Works matching IS 18607179 AND DT 2012 AND VI 7 AND IP 4

Results: 30

HIV-1 Integrase: Mechanism and Inhibitor Design. Edited by Nouri Neamati.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 742, doi. 10.1002/cmdc.201200047

By:

Botta, Maurizio

Publication type:

Article

Diarylheterocycle Core Ring Features Effect in Selective COX-1 Inhibition.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 629, doi. 10.1002/cmdc.201100530

By:

Perrone, Maria Grazia;
Vitale, Paola;
Malerba, Paola;
Altomare, Angela;
Rizzi, Rosanna;
Lavecchia, Antonio;
Di Giovanni, Carmen;
Novellino, Ettore;
Scilimati, Antonio

Publication type:

Article

Pyrazinamide: A Frontline Drug Used for Tuberculosis. Molecular Mechanism of Action Resolved after 50 Years?

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 558, doi. 10.1002/cmdc.201100587

By:

Kalinda, Alvin S.;
Aldrich, Courtney C.

Publication type:

Article

Dual Dehydrosqualene/Squalene Synthase Inhibitors: Leads for Innate Immune System-Based Therapeutics.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 561, doi. 10.1002/cmdc.201100589

By:

Lin, Fu-Yang;
Zhang, Yonghui;
Hensler, Mary;
Liu, Yi-Liang;
Chow, Ohn A.;
Zhu, Wei;
Wang, Ke;
Pang, Ran;
Thienphrapa, Wdee;
Nizet, Victor;
Oldfield, Eric

Publication type:

Article

Spotlights on our sister journals: ChemMedChem 4/2012.

Published in:: ChemMedChem, 2012, v. 7, n. 4, p. 550, doi. 10.1002/cmdc.201290015
Publication type:: Article

G. Klebe.

Published in:: ChemMedChem, 2012, v. 7, n. 4, p. 553, doi. 10.1002/cmdc.201200029
Publication type:: Article

Novel 4-Amino Bis-pyridinium and Bis-quinolinium Derivatives as Choline Kinase Inhibitors with Antiproliferative Activity against the Human Breast Cancer SKBR-3 Cell Line.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 663, doi. 10.1002/cmdc.201100505

By:

Gómez-Pérez, Verónica;
McSorley, Theresa;
See Too, Wei Cun;
Konrad, Manfred;
Campos, Joaquín M.

Publication type:

Article

A 2,6-Disubstituted 4-Anilinoquinazoline Derivative Facilitates Cardiomyogenesis of Embryonic Stem Cells.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 733, doi. 10.1002/cmdc.201100603

By:

Shen, Guofang;
Hu, Ying;
Wu, Jianwei;
Jin, Ke;
Zhu, Danyan;
Zhang, Yandong;
Yu, Yongping;
Lou, Yijia

Publication type:

Article

Dipeptidyl Peptidase IV (DPPIV/CD26)-Based Prodrugs of Hydroxy-Containing Drugs.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 618, doi. 10.1002/cmdc.201100504

By:

Diez-Torrubia, Alberto;
Cabrera, Silvia;
Lambeir, Anne-Marie;
Balzarini, Jan;
Camarasa, María-José;
Velázquez, Sonsoles

Publication type:

Article

Preliminary Study of the Anticancer Applications of Mesoporous Materials Functionalized with the Natural Product Betulinic Acid.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 670, doi. 10.1002/cmdc.201100588

By:

Sánchez-Muñoz, Sergio;
Gómez-Ruiz, Santiago;
Pérez-Quintanilla, Damián;
Morante-Zarcero, Sonia;
Sierra, Isabel;
Prashar, Sanjiv;
Paschke, Reinhard;
Kaluđerović, Goran N.

Publication type:

Article

Synthesis, in vitro Cytotoxicity, and Interaction with DNA of Platinum(II) Complexes with N-Monocycloalkyl Derivatives of 1 R,2 R-Diaminocyclohexane as Carrier Ligands.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 642, doi. 10.1002/cmdc.201100467

By:

Sun, Yanyan;
Gou, Shaohua;
Liu, Fei;
Yin, Runting;
Fang, Lei

Publication type:

Article

Graphical Abstract: ChemMedChem 4/2012.

Published in:: ChemMedChem, 2012, v. 7, n. 4, p. 539, doi. 10.1002/cmdc.201290014
Publication type:: Article

The σ-Hole Phenomenon of Halogen Atoms Forms the Structural Basis of the Strong Inhibitory Potency of C5 Halogen Substituted Glucopyranosyl Nucleosides towards Glycogen Phosphorylase b.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 722, doi. 10.1002/cmdc.201100533

By:

Kantsadi, Anastasia L.;
Hayes, Joseph M.;
Manta, Stella;
Skamnaki, Vicky T.;
Kiritsis, Christos;
Psarra, Anna-Maria G.;
Koutsogiannis, Zissis;
Dimopoulou, Athina;
Theofanous, Stavroula;
Nikoleousakos, Nikolaos;
Zoumpoulakis, Panagiotis;
Kontou, Maria;
Papadopoulos, George;
Zographos, Spyros E.;
Komiotis, Dimitris;
Leonidas, Demetres D.

Publication type:

Article

Spiro[chromane-2,4′-piperidine]-Based Histone Deacetylase Inhibitors with Improved in vivo Activity.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 709, doi. 10.1002/cmdc.201200024

By:

Thaler, Florian;
Varasi, Mario;
Carenzi, Giacomo;
Colombo, Andrea;
Abate, Agnese;
Bigogno, Chiara;
Boggio, Roberto;
Carrara, Simone;
Cataudella, Tiziana;
Dal Zuffo, Roberto;
Reali, Veronica;
Vultaggio, Stefania;
Dondio, Giulio;
Gagliardi, Stefania;
Minucci, Saverio;
Mercurio, Ciro

Publication type:

Article

Tyrosine Kinase Inhibitors Influence ABCG2 Expression in EGFR-Positive MDCK BCRP Cells via the PI3K/Akt Signaling Pathway.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 650, doi. 10.1002/cmdc.201100543

By:

Pick, Anne;
Wiese, Michael

Publication type:

Article

Synthesis and Biological Evaluation of Acridine Derivatives as Antimalarial Agents.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 587, doi. 10.1002/cmdc.201100554

By:

Yu, Xiao-Min;
Ramiandrasoa, Florence;
Guetzoyan, Lucie;
Pradines, Bruno;
Quintino, Edgar;
Gadelle, Daniele;
Forterre, Patrick;
Cresteil, Thierry;
Mahy, Jean-Pierre;
Pethe, Stéphanie

Publication type:

Article

Fluorescein Analogues Inhibit SecA ATPase: The First Sub-micromolar Inhibitor of Bacterial Protein Translocation.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 571, doi. 10.1002/cmdc.201100594

By:

Huang, Ying-Ju;
Wang, Hongyun;
Gao, Fen-Biao;
Li, Minyong;
Yang, Hsiuchin;
Wang, Binghe;
Tai, Phang C.

Publication type:

Article

Synthesis and Evaluation of 1-Amino-6-halo-β-carbolines as Antimalarial and Antiprion Agents.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 578, doi. 10.1002/cmdc.201200002

By:

Thompson, Mark J.;
Louth, Jennifer C.;
Little, Susan M.;
Jackson, Matthew P.;
Boursereau, Yohan;
Chen, Beining;
Coldham, Iain

Publication type:

Article

Discovery of Novel 2- N-Aryl-Substituted Benzenesulfonamidoacetamides: Orally Bioavailable Tubulin Polymerization Inhibitors with Marked Antitumor Activities.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 680, doi. 10.1002/cmdc.201100529

By:

Liu, Zulong;
Zhou, Zuyu;
Tian, Wei;
Fan, Xing;
Xue, Ding;
Yu, Long;
Yu, Qiang;
Long, Ya-Qiu

Publication type:

Article

Inside Cover: Preliminary Study of the Anticancer Applications of Mesoporous Materials Functionalized with the Natural Product Betulinic Acid (ChemMedChem 4/2012).

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 538, doi. 10.1002/cmdc.201290013

By:

Sánchez-Muñoz, Sergio;
Gómez-Ruiz, Santiago;
Pérez-Quintanilla, Damián;
Morante-Zarcero, Sonia;
Sierra, Isabel;
Prashar, Sanjiv;
Paschke, Reinhard;
Kaluđerović, Goran N.

Publication type:

Article

Inside Back Cover: Fluorescein Analogues Inhibit SecA ATPase: The First Sub-micromolar Inhibitor of Bacterial Protein Translocation (ChemMedChem 4/2012).

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 744, doi. 10.1002/cmdc.201290017

By:

Huang, Ying-Ju;
Wang, Hongyun;
Gao, Fen-Biao;
Li, Minyong;
Yang, Hsiuchin;
Wang, Binghe;
Tai, Phang C.

Publication type:

Article

Drug Metabolism and Pharmacokinetics Quick Guide. By Siamak C. Khojasteh, Harvey Wong and Cornelis E. C. A. Hop.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 741, doi. 10.1002/cmdc.201200027

By:

Davis, Andy

Publication type:

Article

Fluorogenic Peptide-Based Substrates for Monitoring Thrombin Activity.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 606, doi. 10.1002/cmdc.201100560

By:

van Berkel, Sander S.;
van der Lee, Bas;
van Delft, Floris L.;
Wagenvoord, Rob;
Hemker, H. Coenraad;
Rutjes, Floris P. J. T.

Publication type:

Article

Design, Synthesis, and Biological Activity of Hydroxamic Tertiary Amines as Histone Deacetylase Inhibitors.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 694, doi. 10.1002/cmdc.201100531

By:

Terracciano, Stefania;
Chini, Maria Giovanna;
Riccio, Raffaele;
Bruno, Ines;
Bifulco, Giuseppe

Publication type:

Article

Cytotoxic Salan-Titanium(IV) Complexes: High Activity Toward a Range of Sensitive and Drug-Resistant Cell Lines, and Mechanistic Insights.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 703, doi. 10.1002/cmdc.201100593

By:

Manna, Cesar M.;
Braitbard, Ori;
Weiss, Esther;
Hochman, Jacob;
Tshuva, Edit Y.

Publication type:

Article

In Silico Identification of an Interferon Inhibitor.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 555, doi. 10.1002/cmdc.201100579

By:

Kaiser, Markus;
Ottmann, Christian

Publication type:

Article

Cover Picture: Fluorogenic Peptide-Based Substrates for Monitoring Thrombin Activity (ChemMedChem 4/2012).

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 537, doi. 10.1002/cmdc.201290012

By:

van Berkel, Sander S.;
van der Lee, Bas;
van Delft, Floris L.;
Wagenvoord, Rob;
Hemker, H. Coenraad;
Rutjes, Floris P. J. T.

Publication type:

Article

Preview: ChemMedChem 5/2012.

Published in:: ChemMedChem, 2012, v. 7, n. 4, p. 743, doi. 10.1002/cmdc.201290016
Publication type:: Article

Corrigendum: A Synthetic C34 Trimer of HIV-1 gp41 Shows Significant Increase in Inhibition Potency.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 546, doi. 10.1002/cmdc.201200114

By:

Nomura, Wataru;
Hashimoto, Chie;
Ohya, Aki;
Miyauchi, Kosuke;
Urano, Emiko;
Tanaka, Tomohiro;
Narumi, Tetsuo;
Nakahara, Toru;
Komano, Jun A.;
Yamamoto, Naoki;
Tamamura, Hirokazu

Publication type:

Article

Truncated Reverse Isoxazolidinyl Nucleosides: A New Class of Allosteric HIV-1 Reverse Transcriptase Inhibitors.

Published in:

ChemMedChem, 2012, v. 7, n. 4, p. 565, doi. 10.1002/cmdc.201200022

By:

Romeo, Roberto;
Giofrè, Salvatore V.;
Macchi, Beatrice;
Balestrieri, Emanuela;
Mastino, Antonio;
Merino, Pedro;
Carnovale, Caterina;
Romeo, Giovanni;
Chiacchio, Ugo

Publication type:

Article