Works matching IS 18607179 AND DT 2011 AND VI 6 AND IP 9

Results: 29

Identification of a Glycogen Synthase Kinase-3β Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1593, doi. 10.1002/cmdc.201100188

By:

Kozikowski, Alan P.;
Gunosewoyo, Hendra;
Guo, Songpo;
Gaisina, Irina N.;
Walter, Richard L.;
Ketcherside, Ariel;
McClung, Colleen A.;
Mesecar, Andrew D.;
Caldarone, Barbara

Publication type:

Article

Preview: ChemMedChem 10/2011.

Published in:: ChemMedChem, 2011, v. 6, n. 9, p. 1751, doi. 10.1002/cmdc.201190041
Publication type:: Article

Structure-Guided Design of a Highly Selective Glycogen Synthase Kinase-3β Inhibitor: a Superior Neuroprotective Pyrazolone Showing Antimania Effects.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1587, doi. 10.1002/cmdc.201100231

By:

Chen, Wenwen;
Gaisina, Irina N.;
Gunosewoyo, Hendra;
Malekiani, Sam A.;
Hanania, Taleen;
Kozikowski, Alan P.

Publication type:

Article

Inside Cover: Light-Activated Release of Nitric Oxide with Fluorescence Reporting in Living Cells (ChemMedChem 9/2011).

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1534, doi. 10.1002/cmdc.201190038

By:

Vittorino, Elisa;
Sciortino, Maria Teresa;
Siracusano, Gabriel;
Sortino, Salvatore

Publication type:

Article

Camptothecin and Thiocamptothecin: the Role of Sulfur in Shifting the Hydrolysis Equilibrium towards the Closed Lactone Form.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1706, doi. 10.1002/cmdc.201100206

By:

Pistolozzi, Marco;
Varchi, Greta;
Degli Esposti, Alessandra;
Guerrini, Andrea;
Sotgiu, Giovanna;
Ballestri, Marco;
Ferroni, Claudia;
Venturini, Alessandro;
Bertucci, Carlo

Publication type:

Article

Synthesis and Structure-Activity Relationships of Constrained Heterocyclic Analogues of Combretastatin A4.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1693, doi. 10.1002/cmdc.201100154

By:

Arthuis, Martin;
Pontikis, Renée;
Chabot, Guy G.;
Seguin, Johanne;
Quentin, Lionel;
Bourg, Stéphane;
Morin-Allory, Luc;
Florent, Jean-Claude

Publication type:

Article

Light-Activated Release of Nitric Oxide with Fluorescence Reporting in Living Cells.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1551, doi. 10.1002/cmdc.201100198

By:

Vittorino, Elisa;
Sciortino, Maria Teresa;
Siracusano, Gabriel;
Sortino, Salvatore

Publication type:

Article

The Inverse Type II β-Turn on D-Trp-Phe, a Pharmacophoric Motif for MOR Agonists.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1640, doi. 10.1002/cmdc.201100169

By:

Gentilucci, Luca;
Tolomelli, Alessandra;
De Marco, Rossella;
Spampinato, Santi;
Bedini, Andrea;
Artali, Roberto

Publication type:

Article

Spotlights on our sister journals: ChemMedChem 9/2011.

Published in:: ChemMedChem, 2011, v. 6, n. 9, p. 1546, doi. 10.1002/cmdc.201190040
Publication type:: Article

Application of the Guanidine-Acylguanidine Bioisosteric Approach to Argininamide-Type NPY Y2 Receptor Antagonists.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1727, doi. 10.1002/cmdc.201100241

By:

Pluym, Nikola;
Brennauer, Albert;
Keller, Max;
Ziemek, Ralf;
Pop, Nathalie;
Bernhardt, Günther;
Buschauer, Armin

Publication type:

Article

Bromophycolide A Targets Heme Crystallization in the Human Malaria Parasite Plasmodium falciparum.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1572, doi. 10.1002/cmdc.201100252

By:

Stout, E. Paige;
Cervantes, Serena;
Prudhomme, Jacques;
France, Stefan;
La Clair, James J.;
Le Roch, Karine;
Kubanek, Julia

Publication type:

Article

Cover Picture: From Activity Cliffs to Target-Specific Scoring Models and Pharmacophore Hypotheses (ChemMedChem 9/2011).

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1533, doi. 10.1002/cmdc.201190037

By:

Seebeck, Birte;
Wagener, Markus;
Rarey, Matthias

Publication type:

Article

Adamantyl Ethanone Pyridyl Derivatives: Potent and Selective Inhibitors of Human 11β-Hydroxysteroid Dehydrogenase Type 1.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1616, doi. 10.1002/cmdc.201100182

By:

Su, Xiangdong;
Pradaux-Caggiano, Fabienne;
Vicker, Nigel;
Thomas, Mark P.;
Halem, Heather;
Culler, Michael D.;
Potter, Barry V. L.

Publication type:

Article

Unexpected Opioid Activity Profiles of Analogues of the Novel Peptide Kappa Opioid Receptor Ligand CJ-15,208.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1739, doi. 10.1002/cmdc.201100113

By:

Aldrich, Jane V.;
Kulkarni, Santosh S.;
Senadheera, Sanjeewa N.;
Ross, Nicolette C.;
Reilley, Kate J.;
Eans, Shainnel O.;
Ganno, Michelle L.;
Murray, Thomas F.;
McLaughlin, Jay P.

Publication type:

Article

Hepatitis C: Antiviral Drug Discovery and Development. Edited by Seng-Lai Tan and Yupeng He.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1748, doi. 10.1002/cmdc.201100238

By:

Beaulieu, Pierre L.

Publication type:

Article

Design, Synthesis, and Biological Evaluation of Ring-Opened Bengamide Analogues.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1555, doi. 10.1002/cmdc.201100164

By:

Tai, Wan-Yi;
Zhang, Run-Tao;
Ma, Yi-Ming;
Gu, Min;
Liu, Gang;
Li, Jia;
Nan, Fa-Jun

Publication type:

Article

Tissue Uptake Study and Photodynamic Therapy of Melanoma-Bearing Mice with a Nontoxic, Effective Chlorin.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1715, doi. 10.1002/cmdc.201100186

By:

Dąbrowski, Janusz M.;
Krzykawska, Martyna;
Arnaut, Luis G.;
Pereira, Mariette M.;
Monteiro, Carlos J. P.;
Simões, Sérgio;
Urbańska, Krystyna;
Stochel, Grażyna

Publication type:

Article

[3H]UR-MK136: A Highly Potent and Selective Radioligand for Neuropeptide Y Y1 Receptors.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1566, doi. 10.1002/cmdc.201100197

By:

Keller, Max;
Bernhardt, Günther;
Buschauer, Armin

Publication type:

Article

Design, Synthesis, and Biological Activity of Urea Derivatives as Anaplastic Lymphoma Kinase Inhibitors.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1680, doi. 10.1002/cmdc.201100168

By:

Boije af Gennäs, Gustav;
Mologni, Luca;
Ahmed, Shaheen;
Rajaratnam, Mohanathas;
Marin, Oriano;
Lindholm, Niko;
Viltadi, Michela;
Gambacorti-Passerini, Carlo;
Scapozza, Leonardo;
Yli-Kauhaluoma, Jari

Publication type:

Article

From Activity Cliffs to Target-Specific Scoring Models and Pharmacophore Hypotheses.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1630, doi. 10.1002/cmdc.201100179

By:

Seebeck, Birte;
Wagener, Markus;
Rarey, Matthias

Publication type:

Article

The Evolution of Drug Discovery: From Traditional Medicines to Modern Drugs. By Enrique Raviña.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1746, doi. 10.1002/cmdc.201100321

By:

Steinhagen, Henning

Publication type:

Article

Small Molecule Binding to Proteins: Affinity and Binding/Unbinding Dynamics from Atomistic Simulations.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1578, doi. 10.1002/cmdc.201100237

By:

Huang, Danzhi;
Caflisch, Amedeo

Publication type:

Article

Acetamide Scanning around Bicyclic Thiazoles: SAR at the H3 Receptor.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1559, doi. 10.1002/cmdc.201100248

By:

Denonne, Frédéric;
Célanire, Sylvain;
Christophe, Bernard;
Defays, Sabine;
Delaunoy, Christel;
Delporte, Marie-Laure;
Detrait, Eric;
Durieu, Véronique;
Gillard, Michel;
Lamberty, Yves;
Lorent, Geneviève;
Nicolas, Jean-Marie;
Vanbellinghen, Alain;
Van Houtvin, Nathalie;
Provins, Laurent

Publication type:

Article

An Amphiphilic Conjugate Approach toward the Design and Synthesis of Betulinic Acid-Polyphenol Conjugates as Inhibitors of the HIV-1 gp41 Fusion Core Formation.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1654, doi. 10.1002/cmdc.201100149

By:

Liu, Yan;
Ke, Zhuofeng;
Wu, Kwok Yiu;
Liu, Shuwen;
Chen, Wen-Hua;
Jiang, Shibo;
Jiang, Zhi-Hong

Publication type:

Article

Development of Antitrypanosomal and Antiplasmodial Nonpeptidic Cysteine Protease Inhibitors based on N-Protected-Guanidino-Furan and -Pyrrole Building Blocks.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1581, doi. 10.1002/cmdc.201100189

By:

Langolf, Sebastian;
Machon, Uwe;
Ehlers, Martin;
Sicking, Wilhelm;
Schirmeister, Tanja;
Büchhold, Christian;
Gelhaus, Christoph;
Rosenthal, Philip J.;
Schmuck, Carsten

Publication type:

Article

New Frontiers in Chemical Biology: Enabling Drug Discovery. Edited by Mark E. Bunnage.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1747, doi. 10.1002/cmdc.201100254

By:

Kritzer, Joshua

Publication type:

Article

Graphical Abstract: ChemMedChem 9/2011.

Published in:: ChemMedChem, 2011, v. 6, n. 9, p. 1535, doi. 10.1002/cmdc.201190039
Publication type:: Article

Synthesis of Aryl-Substituted Naphthalene-Linked Pyrrolobenzodiazepine Conjugates as Potential Anticancer Agents with Apoptosis-Inducing Ability.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1665, doi. 10.1002/cmdc.201100207

By:

Kamal, Ahmed;
Reddy, M. Kashi;
Ramaiah, M. Janaki;
Srikanth, Y. V. V.;
Rajender;
Reddy, V. Santosh;
Kumar, G. Bharath;
Pushpavalli, S. N. C. V. L.;
Bag, Indira;
Juvekar, Aarti;
Sen, Subrata;
Zingde, Surekha M.;
Pal-Bhadra, Manika

Publication type:

Article

A Partial Convergence in Action of Methylene Blue and Artemisinins: Antagonism with Chloroquine, a Reversal with Verapamil, and an Insight into the Antimalarial Activity of Chloroquine.

Published in:

ChemMedChem, 2011, v. 6, n. 9, p. 1603, doi. 10.1002/cmdc.201100184

By:

Haynes, Richard K.;
Cheu, Kwan-Wing;
Li, Ka-Yan;
Tang, Maggie Mei-Ki;
Wong, Ho-Ning;
Chen, Min-Jiao;
Guo, Zu-Feng;
Guo, Zhi-Hong;
Coghi, Paolo;
Monti, Diego

Publication type:

Article

Works matching IS 18607179 AND DT 2011 AND VI 6 AND IP 9

Identification of a Glycogen Synthase Kinase-3β Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice.

Preview: ChemMedChem 10/2011.

Structure-Guided Design of a Highly Selective Glycogen Synthase Kinase-3β Inhibitor: a Superior Neuroprotective Pyrazolone Showing Antimania Effects.

Inside Cover: Light-Activated Release of Nitric Oxide with Fluorescence Reporting in Living Cells (ChemMedChem 9/2011).

Camptothecin and Thiocamptothecin: the Role of Sulfur in Shifting the Hydrolysis Equilibrium towards the Closed Lactone Form.

Synthesis and Structure-Activity Relationships of Constrained Heterocyclic Analogues of Combretastatin A4.

Light-Activated Release of Nitric Oxide with Fluorescence Reporting in Living Cells.

The Inverse Type II β-Turn on D-Trp-Phe, a Pharmacophoric Motif for MOR Agonists.

Spotlights on our sister journals: ChemMedChem 9/2011.

Application of the Guanidine-Acylguanidine Bioisosteric Approach to Argininamide-Type NPY Y<sub>2</sub> Receptor Antagonists.

Bromophycolide A Targets Heme Crystallization in the Human Malaria Parasite Plasmodium falciparum.

Cover Picture: From Activity Cliffs to Target-Specific Scoring Models and Pharmacophore Hypotheses (ChemMedChem 9/2011).

Adamantyl Ethanone Pyridyl Derivatives: Potent and Selective Inhibitors of Human 11β-Hydroxysteroid Dehydrogenase Type 1.

Unexpected Opioid Activity Profiles of Analogues of the Novel Peptide Kappa Opioid Receptor Ligand CJ-15,208.

Hepatitis C: Antiviral Drug Discovery and Development. Edited by Seng-Lai Tan and Yupeng He.

Design, Synthesis, and Biological Evaluation of Ring-Opened Bengamide Analogues.

Tissue Uptake Study and Photodynamic Therapy of Melanoma-Bearing Mice with a Nontoxic, Effective Chlorin.

[<sup>3</sup>H]UR-MK136: A Highly Potent and Selective Radioligand for Neuropeptide Y Y<sub>1</sub> Receptors.

Design, Synthesis, and Biological Activity of Urea Derivatives as Anaplastic Lymphoma Kinase Inhibitors.

From Activity Cliffs to Target-Specific Scoring Models and Pharmacophore Hypotheses.

The Evolution of Drug Discovery: From Traditional Medicines to Modern Drugs. By Enrique Raviña.

Small Molecule Binding to Proteins: Affinity and Binding/Unbinding Dynamics from Atomistic Simulations.

Acetamide Scanning around Bicyclic Thiazoles: SAR at the H<sub>3</sub> Receptor.

An Amphiphilic Conjugate Approach toward the Design and Synthesis of Betulinic Acid-Polyphenol Conjugates as Inhibitors of the HIV-1 gp41 Fusion Core Formation.

Development of Antitrypanosomal and Antiplasmodial Nonpeptidic Cysteine Protease Inhibitors based on N-Protected-Guanidino-Furan and -Pyrrole Building Blocks.

New Frontiers in Chemical Biology: Enabling Drug Discovery. Edited by Mark E. Bunnage.

Graphical Abstract: ChemMedChem 9/2011.

Synthesis of Aryl-Substituted Naphthalene-Linked Pyrrolobenzodiazepine Conjugates as Potential Anticancer Agents with Apoptosis-Inducing Ability.

A Partial Convergence in Action of Methylene Blue and Artemisinins: Antagonism with Chloroquine, a Reversal with Verapamil, and an Insight into the Antimalarial Activity of Chloroquine.