Works matching IS 18607179 AND DT 2009 AND VI 4 AND IP 10

Results: 28

Fragment-Based Drug Discovery: A Practical Approach. Edited by Edward R. Zartler and Michael J. Shapiro.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1756, doi. 10.1002/cmdc.200900251

By:

Rastelli, Giulio

Publication type:

Article

The Peptidylglycine α-Amidating Monooxygenase (PAM): A Novel Prodrug Strategy for Amidoximes and N-Hydroxyguanidines?

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1595, doi. 10.1002/cmdc.200900233

By:

Schade, Dennis;
Kotthaus, Joscha;
Hungeling, Helen;
Kotthaus, Jürke;
Clement, Bernd

Publication type:

Article

Inside Cover: Bioreductively Activated Lysyl Oxidase Inhibitors against Hypoxic Tumours (ChemMedChem 10/2009).

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1554, doi. 10.1002/cmdc.200990047

By:

Granchi, Carlotta;
Funaioli, Tiziana;
Erler, Janine T.;
Giaccia, Amato J.;
Macchia, Marco;
Minutolo, Filippo

Publication type:

Article

2,3-Dihydro-1-Benzofuran Derivatives as a Series of Potent Selective Cannabinoid Receptor 2 Agonists: Design, Synthesis, and Binding Mode Prediction through Ligand-Steered Modeling.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1615, doi. 10.1002/cmdc.200900226

By:

Diaz, Philippe;
Phatak, Sharangdhar S.;
Xu, Jijun;
Fronczek, Frank R.;
Astruc-Diaz, Fanny;
Thompson, Charles M.;
Cavasotto, Claudio N.;
Naguib, Mohamed

Publication type:

Article

Exploring Chemical Substructures Essential for hERG K+ Channel Blockade by Synthesis and Biological Evaluation of Dofetilide Analogues.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1722, doi. 10.1002/cmdc.200900203

By:

Shagufta;
Guo, Dong;
Klaasse, Elisabeth;
de Vries, Henk;
Brussee, Johannes;
Nalos, Lukáš;
Rook, Martin B.;
Vos, Marc A.;
van der Heyden, Marcel A. G.;
IJzerman, Adriaan P.

Publication type:

Article

Cover Picture: 2,3-Dihydro-1-Benzofuran Derivatives as a Series of Potent Selective Cannabinoid Receptor 2 Agonists: Design, Synthesis, and Binding Mode Prediction through Ligand-Steered Modeling (ChemMedChem 10/2009).

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1553, doi. 10.1002/cmdc.200990046

By:

Diaz, Philippe;
Phatak, Sharangdhar S.;
Xu, Jijun;
Fronczek, Frank R.;
Astruc-Diaz, Fanny;
Thompson, Charles M.;
Cavasotto, Claudio N.;
Naguib, Mohamed

Publication type:

Article

C3 Halogen and C8′′ Substituents on Stilbene Arotinoids Modulate Retinoic Acid Receptor Subtype Function.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1630, doi. 10.1002/cmdc.200900214

By:

Álvarez, Susana;
Khanwalkar, Harshal;
Álvarez, Rosana;
Erb, Cathie;
Martínez, Claudio;
Rodríguez-Barrios, Fátima;
Germain, Pierre;
Gronemeyer, Hinrich;
de Lera, Angel R.

Publication type:

Article

A Virtual Screening Study of the 18 kDa Translocator Protein using Pharmacophore Models Combined with 3D-QSAR Studies.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1686, doi. 10.1002/cmdc.200900254

By:

Tuccinardi, Tiziano;
Taliani, Sabrina;
Bellandi, Marusca;
Da Settimo, Federico;
Da Pozzo, Eleonora;
Martini, Claudia;
Martinelli, Adriano

Publication type:

Article

Structure-Based Design, Synthesis, and Evaluation of 2′-(2-Hydroxyethyl)-2′-deoxyadenosine and the 5′-Diphosphate Derivative as Ribonucleotide Reductase Inhibitors.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1649, doi. 10.1002/cmdc.200900236

By:

Sun, Dianqing;
Xu, Hai;
Wijerathna, Sanath R.;
Dealwis, Chris;
Lee, Richard E.

Publication type:

Article

Bioreductively Activated Lysyl Oxidase Inhibitors against Hypoxic Tumours.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1590, doi. 10.1002/cmdc.200900247

By:

Granchi, Carlotta;
Funaioli, Tiziana;
Erler, Janine T.;
Giaccia, Amato J.;
Macchia, Marco;
Minutolo, Filippo

Publication type:

Article

Optimization of Thienopyrrole-Based Finger-Loop Inhibitors of the Hepatitis C Virus NS5B Polymerase.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1695, doi. 10.1002/cmdc.200900184

By:

Martin Hernando, Jose Ignacio;
Ontoria, Jesus Maria;
Malancona, Savina;
Attenni, Barbara;
Fiore, Fabrizio;
Bonelli, Fabio;
Koch, Uwe;
Di Marco, Stefania;
Colarusso, Stefania;
Ponzi, Simona;
Gennari, Nadia;
Vignetti, Sue Ellen;
del Rosario Rico Ferreira, Maria;
Habermann, Jörg;
Rowley, Michael;
Narjes, Frank

Publication type:

Article

The Emerging Therapeutic Potential of Histone Methyltransferase and Demethylase Inhibitors.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1568, doi. 10.1002/cmdc.200900301

By:

Spannhoff, Astrid;
Hauser, Alexander-Thomas;
Heinke, Ralf;
Sippl, Wolfgang;
Jung, Manfred

Publication type:

Article

Design of Caspase Inhibitors as Potential Clinical Agents. Edited by Tom O'Brien and Steven D. Linton.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1758, doi. 10.1002/cmdc.200900305

By:

Pérez-Payá, Enrique

Publication type:

Article

Synthesis and Structure-Activity Relationships of Allosteric Potentiators of the M4 Muscarinic Acetylcholine Receptor.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1600, doi. 10.1002/cmdc.200900231

By:

Kennedy, J. Phillip;
Bridges, Thomas M.;
Gentry, Patrick R.;
Brogan, John T.;
Kane, Alexander S.;
Jones, Carrie K.;
Brady, Ashley E.;
Shirey, Jana K.;
Conn, P. Jeffrey;
Lindsley, Craig W.

Publication type:

Article

Bivalent Argininamide-Type Neuropeptide Y Y1 Antagonists Do Not Support the Hypothesis of Receptor Dimerisation.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1733, doi. 10.1002/cmdc.200900213

By:

Keller, Max;
Teng, Shangjun;
Bernhardt, Günther;
Buschauer, Armin

Publication type:

Article

The Relevance of Polar Surface Area (PSA) in Rationalizing Biological Properties of Several cis-Diamminemalonatoplatinum(II) Derivatives.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1677, doi. 10.1002/cmdc.200900224

By:

Caron, Giulia;
Ermondi, Giuseppe;
Gariboldi, Marzia B.;
Monti, Elena;
Gabano, Elisabetta;
Ravera, Mauro;
Osella, Domenico

Publication type:

Article

Spotlights on our sister journals: ChemMedChem 10/2009.

Published in:: ChemMedChem, 2009, v. 4, n. 10, p. 1564, doi. 10.1002/cmdc.200990049
Publication type:: Article

Manufacturing of Pharmaceutical Proteins: From Technology to Economy. By Stefan Behme.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1757, doi. 10.1002/cmdc.200900246

By:

Becker, Christian F. W.

Publication type:

Article

A Potent Activator of Melanogenesis Identified from Small-Molecule Screening.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1583, doi. 10.1002/cmdc.200900194

By:

McNaughton, Brian R.;
Gareiss, Peter C.;
Jacobs, Stacey E.;
Fricke, Alex F.;
Scott, Glynis A.;
Miller, Benjamin L.

Publication type:

Article

Antiparasitic and Antibacterial Drug Discovery. Edited by Paul M. Selzer.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1756, doi. 10.1002/cmdc.200900263

By:

Carter, Katharine

Publication type:

Article

Graphical Abstract: ChemMedChem 10/2009.

Published in:: ChemMedChem, 2009, v. 4, n. 10, p. 1555, doi. 10.1002/cmdc.200990048
Publication type:: Article

α-Bromoacrylamido N-Substituted Isatin Derivatives as Potent Inducers of Apoptosis in Human Myeloid Leukemia Cells.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1668, doi. 10.1002/cmdc.200900245

By:

Romagnoli, Romeo;
Baraldi, Pier Giovanni;
Cruz-Lopez, Olga;
Preti, Delia;
Bermejo, Jaime;
Estévez, Francisco

Publication type:

Article

Novel Antitumor L-Arabinose Derivative of Indolocarbazole with High Affinity to DNA.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1641, doi. 10.1002/cmdc.200900227

By:

Kaluzhny, Dmitry N.;
Tatarskiy, Victor V.;
Dezhenkova, Lyubov G.;
Plikhtyak, Irina L.;
Miniker, Tatyana D.;
Shchyolkina, Anna K.;
Strel'tsov, Sergey A.;
Chilov, Ghermes G.;
Novikov, Fedor N.;
Kubasova, Irina Yu.;
Smirnova, Zoya S.;
Mel'nik, Stalina Ya.;
Livshits, Mikhail A.;
Borisova, Olga F.;
Shtil, Alexander A.

Publication type:

Article

Aminocyclitol-Substituted Phytoceramides and their Effects on iNKT Cell Stimulation.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1608, doi. 10.1002/cmdc.200900193

By:

Harrak, Youssef;
Barra, Carolina M.;
Bedia, Carmen;
Delgado, Antonio;
Castaño, A. Raúl;
Llebaria, Amadeu

Publication type:

Article

Rapid Evaluation of Antrodia camphorata Natural Products and Derivatives in Tumourigenic Liver Progenitor Cells with a Novel Cell Proliferation Assay.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1657, doi. 10.1002/cmdc.200900238

By:

Stewart, Scott G.;
Ho, Louisa A.;
Polomska, Marta E.;
Percival, Alexander T.;
Yeoh, George C. T.

Publication type:

Article

Preview: ChemMedChem 11/2009.

Published in:: ChemMedChem, 2009, v. 4, n. 10, p. 1763, doi. 10.1002/cmdc.200990050
Publication type:: Article

N-(Anilinoethyl)amides: Design and Synthesis of Metabolically Stable, Selective Melatonin Receptor Ligands.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1746, doi. 10.1002/cmdc.200900240

By:

Rivara, Silvia;
Vacondio, Federica;
Fioni, Alessandro;
Silva, Claudia;
Carmi, Caterina;
Mor, Marco;
Lucini, Valeria;
Pannacci, Marilou;
Caronno, Alessia;
Scaglione, Francesco;
Gobbi, Gabriella;
Spadoni, Gilberto;
Bedini, Annalida;
Orlando, Pierfrancesco;
Lucarini, Simone;
Tarzia, Giorgio

Publication type:

Article

Design and Synthesis of a Series of Piperazine-1-carboxamidine Derivatives with Antifungal Activity Resulting from Accumulation of Endogenous Reactive Oxygen Species.

Published in:

ChemMedChem, 2009, v. 4, n. 10, p. 1714, doi. 10.1002/cmdc.200900249

By:

François, Isabelle E.;
Thevissen, Karin;
Pellens, Klaartje;
Meert, Els M.;
Heeres, Jan;
Freyne, Eddy;
Coesemans, Erwin;
Viellevoye, Marcel;
Deroose, Frederik;
Martinez Gonzalez, Sonia;
Pastor, Joaquin;
Corens, David;
Meerpoel, Lieven;
Borgers, Marcel;
Ausma, Jannie;
Dispersyn, Gerrit D.;
Cammue, Bruno P.

Publication type:

Article

Works matching IS 18607179 AND DT 2009 AND VI 4 AND IP 10

Fragment-Based Drug Discovery: A Practical Approach. Edited by Edward R. Zartler and Michael J. Shapiro.

The Peptidylglycine α-Amidating Monooxygenase (PAM): A Novel Prodrug Strategy for Amidoximes and N-Hydroxyguanidines?

Inside Cover: Bioreductively Activated Lysyl Oxidase Inhibitors against Hypoxic Tumours (ChemMedChem 10/2009).

2,3-Dihydro-1-Benzofuran Derivatives as a Series of Potent Selective Cannabinoid Receptor 2 Agonists: Design, Synthesis, and Binding Mode Prediction through Ligand-Steered Modeling.

Exploring Chemical Substructures Essential for hERG K<sup>+</sup> Channel Blockade by Synthesis and Biological Evaluation of Dofetilide Analogues.

Cover Picture: 2,3-Dihydro-1-Benzofuran Derivatives as a Series of Potent Selective Cannabinoid Receptor 2 Agonists: Design, Synthesis, and Binding Mode Prediction through Ligand-Steered Modeling (ChemMedChem 10/2009).

C3 Halogen and C8′′ Substituents on Stilbene Arotinoids Modulate Retinoic Acid Receptor Subtype Function.

A Virtual Screening Study of the 18 kDa Translocator Protein using Pharmacophore Models Combined with 3D-QSAR Studies.

Structure-Based Design, Synthesis, and Evaluation of 2′-(2-Hydroxyethyl)-2′-deoxyadenosine and the 5′-Diphosphate Derivative as Ribonucleotide Reductase Inhibitors.

Bioreductively Activated Lysyl Oxidase Inhibitors against Hypoxic Tumours.

Optimization of Thienopyrrole-Based Finger-Loop Inhibitors of the Hepatitis C Virus NS5B Polymerase.

The Emerging Therapeutic Potential of Histone Methyltransferase and Demethylase Inhibitors.

Design of Caspase Inhibitors as Potential Clinical Agents. Edited by Tom O'Brien and Steven D. Linton.

Synthesis and Structure-Activity Relationships of Allosteric Potentiators of the M<sub>4</sub> Muscarinic Acetylcholine Receptor.

Bivalent Argininamide-Type Neuropeptide Y Y<sub>1</sub> Antagonists Do Not Support the Hypothesis of Receptor Dimerisation.

The Relevance of Polar Surface Area (PSA) in Rationalizing Biological Properties of Several cis-Diamminemalonatoplatinum(II) Derivatives.

Spotlights on our sister journals: ChemMedChem 10/2009.

Manufacturing of Pharmaceutical Proteins: From Technology to Economy. By Stefan Behme.

A Potent Activator of Melanogenesis Identified from Small-Molecule Screening.

Antiparasitic and Antibacterial Drug Discovery. Edited by Paul M. Selzer.

Graphical Abstract: ChemMedChem 10/2009.

α-Bromoacrylamido N-Substituted Isatin Derivatives as Potent Inducers of Apoptosis in Human Myeloid Leukemia Cells.

Novel Antitumor L-Arabinose Derivative of Indolocarbazole with High Affinity to DNA.

Aminocyclitol-Substituted Phytoceramides and their Effects on iNKT Cell Stimulation.

Rapid Evaluation of Antrodia camphorata Natural Products and Derivatives in Tumourigenic Liver Progenitor Cells with a Novel Cell Proliferation Assay.

Preview: ChemMedChem 11/2009.

N-(Anilinoethyl)amides: Design and Synthesis of Metabolically Stable, Selective Melatonin Receptor Ligands.

Design and Synthesis of a Series of Piperazine-1-carboxamidine Derivatives with Antifungal Activity Resulting from Accumulation of Endogenous Reactive Oxygen Species.