Works matching IS 18607179 AND DT 2014 AND VI 9 AND IP 3

Results: 30

Design, Synthesis and Biological Evaluation of 4-Amino- N-(4-aminophenyl)benzamide Analogues of Quinoline-Based SGI-1027 as Inhibitors of DNA Methylation.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 590, doi. 10.1002/cmdc.201300420

By:

Rilova, Elodie;
Erdmann, Alexandre;
Gros, Christina;
Masson, Véronique;
Aussagues, Yannick;
Poughon‐Cassabois, Valérie;
Rajavelu, Arumugam;
Jeltsch, Albert;
Menon, Yoann;
Novosad, Natacha;
Gregoire, Jean‐Marc;
Vispé, Stéphane;
Schambel, Philippe;
Ausseil, Fréderic;
Sautel, François;
Arimondo, Paola B.;
Cantagrel, Frédéric

Publication type:

Article

Towards Selective Inhibition of Histone Deacetylase Isoforms: What Has Been Achieved, Where We Are and What Will Be Next.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 523, doi. 10.1002/cmdc.201300413

By:

Thaler, Florian;
Mercurio, Ciro

Publication type:

Article

Discovery of Potent HDAC Inhibitors Based on Chlamydocin with Inhibitory Effects on Cell Migration.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 627, doi. 10.1002/cmdc.201300372

By:

Wang, Shimiao;
Li, Xiaohui;
Wei, Yingdong;
Xiu, Zhilong;
Nishino, Norikazu

Publication type:

Article

Bromodomains and Their Pharmacological Inhibitors.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 438, doi. 10.1002/cmdc.201300434

By:

Gallenkamp, Daniel;
Gelato, Kathy A.;
Haendler, Bernard;
Weinmann, Hilmar

Publication type:

Article

Rational Design of Substrate-Based Multivalent Inhibitors of the Histone Acetyltransferase Tip60.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 537, doi. 10.1002/cmdc.201300478

By:

Yang, Chao;
Ngo, Liza;
Zheng, Y. George

Publication type:

Article

Spotlights on our sister journals: ChemMedChem 3/2014.

Published in:: ChemMedChem, 2014, v. 9, n. 3, p. 430, doi. 10.1002/cmdc.201490008
Publication type:: Article

Structured Water Molecules in the Binding Site of Bromodomains Can Be Displaced by Cosolvent.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 573, doi. 10.1002/cmdc.201300156

By:

Huang, Danzhi;
Rossini, Emanuele;
Steiner, Sandra;
Caflisch, Amedeo

Publication type:

Article

Toward Drug Repurposing in Epigenetics: Olsalazine as a Hypomethylating Compound Active in a Cellular Context.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 560, doi. 10.1002/cmdc.201300555

By:

Méndez‐Lucio, Oscar;
Tran, Jeremy;
Medina‐Franco, José L.;
Meurice, Nathalie;
Muller, Mark

Publication type:

Article

A Cell-Permeable Ester Derivative of the JmjC Histone Demethylase Inhibitor IOX1.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 566, doi. 10.1002/cmdc.201300428

By:

Schiller, Rachel;
Scozzafava, Giuseppe;
Tumber, Anthony;
Wickens, James R.;
Bush, Jacob T.;
Rai, Ganesha;
Lejeune, Clarisse;
Choi, Hwanho;
Yeh, Tzu‐Lan;
Chan, Mun Chiang;
Mott, Bryan T.;
McCullagh, James S. O.;
Maloney, David J.;
Schofield, Christopher J.;
Kawamura, Akane

Publication type:

Article

Lactam-Based HDAC Inhibitors for Anticancer Chemotherapy: Restoration of RUNX3 by Posttranslational Modification and Epigenetic Control.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 649, doi. 10.1002/cmdc.201300393

By:

Cho, Misun;
Choi, Eunhyun;
Kim, Jae Hyun;
Kim, Hwan;
Kim, Hwan Mook;
Lee, Jang Ik;
Hwang, Ki‐Chul;
Kim, Hyun‐Jung;
Han, Gyoonhee

Publication type:

Article

Naphthyridines as Novel BET Family Bromodomain Inhibitors.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 580, doi. 10.1002/cmdc.201300259

By:

Mirguet, Olivier;
Lamotte, Yann;
Chung, Chun‐wa;
Bamborough, Paul;
Delannée, Delphine;
Bouillot, Anne;
Gellibert, Françoise;
Krysa, Gael;
Lewis, Antonia;
Witherington, Jason;
Huet, Pascal;
Dudit, Yann;
Trottet, Lionel;
Nicodeme, Edwige

Publication type:

Article

Graphical Abstract: ChemMedChem 3/2014.

Published in:: ChemMedChem, 2014, v. 9, n. 3, p. 419, doi. 10.1002/cmdc.201490007
Publication type:: Article

Non-radioactive Protein Lysine Methyltransferase Microplate Assay Based on Reading Domains.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 554, doi. 10.1002/cmdc.201300111

By:

Kudithipudi, Srikanth;
Kusevic, Denis;
Jeltsch, Albert

Publication type:

Article

Epigenetic Molecular Recognition: A Biomolecular Modeling Perspective.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 484, doi. 10.1002/cmdc.201300510

By:

Vellore, Nadeem A.;
Baron, Riccardo

Publication type:

Article

Mind the Methyl: Methyllysine Binding Proteins in Epigenetic Regulation.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 466, doi. 10.1002/cmdc.201300422

By:

Wagner, Tobias;
Robaa, Dina;
Sippl, Wolfgang;
Jung, Manfred

Publication type:

Article

Quinoline-Based p300 Histone Acetyltransferase Inhibitors with Pro-apoptotic Activity in Human Leukemia U937 Cells.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 542, doi. 10.1002/cmdc.201300536

By:

Lenoci, Alessia;
Tomassi, Stefano;
Conte, Mariarosaria;
Benedetti, Rosaria;
Rodriguez, Veronica;
Carradori, Simone;
Secci, Daniela;
Castellano, Sabrina;
Sbardella, Gianluca;
Filetici, Patrizia;
Novellino, Ettore;
Altucci, Lucia;
Rotili, Dante;
Mai, Antonello

Publication type:

Article

The Effect of Various Zinc Binding Groups on Inhibition of Histone Deacetylases 1-11.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 614, doi. 10.1002/cmdc.201300433

By:

Madsen, Andreas S.;
Kristensen, Helle M. E.;
Lanz, Gyrithe;
Olsen, Christian A.

Publication type:

Article

Lysine Deacetylase (KDAC) Regulatory Pathways: an Alternative Approach to Selective Modulation.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 511, doi. 10.1002/cmdc.201300444

By:

Van Dyke, Michael W.

Publication type:

Article

The Role of Long Noncoding RNAs in the Epigenetic Control of Gene Expression.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 505, doi. 10.1002/cmdc.201300569

By:

Morlando, Mariangela;
Ballarino, Monica;
Fatica, Alessandro;
Bozzoni, Irene

Publication type:

Article

Inside Cover: A Chemical Tool for In Vitro and In Vivo Precipitation of Lysine Methyltransferase G9a (ChemMedChem 3/2014).

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 414, doi. 10.1002/cmdc.201490006

By:

Konze, Kyle D.;
Pattenden, Samantha G.;
Liu, Feng;
Barsyte‐Lovejoy, Dalia;
Li, Fengling;
Simon, Jeremy M.;
Davis, Ian J.;
Vedadi, Masoud;
Jin, Jian

Publication type:

Article

Histone Deacetylase Inhibitors with Enhanced Enzymatic Inhibition Effects and Potent in vitro and in vivo Antitumor Activities.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 638, doi. 10.1002/cmdc.201300297

By:

Zhang, Lei;
Zhang, Yingjie;
Chou, C. James;
Inks, Elizabeth S.;
Wang, Xuejian;
Li, Xiaoguang;
Hou, Jinning;
Xu, Wenfang

Publication type:

Article

A Chemical Tool for In Vitro and In Vivo Precipitation of Lysine Methyltransferase G9a.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 549, doi. 10.1002/cmdc.201300450

By:

Konze, Kyle D.;
Pattenden, Samantha G.;
Liu, Feng;
Barsyte‐Lovejoy, Dalia;
Li, Fengling;
Simon, Jeremy M.;
Davis, Ian J.;
Vedadi, Masoud;
Jin, Jian

Publication type:

Article

Back Cover: The Effect of Various Zinc Binding Groups on Inhibition of Histone Deacetylases 1-11 (ChemMedChem 3/2014).

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 672, doi. 10.1002/cmdc.201490009

By:

Madsen, Andreas S.;
Kristensen, Helle M. E.;
Lanz, Gyrithe;
Olsen, Christian A.

Publication type:

Article

An Update on Lysine Deacylases Targeting the Expanding 'Acylome'.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 434, doi. 10.1002/cmdc.201300421

By:

Olsen, Christian A.

Publication type:

Article

Synthetic Chromatin Approaches To Probe the Writing and Erasing of Histone Modifications.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 495, doi. 10.1002/cmdc.201300487

By:

Fierz, Beat

Publication type:

Article

A Chimeric SERM-Histone Deacetylase Inhibitor Approach to Breast Cancer Therapy.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 602, doi. 10.1002/cmdc.201300270

By:

Patel, Hitisha K.;
Siklos, Marton I.;
Abdelkarim, Hazem;
Mendonca, Emma L.;
Vaidya, Aditya;
Petukhov, Pavel A.;
Thatcher, Gregory R. J.

Publication type:

Article

Cover Picture: A Chimeric SERM-Histone Deacetylase Inhibitor Approach to Breast Cancer Therapy (ChemMedChem 3/2014).

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 413, doi. 10.1002/cmdc.201490005

By:

Patel, Hitisha K.;
Siklos, Marton I.;
Abdelkarim, Hazem;
Mendonca, Emma L.;
Vaidya, Aditya;
Petukhov, Pavel A.;
Thatcher, Gregory R. J.

Publication type:

Article

Synthesis, Antimalarial Properties, and SAR Studies of Alkoxyurea-Based HDAC Inhibitors.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 665, doi. 10.1002/cmdc.201300469

By:

Hansen, Finn K.;
Skinner‐Adams, Tina S.;
Duffy, Sandra;
Marek, Linda;
Sumanadasa, Subathdrage D. M.;
Kuna, Krystina;
Held, Jana;
Avery, Vicky M.;
Andrews, Katherine T.;
Kurz, Thomas

Publication type:

Article

Design, Synthesis, and Biological Activity of NCC149 Derivatives as Histone Deacetylase 8-Selective Inhibitors.

Published in:

ChemMedChem, 2014, v. 9, n. 3, p. 657, doi. 10.1002/cmdc.201300414

By:

Suzuki, Takayoshi;
Muto, Nobusuke;
Bando, Masashige;
Itoh, Yukihiro;
Masaki, Ayako;
Ri, Masaki;
Ota, Yosuke;
Nakagawa, Hidehiko;
Iida, Shinsuke;
Shirahige, Katsuhiko;
Miyata, Naoki

Publication type:

Article

Targeting Epigenetics in Drug Discovery.

Published in:

2014

By:

Mai, Antonello

Publication type:

Editorial