Works matching IS 18607179 AND DT 2014 AND VI 9 AND IP 10

Results: 21

Graphical Abstract: ChemMedChem 10/2014.

Published in:: ChemMedChem, 2014, v. 9, n. 10, p. 2211, doi. 10.1002/cmdc.201490038
Publication type:: Article

Back Cover: Insight into the Interactions between Novel Coumarin Derivatives and Human A3 Adenosine Receptors (ChemMedChem 10/2014).

Published in:

ChemMedChem, 2014, v. 9, n. 10, p. 2392, doi. 10.1002/cmdc.201490039

By:

Matos, Maria João;
Vilar, Santiago;
Kachler, Sonja;
Fonseca, André;
Santana, Lourdes;
Uriarte, Eugenio;
Borges, Fernanda;
Tatonetti, Nicholas P.;
Klotz, Karl‐Norbert

Publication type:

Article

6-Hydroxybenzothiophene Ketones: Potent Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1) Owing to Favorable Molecule Geometry and Conformational Preorganization.

Published in:

ChemMedChem, 2014, v. 9, n. 10, p. 2294, doi. 10.1002/cmdc.201402050

By:

Miralinaghi, Parisa;
Schmitt, Christian;
Hartmann, Rolf W.;
Frotscher, Martin;
Engel, Matthias

Publication type:

Article

Benzocyclobutane, Benzocycloheptane and Heptene Derivatives as Melatonin Agonists and Antagonists.

Published in:

ChemMedChem, 2014, v. 9, n. 10, p. 2238, doi. 10.1002/cmdc.201402122

By:

Tsotinis, Andrew;
Afroudakis, Pandelis A.;
Garratt, Peter J.;
Bocianowska‐Zbrog, Alina;
Sugden, David

Publication type:

Article

Design of a General-Purpose European Compound Screening Library for EU-OPENSCREEN.

Published in:

ChemMedChem, 2014, v. 9, n. 10, p. 2309, doi. 10.1002/cmdc.201402126

By:

Horvath, Dragos;
Lisurek, Michael;
Rupp, Bernd;
Kühne, Ronald;
Specker, Edgar;
von Kries, Jens;
Rognan, Didier;
Andersson, C. David;
Almqvist, Fredrik;
Elofsson, Mikael;
Enqvist, Per‐Anders;
Gustavsson, Anna‐Lena;
Remez, Nikita;
Mestres, Jordi;
Marcou, Gilles;
Varnek, Alexander;
Hibert, Marcel;
Quintana, Jordi;
Frank, Ronald

Publication type:

Article

The Mitochondrial Amidoxime Reducing Component (mARC): Involvement in Metabolic Reduction of N-Oxides, Oximes and N-Hydroxyamidinohydrazones.

Published in:

ChemMedChem, 2014, v. 9, n. 10, p. 2381, doi. 10.1002/cmdc.201402127

By:

Jakobs, Heyka H.;
Froriep, Danilo;
Havemeyer, Antje;
Mendel, Ralf R.;
Bittner, Florian;
Clement, Bernd

Publication type:

Article

The Impact of Cyclopropane Configuration on the Biological Activity of Cyclopropyl-Epothilones.

Published in:

ChemMedChem, 2014, v. 9, n. 10, p. 2227, doi. 10.1002/cmdc.201402129

By:

Gaugaz, Fabienne Z.;
Redondo‐Horcajo, Mariano;
Barasoain, Isabel;
Díaz, J. Fernando;
Cobos‐Correa, Amanda;
Kaufmann, Markus;
Altmann, Karl‐Heinz

Publication type:

Article

Spotlights on our sister journals: ChemMedChem 10/2014.

Published in:: ChemMedChem, 2014, v. 9, n. 10, p. 2218, doi. 10.1002/cmdc.201481013
Publication type:: Article

N-Acyl Derivatives of 4-Phenoxyaniline as Neuroprotective Agents.

Published in:

ChemMedChem, 2014, v. 9, n. 10, p. 2260, doi. 10.1002/cmdc.201402195

By:

Barho, Marlene T.;
Oppermann, Sina;
Schrader, Florian C.;
Degenhardt, Inga;
Elsässer, Katharina;
Wegscheid‐Gerlach, Christof;
Culmsee, Carsten;
Schlitzer, Martin

Publication type:

Article

Combinatorial Multicomponent Access to Natural-Products-Inspired Peptidomimetics: Discovery of Selective Inhibitors of Microbial Metallo-aminopeptidases.

Published in:

ChemMedChem, 2014, v. 9, n. 10, p. 2351, doi. 10.1002/cmdc.201402140

By:

Méndez, Yanira;
Pérez‐Labrada, Karell;
González‐Bacerio, Jorge;
Valdés, Gilberto;
de los Chávez, María Á.;
Osuna, Joel;
Charli, Jean‐Louis;
Pascual, Isel;
Rivera, Daniel G.

Publication type:

Article

4-Benzothiazole-7-hydroxyindolinyl Diaryl Ureas Are Potent P2Y1 Antagonists with Favorable Pharmacokinetics: Low Clearance and Small Volume of Distribution.

Published in:

ChemMedChem, 2014, v. 9, n. 10, p. 2327, doi. 10.1002/cmdc.201402141

By:

Qiao, Jennifer X.;
Wang, Tammy C.;
Hiebert, Sheldon;
Hu, Carol H.;
Schumacher, William A.;
Spronk, Steven A.;
Clark, Charles G.;
Han, Ying;
Hua, Ji;
Price, Laura A.;
Shen, Hong;
Chacko, Silvi A.;
Everlof, Gerry;
Bostwick, Jeffrey S.;
Steinbacher, Thomas E.;
Li, Yi‐Xin;
Huang, Christine S.;
Seiffert, Dietmar A.;
Rehfuss, Robert;
Wexler, Ruth R.

Publication type:

Article

Conjugation to Albumin-Binding Molecule Tags as a Strategy to Improve Both Efficacy and Pharmacokinetic Properties of the Complement Inhibitor Compstatin.

Published in:

ChemMedChem, 2014, v. 9, n. 10, p. 2223, doi. 10.1002/cmdc.201402212

By:

Huang, Yijun;
Reis, Edimara S.;
Knerr, Patrick J.;
van der Donk, Wilfred A.;
Ricklin, Daniel;
Lambris, John D.

Publication type:

Article

Development of Diaminoquinazoline Histone Lysine Methyltransferase Inhibitors as Potent Blood-Stage Antimalarial Compounds.

Published in:

ChemMedChem, 2014, v. 9, n. 10, p. 2360, doi. 10.1002/cmdc.201402098

By:

Sundriyal, Sandeep;
Malmquist, Nicholas A.;
Caron, Joachim;
Blundell, Scott;
Liu, Feng;
Chen, Xin;
Srimongkolpithak, Nitipol;
Jin, Jian;
Charman, Susan A.;
Scherf, Artur;
Fuchter, Matthew J.

Publication type:

Article

Chemical Modification of a Synthetic Small Molecule Boosts Its Biological Efficacy against Pluripotency Genes in Mouse Fibroblasts.

Published in:

ChemMedChem, 2014, v. 9, n. 10, p. 2374, doi. 10.1002/cmdc.201402117

By:

Saha, Abhijit;
Pandian, Ganesh N.;
Sato, Shinsuke;
Taniguchi, Junichi;
Kawamoto, Yusuke;
Hashiya, Kaori;
Bando, Toshikazu;
Sugiyama, Hiroshi

Publication type:

Article

Discovery of Methyl 4′-Methyl-5-(7-nitrobenzo[ c][1,2,5]oxadiazol-4-yl)-[1,1′-biphenyl]-3-carboxylate, an Improved Small-Molecule Inhibitor of c-Myc-Max Dimerization.

Published in:

ChemMedChem, 2014, v. 9, n. 10, p. 2274, doi. 10.1002/cmdc.201402189

By:

Chauhan, Jay;
Wang, Huabo;
Yap, Jeremy L.;
Sabato, Philip E.;
Hu, Angela;
Prochownik, Edward V.;
Fletcher, Steven

Publication type:

Article

Molecular Recognition of Two 2,4- syn-Functionalized ( S)-Glutamate Analogues by the Kainate Receptor GluK3 Ligand Binding Domain.

Published in:

ChemMedChem, 2014, v. 9, n. 10, p. 2254, doi. 10.1002/cmdc.201402204

By:

Venskutonytė, Raminta;
Larsen, Anja P.;
Frydenvang, Karla;
Gajhede, Michael;
Sagot, Emmanuelle;
Assaf, Zeinab;
Gefflaut, Thierry;
Pickering, Darryl S.;
Bunch, Lennart;
Kastrup, Jette S.

Publication type:

Article

Insight into the Interactions between Novel Coumarin Derivatives and Human A3 Adenosine Receptors.

Published in:

ChemMedChem, 2014, v. 9, n. 10, p. 2245, doi. 10.1002/cmdc.201402205

By:

Matos, Maria João;
Vilar, Santiago;
Kachler, Sonja;
Fonseca, André;
Santana, Lourdes;
Uriarte, Eugenio;
Borges, Fernanda;
Tatonetti, Nicholas P.;
Klotz, Karl‐Norbert

Publication type:

Article

Discovery of Natural Products Possessing Selective Eukaryotic Readthrough Activity: 3- epi-Deoxynegamycin and Its Leucine Adduct.

Published in:

ChemMedChem, 2014, v. 9, n. 10, p. 2233, doi. 10.1002/cmdc.201402208

By:

Taguchi, Akihiro;
Hamada, Keisuke;
Kotake, Masaya;
Shiozuka, Masataka;
Nakaminami, Hidemasa;
Pillaiyar, Thanigaimalai;
Takayama, Kentaro;
Yakushiji, Fumika;
Noguchi, Norihisa;
Usui, Takeo;
Matsuda, Ryoichi;
Hayashi, Yoshio

Publication type:

Article

Small Alterations in Cobinamide Structure Considerably Influence sGC Activation.

Published in:

ChemMedChem, 2014, v. 9, n. 10, p. 2344, doi. 10.1002/cmdc.201402209

By:

Giedyk, Maciej;
Proinsias, Keith ó;
Kurcoń, Sylwester;
Sharina, Iraida;
Martin, Emil;
Gryko, Dorota

Publication type:

Article

Structural and Biochemical Studies of Actin in Complex with Synthetic Macrolide Tail Analogues.

Published in:

ChemMedChem, 2014, v. 9, n. 10, p. 2286, doi. 10.1002/cmdc.201402150

By:

Pereira, Jose H.;
Petchprayoon, Chutima;
Hoepker, Alexander C.;
Moriarty, Nigel W.;
Fink, Sarah J.;
Cecere, Giuseppe;
Paterson, Ian;
Adams, Paul D.;
Marriott, Gerard

Publication type:

Article

Cover Picture: Conjugation to Albumin-Binding Molecule Tags as a Strategy to Improve Both Efficacy and Pharmacokinetic Properties of the Complement Inhibitor Compstatin (ChemMedChem 10/2014).

Published in:

ChemMedChem, 2014, v. 9, n. 10, p. 2209, doi. 10.1002/cmdc.201490037

By:

Huang, Yijun;
Reis, Edimara S.;
Knerr, Patrick J.;
van der Donk, Wilfred A.;
Ricklin, Daniel;
Lambris, John D.

Publication type:

Article

Works matching IS 18607179 AND DT 2014 AND VI 9 AND IP 10

Graphical Abstract: ChemMedChem 10/2014.

Back Cover: Insight into the Interactions between Novel Coumarin Derivatives and Human A<sub>3</sub> Adenosine Receptors (ChemMedChem 10/2014).

6-Hydroxybenzothiophene Ketones: Potent Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1) Owing to Favorable Molecule Geometry and Conformational Preorganization.

Benzocyclobutane, Benzocycloheptane and Heptene Derivatives as Melatonin Agonists and Antagonists.

Design of a General-Purpose European Compound Screening Library for EU-OPENSCREEN.

The Mitochondrial Amidoxime Reducing Component (mARC): Involvement in Metabolic Reduction of N-Oxides, Oximes and N-Hydroxyamidinohydrazones.

The Impact of Cyclopropane Configuration on the Biological Activity of Cyclopropyl-Epothilones.

Spotlights on our sister journals: ChemMedChem 10/2014.

N-Acyl Derivatives of 4-Phenoxyaniline as Neuroprotective Agents.

Combinatorial Multicomponent Access to Natural-Products-Inspired Peptidomimetics: Discovery of Selective Inhibitors of Microbial Metallo-aminopeptidases.

4-Benzothiazole-7-hydroxyindolinyl Diaryl Ureas Are Potent P2Y<sub>1</sub> Antagonists with Favorable Pharmacokinetics: Low Clearance and Small Volume of Distribution.

Conjugation to Albumin-Binding Molecule Tags as a Strategy to Improve Both Efficacy and Pharmacokinetic Properties of the Complement Inhibitor Compstatin.

Development of Diaminoquinazoline Histone Lysine Methyltransferase Inhibitors as Potent Blood-Stage Antimalarial Compounds.

Chemical Modification of a Synthetic Small Molecule Boosts Its Biological Efficacy against Pluripotency Genes in Mouse Fibroblasts.

Discovery of Methyl 4′-Methyl-5-(7-nitrobenzo[ c][1,2,5]oxadiazol-4-yl)-[1,1′-biphenyl]-3-carboxylate, an Improved Small-Molecule Inhibitor of c-Myc-Max Dimerization.

Molecular Recognition of Two 2,4- syn-Functionalized ( S)-Glutamate Analogues by the Kainate Receptor GluK3 Ligand Binding Domain.

Insight into the Interactions between Novel Coumarin Derivatives and Human A<sub>3</sub> Adenosine Receptors.

Discovery of Natural Products Possessing Selective Eukaryotic Readthrough Activity: 3- epi-Deoxynegamycin and Its Leucine Adduct.

Small Alterations in Cobinamide Structure Considerably Influence sGC Activation.

Structural and Biochemical Studies of Actin in Complex with Synthetic Macrolide Tail Analogues.

Cover Picture: Conjugation to Albumin-Binding Molecule Tags as a Strategy to Improve Both Efficacy and Pharmacokinetic Properties of the Complement Inhibitor Compstatin (ChemMedChem 10/2014).