Works matching IS 18607179 AND DT 2016 AND VI 11 AND IP 12

Results: 25

Design, Synthesis and in vitro Evaluation of Indolotacrine Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease.
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1264, doi. 10.1002/cmdc.201500383
By:
- Benek, Ondrej;
- Soukup, Ondrej;
- Pasdiorova, Marketa;
- Hroch, Lukas;
- Sepsova, Vendula;
- Jost, Petr;
- Hrabinova, Martina;
- Jun, Daniel;
- Kuca, Kamil;
- Zala, Dominykas;
- Ramsay, Rona R.;
- Marco‐Contelles, José;
- Musilek, Kamil
Publication type:
Article
Potent and Selective Inhibitors of Trypanosoma cruzi Triosephosphate Isomerase with Concomitant Inhibition of Cruzipain: Inhibition of Parasite Growth through Multitarget Activity.
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1328, doi. 10.1002/cmdc.201500385
By:
- Aguilera, Elena;
- Varela, Javier;
- Birriel, Estefanía;
- Serna, Elva;
- Torres, Susana;
- Yaluff, Gloria;
- de Bilbao, Ninfa Vera;
- Aguirre‐López, Beatriz;
- Cabrera, Nallely;
- Díaz Mazariegos, Selma;
- de Gómez‐Puyou, Marieta Tuena;
- Gómez‐Puyou, Armando;
- Pérez‐Montfort, Ruy;
- Minini, Lucia;
- Merlino, Alicia;
- Cerecetto, Hugo;
- González, Mercedes;
- Alvarez, Guzmán
Publication type:
Article
Development and Application of a Virtual Screening Protocol for the Identification of Multitarget Fragments.
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1259, doi. 10.1002/cmdc.201500521
By:
- Bottegoni, Giovanni;
- Veronesi, Marina;
- Bisignano, Paola;
- Kacker, Puneet;
- Favia, Angelo D.;
- Cavalli, Andrea
Publication type:
Article
Metabolism-Activated Multitargeting (MAMUT): An Innovative Multitargeting Approach to Drug Design and Development.
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1197, doi. 10.1002/cmdc.201500406
By:
- Mátyus, Péter;
- Chai, Christina L. L.
Publication type:
Article
Cover Picture: Aminobenzimidazoles and Structural Isomers as Templates for Dual-Acting Butyrylcholinesterase Inhibitors and hCB2R Ligands To Combat Neurodegenerative Disorders (ChemMedChem 12/2016).
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1188, doi. 10.1002/cmdc.201600285
By:
- Dolles, Dominik;
- Nimczick, Martin;
- Scheiner, Matthias;
- Ramler, Jacqueline;
- Stadtmüller, Patricia;
- Sawatzky, Edgar;
- Drakopoulos, Antonios;
- Sotriffer, Christoph;
- Wittmann, Hans‐Joachim;
- Strasser, Andrea;
- Decker, Michael
Publication type:
Article
Inside Cover: Development and Application of a Virtual Screening Protocol for the Identification of Multitarget Fragments (ChemMedChem 12/2016).
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1189, doi. 10.1002/cmdc.201600286
By:
- Bottegoni, Giovanni;
- Veronesi, Marina;
- Bisignano, Paola;
- Kacker, Puneet;
- Favia, Angelo D.;
- Cavalli, Andrea
Publication type:
Article
Back Cover: Potent and Selective Inhibitors of Trypanosoma cruzi Triosephosphate Isomerase with Concomitant Inhibition of Cruzipain: Inhibition of Parasite Growth through Multitarget Activity (ChemMedChem 12/2016).
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1395, doi. 10.1002/cmdc.201600287
By:
- Aguilera, Elena;
- Varela, Javier;
- Birriel, Estefanía;
- Serna, Elva;
- Torres, Susana;
- Yaluff, Gloria;
- de Bilbao, Ninfa Vera;
- Aguirre‐López, Beatriz;
- Cabrera, Nallely;
- Díaz Mazariegos, Selma;
- de Gómez‐Puyou, Marieta Tuena;
- Gómez‐Puyou, Armando;
- Pérez‐Montfort, Ruy;
- Minini, Lucia;
- Merlino, Alicia;
- Cerecetto, Hugo;
- González, Mercedes;
- Alvarez, Guzmán
Publication type:
Article
Multitarget Drug Discovery and Polypharmacology.
Published in:
2016
By:
- Bolognesi, Maria Laura;
- Cavalli, Andrea
Publication type:
Editorial
Subtle Structural Differences Trigger Inhibitory Activity of Propafenone Analogues at the Two Polyspecific ABC Transporters: P-Glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP).
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1380, doi. 10.1002/cmdc.201500592
By:
- Schwarz, Theresa;
- Montanari, Floriane;
- Cseke, Anna;
- Wlcek, Katrin;
- Visvader, Lene;
- Palme, Sarah;
- Chiba, Peter;
- Kuchler, Karl;
- Urban, Ernst;
- Ecker, Gerhard F.
Publication type:
Article
Fighting Cancer with Transition Metal Complexes: From Naked DNA to Protein and Chromatin Targeting Strategies.
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1199, doi. 10.1002/cmdc.201500478
By:
- Palermo, Giulia;
- Magistrato, Alessandra;
- Riedel, Tina;
- von Erlach, Thibaud;
- Davey, Curt A.;
- Dyson, Paul J.;
- Rothlisberger, Ursula
Publication type:
Article
Nature-Inspired Multifunctional Ligands: Focusing on Amyloid-Based Molecular Mechanisms of Alzheimer's Disease.
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1309, doi. 10.1002/cmdc.201500422
By:
- Simoni, Elena;
- Serafini, Melania M.;
- Bartolini, Manuela;
- Caporaso, Roberta;
- Pinto, Antonella;
- Necchi, Daniela;
- Fiori, Jessica;
- Andrisano, Vincenza;
- Minarini, Anna;
- Lanni, Cristina;
- Rosini, Michela
Publication type:
Article
Polypharmacology in Drug Development: A Minireview of Current Technologies.
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1211, doi. 10.1002/cmdc.201600067
By:
- Tan, Zhi;
- Chaudhai, Rajan;
- Zhang, Shuxing
Publication type:
Article
Novel 8-Hydroxyquinoline Derivatives as Multitarget Compounds for the Treatment of Alzheimer′s Disease.
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1284, doi. 10.1002/cmdc.201600014
By:
- Prati, Federica;
- Bergamini, Christian;
- Fato, Romana;
- Soukup, Ondrej;
- Korabecny, Jan;
- Andrisano, Vincenza;
- Bartolini, Manuela;
- Bolognesi, Maria Laura
Publication type:
Article
Spotlights on our sister journals: ChemMedChem 12/2016.
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1193, doi. 10.1002/cmdc.201681213
Publication type:
Article
Concepts and Molecular Aspects in the Polypharmacology of PARP-1 Inhibitors.
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1219, doi. 10.1002/cmdc.201500391
By:
- Passeri, Daniela;
- Camaioni, Emidio;
- Liscio, Paride;
- Sabbatini, Paola;
- Ferri, Martina;
- Carotti, Andrea;
- Giacchè, Nicola;
- Pellicciari, Roberto;
- Gioiello, Antimo;
- Macchiarulo, Antonio
Publication type:
Article
Multitarget Strategy to Address Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and Computational Studies of Coumarin-Based Derivatives.
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1296, doi. 10.1002/cmdc.201500392
By:
- Montanari, Serena;
- Bartolini, Manuela;
- Neviani, Paolo;
- Belluti, Federica;
- Gobbi, Silvia;
- Pruccoli, Letizia;
- Tarozzi, Andrea;
- Falchi, Federico;
- Andrisano, Vincenza;
- Miszta, Przemysław;
- Cavalli, Andrea;
- Filipek, Sławomir;
- Bisi, Alessandra;
- Rampa, Angela
Publication type:
Article
Multitarget Drugs: an Epigenetic Epiphany.
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1227, doi. 10.1002/cmdc.201500394
By:
- Ganesan, A.
Publication type:
Article
A Double Whammy: Targeting Both Fatty Acid Amide Hydrolase (FAAH) and Cyclooxygenase (COX) To Treat Pain and Inflammation.
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1242, doi. 10.1002/cmdc.201500395
By:
- Scarpelli, Rita;
- Sasso, Oscar;
- Piomelli, Daniele
Publication type:
Article
Light-Tunable Generation of Singlet Oxygen and Nitric Oxide with a Bichromophoric Molecular Hybrid: a Bimodal Approach to Killing Cancer Cells.
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1371, doi. 10.1002/cmdc.201500396
By:
- Fraix, Aurore;
- Blangetti, Marco;
- Guglielmo, Stefano;
- Lazzarato, Loretta;
- Marino, Nino;
- Cardile, Venera;
- Graziano, Adriana C. E.;
- Manet, Ilse;
- Fruttero, Roberta;
- Gasco, Alberto;
- Sortino, Salvatore
Publication type:
Article
Systematic Assessment of Molecular Selectivity at the Level of Targets, Bioactive Compounds, and Structural Analogues.
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1362, doi. 10.1002/cmdc.201500340
By:
- Hu, Ye;
- Bajorath, Jürgen
Publication type:
Article
Predicting Molecular Targets for Small-Molecule Drugs with a Ligand-Based Interaction Fingerprint Approach.
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1352, doi. 10.1002/cmdc.201500228
By:
- Cao, Ran;
- Wang, Yanli
Publication type:
Article
Synthesis and Biological Assessment of Racemic Benzochromenopyrimidinimines as Antioxidant, Cholinesterase, and Aβ1−42 Aggregation Inhibitors for Alzheimer's Disease Therapy.
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1318, doi. 10.1002/cmdc.201500539
By:
- Dgachi, Youssef;
- Ismaili, Lhassane;
- Knez, Damijan;
- Benchekroun, Mohamed;
- Martin, Hélène;
- Szałaj, Natalia;
- Wehle, Sarah;
- Bautista‐Aguilera, Oscar M.;
- Luzet, Vincent;
- Bonnet, Alexandre;
- Malawska, Barbara;
- Gobec, Stanislav;
- Chioua, Mourad;
- Decker, Michael;
- Chabchoub, Fakher;
- Marco‐Contelles, José
Publication type:
Article
Aminobenzimidazoles and Structural Isomers as Templates for Dual-Acting Butyrylcholinesterase Inhibitors and hCB2R Ligands To Combat Neurodegenerative Disorders.
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1270, doi. 10.1002/cmdc.201500418
By:
- Dolles, Dominik;
- Nimczick, Martin;
- Scheiner, Matthias;
- Ramler, Jacqueline;
- Stadtmüller, Patricia;
- Sawatzky, Edgar;
- Drakopoulos, Antonios;
- Sotriffer, Christoph;
- Wittmann, Hans‐Joachim;
- Strasser, Andrea;
- Decker, Michael
Publication type:
Article
Redox Polypharmacology as an Emerging Strategy to Combat Malarial Parasites.
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1339, doi. 10.1002/cmdc.201600009
By:
- Sidorov, Pavel;
- Desta, Israel;
- Chessé, Matthieu;
- Horvath, Dragos;
- Marcou, Gilles;
- Varnek, Alexandre;
- Davioud‐Charvet, Elisabeth;
- Elhabiri, Mourad
Publication type:
Article
The Molecular Basis for Dual Fatty Acid Amide Hydrolase (FAAH)/Cyclooxygenase (COX) Inhibition.
Published in:
ChemMedChem, 2016, v. 11, n. 12, p. 1252, doi. 10.1002/cmdc.201500507
By:
- Palermo, Giulia;
- Favia, Angelo D.;
- Convertino, Marino;
- De Vivo, Marco
Publication type:
Article

Works matching IS 18607179 AND DT 2016 AND VI 11 AND IP 12

Design, Synthesis and in vitro Evaluation of Indolotacrine Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease.

Potent and Selective Inhibitors of Trypanosoma cruzi Triosephosphate Isomerase with Concomitant Inhibition of Cruzipain: Inhibition of Parasite Growth through Multitarget Activity.

Development and Application of a Virtual Screening Protocol for the Identification of Multitarget Fragments.

Metabolism-Activated Multitargeting (MAMUT): An Innovative Multitargeting Approach to Drug Design and Development.

Cover Picture: Aminobenzimidazoles and Structural Isomers as Templates for Dual-Acting Butyrylcholinesterase Inhibitors and hCB<sub>2</sub>R Ligands To Combat Neurodegenerative Disorders (ChemMedChem 12/2016).

Inside Cover: Development and Application of a Virtual Screening Protocol for the Identification of Multitarget Fragments (ChemMedChem 12/2016).

Back Cover: Potent and Selective Inhibitors of Trypanosoma cruzi Triosephosphate Isomerase with Concomitant Inhibition of Cruzipain: Inhibition of Parasite Growth through Multitarget Activity (ChemMedChem 12/2016).

Multitarget Drug Discovery and Polypharmacology.

Subtle Structural Differences Trigger Inhibitory Activity of Propafenone Analogues at the Two Polyspecific ABC Transporters: P-Glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP).

Fighting Cancer with Transition Metal Complexes: From Naked DNA to Protein and Chromatin Targeting Strategies.

Nature-Inspired Multifunctional Ligands: Focusing on Amyloid-Based Molecular Mechanisms of Alzheimer's Disease.

Polypharmacology in Drug Development: A Minireview of Current Technologies.

Novel 8-Hydroxyquinoline Derivatives as Multitarget Compounds for the Treatment of Alzheimer′s Disease.

Spotlights on our sister journals: ChemMedChem 12/2016.

Concepts and Molecular Aspects in the Polypharmacology of PARP-1 Inhibitors.

Multitarget Strategy to Address Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and Computational Studies of Coumarin-Based Derivatives.

Multitarget Drugs: an Epigenetic Epiphany.

A Double Whammy: Targeting Both Fatty Acid Amide Hydrolase (FAAH) and Cyclooxygenase (COX) To Treat Pain and Inflammation.

Light-Tunable Generation of Singlet Oxygen and Nitric Oxide with a Bichromophoric Molecular Hybrid: a Bimodal Approach to Killing Cancer Cells.

Systematic Assessment of Molecular Selectivity at the Level of Targets, Bioactive Compounds, and Structural Analogues.

Predicting Molecular Targets for Small-Molecule Drugs with a Ligand-Based Interaction Fingerprint Approach.

Synthesis and Biological Assessment of Racemic Benzochromenopyrimidinimines as Antioxidant, Cholinesterase, and Aβ<sub>1−42</sub> Aggregation Inhibitors for Alzheimer's Disease Therapy.

Aminobenzimidazoles and Structural Isomers as Templates for Dual-Acting Butyrylcholinesterase Inhibitors and hCB<sub>2</sub>R Ligands To Combat Neurodegenerative Disorders.

Redox Polypharmacology as an Emerging Strategy to Combat Malarial Parasites.

The Molecular Basis for Dual Fatty Acid Amide Hydrolase (FAAH)/Cyclooxygenase (COX) Inhibition.