Works matching IS 18607179 AND DT 2010 AND VI 5 AND IP 5

Results: 22

A Highly Potent and Selective Caspase 1 Inhibitor that Utilizes a Key 3-Cyanopropanoic Acid Moiety.

Published in:

ChemMedChem, 2010, v. 5, n. 5, p. 730, doi. 10.1002/cmdc.200900531

By:

Boxer, Matthew B.;
Quinn, Amy M.;
Shen, Min;
Jadhav, Ajit;
Leister, William;
Simeonov, Anton;
Auld, Douglas S.;
Thomas, Craig J.

Publication type:

Article

Structure of the Glucocorticoid Receptor, a Flexible Protein That Can Adapt to Different Ligands.

Published in:

ChemMedChem, 2010, v. 5, n. 5, p. 649, doi. 10.1002/cmdc.201000014

By:

Veleiro, Adriana S.;
Alvarez, Lautaro D.;
Eduardo, Silvina L.;
Burton, Gerardo

Publication type:

Article

Cover Picture: Molecular Editing of Kinase-Targeting Resorcylic Acid Lactones (RAL): Fluoroenone RAL (ChemMedChem 5/2010).

Published in:

ChemMedChem, 2010, v. 5, n. 5, p. 633, doi. 10.1002/cmdc.201090015

By:

Jogireddy, Rajamalleswaramma;
Barluenga, Sofia;
Winssinger, Nicolas

Publication type:

Article

Preview: ChemMedChem 6/2010.

Published in:: ChemMedChem, 2010, v. 5, n. 5, p. 795, doi. 10.1002/cmdc.201090019
Publication type:: Article

Aminocarnitine Ureidic Derivatives as Inhibitors of Carnitine Palmitoyltransferase I.

Published in:

ChemMedChem, 2010, v. 5, n. 5, p. 666, doi. 10.1002/cmdc.200900535

By:

Tassoni, Emanuela;
Conti, Roberto;
Gallo, Grazia;
Vincenti, Silvia;
Dell'Uomo, Natalina;
Mastrofrancesco, Lucilla;
Ricciolini, Rita;
Cabri, Walter;
Carminati, Paolo;
Giannessi, Fabio

Publication type:

Article

Molecular Editing of Kinase-Targeting Resorcylic Acid Lactones (RAL): Fluoroenone RAL.

Published in:

ChemMedChem, 2010, v. 5, n. 5, p. 670, doi. 10.1002/cmdc.201000047

By:

Jogireddy, Rajamalleswaramma;
Barluenga, Sofia;
Winssinger, Nicolas

Publication type:

Article

Synthesis and Properties of a Photoactivatable Analogue of Psychosine (β-Galactosylsphingosine).

Published in:

ChemMedChem, 2010, v. 5, n. 5, p. 682, doi. 10.1002/cmdc.201000018

By:

Lankalapalli, Ravi S.;
Baksa, Attila;
Liliom, Károly;
Bittman, Robert

Publication type:

Article

Spotlights on our sister journals: ChemMedChem 5/2010.

Published in:: ChemMedChem, 2010, v. 5, n. 5, p. 644, doi. 10.1002/cmdc.201090018
Publication type:: Article

Chiral Aryloxyalkylamines: Selective 5-HT1B/1D Activation and Analgesic Activity.

Published in:

ChemMedChem, 2010, v. 5, n. 5, p. 696, doi. 10.1002/cmdc.200900530

By:

Carocci, Alessia;
Lentini, Giovanni;
Catalano, Alessia;
Cavalluzzi, Maria Maddalena;
Bruno, Claudio;
Muraglia, Marilena;
Colabufo, Nicola Antonio;
Galeotti, Nicoletta;
Corbo, Filomena;
Matucci, Rosanna;
Ghelardini, Carla;
Franchini, Carlo

Publication type:

Article

Identification of Tri- and Tetracyclic Pyrimidinediones as Sirtuin Inhibitors.

Published in:

ChemMedChem, 2010, v. 5, n. 5, p. 674, doi. 10.1002/cmdc.201000030

By:

Rotili, Dante;
Tarantino, Domenico;
Carafa, Vincenzo;
Lara, Ester;
Meade, Sarah;
Botta, Giorgia;
Nebbioso, Angela;
Schemies, Jörg;
Jung, Manfred;
Kazantsev, Aleksey G.;
Esteller, Manel;
Fraga, Mario F.;
Altucci, Lucia;
Mai, Antonello

Publication type:

Article

Azides Derived from Colchicine and their Use in Library Synthesis: a Practical Entry to New Bioactive Derivatives of an Old Natural Drug.

Published in:

ChemMedChem, 2010, v. 5, n. 5, p. 661, doi. 10.1002/cmdc.201000063

By:

Nicolaus, Norman;
Zapke, Janet;
Riesterer, Philipp;
Neudörfl, Jörg-Martin;
Prokop, Aram;
Oschkinat, Hartmut;
Schmalz, Hans-Günther

Publication type:

Article

Prospective Validation of a Comprehensive In silico hERG Model and its Applications to Commercial Compound and Drug Databases.

Published in:

ChemMedChem, 2010, v. 5, n. 5, p. 716, doi. 10.1002/cmdc.201000024

By:

Doddareddy, Munikumar R.;
Klaasse, Elisabeth C.;
Shagufta;
IJzerman, Adriaan P.;
Bender, Andreas

Publication type:

Article

Adenosine and 2′-Deoxyadenosine Modified with Boron Cluster Pharmacophores as New Classes of Human Blood Platelet Function Modulators.

Published in:

ChemMedChem, 2010, v. 5, n. 5, p. 749, doi. 10.1002/cmdc.201000075

By:

Bednarska, Katarzyna;
Olejniczak, Agnieszka B.;
Wojtczak, Błażej A.;
Sułowska, Zofia;
Leśnikowski, Zbigniew J.

Publication type:

Article

Graphical Abstract: ChemMedChem 5/2010.

Published in:: ChemMedChem, 2010, v. 5, n. 5, p. 635, doi. 10.1002/cmdc.201090017
Publication type:: Article

Design, Synthesis, and Preliminary Biological Evaluation of Pyrrolo[3,4- c]quinolin-1-one and Oxoisoindoline Derivatives as Aggrecanase Inhibitors.

Published in:

ChemMedChem, 2010, v. 5, n. 5, p. 739, doi. 10.1002/cmdc.200900523

By:

Cappelli, Andrea;
Nannicini, Chiara;
Valenti, Salvatore;
Giuliani, Germano;
Anzini, Maurizio;
Mennuni, Laura;
Giordani, Antonio;
Caselli, Gianfranco;
Stasi, Luigi Piero;
Makovec, Francesco;
Giorgi, Gianluca;
Vomero, Salvatore

Publication type:

Article

Radiofluorinated Pyrimidine-2,4,6-triones as Molecular Probes for Noninvasive MMP-Targeted Imaging.

Published in:

ChemMedChem, 2010, v. 5, n. 5, p. 777, doi. 10.1002/cmdc.201000013

By:

Breyholz, Hans-Jörg;
Wagner, Stefan;
Faust, Andreas;
Riemann, Burkhard;
Höltke, Carsten;
Hermann, Sven;
Schober, Otmar;
Schäfers, Michael;
Kopka, Klaus

Publication type:

Article

Triazolyl Azabicyclo[3.1.0]hexanes: a Class of Potent and Selective Dopamine D3 Receptor Antagonists.

Published in:

ChemMedChem, 2010, v. 5, n. 5, p. 705, doi. 10.1002/cmdc.201000026

By:

Bonanomi, Giorgio;
Braggio, Simone;
Capelli, Anna Maria;
Checchia, Anna;
Di Fabio, Romano;
Marchioro, Carla;
Tarsi, Luca;
Tedesco, Giovanna;
Terreni, Silvia;
Worby, Angela;
Heibreder, Christian;
Micheli, Fabrizio

Publication type:

Article

Inside Cover: A Highly Potent and Selective Caspase 1 Inhibitor that Utilizes a Key 3-Cyanopropanoic Acid Moiety (ChemMedChem 5/2010).

Published in:

ChemMedChem, 2010, v. 5, n. 5, p. 634, doi. 10.1002/cmdc.201090016

By:

Boxer, Matthew B.;
Quinn, Amy M.;
Shen, Min;
Jadhav, Ajit;
Leister, William;
Simeonov, Anton;
Auld, Douglas S.;
Thomas, Craig J.

Publication type:

Article

Highly Potent Modulation of GABAA Receptors by Valerenic Acid Derivatives.

Published in:

ChemMedChem, 2010, v. 5, n. 5, p. 678, doi. 10.1002/cmdc.201000062

By:

Kopp, Sascha;
Baur, Roland;
Sigel, Erwin;
Möhler, Hanns;
Altmann, Karl-Heinz

Publication type:

Article

Design, Synthesis, and Biological Evaluation of 3-Benzazepin-1-ols as NR2B-Selective NMDA Receptor Antagonists.

Published in:

ChemMedChem, 2010, v. 5, n. 5, p. 687, doi. 10.1002/cmdc.201000005

By:

Tewes, Bastian;
Frehland, Bastian;
Schepmann, Dirk;
Schmidtke, Kai-Uwe;
Winckler, Thomas;
Wünsch, Bernhard

Publication type:

Article

An in vitro Assay to Measure Targeted Drug Delivery to Bone Mineral.

Published in:

ChemMedChem, 2010, v. 5, n. 5, p. 770, doi. 10.1002/cmdc.201000016

By:

Jahnke, Wolfgang;
Henry, Chrystèle

Publication type:

Article

Synthesis and in vitro and in vivo Antifungal Activity of the Hydroxy Metabolites of Saperconazole.

Published in:

ChemMedChem, 2010, v. 5, n. 5, p. 757, doi. 10.1002/cmdc.201000040

By:

Meerpoel, Lieven;
Heeres, Jan;
Backx, Leo J. J.;
Van der Veken, Louis J. E.;
Hendrickx, Rob;
Corens, David;
De Groot, Alex;
Leurs, Stef;
Van der Eycken, Luc;
Weerts, Johan;
Luyts, Paul;
Van Gerven, Frans;
Woestenborghs, Filip A. A.;
Van Breda, Andre;
Oris, Michel;
van Dorsselaer, Pascal;
Willemsens, Gustaaf H. M.;
Bellens, Danny;
Marichal, Patrick J. M. G.;
Vanden Bossche, Hugo F.

Publication type:

Article

Works matching IS 18607179 AND DT 2010 AND VI 5 AND IP 5

A Highly Potent and Selective Caspase 1 Inhibitor that Utilizes a Key 3-Cyanopropanoic Acid Moiety.

Structure of the Glucocorticoid Receptor, a Flexible Protein That Can Adapt to Different Ligands.

Cover Picture: Molecular Editing of Kinase-Targeting Resorcylic Acid Lactones (RAL): Fluoroenone RAL (ChemMedChem 5/2010).

Preview: ChemMedChem 6/2010.

Aminocarnitine Ureidic Derivatives as Inhibitors of Carnitine Palmitoyltransferase I.

Molecular Editing of Kinase-Targeting Resorcylic Acid Lactones (RAL): Fluoroenone RAL.

Synthesis and Properties of a Photoactivatable Analogue of Psychosine (β-Galactosylsphingosine).

Spotlights on our sister journals: ChemMedChem 5/2010.

Chiral Aryloxyalkylamines: Selective 5-HT<sub>1B/1D</sub> Activation and Analgesic Activity.

Identification of Tri- and Tetracyclic Pyrimidinediones as Sirtuin Inhibitors.

Azides Derived from Colchicine and their Use in Library Synthesis: a Practical Entry to New Bioactive Derivatives of an Old Natural Drug.

Prospective Validation of a Comprehensive In silico hERG Model and its Applications to Commercial Compound and Drug Databases.

Adenosine and 2′-Deoxyadenosine Modified with Boron Cluster Pharmacophores as New Classes of Human Blood Platelet Function Modulators.

Graphical Abstract: ChemMedChem 5/2010.

Design, Synthesis, and Preliminary Biological Evaluation of Pyrrolo[3,4- c]quinolin-1-one and Oxoisoindoline Derivatives as Aggrecanase Inhibitors.

Radiofluorinated Pyrimidine-2,4,6-triones as Molecular Probes for Noninvasive MMP-Targeted Imaging.

Triazolyl Azabicyclo[3.1.0]hexanes: a Class of Potent and Selective Dopamine D<sub>3</sub> Receptor Antagonists.

Inside Cover: A Highly Potent and Selective Caspase 1 Inhibitor that Utilizes a Key 3-Cyanopropanoic Acid Moiety (ChemMedChem 5/2010).

Highly Potent Modulation of GABA<sub>A</sub> Receptors by Valerenic Acid Derivatives.

Design, Synthesis, and Biological Evaluation of 3-Benzazepin-1-ols as NR2B-Selective NMDA Receptor Antagonists.

An in vitro Assay to Measure Targeted Drug Delivery to Bone Mineral.

Synthesis and in vitro and in vivo Antifungal Activity of the Hydroxy Metabolites of Saperconazole.