Works matching IS 18607179 AND DT 2012 AND VI 7 AND IP 6

Results: 25

Elucidation of Mycobacterium tuberculosis Type II Dehydroquinase Inhibitors using a Fragment Elaboration Strategy.

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 1031, doi. 10.1002/cmdc.201100606

By:

Tran, Anh Thu;
West, Nicholas P.;
Britton, Warwick J.;
Payne, Richard J.

Publication type:

Article

Comparative Molecular Profiling of the PPARα/γ Activator Aleglitazar: PPAR Selectivity, Activity and Interaction with Cofactors.

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 1101, doi. 10.1002/cmdc.201100598

By:

Dietz, Michel;
Mohr, Peter;
Kuhn, Bernd;
Maerki, Hans Peter;
Hartman, Peter;
Ruf, Armin;
Benz, Jörg;
Grether, Uwe;
Wright, Matthew B.

Publication type:

Article

Cover Picture: Hydroxamic Acids as Potent Inhibitors of FeII and MnII E. coli Methionine Aminopeptidase: Biological Activities and X-ray Structures of Oxazole Hydroxamate- EcMetAP-Mn Complexes (ChemMedChem 6/2012).

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 937, doi. 10.1002/cmdc.201290024

By:

Huguet, Florian;
Melet, Armelle;
Alves de Sousa, Rodolphe;
Lieutaud, Aurélie;
Chevalier, Jacqueline;
Maigre, Laure;
Deschamps, Patrick;
Tomas, Alain;
Leulliot, Nicolas;
Pages, Jean-Marie;
Artaud, Isabelle

Publication type:

Article

Back Cover: Discovery of 3 H-Imidazo[4,5- b]pyridines as Potent c-Met Kinase Inhibitors: Design, Synthesis, and Biological Evaluation (ChemMedChem 6/2012).

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 1129, doi. 10.1002/cmdc.201290028

By:

Chen, Danqi;
Wang, Ying;
Ma, Yuchi;
Xiong, Bing;
Ai, Jing;
Chen, Yi;
Geng, Meiyu;
Shen, Jingkang

Publication type:

Article

Docetaxel Nanotechnology in Anticancer Therapy.

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 952, doi. 10.1002/cmdc.201200052

By:

Zhao, Pengxiang;
Astruc, Didier

Publication type:

Article

Preview: ChemMedChem 7/2012.

Published in:: ChemMedChem, 2012, v. 7, n. 6, p. 1127, doi. 10.1002/cmdc.201290023
Publication type:: Article

Spotlights on our sister journals: ChemMedChem 6/2012.

Published in:: ChemMedChem, 2012, v. 7, n. 6, p. 948, doi. 10.1002/cmdc.201290027
Publication type:: Article

Medicinal Chemistry of Nucleic Acids. Edited by Li He Zhang, Zhen Xi and Jyoti Chattopadhyaya.

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 1124, doi. 10.1002/cmdc.201200073

By:

Engels, Joachim W.

Publication type:

Article

Kinase Inhibitor Scaffolds against Neurodegenerative Diseases from a Southern Australian Ascidian, Didemnum sp.

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 983, doi. 10.1002/cmdc.201200169

By:

Plisson, Fabien;
Conte, Melissa;
Khalil, Zeinab;
Huang, Xiao-Cong;
Piggott, Andrew M.;
Capon, Robert J.

Publication type:

Article

Development of Selective Estrogen Receptor Modulator (SERM)-Like Activity Through an Indirect Mechanism of Estrogen Receptor Antagonism: Defining the Binding Mode of 7-Oxabicyclo[2.2.1]hept-5-ene Scaffold Core Ligands.

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 1094, doi. 10.1002/cmdc.201200048

By:

Zheng, Yangfan;
Zhu, Manghong;
Srinivasan, Sathish;
Nwachukwu, Jerome C.;
Cavett, Valerie;
Min, Jian;
Carlson, Kathryn E.;
Wang, Pengcheng;
Dong, Chune;
Katzenellenbogen, John A.;
Nettles, Kendall W.;
Zhou, Hai-Bing

Publication type:

Article

Exploration and Optimization of Structure-Activity Relationships in Drug Design using the Taguchi Method.

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 977, doi. 10.1002/cmdc.201200106

By:

Yeo, Wee Kiang;
Tan, Kheng Lin;
Koh, Siang Boon;
Khan, Matiullah;
Nilar, Shahul;
Go, Mei Lin

Publication type:

Article

Pentacycloundecane-diol-Based HIV-1 Protease Inhibitors: Biological Screening, 2 D NMR, and Molecular Simulation Studies.

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 1009, doi. 10.1002/cmdc.201100512

By:

Honarparvar, Bahareh;
Makatini, Maya M.;
Pawar, Sachin A.;
Petzold, Katja;
Soliman, Mahmoud E. S.;
Arvidsson, Per I.;
Sayed, Yasien;
Govender, Thavendran;
Maguire, Glenn E. M.;
Kruger, Hendrik G.

Publication type:

Article

Graphical Abstract: ChemMedChem 6/2012.

Published in:: ChemMedChem, 2012, v. 7, n. 6, p. 939, doi. 10.1002/cmdc.201290026
Publication type:: Article

Discovery of 3 H-Imidazo[4,5- b]pyridines as Potent c-Met Kinase Inhibitors: Design, Synthesis, and Biological Evaluation.

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 1057, doi. 10.1002/cmdc.201200120

By:

Chen, Danqi;
Wang, Ying;
Ma, Yuchi;
Xiong, Bing;
Ai, Jing;
Chen, Yi;
Geng, Meiyu;
Shen, Jingkang

Publication type:

Article

Structure-Activity Relationships and Mechanism of Action of Eph-ephrin Antagonists: Interaction of Cholanic Acid with the EphA2 Receptor.

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 1071, doi. 10.1002/cmdc.201200102

By:

Tognolini, Massimiliano;
Incerti, Matteo;
Hassan-Mohamed, Iftiin;
Giorgio, Carmine;
Russo, Simonetta;
Bruni, Renato;
Lelli, Barbara;
Bracci, Luisa;
Noberini, Roberta;
Pasquale, Elena B.;
Barocelli, Elisabetta;
Vicini, Paola;
Mor, Marco;
Lodola, Alessio

Publication type:

Article

Synthesis, Anti-HIV Activity Studies, and in silico Rationalization of Cyclobutane-Fused Nucleosides.

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 1044, doi. 10.1002/cmdc.201200059

By:

Figueras, Antoni;
Miralles-Llumà, Rosa;
Flores, Ramon;
Rustullet, Albert;
Busqué, Félix;
Figueredo, Marta;
Font, Josep;
Alibés, Ramon;
Maréchal, Jean-Didier

Publication type:

Article

Therapeutic Oligonucleotides: Methods and Protocols. Edited by John Goodchild.

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 1125, doi. 10.1002/cmdc.201200072

By:

Singh, Yashveer

Publication type:

Article

Synthesis of Gd and 68Ga Complexes in Conjugation with a Conformationally Optimized RGD Sequence as Potential MRI and PET Tumor-Imaging Probes.

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 1084, doi. 10.1002/cmdc.201200043

By:

Manzoni, Leonardo;
Belvisi, Laura;
Arosio, Daniela;
Bartolomeo, Maria Paola;
Bianchi, Aldo;
Brioschi, Chiara;
Buonsanti, Federica;
Cabella, Claudia;
Casagrande, Cesare;
Civera, Monica;
De Matteo, Marilenia;
Fugazza, Lorenza;
Lattuada, Luciano;
Maisano, Federico;
Miragoli, Luigi;
Neira, Cristina;
Pilkington-Miksa, Michael;
Scolastico, Carlo

Publication type:

Article

Hydroxamic Acids as Potent Inhibitors of FeII and MnII E. coli Methionine Aminopeptidase: Biological Activities and X-ray Structures of Oxazole Hydroxamate- EcMetAP-Mn Complexes.

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 1020, doi. 10.1002/cmdc.201200076

By:

Huguet, Florian;
Melet, Armelle;
Alves de Sousa, Rodolphe;
Lieutaud, Aurélie;
Chevalier, Jacqueline;
Maigre, Laure;
Deschamps, Patrick;
Tomas, Alain;
Leulliot, Nicolas;
Pages, Jean-Marie;
Artaud, Isabelle

Publication type:

Article

Molecular Recognition of T:G Mismatched Base Pairs in DNA as Studied by Electrospray Ionization Mass Spectrometry.

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 1112, doi. 10.1002/cmdc.201100526

By:

Riccardi Sirtori, Federico;
Aldini, Giancarlo;
Colombo, Maristella;
Colombo, Nicoletta;
Malyszko, Jan;
Vistoli, Giulio;
D'Alessio, Roberto

Publication type:

Article

Inside Cover: Pentacycloundecane-diol-Based HIV-1 Protease Inhibitors: Biological Screening, 2 D NMR, and Molecular Simulation Studies (ChemMedChem 6/2012).

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 938, doi. 10.1002/cmdc.201290025

By:

Honarparvar, Bahareh;
Makatini, Maya M.;
Pawar, Sachin A.;
Petzold, Katja;
Soliman, Mahmoud E. S.;
Arvidsson, Per I.;
Sayed, Yasien;
Govender, Thavendran;
Maguire, Glenn E. M.;
Kruger, Hendrik G.

Publication type:

Article

Evaluation of Bis-Alkylamidoxime O-Alkylsulfonates as Orally Available Antimalarials.

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 991, doi. 10.1002/cmdc.201200112

By:

Degardin, Mélissa;
Wein, Sharon;
Gouni, Smitha;
Tran Van Ba, Christophe;
Duckert, Jean-Frédéric;
Durand, Thierry;
Escale, Roger;
Vial, Henri;
Vo-Hoang, Yen

Publication type:

Article

Peptide Drug Discovery and Development: Translational Research in Academia and Industry. Edited by Miguel Castanho and Nuno C. Santos.

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 1123, doi. 10.1002/cmdc.201200178

By:

Groner, Bernd

Publication type:

Article

Synthesis, Structure Analysis, and Antitumor Evaluation of 3,6-Dimethyl-1,2,4,5-tetrazine-1,4-dicarboxamide Derivatives.

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 973, doi. 10.1002/cmdc.201200109

By:

Rao, Guo-Wu;
Guo, Yan-Mei;
Hu, Wei-Xiao

Publication type:

Article

The Importance of the trans-Enamine Intermediate as a β-Lactamase Inhibition Strategy Probed in Inhibitor-Resistant SHV β-Lactamase Variants.

Published in:

ChemMedChem, 2012, v. 7, n. 6, p. 1002, doi. 10.1002/cmdc.201200006

By:

Ke, Wei;
Rodkey, Elizabeth A.;
Sampson, Jared M.;
Skalweit, Marion J.;
Sheri, Anjaneyulu;
Pagadala, Sundar Ram Reddy;
Nottingham, Michael D.;
Buynak, John D.;
Bonomo, Robert A.;
van den Akker, Focco

Publication type:

Article

Works matching IS 18607179 AND DT 2012 AND VI 7 AND IP 6

Elucidation of Mycobacterium tuberculosis Type II Dehydroquinase Inhibitors using a Fragment Elaboration Strategy.

Comparative Molecular Profiling of the PPARα/γ Activator Aleglitazar: PPAR Selectivity, Activity and Interaction with Cofactors.

Cover Picture: Hydroxamic Acids as Potent Inhibitors of Fe<sup>II</sup> and Mn<sup>II</sup> E. coli Methionine Aminopeptidase: Biological Activities and X-ray Structures of Oxazole Hydroxamate- EcMetAP-Mn Complexes (ChemMedChem 6/2012).

Back Cover: Discovery of 3 H-Imidazo[4,5- b]pyridines as Potent c-Met Kinase Inhibitors: Design, Synthesis, and Biological Evaluation (ChemMedChem 6/2012).

Docetaxel Nanotechnology in Anticancer Therapy.

Preview: ChemMedChem 7/2012.

Spotlights on our sister journals: ChemMedChem 6/2012.

Medicinal Chemistry of Nucleic Acids. Edited by Li He Zhang, Zhen Xi and Jyoti Chattopadhyaya.

Kinase Inhibitor Scaffolds against Neurodegenerative Diseases from a Southern Australian Ascidian, Didemnum sp.

Development of Selective Estrogen Receptor Modulator (SERM)-Like Activity Through an Indirect Mechanism of Estrogen Receptor Antagonism: Defining the Binding Mode of 7-Oxabicyclo[2.2.1]hept-5-ene Scaffold Core Ligands.

Exploration and Optimization of Structure-Activity Relationships in Drug Design using the Taguchi Method.

Pentacycloundecane-diol-Based HIV-1 Protease Inhibitors: Biological Screening, 2 D NMR, and Molecular Simulation Studies.

Graphical Abstract: ChemMedChem 6/2012.

Discovery of 3 H-Imidazo[4,5- b]pyridines as Potent c-Met Kinase Inhibitors: Design, Synthesis, and Biological Evaluation.

Structure-Activity Relationships and Mechanism of Action of Eph-ephrin Antagonists: Interaction of Cholanic Acid with the EphA2 Receptor.

Synthesis, Anti-HIV Activity Studies, and in silico Rationalization of Cyclobutane-Fused Nucleosides.

Therapeutic Oligonucleotides: Methods and Protocols. Edited by John Goodchild.

Synthesis of Gd and <sup>68</sup>Ga Complexes in Conjugation with a Conformationally Optimized RGD Sequence as Potential MRI and PET Tumor-Imaging Probes.

Hydroxamic Acids as Potent Inhibitors of Fe<sup>II</sup> and Mn<sup>II</sup> E. coli Methionine Aminopeptidase: Biological Activities and X-ray Structures of Oxazole Hydroxamate- EcMetAP-Mn Complexes.

Molecular Recognition of T:G Mismatched Base Pairs in DNA as Studied by Electrospray Ionization Mass Spectrometry.

Inside Cover: Pentacycloundecane-diol-Based HIV-1 Protease Inhibitors: Biological Screening, 2 D NMR, and Molecular Simulation Studies (ChemMedChem 6/2012).

Evaluation of Bis-Alkylamidoxime O-Alkylsulfonates as Orally Available Antimalarials.

Peptide Drug Discovery and Development: Translational Research in Academia and Industry. Edited by Miguel Castanho and Nuno C. Santos.

Synthesis, Structure Analysis, and Antitumor Evaluation of 3,6-Dimethyl-1,2,4,5-tetrazine-1,4-dicarboxamide Derivatives.

The Importance of the trans-Enamine Intermediate as a β-Lactamase Inhibition Strategy Probed in Inhibitor-Resistant SHV β-Lactamase Variants.