Works matching IS 18607179 AND DT 2016 AND VI 11 AND IP 8

Results: 27

Phage Selection of Peptide Macrocycles against β-Catenin To Interfere with Wnt Signaling.
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 834, doi. 10.1002/cmdc.201500557
By:
- Bertoldo, Davide;
- Khan, Maola M. G.;
- Dessen, Pierre;
- Held, Werner;
- Huelsken, Joerg;
- Heinis, Christian
Publication type:
Article
Disarming an Electrophilic Warhead: Retaining Potency in Tyrosine Kinase Inhibitor (TKI)-Resistant CML Lines While Circumventing Pharmacokinetic Liabilities.
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 850, doi. 10.1002/cmdc.201600021
By:
- Ali, Ahmed M.;
- Gómez‐Biagi, Rodolfo F.;
- Rosa, David A.;
- Lai, Ping‐Shan;
- Heaton, William L.;
- Park, Ji Sung;
- Eiring, Anna M.;
- Vellore, Nadeem A.;
- de Araujo, Elvin D.;
- Ball, Dan P.;
- Shouksmith, Andrew E.;
- Patel, Ami B.;
- Deininger, Michael W.;
- O'Hare, Thomas;
- Gunning, Patrick T.
Publication type:
Article
Hitting a Moving Target: How Does an N-Methyl Group Impact Biological Activity?
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 881, doi. 10.1002/cmdc.201500572
By:
- Koay, Yen Chin;
- Richardson, Nicole L.;
- Zaiter, Samantha S.;
- Kho, Jessica;
- Nguyen, Sheena Y.;
- Tran, Daniel H.;
- Lee, Ka Wai;
- Buckton, Laura K.;
- McAlpine, Shelli R.
Publication type:
Article
Cyclic and Macrocyclic Peptides as Chemical Tools To Recognise Protein Surfaces and Probe Protein-Protein Interactions.
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 787, doi. 10.1002/cmdc.201500450
By:
- Cardote, Teresa A. F.;
- Ciulli, Alessio
Publication type:
Article
Fragment-Based Protein-Protein Interaction Antagonists of a Viral Dimeric Protease.
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 862, doi. 10.1002/cmdc.201500526
By:
- Gable, Jonathan E.;
- Lee, Gregory M.;
- Acker, Timothy M.;
- Hulce, Kaitlin R.;
- Gonzalez, Eric R.;
- Schweigler, Patrick;
- Melkko, Samu;
- Farady, Christopher J.;
- Craik, Charles S.
Publication type:
Article
Small-Molecule CD4 Mimics Containing Mono-cyclohexyl Moieties as HIV Entry Inhibitors.
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 940, doi. 10.1002/cmdc.201500590
By:
- Ohashi, Nami;
- Harada, Shigeyoshi;
- Mizuguchi, Takaaki;
- Irahara, Yu;
- Yamada, Yuko;
- Kotani, Misato;
- Nomura, Wataru;
- Matsushita, Shuzo;
- Yoshimura, Kazuhisa;
- Tamamura, Hirokazu
Publication type:
Article
Pyrimidine Triazole Thioether Derivatives as Toll-Like Receptor 5 (TLR5)/Flagellin Complex Inhibitors.
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 822, doi. 10.1002/cmdc.201500471
By:
- Yan, Lei;
- Liang, Jiaqi;
- Yao, Chengbo;
- Wu, Peiyao;
- Zeng, Xianfeng;
- Cheng, Kui;
- Yin, Hang
Publication type:
Article
Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A.
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 893, doi. 10.1002/cmdc.201500479
By:
- Patrone, James D.;
- Pelz, Nicholas F.;
- Bates, Brittney S.;
- Souza‐Fagundes, Elaine M.;
- Vangamudi, Bhavatarini;
- Camper, Demarco V.;
- Kuznetsov, Alexey G.;
- Browning, Carrie F.;
- Feldkamp, Michael D.;
- Frank, Andreas O.;
- Gilston, Benjamin A.;
- Olejniczak, Edward T.;
- Rossanese, Olivia W.;
- Waterson, Alex G.;
- Chazin, Walter J.;
- Fesik, Stephen W.
Publication type:
Article
Cover Picture: Pyrimidine Triazole Thioether Derivatives as Toll-Like Receptor 5 (TLR5)/Flagellin Complex Inhibitors (ChemMedChem 8/2016).
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 730, doi. 10.1002/cmdc.201600184
By:
- Yan, Lei;
- Liang, Jiaqi;
- Yao, Chengbo;
- Wu, Peiyao;
- Zeng, Xianfeng;
- Cheng, Kui;
- Yin, Hang
Publication type:
Article
Inside Cover: Disarming an Electrophilic Warhead: Retaining Potency in Tyrosine Kinase Inhibitor (TKI)-Resistant CML Lines While Circumventing Pharmacokinetic Liabilities (ChemMedChem 8/2016).
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 731, doi. 10.1002/cmdc.201600185
By:
- Ali, Ahmed M.;
- Gómez‐Biagi, Rodolfo F.;
- Rosa, David A.;
- Lai, Ping‐Shan;
- Heaton, William L.;
- Park, Ji Sung;
- Eiring, Anna M.;
- Vellore, Nadeem A.;
- de Araujo, Elvin D.;
- Ball, Dan P.;
- Shouksmith, Andrew E.;
- Patel, Ami B.;
- Deininger, Michael W.;
- O'Hare, Thomas;
- Gunning, Patrick T.
Publication type:
Article
Back Cover: High-Throughput Screening (HTS) by NMR Guided Identification of Novel Agents Targeting the Protein Docking Domain of YopH (ChemMedChem 8/2016).
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 947, doi. 10.1002/cmdc.201600186
By:
- Bottini, Angel;
- Wu, Bainan;
- Barile, Elisa;
- De, Surya K.;
- Leone, Marilisa;
- Pellecchia, Maurizio
Publication type:
Article
Targeting Protein-Protein Interactions in the HIF System.
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 773, doi. 10.1002/cmdc.201600012
By:
- Wilkins, Sarah E.;
- Abboud, Martine I.;
- Hancock, Rebecca L.;
- Schofield, Christopher J.
Publication type:
Article
Current Experimental Methods for Characterizing Protein-Protein Interactions.
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 738, doi. 10.1002/cmdc.201500495
By:
- Zhou, Mi;
- Li, Qing;
- Wang, Renxiao
Publication type:
Article
Small-Molecule and Peptide Inhibitors of the Pro-Survival Protein Mcl-1.
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 802, doi. 10.1002/cmdc.201500497
By:
- Beekman, Andrew M.;
- Howell, Lesley A.
Publication type:
Article
High-Throughput Screening (HTS) by NMR Guided Identification of Novel Agents Targeting the Protein Docking Domain of YopH.
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 919, doi. 10.1002/cmdc.201500441
By:
- Bottini, Angel;
- Wu, Bainan;
- Barile, Elisa;
- De, Surya K.;
- Leone, Marilisa;
- Pellecchia, Maurizio
Publication type:
Article
Virtual Screening and Experimental Validation Identify Novel Inhibitors of the Plasmodium falciparum Atg8-Atg3 Protein-Protein Interaction.
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 900, doi. 10.1002/cmdc.201500515
By:
- Hain, Adelaide U. P.;
- Miller, Alexia S.;
- Levitskaya, Jelena;
- Bosch, Jürgen
Publication type:
Article
Understanding Protein-Protein Interactions: Essential Players in (Patho)physiology (Part 2).
Published in:
2016
By:
- Wilson, Andrew J.;
- Gunning, Patrick T.
Publication type:
Editorial
Structural Re-engineering of the α-Helix Mimetic JY-1-106 into Small Molecules: Disruption of the Mcl-1-Bak-BH3 Protein-Protein Interaction with 2,6-Di-Substituted Nicotinates.
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 827, doi. 10.1002/cmdc.201500461
By:
- Drennen, Brandon;
- Scheenstra, Jacob A.;
- Yap, Jeremy L.;
- Chen, Lijia;
- Lanning, Maryanna E.;
- Roth, Braden M.;
- Wilder, Paul T.;
- Fletcher, Steven
Publication type:
Article
Combined Use of Oligopeptides, Fragment Libraries, and Natural Compounds: A Comprehensive Approach To Sample the Druggability of Vascular Endothelial Growth Factor.
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 928, doi. 10.1002/cmdc.201500467
By:
- Bayó‐Puxan, Núria;
- Rodríguez‐Mias, Ricard;
- Goldflam, Michael;
- Kotev, Martin;
- Ciudad, Sonia;
- Hipolito, Christopher J.;
- Varese, Monica;
- Suga, Hiroaki;
- Campos‐Olivas, Ramón;
- Barril, Xavier;
- Guallar, Víctor;
- Teixidó, Meritxell;
- García, Jesús;
- Giralt, Ernest
Publication type:
Article
Effect of N-Terminal Acylation on the Activity of Myostatin Inhibitory Peptides.
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 845, doi. 10.1002/cmdc.201500533
By:
- Takayama, Kentaro;
- Nakamura, Akari;
- Rentier, Cédric;
- Mino, Yusaku;
- Asari, Tomo;
- Saga, Yusuke;
- Taguchi, Akihiro;
- Yakushiji, Fumika;
- Hayashi, Yoshio
Publication type:
Article
Spotlights on our sister journals: ChemMedChem 8/2016.
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 734, doi. 10.1002/cmdc.201680813
Publication type:
Article
Inhibitors of Ras-SOS Interactions.
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 814, doi. 10.1002/cmdc.201500481
By:
- Lu, Shaoyong;
- Jang, Hyunbum;
- Zhang, Jian;
- Nussinov, Ruth
Publication type:
Article
STAT3-Interacting Proteins as Modulators of Transcription Factor Function: Implications to Targeted Cancer Therapy.
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 795, doi. 10.1002/cmdc.201500482
By:
- Yeh, Jennifer E.;
- Frank, David A.
Publication type:
Article
Structure-Activity Studies of Bis- O-Arylglycolamides: Inhibitors of the Integrated Stress Response.
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 870, doi. 10.1002/cmdc.201500483
By:
- Hearn, Brian R.;
- Jaishankar, Priyadarshini;
- Sidrauski, Carmela;
- Tsai, Jordan C.;
- Vedantham, Punitha;
- Fontaine, Shaun D.;
- Walter, Peter;
- Renslo, Adam R.
Publication type:
Article
Small-Molecule Stabilization of the 14-3-3/Gab2 Protein-Protein Interaction (PPI) Interface.
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 911, doi. 10.1002/cmdc.201500484
By:
- Bier, David;
- Bartel, Maria;
- Sies, Katharina;
- Halbach, Sebastian;
- Higuchi, Yusuke;
- Haranosono, Yu;
- Brummer, Tilman;
- Kato, Nobuo;
- Ottmann, Christian
Publication type:
Article
How To Design a Successful p53-MDM2/X Interaction Inhibitor: A Thorough Overview Based on Crystal Structures.
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 757, doi. 10.1002/cmdc.201500487
By:
- Estrada‐Ortiz, Natalia;
- Neochoritis, Constantinos G.;
- Dömling, Alexander
Publication type:
Article
Identification of Small-Molecule Inhibitors of the Antiapoptotic Protein Myeloid Cell Leukaemia-1 (Mcl-1).
Published in:
ChemMedChem, 2016, v. 11, n. 8, p. 840, doi. 10.1002/cmdc.201500488
By:
- Beekman, Andrew M.;
- O'Connell, Maria A.;
- Howell, Lesley A.
Publication type:
Article