomics identifies MMP-7 as a sentinel of epithelial injury and of biliary atresia.
Published in:
Science Translational Medicine, 2017, v. 9, n. 417, p. 1, doi. 10.1126/scitranslmed.aan8462
By:
- Lertudomphonwanit, Chatmanee;
- Mourya, Reena;
- Lin Fei;
- Yue Zhang;
- Gutta, Sridevi;
- Li Yang;
- Bove, Kevin E.;
- Shivakumar, Pranavkumar;
- Bezerra, Jorge A.
Publication type:
Article
Integrated genomic and interfacility patient-transfer data reveal the transmission pathways of multidrug-resistant Klebsiella pneumoniae in a regional outbreak.
Published in:
Science Translational Medicine, 2017, v. 9, n. 417, p. 1, doi. 10.1126/scitranslmed.aan0093
By:
- Snitkin, Evan S.;
- Won, Sarah;
- Pirani, Ali;
- Lapp, Zena;
- Weinstein, Robert A.;
- Lolans, Karen;
- Hayden, Mary K.
Publication type:
Article
Targeting STUB1-tissue factor axis normalizes hyperthrombotic uremic phenotype without increasing bleeding risk.
Published in:
Science Translational Medicine, 2017, v. 9, n. 417, p. 1, doi. 10.1126/scitranslmed.aam8475
By:
- Shashar, Moshe;
- Belghasem, Mostafa E.;
- Matsuura, Shinobu;
- Walker, Joshua;
- Richards, Sean;
- Alousi, Faisal;
- Rijal, Keshab;
- Kolachalama, Vijaya B.;
- Balcells, Mercedes;
- Minami Odagi;
- Kazuo Nagasawa;
- Henderson, Joel M.;
- Gautam, Amitabh;
- Rushmore, Richard;
- Francis, Jean;
- Kirchhofer, Daniel;
- Kolandaivelu, Kumaran;
- Sherr, David H.;
- Edelman, Elazer R.;
- Ravid, Katya
Publication type:
Article
Prion seeding activity and infectivity in skin samples from patients with sporadic Creutzfeldt-Jakob disease.
Published in:
Science Translational Medicine, 2017, v. 9, n. 417, p. 1, doi. 10.1126/scitranslmed.aam7785
By:
- Orrú, Christina D.;
- Jue Yuan;
- Appleby, Brian S.;
- Baiya Li;
- Yu Li;
- Winner, Dane;
- Zerui Wang;
- Yi-An Zhan;
- Rodgers, Mark;
- Rarick, Jason;
- Wyza, Robert E.;
- Joshi, Tripti;
- Gong-Xian Wang;
- Cohen, Mark L.;
- Shulin Zhang;
- Groveman, Bradley R.;
- Petersen, Robert B.;
- Ironside, James W.;
- Quiñones-Mateu, Miguel E.;
- Safar, Jiri G.
Publication type:
Article
What evidence do we need for biomarker qualification?
Published in:
Science Translational Medicine, 2017, v. 9, n. 417, p. 1, doi. 10.1126/scitranslmed.aal4599
By:
- Leptak, Chris;
- Menetski, Joseph P.;
- Wagner, John A.;
- Aubrecht, Jiri;
- Brady, Linda;
- Brumfield, Martha;
- Chin, William W.;
- Hoffmann, Steve;
- Kelloff, Gary;
- Lavezzari, Gabriela;
- Ranganathan, Rajesh;
- Sauer, John-Michael;
- Sistare, Frank D.;
- Zabka, Tanja;
- Wholley, David
Publication type:
Article
TCR engagement negatively affects CD8 but not CD4 CAR T cell expansion and leukemic clearance.
Published in:
Science Translational Medicine, 2017, v. 9, n. 417, p. 1, doi. 10.1126/scitranslmed.aag1209
By:
- Yinmeng Yang;
- Kohler, M. Eric;
- Chien, Christopher D.;
- Sauter, Christopher T.;
- Jacoby, Elad;
- Chunhua Yan;
- Ying Hu;
- Wanhainen, Kelsey;
- Haiying Qin;
- Fry, Terry J.
Publication type:
Article
A method of high-throughput functional evaluation of EGFR gene variants of unknown significance in cancer.
Published in:
Science Translational Medicine, 2017, v. 9, n. 416, p. 1, doi. 10.1126/scitranslmed.aan6566
By:
- Shinji Kohsaka;
- Masaaki Nagano;
- Toshihide Ueno;
- Yoshiyuki Suehara;
- Takuo Hayashi;
- Naoko Shimada;
- Kazuhisa Takahashi;
- Kenji Suzuki;
- Kazuya Takamochi;
- Fumiyuki Takahashi;
- Hiroyuki Mano
Publication type:
Article
Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation.
Published in:
Science Translational Medicine, 2017, v. 9, n. 416, p. 1, doi. 10.1126/scitranslmed.aam7828
By:
- Galleu, Antonio;
- Riffo-Vasquez, Yanira;
- Trento, Cristina;
- Lomas, Cara;
- Dolcetti, Luigi;
- Tik Shing Cheung;
- von Bonin, Malte;
- Barbieri, Laura;
- Halai, Krishma;
- Ward, Sophie;
- Ling Weng;
- Chakraverty, Ronjon;
- Lombardi, Giovanna;
- Watt, Fiona M.;
- Orchard, Kim;
- Marks, David I.;
- Apperley, Jane;
- Bornhauser, Martin;
- Walczak, Henning;
- Bennett, Clare
Publication type:
Article
PD-L1 genetic overexpression or pharmacological restoration in hematopoietic stem and progenitor cells reverses autoimmune diabetes.
Published in:
Science Translational Medicine, 2017, v. 9, n. 416, p. 1, doi. 10.1126/scitranslmed.aam7543
By:
- Ben Nasr, Moufida;
- Tezza, Sara;
- D'Addio, Francesca;
- Mameli, Chiara;
- Usuelli, Vera;
- Maestroni, Anna;
- Corradi, Domenico;
- Belletti, Silvana;
- Albarello, Luca;
- Becchi, Gabriella;
- Fadini, Gian Paolo;
- Schuetz, Christian;
- Markmann, James;
- Wasserfall, Clive;
- Zon, Leonard;
- Zuccotti, Gian Vincenzo;
- Fiorina, Paolo
Publication type:
Article
Lung cancer-associated pulmonary hypertension: Role of microenvironmental inflammation based on tumor cell-immune cell cross-talk.
Published in:
Science Translational Medicine, 2017, v. 9, n. 416, p. 1, doi. 10.1126/scitranslmed.aai9048
By:
- Pullamsetti, Soni Savai;
- Kojonazarov, Baktybek;
- Storn, Samantha;
- Gall, Henning;
- Salazar, Ylia;
- Wolf, Janine;
- Weigert, Andreas;
- El-Nikhely, Nefertiti;
- Ghofrani, Hossein Ardeschir;
- Krombach, Gabriele A.;
- Fink, Ludger;
- Gattenlöhner, Stefan;
- Rapp, Ulf R.;
- Schermuly, Ralph Theo;
- Grimminger, Friedrich;
- Seeger, Werner;
- Savai, Rajkumar
Publication type:
Article
A precision therapy against cancers driven by KIT/PDGFRA mutations.
Published in:
Science Translational Medicine, 2017, v. 9, n. 414, p. 1, doi. 10.1126/scitranslmed.aao1690
By:
- Evans, Erica K.;
- Gardino, Alexandra K.;
- Kim, Joseph L.;
- Hodous, Brian L.;
- Shutes, Adam;
- Davis, Alison;
- Xing Julia Zhu;
- Schmidt-Kittler, Oleg;
- Wilson, Doug;
- Wilson, Kevin;
- DiPietro, Lucian;
- Yulian Zhang;
- Brooijmans, Natasja;
- LaBranche, Timothy P.;
- Wozniak, Agnieszka;
- Gebreyohannes, Yemarshet K.;
- Schöffski, Patrick;
- Heinrich, Michael C.;
- DeAngelo, Daniel J.;
- Miller, Stephen
Publication type:
Article
A completely biological "off-the-shelf" arteriovenous graft that recellularizes in baboons.
Published in:
Science Translational Medicine, 2017, v. 9, n. 414, p. 1, doi. 10.1126/scitranslmed.aan4209
By:
- Syedain, Zeeshan H.;
- Graham, Melanie L.;
- Dunn, Ty B.;
- O'Brien, Timothy;
- Johnson, Sandra L.;
- Schumacher, Robert J.;
- Tranquillo, Robert T.
Publication type:
Article
The FcRn inhibitor rozanolixizumab reduces human serum IgG concentration: A randomized phase 1 study.
Published in:
Science Translational Medicine, 2017, v. 9, n. 414, p. 1, doi. 10.1126/scitranslmed.aan1208
By:
- Kiessling, Peter;
- Lledo-Garcia, Rocio;
- Watanabe, Shikiko;
- Langdon, Grant;
- Tran, Diep;
- Bari, Muhammad;
- Christodoulou, Louis;
- Jones, Emma;
- Price, Graham;
- Smith, Bryan;
- Brennan, Frank;
- White, Ian;
- Jolles, Stephen
Publication type:
Article
A role for bacterial urease in gut dysbiosis and Crohn's disease.
Published in:
Science Translational Medicine, 2017, v. 9, n. 416, p. 1, doi. 10.1126/scitranslmed.aah6888
By:
- Ni, Josephine;
- David Shen, Ting-Chin;
- Chen, Eric Z.;
- Bittinger, Kyle;
- Bailey, Aubrey;
- Roggiani, Manuela;
- Sirota-Madi, Alexandra;
- Friedman, Elliot S.;
- Chau, Lillian;
- Lin, Andrew;
- Nissim, Ilana;
- Scott, Justin;
- Lauder, Abigail;
- Hoffmann, Christopher;
- Rivas, Gloriany;
- Albenberg, Lindsey;
- Baldassano, Robert N.;
- Braun, Jonathan;
- Xavier, Ramnik J.;
- Clish, Clary B.
Publication type:
Article
Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with β-blockers.
Published in:
Science Translational Medicine, 2017, v. 9, n. 415, p. 1, doi. 10.1126/scitranslmed.aao4307
By:
- Nilsson, Monique B.;
- Huiying Sun;
- Lixia Diao;
- Pan Tong;
- Diane Liu;
- Lerong Li;
- Youhong Fan;
- Poteete, Alissa;
- Seung-Oe Lim;
- Howells, Kathryn;
- Haddad, Vincent;
- Gomez, Daniel;
- Hai Tran;
- Armaiz Pena, Guillermo;
- Sequist, Lecia V.;
- Yang, James C.;
- Jing Wang;
- Kim, Edward S.;
- Herbst, Roy;
- Lee, J. Jack
Publication type:
Article
Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events.
Published in:
Science Translational Medicine, 2017, v. 9, n. 415, p. 1, doi. 10.1126/scitranslmed.aan0401
By:
- Jun Ishihara;
- Kazuto Fukunaga;
- Ako Ishihara;
- Larsson, Hans M.;
- Potin, Lambert;
- Hosseinchi, Peyman;
- Galliverti, Gabriele;
- Swartz, Melody A.;
- Hubbell, Jeffrey A.
Publication type:
Article
Accumulation of 5-oxoproline in myocardial dysfunction and the protective effects of OPLAH.
Published in:
Science Translational Medicine, 2017, v. 9, n. 415, p. 1, doi. 10.1126/scitranslmed.aam8574
By:
- van der Pol, Atze;
- Gil, Andres;
- Silljé, Herman H. W.;
- Tromp, Jasper;
- Ovchinnikova, Ekaterina S.;
- Vreeswijk-Baudoin, Inge;
- Hoes, Martijn;
- Domian, Ibrahim J.;
- van de Sluis, Bart;
- van Deursen, Jan M.;
- Voors, Adriaan A.;
- van Veldhuisen, Dirk J.;
- van Gilst, Wiek H.;
- Berezikov, Eugene;
- van der Harst, Pim;
- de Boer, Rudolf A.;
- Bischoff, Rainer;
- van der Meer, Peter
Publication type:
Article
Circadian actin dynamics drive rhythmic fibroblast mobilization during wound healing.
Published in:
Science Translational Medicine, 2017, v. 9, n. 415, p. 1, doi. 10.1126/scitranslmed.aal2774
By:
- Hoyle, Nathaniel P.;
- Seinkmane, Estere;
- Putker, Marrit;
- Feeney, Kevin A.;
- Krogager, Toke P.;
- Chesham, Johanna E.;
- Bray, Liam K.;
- Thomas, Justyn M.;
- Dunn, Ken;
- Blaikley, John;
- O'Neill, John S.
Publication type:
Article
RNA binding proteins and the pathological cascade in ALS/FTD neurodegeneration.
Published in:
Science Translational Medicine, 2017, v. 9, n. 415, p. 1, doi. 10.1126/scitranslmed.aah5436
By:
- Daisuke Ito;
- Mami Hatano;
- Norihiro Suzuki
Publication type:
Article
A distinct hematopoietic stem cell population for rapid multilineage engraftment in nonhuman primates.
Published in:
Science Translational Medicine, 2017, v. 9, n. 414, p. 1, doi. 10.1126/scitranslmed.aan1145
By:
- Radtke, Stefan;
- Adair, Jennifer E.;
- Giese, Morgan A.;
- Yan-Yi Chan;
- Norgaard, Zachary K.;
- Enstrom, Mark;
- Haworth, Kevin G.;
- Schefter, Lauren E.;
- Kiem, Hans-Peter
Publication type:
Article
Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors.
Published in:
Science Translational Medicine, 2017, v. 9, n. 414, p. 1, doi. 10.1126/scitranslmed.aam9078
By:
- Henssen, Anton G.;
- Reed, Casie;
- Eileen Jiang;
- Garcia, Heathcliff Dorado;
- von Stebut, Jennifer;
- MacArthur, Ian C.;
- Hundsdoerfer, Patrick;
- Jun Hyun Kim;
- de Stanchina, Elisa;
- Kuwahara, Yasumichi;
- Hosoi, Hajime;
- Ganem, Neil J.;
- Cruz, Filemon Dela;
- Kung, Andrew L.;
- Schulte, Johannes H.;
- Petrini, John H.;
- Kentsis, Alex
Publication type:
Article
Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients.
Published in:
Science Translational Medicine, 2017, v. 9, n. 413, p. 1, doi. 10.1126/scitranslmed.aao4583
By:
- Michelakis, Evangelos D.;
- Gurtu, Vikram;
- Webster, Linda;
- Barnes, Gareth;
- Watson, Geoffrey;
- Howard, Luke;
- Cupitt, John;
- Paterson, Ian;
- Thompson, Richard B.;
- Chow, Kelvin;
- O'Regan, Declan P.;
- Lan Zhao;
- Wharton, John;
- Kiely, David G.;
- Kinnaird, Adam;
- Boukouris, Aristeidis E.;
- White, Chris;
- Nagendran, Jayan;
- Freed, Darren H.;
- Wort, Stephen J.
Publication type:
Article
Overcoming mutational complexity in acute myeloid leukemia by inhibition of critical pathways.
Published in:
Science Translational Medicine, 2017, v. 9, n. 413, p. 1, doi. 10.1126/scitranslmed.aao1214
By:
- Yoriko Saito;
- Yoshiki Mochizuki;
- Ikuko Ogahara;
- Takashi Watanabe;
- Leah Hogdal;
- Shinsuke Takagi;
- Kaori Sato;
- Akiko Kaneko;
- Hiroshi Kajita;
- Naoyuki Uchida;
- Takehiro Fukami;
- Shultz, Leonard D.;
- Shuichi Taniguchi;
- Osamu Ohara;
- Letai, Anthony G.;
- Fumihiko Ishikawa
Publication type:
Article
Evolution-informed forecasting of seasonal influenza A (H3N2).
Published in:
Science Translational Medicine, 2017, v. 9, n. 413, p. 1, doi. 10.1126/scitranslmed.aan5325
By:
- Xiangjun Du;
- King, Aaron A.;
- Woods, Robert J.;
- Pascual, Mercedes
Publication type:
Article
Longitudinal genomic surveillance of MRSA in the UK reveals transmission patterns in hospitals and the community.
Published in:
Science Translational Medicine, 2017, v. 9, n. 413, p. 1, doi. 10.1126/scitranslmed.aak9745
By:
- Coll, Francesc;
- Harrison, Ewan M.;
- Toleman, Michelle S.;
- Reuter, Sandra;
- Raven, Kathy E.;
- Blane, Beth;
- Palmer, Beverley;
- Kappeler, A. Ruth M.;
- Brown, Nicholas M.;
- Török, M. Estée;
- Parkhill, Julian;
- Peacock, Sharon J.
Publication type:
Article
Transplantation of wild-type mouse hematopoietic stem and progenitor cells ameliorates deficits in a mouse model of Friedreich's ataxia.
Published in:
Science Translational Medicine, 2017, v. 9, n. 413, p. 1, doi. 10.1126/scitranslmed.aaj2347
By:
- Rocca, Celine J.;
- Goodman, Spencer M.;
- Dulin, Jennifer N.;
- Haquang, Joseph H.;
- Gertsman, Ilya;
- Blondelle, Jordan;
- Smith, Janell L. M.;
- Heyser, Charles J.;
- Cherqui, Stephanie
Publication type:
Article
Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys.
Published in:
Science Translational Medicine, 2017, v. 9, n. 412, p. 1, doi. 10.1126/scitranslmed.aan8732
By:
- Yumei Xiong;
- Walker, Kenneth;
- Xiaoshan Min;
- Hale, Clarence;
- Thanhvien Tran;
- Komorowski, Renee;
- Yang, Jerry;
- Davda, Jasmine;
- Noi Nuanmanee;
- Kemp, Dao;
- Xiaozhen Wang;
- Hantao Liu;
- Miller, Silke;
- Ki Jeong Lee;
- Zhulun Wang;
- Véniant, Murielle M.
Publication type:
Article
Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia.
Published in:
Science Translational Medicine, 2017, v. 9, n. 412, p. 1, doi. 10.1126/scitranslmed.aan6446
By:
- Ng, Alvin W. T.;
- Song Ling Poon;
- Mi Ni Huang;
- Jing Quan Lim;
- Boot, Arnoud;
- Yu, Willie;
- Yuka Suzuki;
- Saranya Thangaraju;
- Ng, Cedric C. Y.;
- Tan, Patrick;
- See-Tong Pang;
- Hao-Yi Huang;
- Ming-Chin Yu;
- Po-Huang Lee;
- Sen-Yung Hsieh;
- Chang, Alex Y.;
- Bin T. Teh;
- Rozen, Steven G.
Publication type:
Article
ALK is a therapeutic target for lethal sepsis.
Published in:
Science Translational Medicine, 2017, v. 9, n. 412, p. 1, doi. 10.1126/scitranslmed.aan5689
By:
- Ling Zeng;
- Rui Kang;
- Shan Zhu;
- Xiao Wang;
- Lizhi Cao;
- Haichao Wang;
- Billiar, Timothy R.;
- Jianxin Jiang;
- Daolin Tang
Publication type:
Article