Works matching IS 18607179 AND DT 2014 AND VI 9 AND IP 2

Results: 21

Design and Synthesis of Tricyclic JAK3 Inhibitors with Picomolar Affinities as Novel Molecular Probes.

Published in:

ChemMedChem, 2014, v. 9, n. 2, p. 277, doi. 10.1002/cmdc.201300520

By:

Gehringer, Matthias;
Pfaffenrot, Ellen;
Bauer, Silke;
Laufer, Stefan A.

Publication type:

Article

Inside Cover: Fluorine NMR-Based Screening on Cell Membrane Extracts (ChemMedChem 2/2014).

Published in:

ChemMedChem, 2014, v. 9, n. 2, p. 242, doi. 10.1002/cmdc.201490001

By:

Veronesi, Marina;
Romeo, Elisa;
Lambruschini, Chiara;
Piomelli, Daniele;
Bandiera, Tiziano;
Scarpelli, Rita;
Garau, Gianpiero;
Dalvit, Claudio

Publication type:

Article

Discovery of 5′′-Chloro- N-[(5,6-dimethoxypyridin-2-yl)methyl]-2,2′:5′,3′′-terpyridine-3′-carboxamide (MK-1064): A Selective Orexin 2 Receptor Antagonist (2-SORA) for the Treatment of Insomnia.

Published in:

ChemMedChem, 2014, v. 9, n. 2, p. 311, doi. 10.1002/cmdc.201300447

By:

Roecker, Anthony J.;
Mercer, Swati P.;
Schreier, John D.;
Cox, Christopher D.;
Fraley, Mark E.;
Steen, Justin T.;
Lemaire, Wei;
Bruno, Joseph G.;
Harrell, C. Meacham;
Garson, Susan L.;
Gotter, Anthony L.;
Fox, Steven V.;
Stevens, Joanne;
Tannenbaum, Pamela L.;
Prueksaritanont, Thomayant;
Cabalu, Tamara D.;
Cui, Donghui;
Stellabott, Joyce;
Hartman, George D.;
Young, Steven D.

Publication type:

Article

A New SiF-Dipropargyl Glycerol Scaffold as a Versatile Prosthetic Group to Design Dimeric Radioligands: Synthesis of the [<sup>18</sup>F]BMPPSiF Tracer to Image Serotonin Receptors.

Published in:

ChemMedChem, 2014, v. 9, n. 2, p. 337, doi. 10.1002/cmdc.201300458

By:

Hazari, Puja Panwar;
Schulz, Jurgen;
Vimont, Delphine;
Chadha, Nidhi;
Allard, Michele;
Szlosek‐Pinaud, Magali;
Fouquet, Eric;
Mishra, Anil Kumar

Publication type:

Article

The Synthesis and Biological Evaluation of Multifunctionalised Derivatives of Noscapine as Cytotoxic Agents.

Published in:

ChemMedChem, 2014, v. 9, n. 2, p. 399, doi. 10.1002/cmdc.201300395

By:

DeBono, Aaron J.;
Mistry, Sarah J.;
Xie, Jinhan;
Muthiah, Divya;
Phillips, Jackson;
Ventura, Sabatino;
Callaghan, Richard;
Pouton, Colin W.;
Capuano, Ben;
Scammells, Peter J.

Publication type:

Article

Toward the Development of Dual-Targeted Glyceraldehyde-3-phosphate Dehydrogenase/Trypanothione Reductase Inhibitors against Trypanosoma brucei and Trypanosoma cruzi.

Published in:

ChemMedChem, 2014, v. 9, n. 2, p. 371, doi. 10.1002/cmdc.201300399

By:

Belluti, Federica;
Uliassi, Elisa;
Veronesi, Giacomo;
Bergamini, Christian;
Kaiser, Marcel;
Brun, Reto;
Viola, Angelo;
Fato, Romana;
Michels, Paul A. M.;
Krauth‐Siegel, R. Luise;
Cavalli, Andrea;
Bolognesi, Maria Laura

Publication type:

Article

Cover Picture: Discovery of 5′′-Chloro- N-[(5,6-dimethoxypyridin-2-yl)methyl]-2,2′:5′,3′′-terpyridine-3′-carboxamide (MK-1064): A Selective Orexin 2 Receptor Antagonist (2-SORA) for the Treatment of Insomnia (ChemMedChem 2/2014)

Published in:

ChemMedChem, 2014, v. 9, n. 2, p. 241, doi. 10.1002/cmdc.201490000

By:

Roecker, Anthony J.;
Mercer, Swati P.;
Schreier, John D.;
Cox, Christopher D.;
Fraley, Mark E.;
Steen, Justin T.;
Lemaire, Wei;
Bruno, Joseph G.;
Harrell, C. Meacham;
Garson, Susan L.;
Gotter, Anthony L.;
Fox, Steven V.;
Stevens, Joanne;
Tannenbaum, Pamela L.;
Prueksaritanont, Thomayant;
Cabalu, Tamara D.;
Cui, Donghui;
Stellabott, Joyce;
Hartman, George D.;
Young, Steven D.

Publication type:

Article

Design, Synthesis and Structure-Activity Relationships Studies on the D Ring of the Natural Product Triptolide.

Published in:

ChemMedChem, 2014, v. 9, n. 2, p. 290, doi. 10.1002/cmdc.201300409

By:

Xu, Hongtao;
Tang, Huanyu;
Feng, Huijin;
Li, Yuanchao

Publication type:

Article

Back Cover: Design and Synthesis of Tricyclic JAK3 Inhibitors with Picomolar Affinities as Novel Molecular Probes (ChemMedChem 2/2014).

Published in:

ChemMedChem, 2014, v. 9, n. 2, p. 412, doi. 10.1002/cmdc.201490004

By:

Gehringer, Matthias;
Pfaffenrot, Ellen;
Bauer, Silke;
Laufer, Stefan A.

Publication type:

Article

Synthesis, Structure-Activity, and Structure-Stability Relationships of 2-Substituted- N-(4-oxo-3-oxetanyl) N-Acylethanolamine Acid Amidase (NAAA) Inhibitors.

Published in:

ChemMedChem, 2014, v. 9, n. 2, p. 323, doi. 10.1002/cmdc.201300416

By:

Vitale, Romina;
Ottonello, Giuliana;
Petracca, Rita;
Bertozzi, Sine Mandrup;
Ponzano, Stefano;
Armirotti, Andrea;
Berteotti, Anna;
Dionisi, Mauro;
Cavalli, Andrea;
Piomelli, Daniele;
Bandiera, Tiziano;
Bertozzi, Fabio

Publication type:

Article

Structure-Based and Fragment-Based GPCR Drug Discovery.

Published in:

ChemMedChem, 2014, v. 9, n. 2, p. 256, doi. 10.1002/cmdc.201300382

By:

Andrews, Stephen P.;
Brown, Giles A.;
Christopher, John A.

Publication type:

Article

Spotlights on our sister journals: ChemMedChem 2/2014.

Published in:: ChemMedChem, 2014, v. 9, n. 2, p. 252, doi. 10.1002/cmdc.201490003
Publication type:: Article

Fluorine NMR-Based Screening on Cell Membrane Extracts.

Published in:

ChemMedChem, 2014, v. 9, n. 2, p. 286, doi. 10.1002/cmdc.201300438

By:

Veronesi, Marina;
Romeo, Elisa;
Lambruschini, Chiara;
Piomelli, Daniele;
Bandiera, Tiziano;
Scarpelli, Rita;
Garau, Gianpiero;
Dalvit, Claudio

Publication type:

Article

Synthesis, Antitubulin, and Antiproliferative SAR of C3/C1-Substituted Tetrahydroisoquinolines.

Published in:

ChemMedChem, 2014, v. 9, n. 2, p. 350, doi. 10.1002/cmdc.201300412

By:

Dohle, Wolfgang;
Leese, Mathew P.;
Jourdan, Fabrice L.;
Major, Meriel R.;
Bai, Ruoli;
Hamel, Ernest;
Ferrandis, Eric;
Kasprzyk, Philip G.;
Fiore, Ann;
Newman, Simon P.;
Purohit, Atul;
Potter, Barry V. L.

Publication type:

Article

Modulation of Biodistribution, Pharmacokinetics, and Photosensitivity with the Delivery Vehicle of a Bacteriochlorin Photosensitizer for Photodynamic Therapy.

Published in:

ChemMedChem, 2014, v. 9, n. 2, p. 390, doi. 10.1002/cmdc.201300449

By:

Saavedra, Raquel;
Rocha, Luis B.;
Dąbrowski, Janusz M.;
Arnaut, Luis G.

Publication type:

Article

Identification of Low-Molecular-Weight Compounds Inhibiting Growth of Corynebacteria: Potential Lead Compounds for Antibiotics.

Published in:

ChemMedChem, 2014, v. 9, n. 2, p. 282, doi. 10.1002/cmdc.201300386

By:

Stark, Jaime L.;
Copeland, Jennifer C.;
Eletsky, Alexander;
Somerville, Greg A.;
Szyperski, Thomas;
Powers, Robert

Publication type:

Article

Covalent Inhibition of the Lymphoid Tyrosine Phosphatase.

Published in:

ChemMedChem, 2014, v. 9, n. 2, p. 296, doi. 10.1002/cmdc.201300404

By:

Ahmed, Vanessa F.;
Bottini, Nunzio;
Barrios, Amy M.

Publication type:

Article

Graphical Abstract: ChemMedChem 2/2014.

Published in:: ChemMedChem, 2014, v. 9, n. 2, p. 243, doi. 10.1002/cmdc.201490002
Publication type:: Article

Development of the First Oral Bioprecursors of Bis-alkylguanidine Antimalarial Drugs.

Published in:

ChemMedChem, 2014, v. 9, n. 2, p. 300, doi. 10.1002/cmdc.201300419

By:

Degardin, Mélissa;
Wein, Sharon;
Duckert, Jean‐Frédéric;
Maynadier, Marjorie;
Guy, Alexandre;
Durand, Thierry;
Escale, Roger;
Vial, Henri;
Vo‐Hoang, Yen

Publication type:

Article

N-Cinnamoylation of Antimalarial Classics: Quinacrine Analogues with Decreased Toxicity and Dual-Stage Activity.

Published in:

ChemMedChem, 2014, v. 9, n. 2, p. 305, doi. 10.1002/cmdc.201300459

By:

Gomes, Ana;
Pérez, Bianca;
Albuquerque, Inês;
Machado, Marta;
Prudêncio, Miguel;
Nogueira, Fátima;
Teixeira, Cátia;
Gomes, Paula

Publication type:

Article

Monovinyl Sulfone β-Cyclodextrin. A Flexible Drug Carrier System.

Published in:

ChemMedChem, 2014, v. 9, n. 2, p. 383, doi. 10.1002/cmdc.201300385

By:

del Castillo, Teresa;
Marales‐Sanfrutos, Julia;
Santoyo‐González, Francisco;
Magez, Stefan;
Lopez‐Jaramillo, F. Javier;
Garcia‐Salcedo, Jose A.

Publication type:

Article