Works matching IS 18607179 AND DT 2021 AND VI 16 AND IP 11

Results: 15

Front Cover: E7766, a Macrocycle‐Bridged Stimulator of Interferon Genes (STING) Agonist with Potent Pan‐Genotypic Activity (ChemMedChem 11/2021).
Published in:
ChemMedChem, 2021, v. 16, n. 11, p. 1680, doi. 10.1002/cmdc.202100346
By:
- Kim, Dae‐Shik;
- Endo, Atsushi;
- Fang, Francis G.;
- Huang, Kuan‐Chun;
- Bao, Xingfeng;
- Choi, Hyeong‐wook;
- Majumder, Utpal;
- Shen, Young Y.;
- Mathieu, Steven;
- Zhu, Xiaojie;
- Sanders, Kristen;
- Noland, Thomas;
- Hao, Ming‐Hong;
- Chen, Yu;
- Wang, John Y.;
- Yasui, So;
- TenDyke, Karen;
- Wu, Jiayi;
- Ingersoll, Christy;
- Loiacono, Kara A.
Publication type:
Article
Thiazolidinediones: An In–Depth Study of Their Synthesis and Application to Medicinal Chemistry in the Treatment of Diabetes Mellitus.
Published in:
ChemMedChem, 2021, v. 16, n. 11, p. 1716, doi. 10.1002/cmdc.202100177
By:
- Long, Nathan;
- Le Gresley, Adam;
- Wren, Stephen P.
Publication type:
Article
Hydroxypyridinethione Inhibitors of Human Insulin‐Degrading Enzyme.
Published in:
ChemMedChem, 2021, v. 16, n. 11, p. 1775, doi. 10.1002/cmdc.202100111
By:
- Adamek, Rebecca N.;
- Suire, Caitlin N.;
- Stokes, Ryjul W.;
- Brizuela, Monica K.;
- Cohen, Seth M.;
- Leissring, Malcolm A.
Publication type:
Article
E7766, a Macrocycle‐Bridged Stimulator of Interferon Genes (STING) Agonist with Potent Pan‐Genotypic Activity.
Published in:
ChemMedChem, 2021, v. 16, n. 11, p. 1740, doi. 10.1002/cmdc.202100068
By:
- Kim, Dae‐Shik;
- Endo, Atsushi;
- Fang, Francis G.;
- Huang, Kuan‐Chun;
- Bao, Xingfeng;
- Choi, Hyeong‐wook;
- Majumder, Utpal;
- Shen, Young Y.;
- Mathieu, Steven;
- Zhu, Xiaojie;
- Sanders, Kristen;
- Noland, Thomas;
- Hao, Ming‐Hong;
- Chen, Yu;
- Wang, John Y.;
- Yasui, So;
- TenDyke, Karen;
- Wu, Jiayi;
- Ingersoll, Christy;
- Loiacono, Kara A.
Publication type:
Article
Cyclopentadienyl‐Based Anticancer Drugs: Improvement of Cytotoxic Activity through Functionalisation of the π Ligand.
Published in:
ChemMedChem, 2021, v. 16, n. 11, p. 1804, doi. 10.1002/cmdc.202100060
By:
- Absolonová, Monika;
- Melounková, Lucie;
- Vinklárek, Jaromír;
- Honzíček, Jan;
- Dostál, Libor;
- Mrózek, Ondřej
Publication type:
Article
Using Theory To Extend the Scope of Azobenzene Drugs in Chemotherapy: Novel Combinations for a Specific Delivery.
Published in:
ChemMedChem, 2021, v. 16, n. 11, p. 1764, doi. 10.1002/cmdc.202100046
By:
- Cerón‐Carrasco, José P.;
- Jacquemin, Denis
Publication type:
Article
The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Phenotypic Drug Discovery.
Published in:
ChemMedChem, 2021, v. 16, n. 11, p. 1736, doi. 10.1002/cmdc.202100041
By:
- Quancard, Jean;
- Bach, Anders;
- Cox, Brian;
- Craft, Russell;
- Finsinger, Dirk;
- Guéret, Stéphanie M.;
- Hartung, Ingo V.;
- Laufer, Stefan;
- Messinger, Josef;
- Sbardella, Gianluca;
- Koolman, Hannes F.
Publication type:
Article
Strategies towards Targeting Gαi/s Proteins: Scanning of Protein‐Protein Interaction Sites To Overcome Inaccessibility.
Published in:
ChemMedChem, 2021, v. 16, n. 11, p. 1696, doi. 10.1002/cmdc.202100039
By:
- Nubbemeyer, Britta;
- Pepanian, Anna;
- Paul George, Ajay Abisheck;
- Imhof, Diana
Publication type:
Article
Synthesis of Triphenylethylene‐Naphthalimide Conjugates as topoisomerase‐IIα inhibitor and HSA binder.
Published in:
ChemMedChem, 2021, v. 16, n. 11, p. 1821, doi. 10.1002/cmdc.202100034
By:
- Rani, Sudesh;
- Luxami, Vijay;
- Paul, Kamaldeep
Publication type:
Article
A "Golden Age" for the discovery of new antileishmanial agents: Current status of leishmanicidal gold complexes and prospective targets beyond the trypanothione system.
Published in:
ChemMedChem, 2021, v. 16, n. 11, p. 1681, doi. 10.1002/cmdc.202100022
By:
- Rosa, Leticia B.;
- Aires, Rochanna L.;
- Oliveira, Laiane S.;
- Fontes, Josielle V.;
- Miguel, Danilo C.;
- Abbehausen, Camilla
Publication type:
Article
Drimane Derivatives as the First Examples of Covalent BH3 Mimetics that Target MCL‐1.
Published in:
ChemMedChem, 2021, v. 16, n. 11, p. 1788, doi. 10.1002/cmdc.202100011
By:
- Daressy, Florian;
- Malard, Florian;
- Seguy, Line;
- Guérineau, Vincent;
- Apel, Cécile;
- Dumontet, Vincent;
- Robert, Aude;
- Groo, Anne‐Claire;
- Litaudon, Marc;
- Bignon, Jérôme;
- Desrat, Sandy;
- Malzert‐Fréon, Aurélie;
- Wiels, Joëlle;
- Lescop, Ewen;
- Roussi, Fanny
Publication type:
Article
Oxa Analogues of Nexturastat A Demonstrate Improved HDAC6 Selectivity and Superior Antileukaemia Activity.
Published in:
ChemMedChem, 2021, v. 16, n. 11, p. 1798, doi. 10.1002/cmdc.202001011
By:
- Pflieger, Marc;
- Sönnichsen, Melf;
- Horstick‐Muche, Nadine;
- Yang, Jing;
- Schliehe‐Diecks, Julian;
- Schöler, Andrea;
- Borkhardt, Arndt;
- Hamacher, Alexandra;
- Kassack, Matthias U.;
- Hansen, Finn K.;
- Bhatia, Sanil;
- Kurz, Thomas
Publication type:
Article
The Acid/Base Characterization of Molecules with Epigenetic Activity.
Published in:
ChemMedChem, 2021, v. 16, n. 11, p. 1744, doi. 10.1002/cmdc.202001009
By:
- Santibáñez‐Morán, Marisa G.;
- Medina‐Franco, José L.
Publication type:
Article
Development of a High‐Affinity Antibody‐Binding Peptide for Site‐Specific Modification.
Published in:
ChemMedChem, 2021, v. 16, n. 11, p. 1813, doi. 10.1002/cmdc.202000977
By:
- Muguruma, Kyohei;
- Osawa, Rento;
- Fukuda, Akane;
- Ishikawa, Naoto;
- Fujita, Konomi;
- Taguchi, Akihiro;
- Takayama, Kentaro;
- Taniguchi, Atsuhiko;
- Ito, Yuji;
- Hayashi, Yoshio
Publication type:
Article
Assessment of CYP2C9 Structural Models for Site of Metabolism Prediction.
Published in:
ChemMedChem, 2021, v. 16, n. 11, p. 1754, doi. 10.1002/cmdc.202000964
By:
- Zhang, Xiaoxiao;
- Xu, Minjie;
- Wu, Zengrui;
- Liu, Guixia;
- Tang, Yun;
- Li, Weihua
Publication type:
Article