Works matching IS 18607179 AND DT 2006 AND VI 1 AND IP 1

Results: 24

Click Chemistry on Azidoproline: High-Affinity Dual Antagonist for HIV-1 Envelope Glycoprotein gp120.

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 54, doi. 10.1002/cmdc.200500037

By:

Gopi, Hosahudya N.;
Tirupula, Kalyan C.;
Baxter, Sabine;
Ajith, Sandya;
Chaiken, Irwin M.

Publication type:

Article

Unexpected Novel Binding Mode of Pyrrolidine-Based Aspartyl Protease Inhibitors: Design, Synthesis and Crystal Structure in Complex with HIV Protease.

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 106, doi. 10.1002/cmdc.200500008

By:

Specker, Edgar;
Böttcher, Jark;
Brass, Sascha;
Heine, Andreas;
Lilie, Hauke;
Schoop, Andreas;
Müller, Gerhard;
Griebenow, Nils;
Klebe, Gerhard

Publication type:

Article

Preview: ChemMedChem 1/2006.

Published in:: ChemMedChem, 2006, v. 1, n. 1, p. 162, doi. 10.1002/cmdc.200690001
Publication type:: Article

Methods and Principles in Medicinal Chemistry 25: Microwaves in Organic and Medicinal Chemistry. By C. Oliver Kappe and Alexander Stadler.

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 158, doi. 10.1002/cmdc.200500050

By:

Strauss, Chris

Publication type:

Article

The Pipeline Is Filled...︁.

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 3, doi. 10.1002/cmdc.200500072

By:

Metternich, Rainer;
Tarzia, Giorgio;
Ronsisvalle, Guiseppe;
Stilz, Hans Ulrich

Publication type:

Article

2-{3-[2-(4-Chlorophenyl)ethoxy]phenylthio}-2-methylpropanoic Acid: a Fibrate-Like Compound with Hypolipidemic and Antidiabetic Activity.

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 49, doi. 10.1002/cmdc.200500007

By:

Dell'Uomo, Natalina;
Tassoni, Emanuela;
Brunetti, Tiziana;
Pessotto, Pompeo;
Sciarroni, Anna F.;
Milazzo, Ferdinando M.;
De Angelis, Francesco;
Peschechera, Alessandro;
Tinti, Maria O.;
Carminati, Paolo;
Giannessi, Fabio

Publication type:

Article

Cover Picture: Molecular Design and Chemical Synthesis of a Highly Potent Epothilone (ChemMedChem 1/2006).

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 1, doi. 10.1002/cmdc.200690000

By:

Nicolaou, K. C.;
Pratt, Benjamin A.;
Arseniyadis, Stellios;
Wartmann, Markus;
O'Brate, Aurora;
Giannakakou, Paraskevi

Publication type:

Article

Design, Synthesis, Biological Evaluation, and Molecular Modeling Studies of TIBO-Like Cyclic Sulfones as Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors.

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 82, doi. 10.1002/cmdc.200500020

By:

Di Santo, Roberto;
Costi, Roberta;
Artico, Marino;
Ragno, Rino;
Lavecchia, Antonio;
Novellino, Ettore;
Gavuzzo, Enrico;
La Torre, Francesco;
Cirilli, Roberto;
Cancio, Reynel;
Maga, Giovanni

Publication type:

Article

The Hit-to-Lead Process at Schering AG: Strategic Aspects.

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 31, doi. 10.1002/cmdc.200500031

By:

Steinmeyer, Andreas

Publication type:

Article

Effects of Conformational Dynamics on Predicted Protein Druggability.

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 70, doi. 10.1002/cmdc.200500013

By:

Brown, Scott P.;
Hajduk, Philip J.

Publication type:

Article

Biopolymers for Medical and Pharmaceutical Applications. Edited by Alexander Steinbüchel and Robert Marchessault.

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 159, doi. 10.1002/cmdc.200500053

By:

Sun, Xue-Long

Publication type:

Article

Prediction of Small-Molecule Binding to Cytochrome P450 3A4: Flexible Docking Combined with Multidimensional QSAR.

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 73, doi. 10.1002/cmdc.200500024

By:

Lill, Markus A.;
Dobler, Max;
Vedani, Angelo

Publication type:

Article

Synthesis and Structure-Activity Relationships of FAAH Inhibitors: Cyclohexylcarbamic Acid Biphenyl Esters with Chemical Modulation at the Proximal Phenyl Ring.

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 130, doi. 10.1002/cmdc.200500017

By:

Tarzia, Giorgio;
Duranti, Andrea;
Gatti, Giuseppe;
Piersanti, Giovanni;
Tontini, Andrea;
Rivara, Silvia;
Lodola, Alessio;
Plazzi, Pier Vincenzo;
Mor, Marco;
Kathuria, Satish;
Piomelli, Daniele

Publication type:

Article

An Albumin-Activated Far-Red Fluorochrome for In Vivo Imaging.

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 66, doi. 10.1002/cmdc.200500028

By:

Montet, Xavier;
Rajopadhye, Milind;
Weissleder, Ralph

Publication type:

Article

A Medicinal-Chemistry-Guided Approach to Selective and Druglike Sigma 1 Ligands.

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 140, doi. 10.1002/cmdc.200500034

By:

Corbera, Jordi;
Vaño, David;
Martínez, Daniel;
Vela, José M.;
Zamanillo, Daniel;
Dordal, Alberto;
Andreu, Francesc;
Hernandez, Enric;
Perez, Raquel;
Escriche, Marisol;
Salgado, Leonardo;
Yeste, Sandra;
Serafini, Maria Teresa;
Pascual, Rosalia;
Alegre, Júlia;
Calvet, Maria Carme;
Cano, Núria;
Carro, Mónica;
Buschmann, Helmut;
Holenz, Jörg

Publication type:

Article

Structural Remodeling of Cocaine: Design and Synthesis of Trisubstituted Cyclopropanes as Selective Serotonin Reuptake Inhibitors.

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 58, doi. 10.1002/cmdc.200500016

By:

Kozikowski, Alan P.;
Zhao, Lianyun;
Zhang, Ao;
Wang, Cheng Z.;
Flippen-Anderson, Judith;
Johnson, Kenneth M.

Publication type:

Article

Molecular Design and Chemical Synthesis of a Highly Potent Epothilone.

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 41, doi. 10.1002/cmdc.200500056

By:

Nicolaou, K. C.;
Pratt, Benjamin A.;
Arseniyadis, Stellios;
Wartmann, Markus;
O'Brate, Aurora;
Giannakakou, Paraskevi

Publication type:

Article

Selective Indole-Based ECE Inhibitors: Synthesis and Pharmacological Evaluation.

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 96, doi. 10.1002/cmdc.200500009

By:

Brands, Michael;
Ergüden, Jens-Kerim;
Hashimoto, Kentaro;
Heimbach, Dirk;
Krahn, Thomas;
Schröder, Christian;
Siegel, Stephan;
Stasch, Johannes-Peter;
Tsujishita, Hideki;
Weigand, Stefan;
Yoshida, Nagahiro H.

Publication type:

Article

European Medicinal Chemistry-Strategies, Targets, and Drugs under the Spotlight.

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 155, doi. 10.1002/cmdc.200500049

By:

Cramer, Jörg;
Berger, Michael

Publication type:

Article

Graphical Abstract: ChemMedChem 1/2006.

Published in:: ChemMedChem, 2006, v. 1, n. 1, p. 6, doi. 10.1002/cmdc.200690002
Publication type:: Article

Semisynthesis and Screening of a Small Library of Pro-Apoptotic Squamocin Analogues: Selection and Study of a Benzoquinone Hybrid with an Improved Biological Profile.

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 118, doi. 10.1002/cmdc.200500011

By:

Derbré, Séverine;
Duval, Romain;
Roué, Gaël;
Garofano, Aurelio;
Poupon, Erwan;
Brandt, Ulrich;
Susin, Santos A.;
Hocquemiller, Reynald

Publication type:

Article

Structure-Activity Relationships in Side-Chain-Modified Epothilone Analogues-How Important is the Position of the Nitrogen Atom?

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 37, doi. 10.1002/cmdc.200500051

By:

Bold, Guido;
Wojeik, Séverine;
Caravatti, Giorgio;
Lindauer, Renate;
Stierlin, Claire;
Gertsch, Jürg;
Wartmann, Markus;
Altmann, Karl-Heinz

Publication type:

Article

Aminothiazole Derivatives as Neuropeptide Y5 Receptor Ligands: Finding the Balance between Affinity and Physicochemical Properties.

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 45, doi. 10.1002/cmdc.200500022

By:

Nettekoven, Matthias;
Guba, Wolfgang;
Neidhart, Werner;
Mattei, Patrizio;
Pflieger, Philippe;
Plancher, Jean-Marc;
Taylor, Sven

Publication type:

Article

Current Developments in HIV Chemotherapy.

Published in:

ChemMedChem, 2006, v. 1, n. 1, p. 16, doi. 10.1002/cmdc.200500026

By:

Meadows, D. Christopher;
Gervay-Hague, Jacquelyn

Publication type:

Article