Works in Science Translational Medicine, 2025, Vol 17, Issue 781

Results: 6

Orthopedia regulates melanocortin 4 receptor transcription and energy homeostasis.
Published in:
Science Translational Medicine, 2025, v. 17, n. 781, p. 1, doi. 10.1126/scitranslmed.adr6459
By:
- Xu, Baijie;
- Lawler, Katherine;
- Wyler, Steven C.;
- Li, Li;
- Swati;
- Keogh, Julia M.;
- Chen, Xiameng;
- Wan, Rong;
- Almeida, Amanda G.;
- Kirsch, Susan;
- Mountjoy, Kathleen G.;
- Elmquist, Joel K.;
- Farooqi, I. Sadaf;
- Liu, Chen
Publication type:
Article
A population of c-kit<sup>+</sup> IL-17A<sup>+</sup> ILC2s in sputum from individuals with severe asthma supports ILC2 to ILC3 trans-differentiation.
Published in:
Science Translational Medicine, 2025, v. 17, n. 781, p. 1, doi. 10.1126/scitranslmed.ado6649
By:
- Ju, Xiaotian;
- Fard, Nahal Emami;
- Bhalla, Anurag;
- Dvorkin-Gheva, Anna;
- Xiao, Maria;
- Radford, Katherine;
- Zhang, Kayla;
- Ditta, Reina;
- Oliveria, John Paul;
- Paré, Guillaume;
- Mukherjee, Manali;
- Nair, Parameswaran;
- Sehmi, Roma
Publication type:
Article
Epithelial OPA1 links mitochondrial fusion to inflammatory bowel disease.
Published in:
Science Translational Medicine, 2025, v. 17, n. 781, p. 1, doi. 10.1126/scitranslmed.adn8699
By:
- Bao, Li-Li;
- Yu, Yu-Qiang;
- González-Acera, Miguel;
- Patankar, Jay V.;
- Giessl, Andreas;
- Sturm, Gregor;
- Kühl, Anja A.;
- Atreya, Raja;
- Erkert, Lena;
- Gámez-Belmonte, Reyes;
- Krug, Susanne M.;
- Schmid, Benjamin;
- Tripal, Philipp;
- Chiriac, Mircea T.;
- Hildner, Kai;
- Siegmund, Britta;
- Wirtz, Stefan;
- Stürzl, Michael;
- Mohamed Abdou, Mariam;
- Trajanoski, Zlatko
Publication type:
Article
Macrophage-specific in vivo RNA editing promotes phagocytosis and antitumor immunity in mice.
Published in:
Science Translational Medicine, 2025, v. 17, n. 781, p. 1, doi. 10.1126/scitranslmed.adl5800
By:
- Chen, Yuxuan;
- Chen, Xiaohong;
- Zhang, Yao;
- Wang, Meng;
- Yang, Minqi;
- Wang, Ruiji;
- Yan, Xiaojie;
- Shao, Shiyi;
- Xin, Huhu;
- Hu, Qida;
- Wei, Wei;
- Ping, Yuan
Publication type:
Article
Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy.
Published in:
Science Translational Medicine, 2025, v. 17, n. 781, p. 1, doi. 10.1126/scitranslmed.adk3690
By:
- Brandao, Wesley;
- Jain, Nimansha;
- Yin, Zhuoran;
- Kleemann, Kilian L.;
- Carpenter, Madison;
- Bao, Xin;
- Serrano, Javier R.;
- Tycksen, Eric;
- Durao, Ana;
- Barry, Jen-Li;
- Baufeld, Caroline;
- Guneykaya, Dilansu;
- Zhang, Xiaoming;
- Litvinchuk, Alexandra;
- Jiang, Hong;
- Rosenzweig, Neta;
- Pitts, Kristen M.;
- Aronchik, Michael;
- Yahya, Taha;
- Cao, Tian
Publication type:
Article
Gene therapy ameliorates bowel dysmotility and enteric neuron degeneration and extends survival in lysosomal storage disorder mouse models.
Published in:
Science Translational Medicine, 2025, v. 17, n. 781, p. 1, doi. 10.1126/scitranslmed.adj1445
By:
- Ziółkowska, Ewa A.;
- Jansen, Matthew J.;
- Williams, Letitia L.;
- Wang, Sophie H.;
- Eultgen, Elizabeth M.;
- Takahashi, Keigo;
- Le, Steven Q.;
- Nelvagal, Hemanth R.;
- Sharma, Jaiprakash;
- Sardiello, Marco;
- DeBosch, Brian J.;
- Dickson, Patricia I.;
- Anderson, Jessica B.;
- Sax, Sophie E.;
- Wright, Christina M.;
- Bradley, Rebecca P.;
- Whiteman, Ineka T.;
- Makita, Takako;
- Grider, John R.;
- Sands, Mark S.
Publication type:
Article

Works in Science Translational Medicine, 2025, Vol 17, Issue 781

Orthopedia regulates melanocortin 4 receptor transcription and energy homeostasis.

A population of c-kit<sup>+</sup> IL-17A<sup>+</sup> ILC2s in sputum from individuals with severe asthma supports ILC2 to ILC3 trans-differentiation.

Epithelial OPA1 links mitochondrial fusion to inflammatory bowel disease.

Macrophage-specific in vivo RNA editing promotes phagocytosis and antitumor immunity in mice.

Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy.

Gene therapy ameliorates bowel dysmotility and enteric neuron degeneration and extends survival in lysosomal storage disorder mouse models.