Works matching IS 18607179 AND DT 2021 AND VI 16 AND IP 3

Results: 17

Front Cover: Development of Selective TGR5 Ligands Based on the 5,6,7,8‐Tetrahydro‐5,5,8,8‐tetramethylnaphthalene Skeleton (ChemMedChem 3/2021).

Published in:

ChemMedChem, 2021, v. 16, n. 3, p. 429, doi. 10.1002/cmdc.202100023

By:

Terui, Ryusei;
Yanase, Yuta;
Yokoo, Hidetomo;
Suhara, Yoshitomo;
Makishima, Makoto;
Demizu, Yosuke;
Misawa, Takashi

Publication type:

Article

The Stone Guest: How Does pH Affect Binding Properties of PD‐1/PD‐L1 Inhibitors?

Published in:

ChemMedChem, 2021, v. 16, n. 3, p. 568, doi. 10.1002/cmdc.202000760

By:

Riccio, Alessandra;
Coletti, Alice;
Dolciami, Daniela;
Mammoli, Andrea;
Cerra, Bruno;
Moretti, Sonia;
Gioiello, Antimo;
Ferlin, Simone;
Puxeddu, Efisio;
Macchiarulo, Antonio

Publication type:

Article

1,2,4‐Oxadiazole Topsentin Analogs with Antiproliferative Activity against Pancreatic Cancer Cells, Targeting GSK3β Kinase.

Published in:

ChemMedChem, 2021, v. 16, n. 3, p. 537, doi. 10.1002/cmdc.202000752

By:

Carbone, Daniela;
Parrino, Barbara;
Cascioferro, Stella;
Pecoraro, Camilla;
Giovannetti, Elisa;
Di Sarno, Veronica;
Musella, Simona;
Auriemma, Giulia;
Cirrincione, Girolamo;
Diana, Patrizia

Publication type:

Article

γ‐Non‐Symmetrically Dimasked TriPPPro Prodrugs as Potential Antiviral Agents against HIV.

Published in:

ChemMedChem, 2021, v. 16, n. 3, p. 499, doi. 10.1002/cmdc.202000712

By:

Zhao, Chenglong;
Jia, Xiao;
Schols, Dominique;
Balzarini, Jan;
Meier, Chris

Publication type:

Article

Synthesis and Evaluation of Voltage‐Gated Sodium Channel Blocking Pyrroline Derivatives Endowed with Both Antiarrhythmic and Antioxidant Activities.

Published in:

ChemMedChem, 2021, v. 16, n. 3, p. 578, doi. 10.1002/cmdc.202000692

By:

Carocci, Alessia;
Roselli, Mariagrazia;
Budriesi, Roberta;
Micucci, Matteo;
Desaphy, Jean‐François;
Altamura, Concetta;
Cavalluzzi, Maria Maddalena;
Toma, Maddalena;
Passeri, Giovanna Ilaria;
Milani, Gualtiero;
Lovece, Angelo;
Catalano, Alessia;
Bruno, Claudio;
De Palma, Annalisa;
Corbo, Filomena;
Franchini, Carlo;
Habtemariam, Solomon;
Lentini, Giovanni

Publication type:

Article

An Integrated in silico Approach and in vitro Study for the Discovery of Small‐Molecule USP7 Inhibitors as Potential Cancer Therapies.

Published in:

ChemMedChem, 2021, v. 16, n. 3, p. 555, doi. 10.1002/cmdc.202000675

By:

Kanan, Duaa;
Kanan, Tarek;
Dogan, Berna;
Orhan, Muge Didem;
Avsar, Timucin;
Durdagi, Serdar

Publication type:

Article

Stereoselective Synthesis and Antiallodynic Activity of 3‐Hydroxylated Paroxetines.

Published in:

ChemMedChem, 2021, v. 16, n. 3, p. 472, doi. 10.1002/cmdc.202000674

By:

Chamorro‐Arenas, Delfino;
Salgado‐Moreno, Giovanna;
Martinez‐Mendieta, Liliana;
Quintero, Leticia;
Godínez‐Chaparro, Beatriz;
Sartillo‐Piscil, Fernando

Publication type:

Article

Multitarget Inhibition of Histone Deacetylase (HDAC) and Phosphatidylinositol‐3‐kinase (PI3K): Current and Future Prospects.

Published in:

ChemMedChem, 2021, v. 16, n. 3, p. 448, doi. 10.1002/cmdc.202000643

By:

Rodrigues, Daniel A.;
Pinheiro, Pedro S. M.;
Fraga, Carlos A. M.

Publication type:

Article

Metallocene QACs: The Incorporation of Ferrocene Moieties into monoQAC and bisQAC Structures.

Published in:

ChemMedChem, 2021, v. 16, n. 3, p. 467, doi. 10.1002/cmdc.202000605

By:

Sommers, Kyle J.;
Bentley, Brian S.;
Carden, Robert G.;
Post, Savannah J.;
Allen, Ryan A.;
Kontos, Renee C.;
Black, Jacob W.;
Wuest, William M.;
Minbiole, Kevin P. C.

Publication type:

Article

Tricepyridinium‐inspired QACs yield potent antimicrobials and provide insight into QAC resistance.

Published in:

ChemMedChem, 2021, v. 16, n. 3, p. 463, doi. 10.1002/cmdc.202000604

By:

Garrison, Michelle A.;
Mahoney, Andrew R.;
Wuest, William M.

Publication type:

Article

Evaluation of Water‐Soluble Mannich Base Prodrugs of 2,3,4,5‐Tetrahydroazepino[4,3‐b]indol‐1(6H)‐one as Multitarget‐Directed Agents for Alzheimer's Disease.

Published in:

ChemMedChem, 2021, v. 16, n. 3, p. 589, doi. 10.1002/cmdc.202000583

By:

Purgatorio, Rosa;
Candia, Modesto;
Catto, Marco;
Rullo, Mariagrazia;
Pisani, Leonardo;
Denora, Nunzio;
Carrieri, Antonio;
Nevskaya, Alisa A.;
Voskressensky, Leonid G.;
Altomare, Cosimo D.

Publication type:

Article

Bisubstrate Ether‐Linked Uridine‐Peptide Conjugates as O‐GlcNAc Transferase Inhibitors.

Published in:

ChemMedChem, 2021, v. 16, n. 3, p. 477, doi. 10.1002/cmdc.202000582

By:

Makwana, Vivek;
Ryan, Philip;
Malde, Alpeshkumar K.;
Anoopkumar‐Dukie, Shailendra;
Rudrawar, Santosh

Publication type:

Article

2‐Isoxazolines: A Synthetic and Medicinal Overview.

Published in:

ChemMedChem, 2021, v. 16, n. 3, p. 430, doi. 10.1002/cmdc.202000575

By:

Kumar, Gulshan;
Shankar, Ravi

Publication type:

Article

Development of Selective TGR5 Ligands Based on the 5,6,7,8‐Tetrahydro‐5,5,8,8‐tetramethylnaphthalene Skeleton.

Published in:

ChemMedChem, 2021, v. 16, n. 3, p. 458, doi. 10.1002/cmdc.202000567

By:

Terui, Ryusei;
Yanase, Yuta;
Yokoo, Hidetomo;
Suhara, Yoshitomo;
Makishima, Makoto;
Demizu, Yosuke;
Misawa, Takashi

Publication type:

Article

A Series of Ferulic Acid Amides Reveals Unexpected Peroxiredoxin 1 Inhibitory Activity with in vivo Antidiabetic and Hypolipidemic Effects.

Published in:

ChemMedChem, 2021, v. 16, n. 3, p. 484, doi. 10.1002/cmdc.202000564

By:

Yasmin, Sabina;
Cerchia, Carmen;
Badavath, Vishnu Nayak;
Laghezza, Antonio;
Dal Piaz, Fabrizio;
Mondal, Susanta K.;
Atlı, Özlem;
Baysal, Merve;
Vadivelan, Sankaran;
Shankar, S.;
Siddique, Mohd Usman Mohd;
Pattnaik, Ashok Kumar;
Singh, Ravi Pratap;
Loiodice, Fulvio;
Jayaprakash, Venkatesan;
Lavecchia, Antonio

Publication type:

Article

Synthesis and Pharmacological Evaluation of σ2 Receptor Ligands Based on a 3‐Alkoxyisoxazole Scaffold: Potential Antitumor Effects against Osteosarcoma.

Published in:

ChemMedChem, 2021, v. 16, n. 3, p. 524, doi. 10.1002/cmdc.202000461

By:

Shi, Jun‐Jie;
Jia, Kun‐Hang;
Sun, Hao;
Gunosewoyo, Hendra;
Yang, Fan;
Tang, Jie;
Luo, Jian;
Yu, Li‐Fang

Publication type:

Article

Spermine Derivatives of Indole‐3‐carboxylic Acid, Indole‐3‐acetic Acid and Indole‐3‐acrylic Acid as Gram‐Negative Antibiotic Adjuvants.

Published in:

ChemMedChem, 2021, v. 16, n. 3, p. 513, doi. 10.1002/cmdc.202000359

By:

Cadelis, Melissa M.;
Li, Steven A.;
Bourguet‐Kondracki, Marie‐Lise;
Blanchet, Marine;
Douafer, Hana;
Brunel, Jean Michel;
Copp, Brent R.

Publication type:

Article