Works matching IS 18607179 AND DT 2015 AND VI 10 AND IP 7

Results: 23

Novel Furin Inhibitors with Potent Anti-infectious Activity.

Published in:

ChemMedChem, 2015, v. 10, n. 7, p. 1218, doi. 10.1002/cmdc.201500103

By:

Hardes, Kornelia;
Becker, Gero L.;
Lu, Yinghui;
Dahms, Sven O.;
Köhler, Susanne;
Beyer, Wolfgang;
Sandvig, Kirsten;
Yamamoto, Hiroyuki;
Lindberg, Iris;
Walz, Lisa;
von Messling, Veronika;
Than, Manuel E.;
Garten, Wolfgang;
Steinmetzer, Torsten

Publication type:

Article

Cover Picture: Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases (ChemMedChem 7/2015).

Published in:

ChemMedChem, 2015, v. 10, n. 7, p. 1117, doi. 10.1002/cmdc.201590019

By:

von Nussbaum, Franz;
Li, Volkhart M.‐J.;
Allerheiligen, Swen;
Anlauf, Sonja;
Bärfacker, Lars;
Bechem, Martin;
Delbeck, Martina;
Fitzgerald, Mary F.;
Gerisch, Michael;
Gielen‐Haertwig, Heike;
Haning, Helmut;
Karthaus, Dagmar;
Lang, Dieter;
Lustig, Klemens;
Meibom, Daniel;
Mittendorf, Joachim;
Rosentreter, Ulrich;
Schäfer, Martina;
Schäfer, Stefan;
Schamberger, Jens

Publication type:

Article

Antifungals: From Genomics to Resistance and the Development of Novel Agents. Edited by Alix T. Coste and Patrick Vandeputte.

Published in:

ChemMedChem, 2015, v. 10, n. 7, p. 1274, doi. 10.1002/cmdc.201500172

By:

Rex, John H.

Publication type:

Article

A Phytochemical-Halogenated Quinoline Combination Therapy Strategy for the Treatment of Pathogenic Bacteria.

Published in:

ChemMedChem, 2015, v. 10, n. 7, p. 1157, doi. 10.1002/cmdc.201500179

By:

Abouelhassan, Yasmeen;
Garrison, Aaron T.;
Bai, Fang;
Norwood, Verrill M.;
Nguyen, Minh Thu;
Jin, Shouguang;
Huigens, Robert W.

Publication type:

Article

Evaluation of (4-Arylpiperidin-1-yl)cyclopentanecarboxamides As High-Affinity and Long-Residence-Time Antagonists for the CCR2 Receptor.

Published in:

ChemMedChem, 2015, v. 10, n. 7, p. 1249, doi. 10.1002/cmdc.201500058

By:

Vilums, Maris;
Zweemer, Annelien J. M.;
Dilanchian, Arian;
van Veldhoven, Jacobus P. D.;
de Vries, Henk;
Brussee, Johannes;
Saunders, John;
Stamos, Dean;
Heitman, Laura H.;
IJzerman, Adriaan P.

Publication type:

Article

Human-Based Systems for Translational Research. Edited by Robert Coleman.

Published in:

ChemMedChem, 2015, v. 10, n. 7, p. 1273, doi. 10.1002/cmdc.201500120

By:

Ward, Simon E.

Publication type:

Article

Target Fishing by Cross-Docking to Explain Polypharmacological Effects.

Published in:

ChemMedChem, 2015, v. 10, n. 7, p. 1209, doi. 10.1002/cmdc.201500123

By:

Patel, Hitesh;
Lucas, Xavier;
Bendik, Igor;
Günther, Stefan;
Merfort, Irmgard

Publication type:

Article

Tricycloundecane Derivatives as Potential N-Methyl- D-aspartate (NMDA) Receptor and Voltage-Gated Calcium Channel Modulators.

Published in:

ChemMedChem, 2015, v. 10, n. 7, p. 1259, doi. 10.1002/cmdc.201500072

By:

Egunlusi, Ayodeji O.;
Malan, Sarel F.;
Joubert, Jacques

Publication type:

Article

Spotlights on our sister journals: ChemMedChem 7/2015.

Published in:: ChemMedChem, 2015, v. 10, n. 7, p. 1128, doi. 10.1002/cmdc.201580713
Publication type:: Article

Potent, Metabolically Stable 2-Alkyl-8-(2 H-1,2,3-triazol-2-yl)-9 H-adenines as Adenosine A<sub>2A</sub> Receptor Ligands.

Published in:

ChemMedChem, 2015, v. 10, n. 7, p. 1149, doi. 10.1002/cmdc.201500113

By:

Pace, Silvia;
Brogin, Giandomenico;
Stasi, Maria Antonietta;
Riccioni, Teresa;
Borsini, Franco;
Capocasa, Francesca;
Manera, Francesco;
Tallarico, Carlo;
Grossi, Pietro;
Vacondio, Federica;
Bassi, Michele;
Bartoccini, Francesca;
Lucarini, Simone;
Piersanti, Giovanni;
Tarzia, Giorgio;
Cabri, Walter;
Minetti, Patrizia

Publication type:

Article

Metabolic Instability of Cyanothiazolidine-Based Prolyl Oligopeptidase Inhibitors: a Structural Assignment Challenge and Potential Medicinal Chemistry Implications.

Published in:

ChemMedChem, 2015, v. 10, n. 7, p. 1174, doi. 10.1002/cmdc.201500114

By:

Schiavini, Paolo;
Pottel, Joshua;
Moitessier, Nicolas;
Auclair, Karine

Publication type:

Article

Inside Cover: Synthesis, Chiral Separation, Absolute Configuration Assignment, and Biological Activity of Enantiomers of Retro-1 as Potent Inhibitors of Shiga Toxin (ChemMedChem 7/2015).

Published in:

ChemMedChem, 2015, v. 10, n. 7, p. 1118, doi. 10.1002/cmdc.201590020

By:

Abdelkafi, Hajer;
Michau, Aurélien;
Clerget, Alexandra;
Buisson, David‐Alexandre;
Johannes, Ludger;
Gillet, Daniel;
Barbier, Julien;
Cintrat, Jean‐Christophe

Publication type:

Article

Graphical Abstract: ChemMedChem 7/2015.

Published in:: ChemMedChem, 2015, v. 10, n. 7, p. 1119, doi. 10.1002/cmdc.201590021
Publication type:: Article

Back Cover: Metabolic Instability of Cyanothiazolidine-Based Prolyl Oligopeptidase Inhibitors: a Structural Assignment Challenge and Potential Medicinal Chemistry Implications (ChemMedChem 7/2015).

Published in:

ChemMedChem, 2015, v. 10, n. 7, p. 1276, doi. 10.1002/cmdc.201590022

By:

Schiavini, Paolo;
Pottel, Joshua;
Moitessier, Nicolas;
Auclair, Karine

Publication type:

Article

Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases.

Published in:

ChemMedChem, 2015, v. 10, n. 7, p. 1163, doi. 10.1002/cmdc.201500131

By:

von Nussbaum, Franz;
Li, Volkhart M.‐J.;
Allerheiligen, Swen;
Anlauf, Sonja;
Bärfacker, Lars;
Bechem, Martin;
Delbeck, Martina;
Fitzgerald, Mary F.;
Gerisch, Michael;
Gielen‐Haertwig, Heike;
Haning, Helmut;
Karthaus, Dagmar;
Lang, Dieter;
Lustig, Klemens;
Meibom, Daniel;
Mittendorf, Joachim;
Rosentreter, Ulrich;
Schäfer, Martina;
Schäfer, Stefan;
Schamberger, Jens

Publication type:

Article

Comparative Assessment of Complex Stabilities of Radiocopper Chelating Agents by a Combination of Complex Challenge and in vivo Experiments.

Published in:

ChemMedChem, 2015, v. 10, n. 7, p. 1200, doi. 10.1002/cmdc.201500132

By:

Litau, Shanna;
Seibold, Uwe;
Vall‐Sagarra, Alicia;
Fricker, Gert;
Wängler, Björn;
Wängler, Carmen

Publication type:

Article

Medicinal Chemists of the 21<sup>st</sup> Century-Who Are We and Where to Go?

Published in:

2015

By:

Nussbaumer, Peter

Publication type:

Other

Design, Synthesis, and Biological Evaluation of Novel Nonsteroidal Farnesoid X Receptor (FXR) Antagonists: Molecular Basis of FXR Antagonism.

Published in:

ChemMedChem, 2015, v. 10, n. 7, p. 1184, doi. 10.1002/cmdc.201500136

By:

Huang, Huang;
Si, Pei;
Wang, Lei;
Xu, Yong;
Xu, Xin;
Zhu, Jin;
Jiang, Hualiang;
Li, Weihua;
Chen, Lili;
Li, Jian

Publication type:

Article

Biocatalysis at Work: Applications in the Development of Sagopilone.

Published in:

ChemMedChem, 2015, v. 10, n. 7, p. 1240, doi. 10.1002/cmdc.201500138

By:

Gottfried, Kathrin;
Klar, Ulrich;
Platzek, Johannes;
Zorn, Ludwig

Publication type:

Article

Synthesis, Chiral Separation, Absolute Configuration Assignment, and Biological Activity of Enantiomers of Retro-1 as Potent Inhibitors of Shiga Toxin.

Published in:

ChemMedChem, 2015, v. 10, n. 7, p. 1153, doi. 10.1002/cmdc.201500139

By:

Abdelkafi, Hajer;
Michau, Aurélien;
Clerget, Alexandra;
Buisson, David‐Alexandre;
Johannes, Ludger;
Gillet, Daniel;
Barbier, Julien;
Cintrat, Jean‐Christophe

Publication type:

Article

Selective Targeting of the TPX2 Site of Importin-α Using Fragment-Based Ligand Design.

Published in:

ChemMedChem, 2015, v. 10, n. 7, p. 1232, doi. 10.1002/cmdc.201500014

By:

Holvey, Rhian S.;
Valkov, Eugene;
Neal, David;
Stewart, Murray;
Abell, Chris

Publication type:

Article

Frontiers in Medicinal Chemistry 2015: Meet the Experts of MedChem near the Cradle of Medicinal and Pharmaceutical Chemistry.

Published in:

ChemMedChem, 2015, v. 10, n. 7, p. 1267, doi. 10.1002/cmdc.201500208

By:

Wegscheid‐Gerlach, Christof;
Gerber, Hans‐Dieter;
Diederich, Wibke E.

Publication type:

Article

Protein Flexibility in Drug Discovery: From Theory to Computation.

Published in:

ChemMedChem, 2015, v. 10, n. 7, p. 1141, doi. 10.1002/cmdc.201500086

By:

Buonfiglio, Rosa;
Recanatini, Maurizio;
Masetti, Matteo

Publication type:

Article