Works matching IS 18607179 AND DT 2009 AND VI 4 AND IP 12

Results: 28

Redox Signaling and Regulation in Biology and Medicine. Edited by Claus Jacob and Paul G. Winyard.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 2125, doi. 10.1002/cmdc.200900297

By:

Krauth-Siegel, R. Luise

Publication type:

Article

Modelling Atypical Small-Molecule Mimics of an Important Stem Cell Cytokine, Thrombopoietin.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 2002, doi. 10.1002/cmdc.200900340

By:

Tarasova, Anna;
Winkler, David A.

Publication type:

Article

Virtual Screening against p50 NF-κB Transcription Factor for the Identification of Inhibitors of the NF-κB-DNA Interaction and Expression of NF-κB Upregulated Genes.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 2024, doi. 10.1002/cmdc.200900362

By:

Piccagli, Laura;
Fabbri, Enrica;
Borgatti, Monica;
Bianchi, Nicoletta;
Bezzerri, Valentino;
Mancini, Irene;
Nicolis, Elena;
Dechecchi, Cristina M.;
Lampronti, Ilaria;
Cabrini, Giulio;
Gambari, Roberto

Publication type:

Article

Synthesis and Pharmacological Evaluation of Dimeric Follicle-Stimulating Hormone Receptor Antagonists.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 2098, doi. 10.1002/cmdc.200900344

By:

Bonger, Kimberly M.;
Hoogendoorn, Sascha;
van Koppen, Chris J.;
Timmers, Cornelis M.;
Overkleeft, Herman S.;
van der Marel, Gijsbert A.

Publication type:

Article

The Tertiary Amine Nitrogen Atom of Piperazine Sulfonamides as a Novel Determinant of Potent and Selective β3-Adrenoceptor Agonists.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 2080, doi. 10.1002/cmdc.200900292

By:

Perrone, Maria Grazia;
Bleve, Laura;
Santandrea, Ernesto;
Vitale, Paola;
Niso, Mauro;
Scilimati, Antonio

Publication type:

Article

[6,7]-Heterocycle-Fused 14-Hydroxymorphinan Derivatives: Design, Synthesis, and Opioid Receptor Activity.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 2103, doi. 10.1002/cmdc.200900308

By:

Li, Fuying;
Yin, Chenlei;
Chen, Jie;
Liu, Jinggen;
Xie, Xin;
Zhang, Ao

Publication type:

Article

2-Substituted-3-Dehydroquinic Acids as Potent Competitive Inhibitors of Type II Dehydroquinase.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 1980, doi. 10.1002/cmdc.200900319

By:

Prazeres, Verónica F. V.;
Castedo, Luis;
Lamb, Heather;
Hawkins, Alastair R.;
González-Bello, Concepción

Publication type:

Article

Fast Prediction of Cytochrome P450 Mediated Drug Metabolism.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 1965, doi. 10.1002/cmdc.200990059

By:

Rydberg, Patrik;
Vasanthanathan, Poongavanam;
Oostenbrink, Chris;
Olsen, Lars

Publication type:

Article

Preview: ChemMedChem 1/2010.

Published in:: ChemMedChem, 2009, v. 4, n. 12, p. 2135, doi. 10.1002/cmdc.200990061
Publication type:: Article

How to Replace the Residual Solvation Shell of Polar Active Site Residues to Achieve Nanomolar Inhibition of tRNA-Guanine Transglycosylase.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 2012, doi. 10.1002/cmdc.200900343

By:

Ritschel, Tina;
Kohler, Philipp C.;
Neudert, Gerd;
Heine, Andreas;
Diederich, François;
Klebe, Gerhard

Publication type:

Article

The Third Histamine Receptor. Edited by Divya Vohora.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 2126, doi. 10.1002/cmdc.200900428

By:

Provins, Laurent

Publication type:

Article

Investigation of Trypanothione Reductase as a Drug Target in Trypanosoma brucei.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 2060, doi. 10.1002/cmdc.200900262

By:

Spinks, Daniel;
Shanks, Emma J.;
Cleghorn, Laura A. T.;
McElroy, Stuart;
Jones, Deuan;
James, Daniel;
Fairlamb, Alan H.;
Frearson, Julie A.;
Wyatt, Paul G.;
Gilbert, Ian H.

Publication type:

Article

Aryldiketo Acids Have Antibacterial Activity Against MDR Staphylococcus aureus Strains: Structural Insights Based on Similarity and Molecular Interaction Fields.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 1971, doi. 10.1002/cmdc.200900273

By:

Drakulić, Branko J.;
Stavri, Michael;
Gibbons, Simon;
Žižak, Željko S.;
Verbić, Tatjana Ž.;
Juranić, Ivan O.;
Zloh, Mire

Publication type:

Article

Synthesis and Pharmacological Evaluation of SNC80 Analogues with a Bridged Piperazine Ring.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 2111, doi. 10.1002/cmdc.200900358

By:

Holl, Ralph;
Jung, Bettina;
Schepmann, Dirk;
Humpf, Hans-Ulrich;
Grünert, Renate;
Bednarski, Patrick J.;
Englberger, Werner;
Wünsch, Bernhard

Publication type:

Article

Graphical Abstract: ChemMedChem 12/2009.

Published in:: ChemMedChem, 2009, v. 4, n. 12, p. 1959, doi. 10.1002/cmdc.200990058
Publication type:: Article

Spotlights on our sister journals: ChemMedChem 12/2009.

Published in:: ChemMedChem, 2009, v. 4, n. 12, p. 1968, doi. 10.1002/cmdc.200990060
Publication type:: Article

Interaction of Artemisinins with Oxyhemoglobin Hb-FeII, Hb-FeII, CarboxyHb-FeII, Heme-FeII, and Carboxyheme FeII: Significance for Mode of Action and Implications for Therapy of Cerebral Malaria.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 2045, doi. 10.1002/cmdc.200900342

By:

Coghi, Paolo;
Basilico, Nicoletta;
Taramelli, Donatella;
Chan, Wing-Chi;
Haynes, Richard K.;
Monti, Diego

Publication type:

Article

Fluorine in Medicinal Chemistry and Chemical Biology. Edited by Iwao Ojima.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 2124, doi. 10.1002/cmdc.200900306

By:

Fustero, Santos

Publication type:

Article

A Practical Total Synthesis of the Microbial Alkaline Proteinase Inhibitor (MAPI).

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 2054, doi. 10.1002/cmdc.200900346

By:

Haebich, Dieter;
Hillisch, Alexander;
El Sheikh, Sherif

Publication type:

Article

Thermodynamic Optimisation in Drug Discovery: A Case Study using Carbonic Anhydrase Inhibitors.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 1985, doi. 10.1002/cmdc.200900386

By:

Scott, Andrew D.;
Phillips, Chris;
Alex, Alexander;
Flocco, Maria;
Bent, Andrew;
Randall, Amy;
O'Brien, Ronan;
Damian, Luminita;
Jones, Lyn H.

Publication type:

Article

Inside Cover: Synthesis, Inhibition Potency, Binding Mode, and Antiprotozoal Activities of Fluorescent Inhibitors of Trypanothione Reductase Based on Mepacrine-Conjugated Diaryl Sulfide Scaffolds (ChemMedChem 12/2009).

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 1958, doi. 10.1002/cmdc.200990057

By:

Eberle, Christian;
Burkhard, Johannes A.;
Stump, Bernhard;
Kaiser, Marcel;
Brun, Reto;
Krauth-Siegel, R. Luise;
Diederich, François

Publication type:

Article

Ring-Extended Derivatives of Gramicidin S with Furanoid Sugar Amino Acids in the Turn Region Have Enhanced Antimicrobial Activity.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 1976, doi. 10.1002/cmdc.200900379

By:

Knijnenburg, Annemiek D.;
Spalburg, Emile;
de Neeling, Albert J.;
Mars-Groenendijk, Roos H.;
Noort, Daan;
Grotenbreg, Gijsbert M.;
van der Marel, Gijsbert A.;
Overkleeft, Herman S.;
Overhand, Mark

Publication type:

Article

Genomics in Drug Discovery and Development. By Dimitri Semizarov and Eric Blomme.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 2126, doi. 10.1002/cmdc.200900400

By:

Knapp, Stefan

Publication type:

Article

Cancer Chemotherapy: Basic Science to the Clinic. By Rachel Airley.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 2123, doi. 10.1002/cmdc.200900323

By:

Altmann, Karl-Heinz

Publication type:

Article

Fast Prediction of Cytochrome P450 Mediated Drug Metabolism.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 2070, doi. 10.1002/cmdc.200900363

By:

Rydberg, Patrik;
Vasanthanathan, Poongavanam;
Oostenbrink, Chris;
Olsen, Lars

Publication type:

Article

Cover Picture: Interaction of Artemisinins with Oxyhemoglobin Hb-FeII, Hb-FeII, CarboxyHb-FeII, Heme-FeII, and Carboxyheme FeII: Significance for Mode of Action and Implications for Therapy of Cerebral Malaria (ChemMedChem 12/2009)

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 1957, doi. 10.1002/cmdc.200990056

By:

Coghi, Paolo;
Basilico, Nicoletta;
Taramelli, Donatella;
Chan, Wing-Chi;
Haynes, Richard K.;
Monti, Diego

Publication type:

Article

Synthesis, Inhibition Potency, Binding Mode, and Antiprotozoal Activities of Fluorescent Inhibitors of Trypanothione Reductase Based on Mepacrine-Conjugated Diaryl Sulfide Scaffolds.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 2034, doi. 10.1002/cmdc.200900327

By:

Eberle, Christian;
Burkhard, Johannes A.;
Stump, Bernhard;
Kaiser, Marcel;
Brun, Reto;
Krauth-Siegel, R. Luise;
Diederich, François

Publication type:

Article

Azetidinones as Zinc-Binding Groups to Design Selective HDAC8 Inhibitors.

Published in:

ChemMedChem, 2009, v. 4, n. 12, p. 1991, doi. 10.1002/cmdc.200900309

By:

Galletti, Paola;
Quintavalla, Arianna;
Ventrici, Caterina;
Giannini, Giuseppe;
Cabri, Walter;
Penco, Sergio;
Gallo, Grazia;
Vincenti, Silvia;
Giacomini, Daria

Publication type:

Article

Works matching IS 18607179 AND DT 2009 AND VI 4 AND IP 12

Redox Signaling and Regulation in Biology and Medicine. Edited by Claus Jacob and Paul G. Winyard.

Modelling Atypical Small-Molecule Mimics of an Important Stem Cell Cytokine, Thrombopoietin.

Virtual Screening against p50 NF-κB Transcription Factor for the Identification of Inhibitors of the NF-κB-DNA Interaction and Expression of NF-κB Upregulated Genes.

Synthesis and Pharmacological Evaluation of Dimeric Follicle-Stimulating Hormone Receptor Antagonists.

The Tertiary Amine Nitrogen Atom of Piperazine Sulfonamides as a Novel Determinant of Potent and Selective β<sub>3</sub>-Adrenoceptor Agonists.

[6,7]-Heterocycle-Fused 14-Hydroxymorphinan Derivatives: Design, Synthesis, and Opioid Receptor Activity.

2-Substituted-3-Dehydroquinic Acids as Potent Competitive Inhibitors of Type II Dehydroquinase.

Fast Prediction of Cytochrome P450 Mediated Drug Metabolism.

Preview: ChemMedChem 1/2010.

How to Replace the Residual Solvation Shell of Polar Active Site Residues to Achieve Nanomolar Inhibition of tRNA-Guanine Transglycosylase.

The Third Histamine Receptor. Edited by Divya Vohora.

Investigation of Trypanothione Reductase as a Drug Target in Trypanosoma brucei.

Aryldiketo Acids Have Antibacterial Activity Against MDR Staphylococcus aureus Strains: Structural Insights Based on Similarity and Molecular Interaction Fields.

Synthesis and Pharmacological Evaluation of SNC80 Analogues with a Bridged Piperazine Ring.

Graphical Abstract: ChemMedChem 12/2009.

Spotlights on our sister journals: ChemMedChem 12/2009.

Interaction of Artemisinins with Oxyhemoglobin Hb-Fe<sup>II</sup>, Hb-Fe<sup>II</sup>, CarboxyHb-Fe<sup>II</sup>, Heme-Fe<sup>II</sup>, and Carboxyheme Fe<sup>II</sup>: Significance for Mode of Action and Implications for Therapy of Cerebral Malaria.

Fluorine in Medicinal Chemistry and Chemical Biology. Edited by Iwao Ojima.

A Practical Total Synthesis of the Microbial Alkaline Proteinase Inhibitor (MAPI).

Thermodynamic Optimisation in Drug Discovery: A Case Study using Carbonic Anhydrase Inhibitors.

Inside Cover: Synthesis, Inhibition Potency, Binding Mode, and Antiprotozoal Activities of Fluorescent Inhibitors of Trypanothione Reductase Based on Mepacrine-Conjugated Diaryl Sulfide Scaffolds (ChemMedChem 12/2009).

Ring-Extended Derivatives of Gramicidin S with Furanoid Sugar Amino Acids in the Turn Region Have Enhanced Antimicrobial Activity.

Genomics in Drug Discovery and Development. By Dimitri Semizarov and Eric Blomme.

Cancer Chemotherapy: Basic Science to the Clinic. By Rachel Airley.

Fast Prediction of Cytochrome P450 Mediated Drug Metabolism.

Cover Picture: Interaction of Artemisinins with Oxyhemoglobin Hb-Fe<sup>II</sup>, Hb-Fe<sup>II</sup>, CarboxyHb-Fe<sup>II</sup>, Heme-Fe<sup>II</sup>, and Carboxyheme Fe<sup>II</sup>: Significance for Mode of Action and Implications for Therapy of Cerebral Malaria (ChemMedChem 12/2009)

Synthesis, Inhibition Potency, Binding Mode, and Antiprotozoal Activities of Fluorescent Inhibitors of Trypanothione Reductase Based on Mepacrine-Conjugated Diaryl Sulfide Scaffolds.

Azetidinones as Zinc-Binding Groups to Design Selective HDAC8 Inhibitors.