Works matching IS 18607179 AND DT 2016 AND VI 11 AND IP 8

Results: 27

Phage Selection of Peptide Macrocycles against β-Catenin To Interfere with Wnt Signaling.

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 834, doi. 10.1002/cmdc.201500557

By:

Bertoldo, Davide;
Khan, Maola M. G.;
Dessen, Pierre;
Held, Werner;
Huelsken, Joerg;
Heinis, Christian

Publication type:

Article

Disarming an Electrophilic Warhead: Retaining Potency in Tyrosine Kinase Inhibitor (TKI)-Resistant CML Lines While Circumventing Pharmacokinetic Liabilities.

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 850, doi. 10.1002/cmdc.201600021

By:

Ali, Ahmed M.;
Gómez‐Biagi, Rodolfo F.;
Rosa, David A.;
Lai, Ping‐Shan;
Heaton, William L.;
Park, Ji Sung;
Eiring, Anna M.;
Vellore, Nadeem A.;
de Araujo, Elvin D.;
Ball, Dan P.;
Shouksmith, Andrew E.;
Patel, Ami B.;
Deininger, Michael W.;
O'Hare, Thomas;
Gunning, Patrick T.

Publication type:

Article

Hitting a Moving Target: How Does an N-Methyl Group Impact Biological Activity?

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 881, doi. 10.1002/cmdc.201500572

By:

Koay, Yen Chin;
Richardson, Nicole L.;
Zaiter, Samantha S.;
Kho, Jessica;
Nguyen, Sheena Y.;
Tran, Daniel H.;
Lee, Ka Wai;
Buckton, Laura K.;
McAlpine, Shelli R.

Publication type:

Article

Cyclic and Macrocyclic Peptides as Chemical Tools To Recognise Protein Surfaces and Probe Protein-Protein Interactions.

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 787, doi. 10.1002/cmdc.201500450

By:

Cardote, Teresa A. F.;
Ciulli, Alessio

Publication type:

Article

Fragment-Based Protein-Protein Interaction Antagonists of a Viral Dimeric Protease.

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 862, doi. 10.1002/cmdc.201500526

By:

Gable, Jonathan E.;
Lee, Gregory M.;
Acker, Timothy M.;
Hulce, Kaitlin R.;
Gonzalez, Eric R.;
Schweigler, Patrick;
Melkko, Samu;
Farady, Christopher J.;
Craik, Charles S.

Publication type:

Article

Small-Molecule CD4 Mimics Containing Mono-cyclohexyl Moieties as HIV Entry Inhibitors.

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 940, doi. 10.1002/cmdc.201500590

By:

Ohashi, Nami;
Harada, Shigeyoshi;
Mizuguchi, Takaaki;
Irahara, Yu;
Yamada, Yuko;
Kotani, Misato;
Nomura, Wataru;
Matsushita, Shuzo;
Yoshimura, Kazuhisa;
Tamamura, Hirokazu

Publication type:

Article

Pyrimidine Triazole Thioether Derivatives as Toll-Like Receptor 5 (TLR5)/Flagellin Complex Inhibitors.

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 822, doi. 10.1002/cmdc.201500471

By:

Yan, Lei;
Liang, Jiaqi;
Yao, Chengbo;
Wu, Peiyao;
Zeng, Xianfeng;
Cheng, Kui;
Yin, Hang

Publication type:

Article

Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A.

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 893, doi. 10.1002/cmdc.201500479

By:

Patrone, James D.;
Pelz, Nicholas F.;
Bates, Brittney S.;
Souza‐Fagundes, Elaine M.;
Vangamudi, Bhavatarini;
Camper, Demarco V.;
Kuznetsov, Alexey G.;
Browning, Carrie F.;
Feldkamp, Michael D.;
Frank, Andreas O.;
Gilston, Benjamin A.;
Olejniczak, Edward T.;
Rossanese, Olivia W.;
Waterson, Alex G.;
Chazin, Walter J.;
Fesik, Stephen W.

Publication type:

Article

Cover Picture: Pyrimidine Triazole Thioether Derivatives as Toll-Like Receptor 5 (TLR5)/Flagellin Complex Inhibitors (ChemMedChem 8/2016).

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 730, doi. 10.1002/cmdc.201600184

By:

Yan, Lei;
Liang, Jiaqi;
Yao, Chengbo;
Wu, Peiyao;
Zeng, Xianfeng;
Cheng, Kui;
Yin, Hang

Publication type:

Article

Inside Cover: Disarming an Electrophilic Warhead: Retaining Potency in Tyrosine Kinase Inhibitor (TKI)-Resistant CML Lines While Circumventing Pharmacokinetic Liabilities (ChemMedChem 8/2016).

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 731, doi. 10.1002/cmdc.201600185

By:

Ali, Ahmed M.;
Gómez‐Biagi, Rodolfo F.;
Rosa, David A.;
Lai, Ping‐Shan;
Heaton, William L.;
Park, Ji Sung;
Eiring, Anna M.;
Vellore, Nadeem A.;
de Araujo, Elvin D.;
Ball, Dan P.;
Shouksmith, Andrew E.;
Patel, Ami B.;
Deininger, Michael W.;
O'Hare, Thomas;
Gunning, Patrick T.

Publication type:

Article

Back Cover: High-Throughput Screening (HTS) by NMR Guided Identification of Novel Agents Targeting the Protein Docking Domain of YopH (ChemMedChem 8/2016).

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 947, doi. 10.1002/cmdc.201600186

By:

Bottini, Angel;
Wu, Bainan;
Barile, Elisa;
De, Surya K.;
Leone, Marilisa;
Pellecchia, Maurizio

Publication type:

Article

Targeting Protein-Protein Interactions in the HIF System.

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 773, doi. 10.1002/cmdc.201600012

By:

Wilkins, Sarah E.;
Abboud, Martine I.;
Hancock, Rebecca L.;
Schofield, Christopher J.

Publication type:

Article

Current Experimental Methods for Characterizing Protein-Protein Interactions.

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 738, doi. 10.1002/cmdc.201500495

By:

Zhou, Mi;
Li, Qing;
Wang, Renxiao

Publication type:

Article

Small-Molecule and Peptide Inhibitors of the Pro-Survival Protein Mcl-1.

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 802, doi. 10.1002/cmdc.201500497

By:

Beekman, Andrew M.;
Howell, Lesley A.

Publication type:

Article

High-Throughput Screening (HTS) by NMR Guided Identification of Novel Agents Targeting the Protein Docking Domain of YopH.

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 919, doi. 10.1002/cmdc.201500441

By:

Bottini, Angel;
Wu, Bainan;
Barile, Elisa;
De, Surya K.;
Leone, Marilisa;
Pellecchia, Maurizio

Publication type:

Article

Virtual Screening and Experimental Validation Identify Novel Inhibitors of the Plasmodium falciparum Atg8-Atg3 Protein-Protein Interaction.

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 900, doi. 10.1002/cmdc.201500515

By:

Hain, Adelaide U. P.;
Miller, Alexia S.;
Levitskaya, Jelena;
Bosch, Jürgen

Publication type:

Article

Understanding Protein-Protein Interactions: Essential Players in (Patho)physiology (Part 2).

Published in:

2016

By:

Wilson, Andrew J.;
Gunning, Patrick T.

Publication type:

Editorial

Structural Re-engineering of the α-Helix Mimetic JY-1-106 into Small Molecules: Disruption of the Mcl-1-Bak-BH3 Protein-Protein Interaction with 2,6-Di-Substituted Nicotinates.

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 827, doi. 10.1002/cmdc.201500461

By:

Drennen, Brandon;
Scheenstra, Jacob A.;
Yap, Jeremy L.;
Chen, Lijia;
Lanning, Maryanna E.;
Roth, Braden M.;
Wilder, Paul T.;
Fletcher, Steven

Publication type:

Article

Combined Use of Oligopeptides, Fragment Libraries, and Natural Compounds: A Comprehensive Approach To Sample the Druggability of Vascular Endothelial Growth Factor.

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 928, doi. 10.1002/cmdc.201500467

By:

Bayó‐Puxan, Núria;
Rodríguez‐Mias, Ricard;
Goldflam, Michael;
Kotev, Martin;
Ciudad, Sonia;
Hipolito, Christopher J.;
Varese, Monica;
Suga, Hiroaki;
Campos‐Olivas, Ramón;
Barril, Xavier;
Guallar, Víctor;
Teixidó, Meritxell;
García, Jesús;
Giralt, Ernest

Publication type:

Article

Effect of N-Terminal Acylation on the Activity of Myostatin Inhibitory Peptides.

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 845, doi. 10.1002/cmdc.201500533

By:

Takayama, Kentaro;
Nakamura, Akari;
Rentier, Cédric;
Mino, Yusaku;
Asari, Tomo;
Saga, Yusuke;
Taguchi, Akihiro;
Yakushiji, Fumika;
Hayashi, Yoshio

Publication type:

Article

Spotlights on our sister journals: ChemMedChem 8/2016.

Published in:: ChemMedChem, 2016, v. 11, n. 8, p. 734, doi. 10.1002/cmdc.201680813
Publication type:: Article

Inhibitors of Ras-SOS Interactions.

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 814, doi. 10.1002/cmdc.201500481

By:

Lu, Shaoyong;
Jang, Hyunbum;
Zhang, Jian;
Nussinov, Ruth

Publication type:

Article

STAT3-Interacting Proteins as Modulators of Transcription Factor Function: Implications to Targeted Cancer Therapy.

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 795, doi. 10.1002/cmdc.201500482

By:

Yeh, Jennifer E.;
Frank, David A.

Publication type:

Article

Structure-Activity Studies of Bis- O-Arylglycolamides: Inhibitors of the Integrated Stress Response.

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 870, doi. 10.1002/cmdc.201500483

By:

Hearn, Brian R.;
Jaishankar, Priyadarshini;
Sidrauski, Carmela;
Tsai, Jordan C.;
Vedantham, Punitha;
Fontaine, Shaun D.;
Walter, Peter;
Renslo, Adam R.

Publication type:

Article

Small-Molecule Stabilization of the 14-3-3/Gab2 Protein-Protein Interaction (PPI) Interface.

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 911, doi. 10.1002/cmdc.201500484

By:

Bier, David;
Bartel, Maria;
Sies, Katharina;
Halbach, Sebastian;
Higuchi, Yusuke;
Haranosono, Yu;
Brummer, Tilman;
Kato, Nobuo;
Ottmann, Christian

Publication type:

Article

How To Design a Successful p53-MDM2/X Interaction Inhibitor: A Thorough Overview Based on Crystal Structures.

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 757, doi. 10.1002/cmdc.201500487

By:

Estrada‐Ortiz, Natalia;
Neochoritis, Constantinos G.;
Dömling, Alexander

Publication type:

Article

Identification of Small-Molecule Inhibitors of the Antiapoptotic Protein Myeloid Cell Leukaemia-1 (Mcl-1).

Published in:

ChemMedChem, 2016, v. 11, n. 8, p. 840, doi. 10.1002/cmdc.201500488

By:

Beekman, Andrew M.;
O'Connell, Maria A.;
Howell, Lesley A.

Publication type:

Article