Works matching IS 18607179 AND DT 2011 AND VI 6 AND IP 2

Results: 25

Design, Synthesis and Biological Evaluation of Novel Inhibitors of Trypanosoma brucei Pteridine Reductase 1.

Published in:

ChemMedChem, 2011, v. 6, n. 2, p. 302, doi. 10.1002/cmdc.201000450

By:

Spinks, Daniel;
Ong, Han B.;
Mpamhanga, Chidochangu P.;
Shanks, Emma J.;
Robinson, David A.;
Collie, Iain T.;
Read, Kevin D.;
Frearson, Julie A.;
Wyatt, Paul G.;
Brenk, Ruth;
Fairlamb, Alan H.;
Gilbert, Ian H.

Publication type:

Article

Pyrido[1,2- a]benzimidazole-Based Agents Active Against Tuberculosis (TB), Multidrug-Resistant (MDR) TB and Extensively Drug-Resistant (XDR) TB.

Published in:

ChemMedChem, 2011, v. 6, n. 2, p. 334, doi. 10.1002/cmdc.201000490

By:

Pieroni, Marco;
Tipparaju, Suresh K.;
Lun, Shichun;
Song, Yang;
Sturm, A. Willem;
Bishai, William R.;
Kozikowski, Alan P.

Publication type:

Article

Allosteric Inhibitor Development Targeting HIV-1 Integrase.

Published in:

ChemMedChem, 2011, v. 6, n. 2, p. 228, doi. 10.1002/cmdc.201000443

By:

Al-Mawsawi, Laith Q.;
Neamati, Nouri

Publication type:

Article

Fragment-Based Design of Ligands Targeting a Novel Site on the Integrase Enzyme of Human Immunodeficiency Virus 1.

Published in:

ChemMedChem, 2011, v. 6, n. 2, p. 258, doi. 10.1002/cmdc.201000483

By:

Wielens, Jerome;
Headey, Stephen J.;
Deadman, John J.;
Rhodes, David I.;
Parker, Michael W.;
Chalmers, David K.;
Scanlon, Martin J.

Publication type:

Article

Inside Cover: Combating Cystic Fibrosis: In Search for CF Transmembrane Conductance Regulator (CFTR) Modulators / Second-Generation Iminoxylitol-Based Pharmacological Chaperones for the Treatment of Gaucher Disease (ChemMedChem 2/2011).

Published in:

ChemMedChem, 2011, v. 6, n. 2, p. 210, doi. 10.1002/cmdc.201190001

By:

Noy, Efrat;
Senderowitz, Hanoch;
Oulaïdi, Farah;
Front-Deschamps, Sophie;
Gallienne, Estelle;
Lesellier, Eric;
Ikeda, Kyoko;
Asano, Naoki;
Compain, Philippe;
Martin, Olivier R.

Publication type:

Article

Second-Generation Iminoxylitol-Based Pharmacological Chaperones for the Treatment of Gaucher Disease.

Published in:

ChemMedChem, 2011, v. 6, n. 2, p. 353, doi. 10.1002/cmdc.201000469

By:

Oulaïdi, Farah;
Front-Deschamps, Sophie;
Gallienne, Estelle;
Lesellier, Eric;
Ikeda, Kyoko;
Asano, Naoki;
Compain, Philippe;
Martin, Olivier R.

Publication type:

Article

Strategies towards Improving the Pharmacokinetic Profile of ε-Substituted Lysinol-Derived HIV Protease Inhibitors.

Published in:

ChemMedChem, 2011, v. 6, n. 2, p. 253, doi. 10.1002/cmdc.201000395

By:

Rajapakse, Hemaka A.;
Walji, Abbas M.;
Moore, Keith P.;
Zhu, Hong;
Mitra, Aurpon W.;
Gregro, Alison R.;
Tinney, Elizabeth;
Burlein, Christine;
Touch, Sinoeun;
Paton, Brenda L.;
Carroll, Steven S.;
DiStefano, Daniel J.;
Lai, Ming-Tain;
Grobler, Jay A.;
Sanchez, Rosa I.;
Williams, Theresa M.;
Vacca, Joseph P.;
Nantermet, Philippe G.

Publication type:

Article

Synthesis and Evaluation of Potent Ene-yne Inhibitors of Type II Dehydroquinases as Tuberculosis Drug Leads.

Published in:

ChemMedChem, 2011, v. 6, n. 2, p. 262, doi. 10.1002/cmdc.201000399

By:

Tran, Anh Thu;
Cergol, Katie M.;
West, Nicholas P.;
Randall, Elizabeth J.;
Britton, Warwick J.;
Bokhari, Syed Ali Imran;
Ibrahim, Musadiq;
Lapthorn, Adrian J.;
Payne, Richard J.

Publication type:

Article

Improved Inhibitors of Trypanothione Reductase by Combination of Motifs: Synthesis, Inhibitory Potency, Binding Mode, and Antiprotozoal Activities.

Published in:

ChemMedChem, 2011, v. 6, n. 2, p. 292, doi. 10.1002/cmdc.201000420

By:

Eberle, Christian;
Lauber, Birgit Sophia;
Fankhauser, Daniel;
Kaiser, Marcel;
Brun, Reto;
Krauth-Siegel, R. Luise;
Diederich, François

Publication type:

Article

Synthesis and Evaluation of Indatraline-Based Inhibitors for Trypanothione Reductase.

Published in:

ChemMedChem, 2011, v. 6, n. 2, p. 321, doi. 10.1002/cmdc.201000442

By:

Walton, Jeffrey G. A.;
Jones, Deuan C.;
Kiuru, Paula;
Durie, Alastair J.;
Westwood, Nicholas J.;
Fairlamb, Alan H.

Publication type:

Article

GPCR Molecular Pharmacology and Drug Targeting. Edited by Annette Gilchrist.

Published in:

ChemMedChem, 2011, v. 6, n. 2, p. 378, doi. 10.1002/cmdc.201000453

By:

Bojarski, Andrzej J.

Publication type:

Article

Cover Picture: Synthesis and Evaluation of Indatraline-Based Inhibitors for Trypanothione Reductase / Design, Synthesis and Biological Evaluation of Novel Inhibitors of Trypanosoma brucei Pteridine Reductase 1 / Modified 5′-Trityl Nucleosides as Inhibitors of Plasmodium falciparum dUTPase (ChemMedChem 2/2011)

Published in:

ChemMedChem, 2011, v. 6, n. 2, p. 209, doi. 10.1002/cmdc.201190000

By:

Walton, Jeffrey G. A.;
Jones, Deuan C.;
Kiuru, Paula;
Durie, Alastair J.;
Westwood, Nicholas J.;
Fairlamb, Alan H.;
Spinks, Daniel;
Ong, Han B.;
Mpamhanga, Chidochangu P.;
Shanks, Emma J.;
Robinson, David A.;
Collie, Iain T.;
Read, Kevin D.;
Frearson, Julie A.;
Wyatt, Paul G.;
Brenk, Ruth;
Gilbert, Ian H.;
Ruda, Gian Filippo;
Nguyen, Corinne;
Ziemkowski, Przemysław

Publication type:

Article

Synthesis and Antimicrobial Evaluation of Nitazoxanide-Based Analogues: Identification of Selective and Broad Spectrum Activity.

Published in:

ChemMedChem, 2011, v. 6, n. 2, p. 362, doi. 10.1002/cmdc.201000475

By:

Ballard, T. Eric;
Wang, Xia;
Olekhnovich, Igor;
Koerner, Taylor;
Seymour, Craig;
Salamoun, Joseph;
Warthan, Michelle;
Hoffman, Paul S.;
Macdonald, Timothy L.

Publication type:

Article

Synthesis and in vitro/in vivo Evaluation of the Antitrypanosomal Activity of 3-Bromoacivicin, a Potent CTP Synthetase Inhibitor.

Published in:

ChemMedChem, 2011, v. 6, n. 2, p. 329, doi. 10.1002/cmdc.201000417

By:

Conti, Paola;
Pinto, Andrea;
Wong, Pui E.;
Major, Louise L.;
Tamborini, Lucia;
Iannuzzi, Maria C.;
De Micheli, Carlo;
Barrett, Michael P.;
Smith, Terry K.

Publication type:

Article

Tetrahydrobenzothiophene Derivatives: Conformationally Restricted Inhibitors of Type II Dehydroquinase.

Published in:

ChemMedChem, 2011, v. 6, n. 2, p. 266, doi. 10.1002/cmdc.201000343

By:

Paz, Sonia;
Tizón, Lorena;
Otero, José M.;
Llamas-Saiz, Antonio L.;
Fox, Gavin C.;
van Raaij, Mark J.;
Lamb, Heather;
Hawkins, Alastair R.;
Lapthorn, Adrian J.;
Castedo, Luis;
González-Bello, Concepción

Publication type:

Article

Preview: ChemMedChem 3/2011.

Published in:: ChemMedChem, 2011, v. 6, n. 2, p. 379, doi. 10.1002/cmdc.201190004
Publication type:: Article

Maurizio Botta.

Published in:: ChemMedChem, 2011, v. 6, n. 2, p. 227, doi. 10.1002/cmdc.201000500
Publication type:: Article

Reactions of Antimalarial Peroxides with Each of Leucomethylene Blue and Dihydroflavins: Flavin Reductase and the Cofactor Model Exemplified.

Published in:

ChemMedChem, 2011, v. 6, n. 2, p. 279, doi. 10.1002/cmdc.201000508

By:

Haynes, Richard K.;
Cheu, Kwan-Wing;
Tang, Maggie Mei-Ki;
Chen, Min-Jiao;
Guo, Zu-Feng;
Guo, Zhi-Hong;
Coghi, Paolo;
Monti, Diego

Publication type:

Article

Modified 5′-Trityl Nucleosides as Inhibitors of Plasmodium falciparum dUTPase.

Published in:

ChemMedChem, 2011, v. 6, n. 2, p. 309, doi. 10.1002/cmdc.201000445

By:

Ruda, Gian Filippo;
Nguyen, Corinne;
Ziemkowski, Przemysław;
Felczak, Krzysztof;
Kasinathan, Ganasan;
Musso-Buendia, Alexander;
Sund, Christian;
Zhou, Xiao Xiong;
Kaiser, Marcel;
Ruiz-Pérez, Luis M.;
Brun, Reto;
Kulikowski, Tadeusz;
Johansson, Nils Gunnar;
González-Pacanowska, Dolores;
Gilbert, Ian H.

Publication type:

Article

Spotlights on our sister journals: ChemMedChem 2/2011.

Published in:: ChemMedChem, 2011, v. 6, n. 2, p. 224, doi. 10.1002/cmdc.201190003
Publication type:: Article

A Versatile and Practical Synthesis toward the Development of Novel HIV-1 Integrase Inhibitors.

Published in:

ChemMedChem, 2011, v. 6, n. 2, p. 343, doi. 10.1002/cmdc.201000510

By:

Rinaldi, Marta;
Tintori, Cristina;
Franchi, Luigi;
Vignaroli, Giulia;
Innitzer, Anna;
Massa, Silvio;
Esté, José A.;
Gonzalo, Encarna;
Christ, Frauke;
Debyser, Zeger;
Botta, Maurizio

Publication type:

Article

Graphical Abstract: ChemMedChem 2/2011.

Published in:: ChemMedChem, 2011, v. 6, n. 2, p. 216, doi. 10.1002/cmdc.201190002
Publication type:: Article

Combating Cystic Fibrosis: In Search for CF Transmembrane Conductance Regulator (CFTR) Modulators.

Published in:

ChemMedChem, 2011, v. 6, n. 2, p. 243, doi. 10.1002/cmdc.201000488

By:

Noy, Efrat;
Senderowitz, Hanoch

Publication type:

Article

Location, Location, Location.

Published in:

ChemMedChem, 2011, v. 6, n. 2, p. 211, doi. 10.1002/cmdc.200000528

By:

Kozikowski, Alan;
Botta, Maurizio

Publication type:

Article

Potent and Selective Inhibition of Cysteine Proteases from Plasmodium falciparum and Trypanosoma brucei.

Published in:

ChemMedChem, 2011, v. 6, n. 2, p. 273, doi. 10.1002/cmdc.201000449

By:

Ehmke, Veronika;
Heindl, Cornelia;
Rottmann, Matthias;
Freymond, Céline;
Schweizer, W. Bernd;
Brun, Reto;
Stich, August;
Schirmeister, Tanja;
Diederich, François

Publication type:

Article