Works matching IS 18607179 AND DT 2014 AND VI 9 AND IP 5

Results: 28

Fluorescence Polarization for the Evaluation of Small-Molecule Inhibitors of PCAF BRD/Tat-AcK50 Association.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 928, doi. 10.1002/cmdc.201300499

By:

Hu, Ping;
Wang, Xinghui;
Zhang, Baiqun;
Zhang, Shuai;
Wang, Qiang;
Wang, Zhiyong

Publication type:

Article

Graphical Abstract: ChemMedChem 5/2014.

Published in:: ChemMedChem, 2014, v. 9, n. 5, p. 871, doi. 10.1002/cmdc.201490017
Publication type:: Article

Unfolding and Conformational Variations of Thrombin-Binding DNA Aptamers: Synthesis, Circular Dichroism and Molecular Dynamics Simulations.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 993, doi. 10.1002/cmdc.201300564

By:

Sun, Lidan;
Jin, Hongwei;
Zhao, Xiaoyang;
Liu, Zhenming;
Guan, Yifu;
Yang, Zhenjun;
Zhang, Liangren;
Zhang, Lihe

Publication type:

Article

Inside Cover: Discovery of 5-(2-(Phenylamino)pyrimidin-4-yl)thiazol-2(3 H)-one Derivatives as Potent Mnk2 Inhibitors: Synthesis, SAR Analysis and Biological Evaluation (ChemMedChem 5/2014).

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 862, doi. 10.1002/cmdc.201490016

By:

Diab, Sarah;
Teo, Theodosia;
Kumarasiri, Malika;
Li, Peng;
Yu, Mingfeng;
Lam, Frankie;
Basnet, Sunita K. C.;
Sykes, Matthew J.;
Albrecht, Hugo;
Milne, Robert;
Wang, Shudong

Publication type:

Article

Computational Insight into p21-Activated Kinase 4 Inhibition: A Combined Ligand- and Structure-Based Approach.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 1012, doi. 10.1002/cmdc.201400016

By:

Li, Rui‐Juan;
Wang, Jian;
Xu, Zhen;
Huang, Wan‐Xu;
Li, Jia;
Jin, Sheng‐Fei;
Zhao, Dong‐Mei;
Cheng, Mao‐Sheng

Publication type:

Article

Facile Identification of Dual FLT3-Aurora A Inhibitors: A Computer-Guided Drug Design Approach.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 953, doi. 10.1002/cmdc.201300571

By:

Chang Hsu, Yung;
Ke, Yi‐Yu;
Shiao, Hui‐Yi;
Lee, Chieh‐Chien;
Lin, Wen‐Hsing;
Chen, Chun‐Hwa;
Yen, Kuei‐Jung;
Hsu, John T.‐A.;
Chang, Chungming;
Hsieh, Hsing‐Pang

Publication type:

Article

High-Throughput Synthesis of Peptide α-Thioesters: A Safety Catch Linker Approach Enabling Parallel Hydrogen Fluoride Cleavage.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 1038, doi. 10.1002/cmdc.201300524

By:

Brust, Andreas;
Schroeder, Christina I.;
Alewood, Paul F.

Publication type:

Article

Corrigendum: Methyl, Ethyl, Propyl, Butyl: Futile But Not for Water, as the Correlation of Structure and Thermodynamic Signature Shows in a Congeneric Series of Thermolysin Inhibitors.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 877, doi. 10.1002/cmdc.201400087

By:

Krimmer, Stefan G.;
Betz, Michael;
Heine, Andreas;
Klebe, Gerhard

Publication type:

Article

Nonlinear Dimensionality Reduction for Visualizing Toxicity Data: Distance-Based Versus Topology-Based Approaches.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 1047, doi. 10.1002/cmdc.201400027

By:

Kireeva, Natalia V.;
Ovchinnikova, Svetlana I.;
Tetko, Igor V.;
Asiri, Abdullah M.;
Balakin , Konstantin V.;
Tsivadze, Aslan Yu.

Publication type:

Article

Design, Synthesis, and Activity Evaluation of GK/PPARγ Dual-Target-Directed Ligands as Hypoglycemic Agents.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 922, doi. 10.1002/cmdc.201400009

By:

Lu, Jianxun;
Lei, Lei;
Huan, Yi;
Li, Yongqiang;
Zhang, Lijing;
Shen, Zhufang;
Hu, Wenxiang;
Feng, Zhiqiang

Publication type:

Article

Location and Conformation of Amyloid β(25-35) Peptide and its Sequence-Shuffled Peptides within Membranes: Implications for Aggregation and Toxicity in PC12 Cells.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 1002, doi. 10.1002/cmdc.201400062

By:

Tsai, Hui‐Hsu Gavin;
Lee, Jian‐Bin;
Shih, Yuan‐Ci;
Wan, Lei;
Shieh, Fa‐Kuen;
Chen, Chin‐Yu

Publication type:

Article

Total Synthesis of Anticoagulant Pentasaccharide Fondaparinux.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 1071, doi. 10.1002/cmdc.201400019

By:

Li, Tiehai;
Ye, Hui;
Cao, Xuefeng;
Wang, Jiajia;
Liu, Yonghui;
Zhou, Lifei;
Liu, Qiang;
Wang, Wenjun;
Shen, Jie;
Zhao, Wei;
Wang, Peng

Publication type:

Article

Bis(pentafluorosulfanyl)phenyl Azide as an Expeditious Tool for Click Chemistry toward Antitumor Pharmaceuticals.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 913, doi. 10.1002/cmdc.201400059

By:

Yang, Yu‐Dong;
Tokunaga, Etsuko;
Akiyama, Hidehiko;
Saito, Norimichi;
Shibata, Norio

Publication type:

Article

Development of a Growth-Hormone-Conjugated Nanodiamond Complex for Cancer Therapy.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 1023, doi. 10.1002/cmdc.201300541

By:

Chu, Hsueh‐Liang;
Chen, Hung‐Wei;
Tseng, Shin‐Hua;
Hsu, Ming‐Hua;
Ho, Li‐Ping;
Chou, Fu‐Hsuan;
Li, MD. PhD. Hsing‐Yuan;
Chang, Yu‐Chuan;
Chen, Pei‐Hsin;
Tsai, Li‐Yun;
Chou, Ching‐Chung;
Chen, Jyh Shin;
Cheng, Tsai‐Mu;
Chang, Chia‐Ching

Publication type:

Article

Discovery of 5-(2-(Phenylamino)pyrimidin-4-yl)thiazol-2(3 H)-one Derivatives as Potent Mnk2 Inhibitors: Synthesis, SAR Analysis and Biological Evaluation.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 962, doi. 10.1002/cmdc.201300552

By:

Diab, Sarah;
Teo, Theodosia;
Kumarasiri, Malika;
Li, Peng;
Yu, Mingfeng;
Lam, Frankie;
Basnet, Sunita K. C.;
Sykes, Matthew J.;
Albrecht, Hugo;
Milne, Robert;
Wang, Shudong

Publication type:

Article

Discovery of 14-3-3 Protein-Protein Interaction Inhibitors that Sensitize Multidrug-Resistant Cancer Cells to Doxorubicin and the Akt Inhibitor GSK690693.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 973, doi. 10.1002/cmdc.201400044

By:

Mori, Mattia;
Vignaroli, Giulia;
Cau, Ylenia;
Dinić, Jelena;
Hill, Richard;
Rossi, Matteo;
Colecchia, David;
Pešić, Milica;
Link, Wolfgang;
Chiariello, Mario;
Ottmann, Christian;
Botta, Maurizio

Publication type:

Article

Delivery of Suramin as an Antiviral Agent through Liposomal Systems.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 933, doi. 10.1002/cmdc.201300563

By:

Mastrangelo, Eloise;
Mazzitelli, Stefania;
Fabbri, Jacopo;
Rohayem, Jacques;
Ruokolainen, Janne;
Nykänen, Antti;
Milani, Mario;
Pezzullo, Margherita;
Nastruzzi, Claudio;
Bolognesi, Martino

Publication type:

Article

Cover Picture: Facile Identification of Dual FLT3-Aurora A Inhibitors: A Computer-Guided Drug Design Approach (ChemMedChem 5/2014).

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 861, doi. 10.1002/cmdc.201490015

By:

Chang Hsu, Yung;
Ke, Yi‐Yu;
Shiao, Hui‐Yi;
Lee, Chieh‐Chien;
Lin, Wen‐Hsing;
Chen, Chun‐Hwa;
Yen, Kuei‐Jung;
Hsu, John T.‐A.;
Chang, Chungming;
Hsieh, Hsing‐Pang

Publication type:

Article

Back Cover: 3-Phenylpropanoic Acid-Based Phosphotyrosine (pTyr) Mimetics: Hit Evolution to a Novel Orally Active Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitor (ChemMedChem 5/2014).

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 1084, doi. 10.1002/cmdc.201490019

By:

Tang, Yan‐Bo;
Liu, Jun‐Zheng;
Zhang, Shu‐En;
Du, Xin;
Nie, Feilin;
Tian, Jin‐Ying;
Ye, Fei;
Huang, Kai;
Hu, Jin‐Ping;
Li, Yan;
Xiao, Zhiyan

Publication type:

Article

Synthesis and Biological Evaluation of 2-Substituted-5-(4-nitrophenylsulfonamido)benzoxazoles as Human GST P1-1 Inhibitors, and Description of the Binding Site Features.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 984, doi. 10.1002/cmdc.201400010

By:

Ertan‐Bolelli, Tuğba;
Musdal, Yaman;
Bolelli, Kayhan;
Yilmaz, Serap;
Aksoy, Yasemin;
Yildiz, Ilkay;
Aki‐Yalcin, Esin;
Yalcin, Ismail

Publication type:

Article

3-Phenylpropanoic Acid-Based Phosphotyrosine (pTyr) Mimetics: Hit Evolution to a Novel Orally Active Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitor.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 918, doi. 10.1002/cmdc.201400007

By:

Tang, Yan‐Bo;
Liu, Jun‐Zheng;
Zhang, Shu‐En;
Du, Xin;
Nie, Feilin;
Tian, Jin‐Ying;
Ye, Fei;
Huang, Kai;
Hu, Jin‐Ping;
Li, Yan;
Xiao, Zhiyan

Publication type:

Article

Synthesis and Anti-HCV Entry Activity Studies of β-Cyclodextrin-Pentacyclic Triterpene Conjugates.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 1060, doi. 10.1002/cmdc.201300545

By:

Xiao, Sulong;
Wang, Qi;
Si, Longlong;
Shi, Yongying;
Wang, Han;
Yu, Fei;
Zhang, Yongmin;
Li, Yingbo;
Zheng, Yongxiang;
Zhang, Chuanling;
Wang, Chunguang;
Zhang, Lihe;
Zhou, Demin

Publication type:

Article

In silico Design, Synthesis, and Screening of Novel Deoxyhypusine Synthase Inhibitors Targeting HIV-1 Replication.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 940, doi. 10.1002/cmdc.201300481

By:

Schroeder, Marcus;
Kolodzik, Adrian;
Pfaff, Katharina;
Priyadarshini, Poornima;
Krepstakies, Marcel;
Hauber, Joachim;
Rarey, Matthias;
Meier, Chris

Publication type:

Article

G-Quadruplex Structures and Their Interaction Diversity with Ligands.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 899, doi. 10.1002/cmdc.201300566

By:

Zhang, Sulin;
Wu, Yanling;
Zhang, Wen

Publication type:

Article

Spotlights on our sister journals: ChemMedChem 5/2014.

Published in:: ChemMedChem, 2014, v. 9, n. 5, p. 880, doi. 10.1002/cmdc.201490018
Publication type:: Article

Editorial: Scientific Excellence on the Island of Formosa.

Published in:

2014

By:

Hwu, Reuben Jih‐Ru

Publication type:

Editorial

Getting to the Source: Selective Drug Targeting of Cancer Stem Cells.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 885, doi. 10.1002/cmdc.201400068

By:

Ismail, Fatima;
Winkler, David A.

Publication type:

Article

Hepatocellular Carcinoma Targeting Agents: Conjugates of Nitroimidazoles with Trimethyl Nordihydroguaiaretic Acid.

Published in:

ChemMedChem, 2014, v. 9, n. 5, p. 1030, doi. 10.1002/cmdc.201300521

By:

Hsu, Ming‐Hua;
Wu, Szu‐Chun;
Pao, Kuan‐Chuan;
Unlu, Irem;
Gnabre, John N.;
Mold, David E.;
Huang, Ru Chih C.;
Hwu, Jih Ru

Publication type:

Article