Works in mAbs, 2016, Vol 8, Issue 2

Results: 20

Full validation of therapeutic antibody sequences by middle-up mass measurements and middle-down protein sequencing.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 2, p. 318, doi. 10.1080/19420862.2015.1128607

By:

Resemann, Anja;
Jabs, Wolfgang;
Wiechmann, Anja;
Wagner, Elsa;
Colas, Olivier;
Evers, Waltraud;
Belau, Eckhard;
Vorwerg, Lars;
Evans, Catherine;
Beck, Alain;
Suckau, Detlev

Publication type:

Article

Molecular basis of high viscosity in concentrated antibody solutions: Strategies for high concentration drug product development.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 2, p. 216, doi. 10.1080/19420862.2015.1128606

By:

Tomar, Dheeraj S.;
Kumar, Sandeep;
Singh, Satish K.;
Goswami, Sumit;
Li, Li

Publication type:

Article

A comparison of the ability of the human IgG1 allotypes G1m3 and G1m1,17 to stimulate T-cell responses from allotype matched and mismatched donors.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 2, p. 253, doi. 10.1080/19420862.2015.1128605

By:

Webster, Carl I.;
Bryson, Christine J.;
Cloake, Edward A.;
Jones, Tim D.;
Austin, Mark J.;
Karle, Anette C.;
Spindeldreher, Sebastian;
Lowe, David C.;
Baker, Matthew P.

Publication type:

Article

CHO cell production and sequence improvement in the 13C6FR1 anti-Ebola antibody.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 2, p. 347, doi. 10.1080/19420862.2015.1127492

By:

Pettit, Dean K.;
Rogers, Richard S.;
Arthur, Kelly;
Brodsky, Yan;
Clark, Rutilio H.;
Crowell, Chris;
Ennis, Jane;
Gillespie, Alison;
Gillespie, Ron;
Livingston, Brittney;
Nalbandian, Edith;
Pace, Danielle;
Smidt, Pauline;
Pauly, Michael;
Timmons, Ken;
Trentalange, Michael;
Whaley, Kevin J.;
Zeitlin, Larry;
Thomas, James N.

Publication type:

Article

Preclinical studies of a Pro-antibody-drug conjugate designed to selectively target EGFR-overexpressing tumors with improved therapeutic efficacy.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 2, p. 405, doi. 10.1080/19420862.2015.1127491

By:

Yang, Yun;
Guo, Qingcheng;
Chen, Xi;
Zhang, Junjie;
Guo, Huaizu;
Qian, Weizhu;
Hou, Sheng;
Dai, Jianxin;
Li, Bohua;
Guo, Yajun;
Wang, Hao

Publication type:

Article

Antibodies to watch in 2016.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 2, p. 197, doi. 10.1080/19420862.2015.1125583

By:

Reichert, Janice M.

Publication type:

Article

Generation, characterization and preclinical studies of a human anti-L1CAM monoclonal antibody that cross-reacts with rodent L1CAM.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 2, p. 414, doi. 10.1080/19420862.2015.1125067

By:

Cho, Seulki;
Park, Insoo;
Kim, Haejung;
Jeong, Mun Sik;
Lim, Mooney;
Lee, Eung Suk;
Kim, Jin Hong;
Kim, Semi;
Hong, Hyo Jeong

Publication type:

Article

Understanding differences between synthetic and natural antibodies can help improve antibody engineering.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 2, p. 278, doi. 10.1080/19420862.2015.1123365

By:

Burkovitz, Anat;
Ofran, Yanay

Publication type:

Article

Rapid characterization of biotherapeutic proteins by size-exclusion chromatography coupled to native mass spectrometry.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 2, p. 331, doi. 10.1080/19420862.2015.1122150

By:

Haberger, Markus;
Leiss, Michael;
Heidenreich, Anna-Katharina;
Pester, Oxana;
Hafenmair, Georg;
Hook, Michaela;
Bonnington, Lea;
Wegele, Harald;
Haindl, Markus;
Reusch, Dietmar;
Bulau, Patrick

Publication type:

Article

Incomplete target neutralization by the anti-cancer antibody rilotumumab.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 2, p. 246, doi. 10.1080/19420862.2015.1122149

By:

Greenall, Sameer A.;
Adams, Timothy E.;
Johns, Terrance G.

Publication type:

Article

Discovery and characterization of hydroxylysine in recombinant monoclonal antibodies.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 2, p. 371, doi. 10.1080/19420862.2015.1122148

By:

Xie, Qing;
Moore, Benjamin;
Beardsley, Richard L.

Publication type:

Article

Assessing kinetic and epitopic diversity across orthogonal monoclonal antibody generation platforms.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 2, p. 264, doi. 10.1080/19420862.2015.1118596

By:

Abdiche, Yasmina Noubia;
Harriman, Rian;
Deng, Xiaodi;
Yeung, Yik Andy;
Miles, Adam;
Morishige, Winse;
Boustany, Leila;
Zhu, Lei;
Izquierdo, Shelley Mettler;
Harriman, William

Publication type:

Article

VH-VL orientation prediction for antibody humanization candidate selection: A case study.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 2, p. 288, doi. 10.1080/19420862.2015.1117720

By:

Bujotzek, Alexander;
Lipsmeier, Florian;
Harris, Seth F;
Benz, Jörg;
Kuglstatter, Andreas;
Georges, Guy

Publication type:

Article

Glycan analysis of therapeutic glycoproteins.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 2, p. 205, doi. 10.1080/19420862.2015.1117719

By:

Zhang, Lei;
Luo, Shen;
Zhang, Baolin

Publication type:

Article

A sensitive multidimensional method for the detection, characterization, and quantification of trace free drug species in antibody-drug conjugate samples using mass spectral detection.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 2, p. 306, doi. 10.1080/19420862.2015.1116659

By:

Birdsall, Robert E.;
McCarthy, Sean M.;
Janin-Bussat, Marie Claire;
Perez, Michel;
Haeuw, Jean-François;
Chen, Weibin;
Beck, Alain

Publication type:

Article

Identification and characterization of a -1 reading frameshift in the heavy chain constant region of an IgG1 recombinant monoclonal antibody produced in CHO cells.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 2, p. 358, doi. 10.1080/19420862.2015.1116658

By:

Lian, Zhirui;
Wu, Qindong;
Wang, Tongtong

Publication type:

Article

A method to confer Protein L binding ability to any antibody fragment.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 2, p. 379, doi. 10.1080/19420862.2015.1116657

By:

Lakhrif, Zineb;
Pugnière, Martine;
Henriquet, Corinne;
di Tommaso, Anne;
Dimier-Poisson, Isabelle;
Billiald, Philippe;
Juste, Matthieu O.;
Aubrey, Nicolas

Publication type:

Article

Key factors influencing ADME properties of therapeutic proteins: A need for ADME characterization in drug discovery and development.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 2, p. 229, doi. 10.1080/19420862.2015.1115937

By:

Tibbitts, Jay;
Canter, David;
Graff, Ryan;
Smith, Alison;
Khawli, Leslie A.

Publication type:

Article

Development and characterization of human monoclonal antibodies that neutralize multiple TGFβ isoforms.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 2, p. 389, doi. 10.1080/19420862.2015.1115166

By:

Bedinger, Daniel;
Lao, Llewelyn;
Khan, Shireen;
Lee, Steve;
Takeuchi, Toshihiko;
Mirza, Amer M.

Publication type:

Article

Evaluation of a glycoengineered monoclonal antibody via LC-MS analysis in combination with multiple enzymatic digestion.

Published in:

mAbs (1942-0862), 2016, v. 8, n. 2, p. 340, doi. 10.1080/19420862.2015.1113361

By:

Liu, Renpeng;
Giddens, John;
McClung, Colleen M.;
Magnelli, Paula E.;
Wang, Lai-Xi;
Guthrie, Ellen P.

Publication type:

Article