Works matching IS 18607179 AND DT 2015 AND VI 10 AND IP 12

Results: 16

Design, Synthesis, and Evaluation of Novel Ferroquine and Phenylequine Analogues as Potential Antiplasmodial Agents.

Published in:

ChemMedChem, 2015, v. 10, n. 12, p. 2099, doi. 10.1002/cmdc.201500349

By:

Jacobs, Leon;
de Kock, Carmen;
de Villiers, Katherine A.;
Smith, Peter J.;
Smith, Vincent J.;
van Otterlo, Willem A. L.;
Blackie, Margaret A. L.

Publication type:

Article

Aryl Bis-Sulfonamide Inhibitors of IspF from Arabidopsis thaliana and Plasmodium falciparum.

Published in:

ChemMedChem, 2015, v. 10, n. 12, p. 2090, doi. 10.1002/cmdc.201500382

By:

Thelemann, Jonas;
Illarionov, Boris;
Barylyuk, Konstantin;
Geist, Julie;
Kirchmair, Johannes;
Schneider, Petra;
Anthore, Lucile;
Root, Katharina;
Trapp, Nils;
Bacher, Adelbert;
Witschel, Matthias;
Zenobi, Renato;
Fischer, Markus;
Schneider, Gisbert;
Diederich, François

Publication type:

Article

Synthesis and Evaluation of Hybrid Structures Composed of Two Glucosylceramide Synthase Inhibitors.

Published in:

ChemMedChem, 2015, v. 10, n. 12, p. 2042, doi. 10.1002/cmdc.201500407

By:

van den Berg, Richard J. B. H. N.;
van Rijssel, Erwin R.;
Ferraz, Maria Joao;
Houben, Judith;
Strijland, Anneke;
Donker‐Koopman, Wilma E.;
Wennekes, Tom;
Bonger, Kimberly M.;
Ghisaidoobe, Amar B. T.;
Hoogendoorn, Sascha;
van der Marel, Gijsbert A.;
Codée, Jeroen D. C.;
Overkleeft, Herman S.;
Aerts, Johannes M. F. G.

Publication type:

Article

Structural Determinants of the Selectivity of 3- Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10.

Published in:

ChemMedChem, 2015, v. 10, n. 12, p. 1989, doi. 10.1002/cmdc.201500393

By:

Ruiz, Francesc X.;
Cousido‐Siah, Alexandra;
Porté, Sergio;
Domínguez, Marta;
Crespo, Isidro;
Rechlin, Chris;
Mitschler, André;
de Lera, Ángel R.;
Martín, María Jesús;
de la Fuente, Jesús Ángel;
Klebe, Gerhard;
Parés, Xavier;
Farrés, Jaume;
Podjarny, Alberto

Publication type:

Article

Enantiopure Indolizinoindolones with in vitro Activity against Blood- and Liver-Stage Malaria Parasites.

Published in:

ChemMedChem, 2015, v. 10, n. 12, p. 2080, doi. 10.1002/cmdc.201500429

By:

Pereira, Nuno A. L.;
Monteiro, Ângelo;
Machado, Marta;
Gut, Jiri;
Molins, Elies;
Perry, M. Jesus;
Dourado, Jorge;
Moreira, Rui;
Rosenthal, Philip J.;
Prudêncio, Miguel;
Santos, Maria M. M.

Publication type:

Article

Synthesis and Biological Evaluation of Novel Epothilone B Side Chain Analogues.

Published in:

ChemMedChem, 2015, v. 10, n. 12, p. 1974, doi. 10.1002/cmdc.201500401

By:

Nicolaou, K. C.;
Rhoades, Derek;
Wang, Yanping;
Totokotsopoulos, Sotirios;
Bai, Ruoli;
Hamel, Ernest

Publication type:

Article

3-Amidocoumarins as Potential Multifunctional Agents against Neurodegenerative Diseases.

Published in:

ChemMedChem, 2015, v. 10, n. 12, p. 2071, doi. 10.1002/cmdc.201500408

By:

Matos, Maria João;
Rodríguez‐Enríquez, Fernanda;
Borges, Fernanda;
Santana, Lourdes;
Uriarte, Eugenio;
Estrada, Martín;
Rodríguez‐Franco, María Isabel;
Laguna, Reyes;
Viña, Dolores

Publication type:

Article

Identification of para-Substituted Benzoic Acid Derivatives as Potent Inhibitors of the Protein Phosphatase Slingshot.

Published in:

ChemMedChem, 2015, v. 10, n. 12, p. 1980, doi. 10.1002/cmdc.201500454

By:

Li, Kang‐shuai;
Xiao, Peng;
Zhang, Dao‐lai;
Hou, Xu‐Ben;
Ge, Lin;
Yang, Du‐xiao;
Liu, Hong‐da;
He, Dong‐fang;
Chen, Xu;
Han, Ke‐rui;
Song, Xiao‐yuan;
Yu, Xiao;
Fang, Hao;
Sun, Jin‐peng

Publication type:

Article

Computational Chemistry in the Pharmaceutical Industry: From Childhood to Adolescence.

Published in:

ChemMedChem, 2015, v. 10, n. 12, p. 1958, doi. 10.1002/cmdc.201500346

By:

Hillisch, Alexander;
Heinrich, Nikolaus;
Wild, Hanno

Publication type:

Article

Modular Assembly of Allosteric MEK Inhibitor Structural Elements Unravels Potency and Feedback-Modulation Handles.

Published in:

ChemMedChem, 2015, v. 10, n. 12, p. 2004, doi. 10.1002/cmdc.201500442

By:

Hartung, Ingo V.;
Pühler, Florian;
Neuhaus, Roland;
Scholz, Arne;
Siemeister, Gerhard;
Geisler, Jens;
Hillig, Roman C.;
von Ahsen, Oliver;
Hitchcock, Marion

Publication type:

Article

Synthesis and Pharmacological Properties of Silicon-Containing GPR81 and GPR109A Agonists.

Published in:

ChemMedChem, 2015, v. 10, n. 12, p. 2063, doi. 10.1002/cmdc.201500343

By:

Geyer, Marcel;
Baus, Johannes A.;
Fjellström, Ola;
Wellner, Eric;
Gustafsson, Linda;
Tacke, Reinhold

Publication type:

Article

Identification of Aminoimidazole and Aminothiazole Derivatives as Src Family Kinase Inhibitors.

Published in:

ChemMedChem, 2015, v. 10, n. 12, p. 2027, doi. 10.1002/cmdc.201500428

By:

Francini, Cinzia Maria;
Fallacara, Anna Lucia;
Artusi, Roberto;
Mennuni, Laura;
Calgani, Alessia;
Angelucci, Adriano;
Schenone, Silvia;
Botta, Maurizio

Publication type:

Article

Synthetic and Biological Studies of Sesquiterpene Polygodial: Activity of 9-Epipolygodial against Drug- Resistant Cancer Cells.

Published in:

ChemMedChem, 2015, v. 10, n. 12, p. 2014, doi. 10.1002/cmdc.201500360

By:

Dasari, Ramesh;
De Carvalho, Annelise;
Medellin, Derek C.;
Middleton, Kelsey N.;
Hague, Frédéric;
Volmar, Marie N. M.;
Frolova, Liliya V.;
Rossato, Mateus F.;
De La Chapa, Jorge J.;
Dybdal‐Hargreaves, Nicholas F.;
Pillai, Akshita;
Mathieu, Véronique;
Rogelj, Snezna;
Gonzales, Cara B.;
Calixto, João B.;
Evidente, Antonio;
Gautier, Mathieu;
Munirathinam, Gnanasekar;
Glass, Rainer;
Burth, Patricia

Publication type:

Article

We Need 2C but Not 2B: Developing Serotonin 2C (5-HT<sub>2C</sub>) Receptor Agonists for the Treatment of CNS Disorders.

Published in:

ChemMedChem, 2015, v. 10, n. 12, p. 1963, doi. 10.1002/cmdc.201500437

By:

Cheng, Jianjun;
Kozikowski, Alan P.

Publication type:

Article

Targeted Delivery of Proteasome Inhibitors to Somatostatin-Receptor-Expressing Cancer Cells by Octreotide Conjugation.

Published in:

ChemMedChem, 2015, v. 10, n. 12, p. 1969, doi. 10.1002/cmdc.201500449

By:

Beck, Philipp;
Cui, Haissi;
Hegemann, Julian D.;
Marahiel, Mohammed A.;
Krüger, Achim;
Groll, Michael

Publication type:

Article

SPOTLIGHTS...

Published in:: ChemMedChem, 2015, v. 10, n. 12, p. 1, doi. 10.1002/cmdc.201500449
Publication type:: Article