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Fast Prediction of Cytochrome P450 Mediated Drug Metabolism.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 1965, doi. 10.1002/cmdc.200990059
By:
- Rydberg, Patrik;
- Vasanthanathan, Poongavanam;
- Oostenbrink, Chris;
- Olsen, Lars
Publication type:
Article
Redox Signaling and Regulation in Biology and Medicine. Edited by Claus Jacob and Paul G. Winyard.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 2125, doi. 10.1002/cmdc.200900297
By:
- Krauth-Siegel, R. Luise
Publication type:
Article
Modelling Atypical Small-Molecule Mimics of an Important Stem Cell Cytokine, Thrombopoietin.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 2002, doi. 10.1002/cmdc.200900340
By:
- Tarasova, Anna;
- Winkler, David A.
Publication type:
Article
Virtual Screening against p50 NF-κB Transcription Factor for the Identification of Inhibitors of the NF-κB-DNA Interaction and Expression of NF-κB Upregulated Genes.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 2024, doi. 10.1002/cmdc.200900362
By:
- Piccagli, Laura;
- Fabbri, Enrica;
- Borgatti, Monica;
- Bianchi, Nicoletta;
- Bezzerri, Valentino;
- Mancini, Irene;
- Nicolis, Elena;
- Dechecchi, Cristina M.;
- Lampronti, Ilaria;
- Cabrini, Giulio;
- Gambari, Roberto
Publication type:
Article
Synthesis and Pharmacological Evaluation of Dimeric Follicle-Stimulating Hormone Receptor Antagonists.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 2098, doi. 10.1002/cmdc.200900344
By:
- Bonger, Kimberly M.;
- Hoogendoorn, Sascha;
- van Koppen, Chris J.;
- Timmers, Cornelis M.;
- Overkleeft, Herman S.;
- van der Marel, Gijsbert A.
Publication type:
Article
The Tertiary Amine Nitrogen Atom of Piperazine Sulfonamides as a Novel Determinant of Potent and Selective β3-Adrenoceptor Agonists.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 2080, doi. 10.1002/cmdc.200900292
By:
- Perrone, Maria Grazia;
- Bleve, Laura;
- Santandrea, Ernesto;
- Vitale, Paola;
- Niso, Mauro;
- Scilimati, Antonio
Publication type:
Article
[6,7]-Heterocycle-Fused 14-Hydroxymorphinan Derivatives: Design, Synthesis, and Opioid Receptor Activity.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 2103, doi. 10.1002/cmdc.200900308
By:
- Li, Fuying;
- Yin, Chenlei;
- Chen, Jie;
- Liu, Jinggen;
- Xie, Xin;
- Zhang, Ao
Publication type:
Article
2-Substituted-3-Dehydroquinic Acids as Potent Competitive Inhibitors of Type II Dehydroquinase.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 1980, doi. 10.1002/cmdc.200900319
By:
- Prazeres, Verónica F. V.;
- Castedo, Luis;
- Lamb, Heather;
- Hawkins, Alastair R.;
- González-Bello, Concepción
Publication type:
Article
Preview: ChemMedChem 1/2010.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 2135, doi. 10.1002/cmdc.200990061
Publication type:
Article
How to Replace the Residual Solvation Shell of Polar Active Site Residues to Achieve Nanomolar Inhibition of tRNA-Guanine Transglycosylase.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 2012, doi. 10.1002/cmdc.200900343
By:
- Ritschel, Tina;
- Kohler, Philipp C.;
- Neudert, Gerd;
- Heine, Andreas;
- Diederich, François;
- Klebe, Gerhard
Publication type:
Article
The Third Histamine Receptor. Edited by Divya Vohora.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 2126, doi. 10.1002/cmdc.200900428
By:
- Provins, Laurent
Publication type:
Article
Investigation of Trypanothione Reductase as a Drug Target in Trypanosoma brucei.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 2060, doi. 10.1002/cmdc.200900262
By:
- Spinks, Daniel;
- Shanks, Emma J.;
- Cleghorn, Laura A. T.;
- McElroy, Stuart;
- Jones, Deuan;
- James, Daniel;
- Fairlamb, Alan H.;
- Frearson, Julie A.;
- Wyatt, Paul G.;
- Gilbert, Ian H.
Publication type:
Article
Aryldiketo Acids Have Antibacterial Activity Against MDR Staphylococcus aureus Strains: Structural Insights Based on Similarity and Molecular Interaction Fields.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 1971, doi. 10.1002/cmdc.200900273
By:
- Drakulić, Branko J.;
- Stavri, Michael;
- Gibbons, Simon;
- Žižak, Željko S.;
- Verbić, Tatjana Ž.;
- Juranić, Ivan O.;
- Zloh, Mire
Publication type:
Article
Synthesis and Pharmacological Evaluation of SNC80 Analogues with a Bridged Piperazine Ring.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 2111, doi. 10.1002/cmdc.200900358
By:
- Holl, Ralph;
- Jung, Bettina;
- Schepmann, Dirk;
- Humpf, Hans-Ulrich;
- Grünert, Renate;
- Bednarski, Patrick J.;
- Englberger, Werner;
- Wünsch, Bernhard
Publication type:
Article
Graphical Abstract: ChemMedChem 12/2009.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 1959, doi. 10.1002/cmdc.200990058
Publication type:
Article
Spotlights on our sister journals: ChemMedChem 12/2009.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 1968, doi. 10.1002/cmdc.200990060
Publication type:
Article
Interaction of Artemisinins with Oxyhemoglobin Hb-FeII, Hb-FeII, CarboxyHb-FeII, Heme-FeII, and Carboxyheme FeII: Significance for Mode of Action and Implications for Therapy of Cerebral Malaria.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 2045, doi. 10.1002/cmdc.200900342
By:
- Coghi, Paolo;
- Basilico, Nicoletta;
- Taramelli, Donatella;
- Chan, Wing-Chi;
- Haynes, Richard K.;
- Monti, Diego
Publication type:
Article
Fluorine in Medicinal Chemistry and Chemical Biology. Edited by Iwao Ojima.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 2124, doi. 10.1002/cmdc.200900306
By:
- Fustero, Santos
Publication type:
Article
A Practical Total Synthesis of the Microbial Alkaline Proteinase Inhibitor (MAPI).
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 2054, doi. 10.1002/cmdc.200900346
By:
- Haebich, Dieter;
- Hillisch, Alexander;
- El Sheikh, Sherif
Publication type:
Article
Thermodynamic Optimisation in Drug Discovery: A Case Study using Carbonic Anhydrase Inhibitors.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 1985, doi. 10.1002/cmdc.200900386
By:
- Scott, Andrew D.;
- Phillips, Chris;
- Alex, Alexander;
- Flocco, Maria;
- Bent, Andrew;
- Randall, Amy;
- O'Brien, Ronan;
- Damian, Luminita;
- Jones, Lyn H.
Publication type:
Article
Inside Cover: Synthesis, Inhibition Potency, Binding Mode, and Antiprotozoal Activities of Fluorescent Inhibitors of Trypanothione Reductase Based on Mepacrine-Conjugated Diaryl Sulfide Scaffolds (ChemMedChem 12/2009).
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 1958, doi. 10.1002/cmdc.200990057
By:
- Eberle, Christian;
- Burkhard, Johannes A.;
- Stump, Bernhard;
- Kaiser, Marcel;
- Brun, Reto;
- Krauth-Siegel, R. Luise;
- Diederich, François
Publication type:
Article
Ring-Extended Derivatives of Gramicidin S with Furanoid Sugar Amino Acids in the Turn Region Have Enhanced Antimicrobial Activity.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 1976, doi. 10.1002/cmdc.200900379
By:
- Knijnenburg, Annemiek D.;
- Spalburg, Emile;
- de Neeling, Albert J.;
- Mars-Groenendijk, Roos H.;
- Noort, Daan;
- Grotenbreg, Gijsbert M.;
- van der Marel, Gijsbert A.;
- Overkleeft, Herman S.;
- Overhand, Mark
Publication type:
Article
Genomics in Drug Discovery and Development. By Dimitri Semizarov and Eric Blomme.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 2126, doi. 10.1002/cmdc.200900400
By:
- Knapp, Stefan
Publication type:
Article
Cancer Chemotherapy: Basic Science to the Clinic. By Rachel Airley.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 2123, doi. 10.1002/cmdc.200900323
By:
- Altmann, Karl-Heinz
Publication type:
Article
Fast Prediction of Cytochrome P450 Mediated Drug Metabolism.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 2070, doi. 10.1002/cmdc.200900363
By:
- Rydberg, Patrik;
- Vasanthanathan, Poongavanam;
- Oostenbrink, Chris;
- Olsen, Lars
Publication type:
Article
Cover Picture: Interaction of Artemisinins with Oxyhemoglobin Hb-FeII, Hb-FeII, CarboxyHb-FeII, Heme-FeII, and Carboxyheme FeII: Significance for Mode of Action and Implications for Therapy of Cerebral Malaria (ChemMedChem 12/2009)
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 1957, doi. 10.1002/cmdc.200990056
By:
- Coghi, Paolo;
- Basilico, Nicoletta;
- Taramelli, Donatella;
- Chan, Wing-Chi;
- Haynes, Richard K.;
- Monti, Diego
Publication type:
Article
Synthesis, Inhibition Potency, Binding Mode, and Antiprotozoal Activities of Fluorescent Inhibitors of Trypanothione Reductase Based on Mepacrine-Conjugated Diaryl Sulfide Scaffolds.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 2034, doi. 10.1002/cmdc.200900327
By:
- Eberle, Christian;
- Burkhard, Johannes A.;
- Stump, Bernhard;
- Kaiser, Marcel;
- Brun, Reto;
- Krauth-Siegel, R. Luise;
- Diederich, François
Publication type:
Article
Azetidinones as Zinc-Binding Groups to Design Selective HDAC8 Inhibitors.
Published in:
ChemMedChem, 2009, v. 4, n. 12, p. 1991, doi. 10.1002/cmdc.200900309
By:
- Galletti, Paola;
- Quintavalla, Arianna;
- Ventrici, Caterina;
- Giannini, Giuseppe;
- Cabri, Walter;
- Penco, Sergio;
- Gallo, Grazia;
- Vincenti, Silvia;
- Giacomini, Daria
Publication type:
Article

Found: 28

Fast Prediction of Cytochrome P450 Mediated Drug Metabolism.

Redox Signaling and Regulation in Biology and Medicine. Edited by Claus Jacob and Paul G. Winyard.

Modelling Atypical Small-Molecule Mimics of an Important Stem Cell Cytokine, Thrombopoietin.

Virtual Screening against p50 NF-κB Transcription Factor for the Identification of Inhibitors of the NF-κB-DNA Interaction and Expression of NF-κB Upregulated Genes.

Synthesis and Pharmacological Evaluation of Dimeric Follicle-Stimulating Hormone Receptor Antagonists.

The Tertiary Amine Nitrogen Atom of Piperazine Sulfonamides as a Novel Determinant of Potent and Selective β<sub>3</sub>-Adrenoceptor Agonists.

[6,7]-Heterocycle-Fused 14-Hydroxymorphinan Derivatives: Design, Synthesis, and Opioid Receptor Activity.

2-Substituted-3-Dehydroquinic Acids as Potent Competitive Inhibitors of Type II Dehydroquinase.

Preview: ChemMedChem 1/2010.

How to Replace the Residual Solvation Shell of Polar Active Site Residues to Achieve Nanomolar Inhibition of tRNA-Guanine Transglycosylase.

The Third Histamine Receptor. Edited by Divya Vohora.

Investigation of Trypanothione Reductase as a Drug Target in Trypanosoma brucei.

Aryldiketo Acids Have Antibacterial Activity Against MDR Staphylococcus aureus Strains: Structural Insights Based on Similarity and Molecular Interaction Fields.

Synthesis and Pharmacological Evaluation of SNC80 Analogues with a Bridged Piperazine Ring.

Graphical Abstract: ChemMedChem 12/2009.

Spotlights on our sister journals: ChemMedChem 12/2009.

Interaction of Artemisinins with Oxyhemoglobin Hb-Fe<sup>II</sup>, Hb-Fe<sup>II</sup>, CarboxyHb-Fe<sup>II</sup>, Heme-Fe<sup>II</sup>, and Carboxyheme Fe<sup>II</sup>: Significance for Mode of Action and Implications for Therapy of Cerebral Malaria.

Fluorine in Medicinal Chemistry and Chemical Biology. Edited by Iwao Ojima.

A Practical Total Synthesis of the Microbial Alkaline Proteinase Inhibitor (MAPI).

Thermodynamic Optimisation in Drug Discovery: A Case Study using Carbonic Anhydrase Inhibitors.

Inside Cover: Synthesis, Inhibition Potency, Binding Mode, and Antiprotozoal Activities of Fluorescent Inhibitors of Trypanothione Reductase Based on Mepacrine-Conjugated Diaryl Sulfide Scaffolds (ChemMedChem 12/2009).

Ring-Extended Derivatives of Gramicidin S with Furanoid Sugar Amino Acids in the Turn Region Have Enhanced Antimicrobial Activity.

Genomics in Drug Discovery and Development. By Dimitri Semizarov and Eric Blomme.

Cancer Chemotherapy: Basic Science to the Clinic. By Rachel Airley.

Fast Prediction of Cytochrome P450 Mediated Drug Metabolism.

Cover Picture: Interaction of Artemisinins with Oxyhemoglobin Hb-Fe<sup>II</sup>, Hb-Fe<sup>II</sup>, CarboxyHb-Fe<sup>II</sup>, Heme-Fe<sup>II</sup>, and Carboxyheme Fe<sup>II</sup>: Significance for Mode of Action and Implications for Therapy of Cerebral Malaria (ChemMedChem 12/2009)

Synthesis, Inhibition Potency, Binding Mode, and Antiprotozoal Activities of Fluorescent Inhibitors of Trypanothione Reductase Based on Mepacrine-Conjugated Diaryl Sulfide Scaffolds.

Azetidinones as Zinc-Binding Groups to Design Selective HDAC8 Inhibitors.