Works matching IS 18607179 AND DT 2015 AND VI 10 AND IP 2

Results: 24

O-(Triazolyl)methyl Carbamates as a Novel and Potent Class of Fatty Acid Amide Hydrolase (FAAH) Inhibitors.

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 380, doi. 10.1002/cmdc.201402374

By:

Colombano, Giampiero;
Albani, Clara;
Ottonello, Giuliana;
Ribeiro, Alison;
Scarpelli, Rita;
Tarozzo, Glauco;
Daglian, Jennifer;
Jung, Kwang‐Mook;
Piomelli, Daniele;
Bandiera, Tiziano

Publication type:

Article

Generation and Screening of Oxime Libraries Addressing the Neuronal GABA Transporter GAT1.

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 396, doi. 10.1002/cmdc.201402376

By:

Kern, Felix T.;
Wanner, Klaus T.

Publication type:

Article

Oxidation Potentials of N-Modified Derivatives of the Analgesic Flupirtine Linked to Potassium K<sub>V</sub>7 Channel Opening Activity But Not Hepatocyte Toxicity.

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 368, doi. 10.1002/cmdc.201402442

By:

Lemmerhirt, Christian J.;
Rombach, Mirko;
Bodtke, Anja;
Bednarski, Patrick J.;
Link, Andreas

Publication type:

Article

'Squalenoylcurcumin' Nanoassemblies as Water-Dispersible Drug Candidates with Antileishmanial Activity.

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 411, doi. 10.1002/cmdc.201402449

By:

Cheikh‐Ali, Zakaria;
Caron, Joachim;
Cojean, Sandrine;
Bories, Christian;
Couvreur, Patrick;
Loiseau, Philippe M.;
Desmaële, Didier;
Poupon, Erwan;
Champy, Pierre

Publication type:

Article

Discovery of MK-8970: An Acetal Carbonate Prodrug of Raltegravir with Enhanced Colonic Absorption.

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 245, doi. 10.1002/cmdc.201402393

By:

Walji, Abbas M.;
Sanchez, Rosa I.;
Clas, Sophie‐Dorothee;
Nofsinger, Rebecca;
de Lera Ruiz, Manuel;
Li, Jing;
Bennet, Amrithraj;
John, Christopher;
Bennett, David Jonathan;
Sanders, John M.;
Di Marco, Christina N.;
Kim, Somang Hope;
Balsells, Jaume;
Ceglia, Scott S.;
Dang, Qun;
Manser, Kimberly;
Nissley, Becky;
Wai, John S.;
Hafey, Michael;
Wang, Junying

Publication type:

Article

6,7-Dimethoxy-2-{2-[4-(1 H-1,2,3-triazol-1-yl)phenyl]ethyl}-1,2,3,4-tetrahydroisoquinolines as Superior Reversal Agents for P-Glycoprotein-Mediated Multidrug Resistance.

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 336, doi. 10.1002/cmdc.201402463

By:

Liu, Baomin;
Qiu, Qianqian;
Zhao, Tianxiao;
Jiao, Lei;
Li, Yunman;
Huang, Wenlong;
Qian, Hai

Publication type:

Article

Design, Synthesis, and Biological Evaluation of Unconventional Aminopyrimidine, Aminopurine, and Amino-1,3,5-triazine Methyloxynucleosides.

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 321, doi. 10.1002/cmdc.201402465

By:

Fernández‐Cureses, Gloria;
de Castro, Sonia;
Jimeno, María‐Luisa;
Balzarini, Jan;
Camarasa, María‐José

Publication type:

Article

Investigating the Anti-leishmanial Effects of Linear Peptoids.

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 233, doi. 10.1002/cmdc.201402416

By:

Eggimann, Gabriela A.;
Bolt, Hannah L.;
Denny, Paul W.;
Cobb, Steven L.

Publication type:

Article

From Ergolines to Indoles: Improved Inhibitors of the Human H3 Receptor for the Treatment of Narcolepsy.

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 266, doi. 10.1002/cmdc.201402418

By:

Auberson, Yves P.;
Troxler, Thomas;
Zhang, Xuechun;
Yang, Charles R.;
Feuerbach, Dominik;
Liu, Yu‐Chih;
Lagu, Bharat;
Perrone, Mark;
Lei, Lijun;
Shen, Xiaoxia;
Zhang, Dushan;
Wang, Chunxiu;
Wang, Tie‐Lin;
Briner, Karin;
Bock, Mark G.

Publication type:

Article

Electrochemical and mARC-Catalyzed Enzymatic Reduction of para-Substituted Benzamidoximes: Consequences for the Prodrug Concept 'Amidoximes instead of Amidines'.

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 360, doi. 10.1002/cmdc.201402437

By:

Bauch, Eva;
Reichmann, Debora;
Mendel, Ralf‐Rainer;
Bittner, Florian;
Manke, Anne‐Marie;
Kurz, Philipp;
Girreser, Ulrich;
Havemeyer, Antje;
Clement, Bernd

Publication type:

Article

Therapeutic Fc-Fusion Proteins. Edited by Steven M. Chamow, Thomas Ryll, Henry B. Lowman, Deborah Farson.

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 419, doi. 10.1002/cmdc.201402506

By:

Berraondo, Pedro

Publication type:

Article

Cover Picture: Discovery of MK-8970: An Acetal Carbonate Prodrug of Raltegravir with Enhanced Colonic Absorption (ChemMedChem 2/2015).

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 213, doi. 10.1002/cmdc.201590000

By:

Walji, Abbas M.;
Sanchez, Rosa I.;
Clas, Sophie‐Dorothee;
Nofsinger, Rebecca;
de Lera Ruiz, Manuel;
Li, Jing;
Bennet, Amrithraj;
John, Christopher;
Bennett, David Jonathan;
Sanders, John M.;
Di Marco, Christina N.;
Kim, Somang Hope;
Balsells, Jaume;
Ceglia, Scott S.;
Dang, Qun;
Manser, Kimberly;
Nissley, Becky;
Wai, John S.;
Hafey, Michael;
Wang, Junying

Publication type:

Article

Inside Cover: Investigating the Anti-leishmanial Effects of Linear Peptoids (ChemMedChem 2/2015).

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 214, doi. 10.1002/cmdc.201590001

By:

Eggimann, Gabriela A.;
Bolt, Hannah L.;
Denny, Paul W.;
Cobb, Steven L.

Publication type:

Article

Graphical Abstract: ChemMedChem 2/2015.

Published in:: ChemMedChem, 2015, v. 10, n. 2, p. 215, doi. 10.1002/cmdc.201590002
Publication type:: Article

Spotlights on our sister journals: ChemMedChem 2/2015.

Published in:: ChemMedChem, 2015, v. 10, n. 2, p. 224, doi. 10.1002/cmdc.201580213
Publication type:: Article

Promiscuity and the Conformational Rearrangement of Drug-Like Molecules: Insight from the Protein Data Bank.

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 238, doi. 10.1002/cmdc.201402389

By:

He, Michael W.;
Lee, Patrick S.;
Sweeney, Zachary K.

Publication type:

Article

Optimization of 1,2,5-Thiadiazole Carbamates as Potent and Selective ABHD6 Inhibitors.

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 253, doi. 10.1002/cmdc.201402453

By:

Patel, Jayendra Z.;
Nevalainen, Tapio J.;
Savinainen, Juha R.;
Adams, Yahaya;
Laitinen, Tuomo;
Runyon, Robert S.;
Vaara, Miia;
Ahenkorah, Stephen;
Kaczor, Agnieszka A.;
Navia‐Paldanius, Dina;
Gynther, Mikko;
Aaltonen, Niina;
Joharapurkar, Amit A.;
Jain, Mukul R.;
Haka, Abigail S.;
Maxfield, Frederick R.;
Laitinen, Jarmo T.;
Parkkari, Teija

Publication type:

Article

Next-Generation Sequencing: Current Technologies and Applications. Edited by Jianping Xu.

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 419, doi. 10.1002/cmdc.201402456

By:

van der Straaten, Tahar

Publication type:

Article

Discovery of Mono- and Disubstituted 1 H-Pyrazolo[3,4]pyrimidines and 9 H-Purines as Catalytic Inhibitors of Human DNA Topoisomerase IIα.

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 345, doi. 10.1002/cmdc.201402459

By:

Pogorelčnik, Barbara;
Brvar, Matjaž;
Žegura, Bojana;
Filipič, Metka;
Solmajer, Tom;
Perdih, Andrej

Publication type:

Article

The Use of Thermodynamic and Kinetic Data in Drug Discovery: Decisive Insight or Increasing the Puzzlement?

Published in:

2015

By:

Klebe, Gerhard

Publication type:

Other

Synthesis and in vitro Anticancer Activity of Zinc(II) Phthalocyanines Conjugated with Coumarin Derivatives for Dual Photodynamic and Chemotherapy.

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 304, doi. 10.1002/cmdc.201402401

By:

Zhou, Xiao‐Qin;
Meng, Lu‐Bo;
Huang, Qi;
Li, Jun;
Zheng, Ke;
Zhang, Feng‐Ling;
Liu, Jian‐Yong;
Xue, Jin‐Ping

Publication type:

Article

Optimization of Diarylthiazole B-Raf Inhibitors: Identification of a Compound Endowed with High Oral Antitumor Activity, Mitigated hERG Inhibition, and Low Paradoxical Effect.

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 276, doi. 10.1002/cmdc.201402424

By:

Pulici, Maurizio;
Traquandi, Gabriella;
Marchionni, Chiara;
Modugno, Michele;
Lupi, Rosita;
Amboldi, Nadia;
Casale, Elena;
Colombo, Nicoletta;
Corti, Luca;
Fasolini, Marina;
Gasparri, Fabio;
Pastori, Wilma;
Scolaro, Alessandra;
Donati, Daniele;
Felder, Eduard;
Galvani, Arturo;
Isacchi, Antonella;
Pesenti, Enrico;
Ciomei, Marina

Publication type:

Article

Small-Molecule Inhibitors That Target Protein-Protein Interactions in the RAD51 Family of Recombinases.

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 296, doi. 10.1002/cmdc.201402428

By:

Scott, Duncan E.;
Coyne, Anthony G.;
Venkitaraman, Ashok;
Blundell, Tom L.;
Abell, Chris;
Hyvönen, Marko

Publication type:

Article

Molecular-Target-Based Anticancer Photosensitizer: Synthesis and in vitro Photodynamic Activity of Erlotinib-Zinc(II) Phthalocyanine Conjugates.

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 312, doi. 10.1002/cmdc.201402373

By:

Zhang, Feng‐Ling;
Huang, Qi;
Liu, Jian‐Yong;
Huang, Ming‐Dong;
Xue, Jin‐Ping

Publication type:

Article