Works matching IS 18607179 AND DT 2014 AND VI 9 AND IP 8

Results: 34

Graphical Abstract: ChemMedChem 8/2014.

Published in:: ChemMedChem, 2014, v. 9, n. 8, p. 1623, doi. 10.1002/cmdc.201490029
Publication type:: Article

Synthesis, σ Receptor Affinity, and Pharmacological Evaluation of 5-Phenylsulfanyl- and 5-Benzyl-Substituted Tetrahydro-2-benzazepines.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1697, doi. 10.1002/cmdc.201402110

By:

Hasebein, Peer;
Frehland, Bastian;
Schepmann, Dirk;
Wünsch, Bernhard

Publication type:

Article

Data Mining in Drug Discovery. Edited by Remy D. Hoffmann, Arnaud Gohier and Pavel Pospisil.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1907, doi. 10.1002/cmdc.201402194

By:

Overington, John P.

Publication type:

Article

Discovery, Synthesis and Characterization of a Highly Muscarinic Acetylcholine Receptor (mAChR)-Selective M5-Orthosteric Antagonist, VU0488130 (ML381): A Novel Molecular Probe.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1677, doi. 10.1002/cmdc.201402051

By:

Gentry, Patrick R.;
Kokubo, Masaya;
Bridges, Thomas M.;
Cho, Hyekyung P.;
Smith, Emery;
Chase, Peter;
Hodder, Peter S.;
Utley, Thomas J.;
Rajapakse, Anuruddha;
Byers, Frank;
Niswender, Colleen M.;
Morrison, Ryan D.;
Daniels, J. Scott;
Wood, Michael R.;
Conn, P. Jeffrey;
Lindsley, Craig W.

Publication type:

Article

Endothelial Transcriptome in Response to Pharmacological Methyltransferase Inhibition.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1755, doi. 10.1002/cmdc.201402091

By:

Okabe, Jun;
Fernandez, Ana Z.;
Ziemann, Mark;
Keating, Samuel T.;
Balcerczyk, Aneta;
El‐Osta, Assam

Publication type:

Article

Improved Bioactivity of Antimicrobial Peptides by Addition of Amino-Terminal Copper and Nickel (ATCUN) Binding Motifs.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1892, doi. 10.1002/cmdc.201402033

By:

Libardo, M. Daben;
Cervantes, Jorge L.;
Salazar, Juan C.;
Angeles‐Boza, Alfredo M.

Publication type:

Article

The Discovery and Development of the N-Substituted trans-3,4-Dimethyl-4-(3′-hydroxyphenyl)piperidine Class of Pure Opioid Receptor Antagonists.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1638, doi. 10.1002/cmdc.201402142

By:

Carroll, F. Ivy;
Dolle, Roland E.

Publication type:

Article

Ergoline-Derived Inverse Agonists of the Human H3 Receptor for the Treatment of Narcolepsy.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1683, doi. 10.1002/cmdc.201490028

By:

Auberson, Yves P.;
Troxler, Thomas;
Zhang, Xuechun;
Yang, Charles R.;
Fendt, Markus;
Feuerbach, Dominik;
Liu, Yu‐Chih;
Lagu, Bharat;
Lerchner, Andreas;
Perrone, Mark;
Lei, Lijun;
Zhang, Chao;
Wang, Chunxiu;
Wang, Tie‐Lin;
Bock, Mark G.

Publication type:

Article

Handbook of LC-MS Bioanalysis. Edited by Wenkui Li, Jie Zhang and Francis L. S. Tse.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1909, doi. 10.1002/cmdc.201402077

By:

Niessen, Wilfried M. A.

Publication type:

Article

Back Cover: 3-(2-Oxoethylidene)indolin-2-one Derivatives Activate Nrf2 and Inhibit NF-κB: Potential Candidates for Chemoprevention (ChemMedChem 8/2014).

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1912, doi. 10.1002/cmdc.201490031

By:

Nagle, Amrita A.;
Reddy, Shridhivya A.;
Bertrand, Helene;
Tajima, Hisashi;
Dang, Truong‐Minh;
Wong, Siew‐Cheng;
Hayes, John D.;
Wells, Geoffrey;
Chew, Eng‐Hui

Publication type:

Article

Cover Picture: Ergoline-Derived Inverse Agonists of the Human H3 Receptor for the Treatment of Narcolepsy (ChemMedChem 8/2014).

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1621, doi. 10.1002/cmdc.201490028

By:

Auberson, Yves P.;
Troxler, Thomas;
Zhang, Xuechun;
Yang, Charles R.;
Fendt, Markus;
Feuerbach, Dominik;
Liu, Yu‐Chih;
Lagu, Bharat;
Lerchner, Andreas;
Perrone, Mark;
Lei, Lijun;
Zhang, Chao;
Wang, Chunxiu;
Wang, Tie‐Lin;
Bock, Mark G.

Publication type:

Article

Design, Synthesis, and Biological Evaluation of 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 Reverse Transcriptase.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1869, doi. 10.1002/cmdc.201402015

By:

Meleddu, Rita;
Cannas, Valeria;
Distinto, Simona;
Sarais, Giorgia;
Del Vecchio, Claudia;
Esposito, Francesca;
Bianco, Giulia;
Corona, Angela;
Cottiglia, Filippo;
Alcaro, Stefano;
Parolin, Cristina;
Artese, Anna;
Scalise, Daniela;
Fresta, Massimo;
Arridu, Antonella;
Ortuso, Francesco;
Maccioni, Elias;
Tramontano, Enzo

Publication type:

Article

32nd Cyprus-Noordwijkerhout-Camerino Symposium: Trends in Drug Research 2014.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1903, doi. 10.1002/cmdc.201402227

By:

Mavromoustakos, Thomas;
Tsotinis, Andreas

Publication type:

Article

Monoamine Oxidase (MAO) Inhibitory Activity: 3-Phenylcoumarins versus 4-Hydroxy-3-phenylcoumarins.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1672, doi. 10.1002/cmdc.201402010

By:

Delogu, Giovanna L.;
Serra, Silvia;
Quezada, Elias;
Uriarte, Eugenio;
Vilar, Santiago;
Tatonetti, Nicholas P.;
Viña, Dolores

Publication type:

Article

Binding to Large Enzyme Pockets: Small-Molecule Inhibitors of Trypanothione Reductase.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1880, doi. 10.1002/cmdc.201402032

By:

Persch, Elke;
Bryson, Steve;
Todoroff, Nickolay K.;
Eberle, Christian;
Thelemann, Jonas;
Dirdjaja, Natalie;
Kaiser, Marcel;
Weber, Maria;
Derbani, Hassan;
Brun, Reto;
Schneider, Gisbert;
Pai, Emil F.;
Krauth‐Siegel, R. Luise;
Diederich, François

Publication type:

Article

Anticancer Ruthenium(III) Complex KP1019 Interferes with ATP-Dependent Ca2+ Translocation by Sarco-Endoplasmic Reticulum Ca2+-ATPase (SERCA).

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1660, doi. 10.1002/cmdc.201402128

By:

Sadafi, Fabrizio‐Zagros;
Massai, Lara;
Bartolommei, Gianluca;
Moncelli, Maria Rosa;
Messori, Luigi;
Tadini‐Buoninsegni, Francesco

Publication type:

Article

Optimisation of Tetrahydroisoquinoline-Based Chimeric Microtubule Disruptors.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1783, doi. 10.1002/cmdc.201402025

By:

Dohle, Wolfgang;
Leese, Mathew P.;
Jourdan, Fabrice L.;
Chapman, Christopher J.;
Hamel, Ernest;
Ferrandis, Eric;
Potter, Barry V. L.

Publication type:

Article

Caulerpenyne and Related Bis-enol Esters Are Novel-Type Inhibitors of Human 5-Lipoxygenase.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1655, doi. 10.1002/cmdc.201402065

By:

Richter, Phillipp;
Schubert, Gregor;
Schaible, Anja Maria;
Cavas, Levent;
Werz, Oliver;
Pohnert, Georg

Publication type:

Article

Predicted Ligands for the Human Urotensin-II G Protein-Coupled Receptor with Some Experimental Validation.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1732, doi. 10.1002/cmdc.201402087

By:

Kim, Soo‐Kyung;
Goddard, William A.;
Yi, Kyu Yang;
Lee, Byung Ho;
Lim, Chae Jo;
Trzaskowski, Bartosz

Publication type:

Article

Spotlights on our sister journals: ChemMedChem 8/2014.

Published in:: ChemMedChem, 2014, v. 9, n. 8, p. 1634, doi. 10.1002/cmdc.201490030
Publication type:: Article

Mixed-Ligand Mononuclear Copper(II) Complex: Crystal Structure and Anticancer Activity.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1665, doi. 10.1002/cmdc.201402060

By:

Qin, Xiu‐Ying;
Liu, Ya‐Nan;
Yu, Qian‐Qian;
Yang, Li‐Cong;
Liu, Ying;
Zhou, Yan‐Hui;
Liu, Jie

Publication type:

Article

8-Benzyltetrahydropyrazino[2,1- f]purinediones: Water-Soluble Tricyclic Xanthine Derivatives as Multitarget Drugs for Neurodegenerative Diseases.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1704, doi. 10.1002/cmdc.201402082

By:

Brunschweiger, Andreas;
Koch, Pierre;
Schlenk, Miriam;
Pineda, Felipe;
Küppers, Petra;
Hinz, Sonja;
Köse, Meryem;
Ullrich, Stefan;
Hockemeyer, Jörg;
Wiese, Michael;
Heer, Jag;
Müller, Christa E.

Publication type:

Article

A Detailed Study of Antibacterial 3-Acyltetramic Acids and 3-Acylpiperidine-2,4-diones.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1826, doi. 10.1002/cmdc.201402093

By:

Jeong, Yong‐Chul;
Bikadi, Zsolt;
Hazai, Eszter;
Moloney, Mark G.

Publication type:

Article

The Effects of Conformational Constraints in the Polyamine Moiety of Philanthotoxins on AMPAR Inhibition.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1725, doi. 10.1002/cmdc.201402109

By:

Franzyk, Henrik;
Grzeskowiak, John W.;
Tikhonov, Denis B.;
Jaroszewski, Jerzy W.;
Mellor, Ian R.

Publication type:

Article

Gyrase ATPase Domain as an Antitubercular Drug Discovery Platform: Structure-Based Design and Lead Optimization of Nitrothiazolyl Carboxamide Analogues.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1850, doi. 10.1002/cmdc.201402035

By:

Jeankumar, Variam Ullas;
Renuka, Janupally;
Kotagiri, Sonali;
Saxena, Shalini;
Kakan, Shruti Singh;
Sridevi, Jonnalagadda Padma;
Yellanki, Swapna;
Kulkarni, Pushkar;
Yogeeswari, Perumal;
Sriram, Dharmarajan

Publication type:

Article

Development of Novel Selective Peptidomimetics Containing a Boronic Acid Moiety, Targeting the 20S Proteasome as Anticancer Agents.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1801, doi. 10.1002/cmdc.201402075

By:

Scarbaci, Kety;
Troiano, Valeria;
Ettari, Roberta;
Pinto, Andrea;
Micale, Nicola;
Di Giovanni, Carmen;
Cerchia, Carmen;
Schirmeister, Tanja;
Novellino, Ettore;
Lavecchia, Antonio;
Zappalà, Maria;
Grasso, Silvana

Publication type:

Article

Synthesis and Biological Evaluation of Papain-Family Cathepsin L-Like Cysteine Protease Inhibitors Containing a 1,4-Benzodiazepine Scaffold as Antiprotozoal Agents.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1817, doi. 10.1002/cmdc.201402079

By:

Ettari, Roberta;
Pinto, Andrea;
Tamborini, Lucia;
Angelo, Ilenia C.;
Grasso, Silvana;
Zappalà, Maria;
Capodicasa, Natale;
Yzeiraj, Laura;
Gruber, Esther;
Aminake, Makoah N.;
Pradel, Gabriele;
Schirmeister, Tanja;
De Micheli, Carlo;
Conti, Paola

Publication type:

Article

3-(2-Oxoethylidene)indolin-2-one Derivatives Activate Nrf2 and Inhibit NF-κB: Potential Candidates for Chemoprevention.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1763, doi. 10.1002/cmdc.201490031

By:

Nagle, Amrita A.;
Reddy, Shridhivya A.;
Bertrand, Helene;
Tajima, Hisashi;
Dang, Truong‐Minh;
Wong, Siew‐Cheng;
Hayes, John D.;
Wells, Geoffrey;
Chew, Eng‐Hui

Publication type:

Article

Diazepinoporphyrazines Containing Peripheral Styryl Substituents and Their Promising Nanomolar Photodynamic Activity against Oral Cancer Cells in Liposomal Formulations.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1775, doi. 10.1002/cmdc.201402085

By:

Piskorz, Jaroslaw;
Konopka, Krystyna;
Düzgüneş, Nejat;
Gdaniec, Zofia;
Mielcarek, Jadwiga;
Goslinski, Tomasz

Publication type:

Article

Chemoinformatics for Drug Discovery. Edited by Jürgen Bajorath.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1906, doi. 10.1002/cmdc.201402199

By:

Poso, Antti

Publication type:

Article

Phytol Derivatives as Drug Resistance Reversal Agents.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1860, doi. 10.1002/cmdc.201402027

By:

Upadhyay, Harish C.;
Dwivedi, Gaurav R.;
Roy, Sudeep;
Sharma, Ashok;
Darokar, Mahendra P.;
Srivastava, Santosh K.

Publication type:

Article

Development of Cyclobutene- and Cyclobutane-Functionalized Fatty Acids with Inhibitory Activity against Mycobacterium tuberculosis.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1838, doi. 10.1002/cmdc.201402067

By:

Sittiwong, Wantanee;
Zinniel, Denise K.;
Fenton, Robert J.;
Marshall, Darrell D.;
Story, Courtney B.;
Kim, Bohkyung;
Lee, Ji‐Young;
Powers, Robert;
Barletta, Raúl G.;
Dussault, Patrick H.

Publication type:

Article

Glucocerebrosidase Enhancers for Selected Gaucher Disease Genotypes by Modification of α-1- C-Substituted Imino- D-xylitols (DIXs) by Click Chemistry.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1744, doi. 10.1002/cmdc.201402023

By:

Serra‐Vinardell, Jenny;
Díaz, Lucía;
Casas, Josefina;
Grinberg, Daniel;
Vilageliu, Lluïsa;
Michelakakis, Helen;
Mavridou, Irene;
Aerts, Johannes M. F. G.;
Decroocq, Camille;
Compain, Philippe;
Delgado, Antonio

Publication type:

Article

Gold(I) N-Heterocyclic Carbene Complexes with Naphthalimide Ligands as Combined Thioredoxin Reductase Inhibitors and DNA Intercalators.

Published in:

ChemMedChem, 2014, v. 9, n. 8, p. 1794, doi. 10.1002/cmdc.201402049

By:

Meyer, Andreas;
Oehninger, Luciano;
Geldmacher, Yvonne;
Alborzinia, Hamed;
Wölfl, Stefan;
Sheldrick, William S.;
Ott, Ingo

Publication type:

Article

Works matching IS 18607179 AND DT 2014 AND VI 9 AND IP 8

Graphical Abstract: ChemMedChem 8/2014.

Synthesis, σ Receptor Affinity, and Pharmacological Evaluation of 5-Phenylsulfanyl- and 5-Benzyl-Substituted Tetrahydro-2-benzazepines.

Data Mining in Drug Discovery. Edited by Remy D. Hoffmann, Arnaud Gohier and Pavel Pospisil.

Discovery, Synthesis and Characterization of a Highly Muscarinic Acetylcholine Receptor (mAChR)-Selective M<sub>5</sub>-Orthosteric Antagonist, VU0488130 (ML381): A Novel Molecular Probe.

Endothelial Transcriptome in Response to Pharmacological Methyltransferase Inhibition.

Improved Bioactivity of Antimicrobial Peptides by Addition of Amino-Terminal Copper and Nickel (ATCUN) Binding Motifs.

The Discovery and Development of the N-Substituted trans-3,4-Dimethyl-4-(3′-hydroxyphenyl)piperidine Class of Pure Opioid Receptor Antagonists.

Ergoline-Derived Inverse Agonists of the Human H3 Receptor for the Treatment of Narcolepsy.

Handbook of LC-MS Bioanalysis. Edited by Wenkui Li, Jie Zhang and Francis L. S. Tse.

Back Cover: 3-(2-Oxoethylidene)indolin-2-one Derivatives Activate Nrf2 and Inhibit NF-κB: Potential Candidates for Chemoprevention (ChemMedChem 8/2014).

Cover Picture: Ergoline-Derived Inverse Agonists of the Human H3 Receptor for the Treatment of Narcolepsy (ChemMedChem 8/2014).

Design, Synthesis, and Biological Evaluation of 1,3-Diarylpropenones as Dual Inhibitors of HIV-1 Reverse Transcriptase.

32nd Cyprus-Noordwijkerhout-Camerino Symposium: Trends in Drug Research 2014.

Monoamine Oxidase (MAO) Inhibitory Activity: 3-Phenylcoumarins versus 4-Hydroxy-3-phenylcoumarins.

Binding to Large Enzyme Pockets: Small-Molecule Inhibitors of Trypanothione Reductase.

Anticancer Ruthenium(III) Complex KP1019 Interferes with ATP-Dependent Ca<sup>2+</sup> Translocation by Sarco-Endoplasmic Reticulum Ca<sup>2+</sup>-ATPase (SERCA).

Optimisation of Tetrahydroisoquinoline-Based Chimeric Microtubule Disruptors.

Caulerpenyne and Related Bis-enol Esters Are Novel-Type Inhibitors of Human 5-Lipoxygenase.

Predicted Ligands for the Human Urotensin-II G Protein-Coupled Receptor with Some Experimental Validation.

Spotlights on our sister journals: ChemMedChem 8/2014.

Mixed-Ligand Mononuclear Copper(II) Complex: Crystal Structure and Anticancer Activity.

8-Benzyltetrahydropyrazino[2,1- f]purinediones: Water-Soluble Tricyclic Xanthine Derivatives as Multitarget Drugs for Neurodegenerative Diseases.

A Detailed Study of Antibacterial 3-Acyltetramic Acids and 3-Acylpiperidine-2,4-diones.

The Effects of Conformational Constraints in the Polyamine Moiety of Philanthotoxins on AMPAR Inhibition.

Gyrase ATPase Domain as an Antitubercular Drug Discovery Platform: Structure-Based Design and Lead Optimization of Nitrothiazolyl Carboxamide Analogues.

Development of Novel Selective Peptidomimetics Containing a Boronic Acid Moiety, Targeting the 20S Proteasome as Anticancer Agents.

Synthesis and Biological Evaluation of Papain-Family Cathepsin L-Like Cysteine Protease Inhibitors Containing a 1,4-Benzodiazepine Scaffold as Antiprotozoal Agents.

3-(2-Oxoethylidene)indolin-2-one Derivatives Activate Nrf2 and Inhibit NF-κB: Potential Candidates for Chemoprevention.

Diazepinoporphyrazines Containing Peripheral Styryl Substituents and Their Promising Nanomolar Photodynamic Activity against Oral Cancer Cells in Liposomal Formulations.

Chemoinformatics for Drug Discovery. Edited by Jürgen Bajorath.

Phytol Derivatives as Drug Resistance Reversal Agents.

Development of Cyclobutene- and Cyclobutane-Functionalized Fatty Acids with Inhibitory Activity against Mycobacterium tuberculosis.

Glucocerebrosidase Enhancers for Selected Gaucher Disease Genotypes by Modification of α-1- C-Substituted Imino- D-xylitols (DIXs) by Click Chemistry.

Gold(I) N-Heterocyclic Carbene Complexes with Naphthalimide Ligands as Combined Thioredoxin Reductase Inhibitors and DNA Intercalators.