Works matching IS 19450877 AND DT 2015 AND VI 8 AND IP 393

Results: 3

Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi.
Published in:
Science Signaling, 2015, v. 8, n. 393, p. 1, doi. 10.1126/scisignal.aab3729
By:
- Housden, Benjamin E.;
- Valvezan, Alexander J.;
- Kelley, Colleen;
- Sopko, Richelle;
- Yanhui Hu;
- Roesel, Charles;
- Shuailiang Lin;
- Buckner, Michael;
- Rong Tao;
- Yilmazel, Bahar;
- Mohr, Stephanie E.;
- Manning, Brendan D.;
- Perrimon, Norbert
Publication type:
Article
Oxidized LDL-bound CD36 recruits an Na<sup>+</sup>/K<sup>+</sup>-ATPase-Lyn complex in macrophages that promotes atherosclerosis.
Published in:
Science Signaling, 2015, v. 8, n. 393, p. 1, doi. 10.1126/scisignal.aaa9623
By:
- Yiliang Chen;
- Kennedy, David J.;
- Ramakrishnan, Devi Prasadh;
- Moua Yang;
- Wenxin Huang;
- Zhichuan Li;
- Zijian Xie;
- Chadwick, Alexandra C.;
- Sahoo, Daisy;
- Silverstein, Roy L.
Publication type:
Article
The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane.
Published in:
Science Signaling, 2015, v. 8, n. 393, p. 1, doi. 10.1126/scisignal.aac6757
By:
- Loregger, Anke;
- Grandl, Martina;
- Mejías-Luque, Raquel;
- Allgäuer, Michael;
- Degenhart, Kathrin;
- Haselmann, Verena;
- Oikonomou, Christina;
- Hatzis, Pantelis;
- Janssen, Klaus-Peter;
- Nitsche, Ulrich;
- Gradl, Dietmar;
- van den Broek, Olaf;
- Destree, Olivier;
- Ulm, Kurt;
- Neumaier, Michael;
- Kalali, Behnam;
- Jung, Andreas;
- Varela, Ignacio;
- Schmid, Roland M.;
- Rad, Roland
Publication type:
Article

Works matching IS 19450877 AND DT 2015 AND VI 8 AND IP 393

Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi.

Oxidized LDL-bound CD36 recruits an Na<sup>+</sup>/K<sup>+</sup>-ATPase-Lyn complex in macrophages that promotes atherosclerosis.

The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane.