Works matching IS 18607179 AND DT 2011 AND VI 6 AND IP 12

Results: 31

Inside Cover: A Heterodimeric Glucuronide Prodrug for Cancer Tritherapy: the Double Role of the Chemical Amplifier (ChemMedChem 12/2011).

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2114, doi. 10.1002/cmdc.201190053

By:

Grinda, Marion;
Clarhaut, Jonathan;
Tranoy-Opalinski, Isabelle;
Renoux, Brigitte;
Monvoisin, Arnaud;
Cronier, Laurent;
Papot, Sébastien

Publication type:

Article

Protein Kinases as Drug Targets. Edited by Bert Klebl, Gerhard Müller and Michael Hamacher.

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2325, doi. 10.1002/cmdc.201100386

By:

Dreyer, Matthias

Publication type:

Article

Structure-Based Discovery of Allosteric Modulators of Two Related Class B G-Protein-Coupled Receptors.

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2159, doi. 10.1002/cmdc.201100317

By:

de Graaf, Chris;
Rein, Chantal;
Piwnica, David;
Giordanetto, Fabrizio;
Rognan, Didier

Publication type:

Article

New Prodrugs of the Antiprotozoal Drug Pentamidine.

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2233, doi. 10.1002/cmdc.201100422

By:

Kotthaus, Joscha;
Kotthaus, Jürke;
Schade, Dennis;
Schwering, Ulrike;
Hungeling, Helen;
Müller-Fielitz, Helge;
Raasch, Walter;
Clement, Bernd

Publication type:

Article

Synthesis and Anti-HIV Activity of Aryl-2-[(4-cyanophenyl)amino]-4-pyrimidinone hydrazones as Potent Non-nucleoside Reverse Transcriptase Inhibitors.

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2225, doi. 10.1002/cmdc.201100334

By:

Ma, Xiao-Dong;
Yang, Shi-Qiong;
Gu, Shuang-Xi;
He, Qiu-Qin;
Chen, Fen-Er;
De Clercq, Erik;
Balzarini, Jan;
Pannecouque, Christophe

Publication type:

Article

J. Bajorath.

Published in:: ChemMedChem, 2011, v. 6, n. 12, p. 2131, doi. 10.1002/cmdc.201100415
Publication type:: Article

Evaluation of Platinum-Ethacrynic Acid Conjugates in the Treatment of Mesothelioma.

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2287, doi. 10.1002/cmdc.201100426

By:

Zanellato, Ilaria;
Bonarrigo, Ilaria;
Sardi, Manuele;
Alessio, Manuela;
Gabano, Elisabetta;
Ravera, Mauro;
Osella, Domenico

Publication type:

Article

Targeted Delivery of Small and Macromolecular Drugs. Edited by Ajit S. Narang and Ram I. Mahato.

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2323, doi. 10.1002/cmdc.201100352

By:

Caliceti, Paolo

Publication type:

Article

Cover Picture: Urolithin as a Converging Scaffold Linking Ellagic acid and Coumarin Analogues: Design of Potent Protein Kinase CK2 Inhibitors (ChemMedChem 12/2011).

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2113, doi. 10.1002/cmdc.201190052

By:

Cozza, Giorgio;
Gianoncelli, Alessandra;
Bonvini, Paolo;
Zorzi, Elisa;
Pasquale, Riccardo;
Rosolen, Angelo;
Pinna, Lorenzo A.;
Meggio, Flavio;
Zagotto, Giuseppe;
Moro, Stefano

Publication type:

Article

Complementary Screening Techniques Yielded Fragments that Inhibit the Phosphatase Activity of Soluble Epoxide Hydrolase.

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2146, doi. 10.1002/cmdc.201100433

By:

Hahn, Steffen;
Achenbach, Janosch;
Buscató, Estella;
Klingler, Franca-Maria;
Schroeder, Mirjam;
Meirer, Karin;
Hieke, Martina;
Heering, Jan;
Barbosa-Sicard, Eduardo;
Loehr, Frank;
Fleming, Ingrid;
Doetsch, Volker;
Schubert-Zsilavecz, Manfred;
Steinhilber, Dieter;
Proschak, Ewgenij

Publication type:

Article

An Old NSAID Revisited: Crystal Structure of Aldose Reductase in Complex with Sulindac at 1.0 Å Supports a Novel Mechanism for its Anticancer and Antiproliferative Effects.

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2155, doi. 10.1002/cmdc.201100374

By:

Steuber, Holger

Publication type:

Article

Pyrolo[1,2:4,5]-1,4-dioxopyrazino[1,2:1,6]pyrido[3,4- b]indoles: A Group of Urokinase Inhibitors, their Synthesis, and Stereochemistry-Dependent Activity.

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2312, doi. 10.1002/cmdc.201100345

By:

Liu, Jiawang;
Wang, Yuji;
Yang, Yifan;
Jiang, Xueyun;
Zhao, Ming;
Wang, Wenjing;
Wu, Guofeng;
Wu, Jianhui;
Zheng, Meiqing;
Peng, Shiqi

Publication type:

Article

Evaluation of 4,5-Disubstituted-2-Aminoimidazole-Triazole Conjugates for Antibiofilm/Antibiotic Resensitization Activity Against MRSA and Acinetobacter baumannii.

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2243, doi. 10.1002/cmdc.201100316

By:

Su, Zhaoming;
Peng, Lingling;
Worthington, Roberta J.;
Melander, Christian

Publication type:

Article

Preview: ChemMedChem 1/2012.

Published in:: ChemMedChem, 2011, v. 6, n. 12, p. 2327, doi. 10.1002/cmdc.201190056
Publication type:: Article

Urolithin as a Converging Scaffold Linking Ellagic acid and Coumarin Analogues: Design of Potent Protein Kinase CK2 Inhibitors.

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2273, doi. 10.1002/cmdc.201100338

By:

Cozza, Giorgio;
Gianoncelli, Alessandra;
Bonvini, Paolo;
Zorzi, Elisa;
Pasquale, Riccardo;
Rosolen, Angelo;
Pinna, Lorenzo A.;
Meggio, Flavio;
Zagotto, Giuseppe;
Moro, Stefano

Publication type:

Article

4-Substituted Thioquinolines and Thiazoloquinolines: Potent, Selective, and Tween-80 in vitro Dependent Families of Antitubercular Agents with Moderate in vivo Activity.

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2252, doi. 10.1002/cmdc.201100309

By:

Escribano, Jaime;
Rivero-Hernández, Cristina;
Rivera, Hilda;
Barros, David;
Castro-Pichel, Julia;
Pérez-Herrán, Esther;
Mendoza-Losana, Alfonso;
Angulo-Barturen, Íñigo;
Ferrer-Bazaga, Santiago;
Jiménez-Navarro, Elena;
Ballell, Lluís

Publication type:

Article

The Discovery of Compounds That Stimulate the Activity of Kallikrein-Related Peptidase 3 (KLK3).

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2170, doi. 10.1002/cmdc.201100349

By:

Härkönen, Henna H.;
Mattsson, Johanna M.;
Määttä, Juha A. E.;
Stenman, Ulf-Håkan;
Koistinen, Hannu;
Matero, Sanni;
Windshügel, Björn;
Poso, Antti;
Lahtela-Kakkonen, Maija

Publication type:

Article

Corrigendum: The Discovery of Compounds That Stimulate the Activity of Kallikrein-Related Peptidase 3 (KLK3).

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2123, doi. 10.1002/cmdc.201100461

By:

Härkönen, Henna H.;
Mattsson, Johanna M.;
Määttä, Juha A. E.;
Stenman, Ulf-Håkan;
Koistinen, Hannu;
Matero, Sanni;
Windshügel, Björn;
Poso, Antti;
Lahtela-Kakkonen, Maija

Publication type:

Article

Docking Analysis and Resistance Evaluation of Clinically Relevant Mutations Associated with the HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors Nevirapine, Efavirenz and Etravirine.

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2203, doi. 10.1002/cmdc.201100362

By:

Alcaro, Stefano;
Alteri, Claudia;
Artese, Anna;
Ceccherini-Silberstein, Francesca;
Costa, Giosuè;
Ortuso, Francesco;
Bertoli, Ada;
Forbici, Federica;
Santoro, Maria Mercedes;
Parrotta, Lucia;
Flandre, Philippe;
Masquelier, Bernard;
Descamps, Diane;
Calvez, Vincent;
Marcelin, Anne-Genevieve;
Perno, Carlo Federico;
Sing, Tobias;
Svicher, Valentina

Publication type:

Article

Curaxins: A New Family of Non-genotoxic Multitargeted Anticancer Agents.

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2133, doi. 10.1002/cmdc.201100476

By:

Di Bussolo, Valeria;
Minutolo, Filippo

Publication type:

Article

Identification of Inhibitors of the Leishmania cdc2-Related Protein Kinase CRK3.

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2214, doi. 10.1002/cmdc.201100344

By:

Cleghorn, Laura A. T.;
Woodland, Andrew;
Collie, Iain T.;
Torrie, Leah S.;
Norcross, Neil;
Luksch, Torsten;
Mpamhanga, Chido;
Walker, Roderick G.;
Mottram, Jeremy C.;
Brenk, Ruth;
Frearson, Julie A.;
Gilbert, Ian H.;
Wyatt, Paul G.

Publication type:

Article

Modulation of the Biological Activity of microRNA-210 with Peptide Nucleic Acids (PNAs).

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2192, doi. 10.1002/cmdc.201100270

By:

Fabbri, Enrica;
Manicardi, Alex;
Tedeschi, Tullia;
Sforza, Stefano;
Bianchi, Nicoletta;
Brognara, Eleonora;
Finotti, Alessia;
Breveglieri, Giulia;
Borgatti, Monica;
Corradini, Roberto;
Marchelli, Rosangela;
Gambari, Roberto

Publication type:

Article

Novel Rhein Analogues as Potential Anticancer Agents.

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2294, doi. 10.1002/cmdc.201100384

By:

Yang, Xiaochuan;
Sun, Guojing;
Yang, Chunhao;
Wang, Binghe

Publication type:

Article

A Heterodimeric Glucuronide Prodrug for Cancer Tritherapy: the Double Role of the Chemical Amplifier.

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2137, doi. 10.1002/cmdc.201100355

By:

Grinda, Marion;
Clarhaut, Jonathan;
Tranoy-Opalinski, Isabelle;
Renoux, Brigitte;
Monvoisin, Arnaud;
Cronier, Laurent;
Papot, Sébastien

Publication type:

Article

Activity Profile Sequences: a Concept to Account for the Progression of Compound Activity in Target Space and to Extract SAR Information from Analogue Series with Multiple Target Annotations.

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2150, doi. 10.1002/cmdc.201100395

By:

Hu, Ye;
Bajorath, Jürgen

Publication type:

Article

Spotlights on our sister journals: ChemMedChem 12/2011.

Published in:: ChemMedChem, 2011, v. 6, n. 12, p. 2128, doi. 10.1002/cmdc.201190055
Publication type:: Article

From Catalysts to Bioactive Organometallics: Do Grubbs Catalysts Trigger Biological Effects?

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2142, doi. 10.1002/cmdc.201100308

By:

Oehninger, Luciano;
Alborzinia, Hamed;
Ludewig, Stephanie;
Baumann, Knut;
Wölfl, Stefan;
Ott, Ingo

Publication type:

Article

Development of Isoxazoline-Containing Peptidomimetics as Dual αvβ3 and α5β1 Integrin Ligands.

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2264, doi. 10.1002/cmdc.201100372

By:

Tolomelli, Alessandra;
Gentilucci, Luca;
Mosconi, Elisa;
Viola, Angelo;
Dattoli, Samantha Deianira;
Baiula, Monica;
Spampinato, Santi;
Belvisi, Laura;
Civera, Monica

Publication type:

Article

Graphical Abstract: ChemMedChem 12/2011.

Published in:: ChemMedChem, 2011, v. 6, n. 12, p. 2115, doi. 10.1002/cmdc.201190054
Publication type:: Article

B-Ring-Modified isoCombretastatin A-4 Analogues Endowed with Interesting Anticancer Activities.

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2179, doi. 10.1002/cmdc.201100325

By:

Hamze, Abdallah;
Rasolofonjatovo, Evelia;
Provot, Olivier;
Mousset, Céline;
Veau, Damien;
Rodrigo, Jordi;
Bignon, Jérôme;
Liu, Jian-Miao;
Wdzieczak-Bakala, Joanna;
Thoret, Sylviane;
Dubois, Joëlle;
Brion, Jean-Daniel;
Alami, Mouad

Publication type:

Article

Substructure-Based Virtual Screening for Adenosine A2A Receptor Ligands.

Published in:

ChemMedChem, 2011, v. 6, n. 12, p. 2302, doi. 10.1002/cmdc.201100369

By:

van der Horst, Eelke;
van der Pijl, Rianne;
Mulder-Krieger, Thea;
Bender, Andreas;
IJzerman, Adriaan P.

Publication type:

Article

Works matching IS 18607179 AND DT 2011 AND VI 6 AND IP 12

Inside Cover: A Heterodimeric Glucuronide Prodrug for Cancer Tritherapy: the Double Role of the Chemical Amplifier (ChemMedChem 12/2011).

Protein Kinases as Drug Targets. Edited by Bert Klebl, Gerhard Müller and Michael Hamacher.

Structure-Based Discovery of Allosteric Modulators of Two Related Class B G-Protein-Coupled Receptors.

New Prodrugs of the Antiprotozoal Drug Pentamidine.

Synthesis and Anti-HIV Activity of Aryl-2-[(4-cyanophenyl)amino]-4-pyrimidinone hydrazones as Potent Non-nucleoside Reverse Transcriptase Inhibitors.

J. Bajorath.

Evaluation of Platinum-Ethacrynic Acid Conjugates in the Treatment of Mesothelioma.

Targeted Delivery of Small and Macromolecular Drugs. Edited by Ajit S. Narang and Ram I. Mahato.

Cover Picture: Urolithin as a Converging Scaffold Linking Ellagic acid and Coumarin Analogues: Design of Potent Protein Kinase CK2 Inhibitors (ChemMedChem 12/2011).

Complementary Screening Techniques Yielded Fragments that Inhibit the Phosphatase Activity of Soluble Epoxide Hydrolase.

An Old NSAID Revisited: Crystal Structure of Aldose Reductase in Complex with Sulindac at 1.0 Å Supports a Novel Mechanism for its Anticancer and Antiproliferative Effects.

Pyrolo[1,2:4,5]-1,4-dioxopyrazino[1,2:1,6]pyrido[3,4- b]indoles: A Group of Urokinase Inhibitors, their Synthesis, and Stereochemistry-Dependent Activity.

Evaluation of 4,5-Disubstituted-2-Aminoimidazole-Triazole Conjugates for Antibiofilm/Antibiotic Resensitization Activity Against MRSA and Acinetobacter baumannii.

Preview: ChemMedChem 1/2012.

Urolithin as a Converging Scaffold Linking Ellagic acid and Coumarin Analogues: Design of Potent Protein Kinase CK2 Inhibitors.

4-Substituted Thioquinolines and Thiazoloquinolines: Potent, Selective, and Tween-80 in vitro Dependent Families of Antitubercular Agents with Moderate in vivo Activity.

The Discovery of Compounds That Stimulate the Activity of Kallikrein-Related Peptidase 3 (KLK3).

Corrigendum: The Discovery of Compounds That Stimulate the Activity of Kallikrein-Related Peptidase 3 (KLK3).

Docking Analysis and Resistance Evaluation of Clinically Relevant Mutations Associated with the HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors Nevirapine, Efavirenz and Etravirine.

Curaxins: A New Family of Non-genotoxic Multitargeted Anticancer Agents.

Identification of Inhibitors of the Leishmania cdc2-Related Protein Kinase CRK3.

Modulation of the Biological Activity of microRNA-210 with Peptide Nucleic Acids (PNAs).

Novel Rhein Analogues as Potential Anticancer Agents.

A Heterodimeric Glucuronide Prodrug for Cancer Tritherapy: the Double Role of the Chemical Amplifier.

Activity Profile Sequences: a Concept to Account for the Progression of Compound Activity in Target Space and to Extract SAR Information from Analogue Series with Multiple Target Annotations.

Spotlights on our sister journals: ChemMedChem 12/2011.

From Catalysts to Bioactive Organometallics: Do Grubbs Catalysts Trigger Biological Effects?

Development of Isoxazoline-Containing Peptidomimetics as Dual α<sub>v</sub>β<sub>3</sub> and α<sub>5</sub>β<sub>1</sub> Integrin Ligands.

Graphical Abstract: ChemMedChem 12/2011.

B-Ring-Modified isoCombretastatin A-4 Analogues Endowed with Interesting Anticancer Activities.

Substructure-Based Virtual Screening for Adenosine A<sub>2A</sub> Receptor Ligands.