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Results: 32

Exosomes in atherosclerosis: performers, bystanders, biomarkers, and therapeutic targets.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3996, doi. 10.7150/thno.56035
By:
- Chen Wang;
- Zhelong Li;
- Yunnan Liu;
- Lijun Yuan
Publication type:
Article
SIRT3-mediated deacetylation of NLRC4 promotes inflammasome activation.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3981, doi. 10.7150/thno.55573
By:
- Chenyang Guan;
- Xian Huang;
- Jinnan Yue;
- Hongrui Xiang;
- Samina Shaheen;
- Zhenyan Jiang;
- Yuexiao Tao;
- Jun Tu;
- Zhenshan Liu;
- Yufeng Yao;
- Wen Yang;
- Zhaoyuan Hou;
- Junling Liu;
- Xiao-Dong Yang;
- Qiang Zou;
- Bing Su;
- Zhiduo Liu;
- Jun Ni;
- Jinke Cheng;
- Xuefeng Wu
Publication type:
Article
Downregulation of death receptor 4 is tightly associated with positive response of EGFR mutant lung cancer to EGFR-targeted therapy and improved prognosis.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3964, doi. 10.7150/thno.54824
By:
- Shuo Zhang;
- Zhen Chen;
- Puyu Shi;
- Songqing Fan;
- Yong He;
- Qiming Wang;
- Yixiang Li;
- Ramalingam, Suresh S.;
- Owonikoko, Taofeek K.;
- Shi-Yong Sun
Publication type:
Article
Overcoming erlotinib resistance in EGFR mutation-positive lung adenocarcinomas through repression of phosphoglycerate dehydrogenase: Erratum.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3963, doi. 10.7150/thno.58558
Publication type:
Article
LncRNA PFL contributes to cardiac fibrosis by acting as a competing endogenous RNA of let-7d: Erratum.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3961, doi. 10.7150/thno.58328
Publication type:
Article
Injectable conductive hydrogel can reduce pacing threshold and enhance efficacy of cardiac pacemaker.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3948, doi. 10.7150/thno.54959
By:
- Zhao An;
- Jun Wu;
- Shu-Hong Li;
- Shanglin Chen;
- Fang-Lin Lu;
- Zhi-Yun Xu;
- Hsing-Wen Sung;
- Ren-Ke Li
Publication type:
Article
Exosomal miR-500a-5p derived from cancer-associated fibroblasts promotes breast cancer cell proliferation and metastasis through targeting USP28.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3932, doi. 10.7150/thno.53412
By:
- Bing Chen;
- Yuting Sang;
- Xiaojin Song;
- Dong Zhang;
- Lijuan Wang;
- Wenjing Zhao;
- Yiran Liang;
- Ning Zhang;
- Qifeng Yang
Publication type:
Article
Engineering extracellular vesicles with platelet membranes fusion enhanced targeted therapeutic angiogenesis in a mouse model of myocardial ischemia reperfusion.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3916, doi. 10.7150/thno.52496
By:
- Qiyu Li;
- Yanan Song;
- Qiaozi Wang;
- Jing Chen;
- Jinfeng Gao;
- Haipeng Tan;
- Su Li;
- Yuan Wu;
- Hongbo Yang;
- Hanwei Huang;
- Yang Yu;
- Yao Li;
- Ning Zhang;
- Zheyong Huang;
- Zhiqing Pang;
- Juying Qian;
- Junbo Ge
Publication type:
Article
The short isoform of PRLR suppresses the pentose phosphate pathway and nucleotide synthesis through the NEK9-Hippo axis in pancreatic cancer.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3898, doi. 10.7150/thno.51712
By:
- Huizhen Nie;
- Pei-Qi Huang;
- Shu-Heng Jiang;
- Qin Yang;
- Li-Peng Hu;
- Xiao-Mei Yang;
- Jun Li;
- Ya-Hui Wang;
- Qing Li;
- Yi-Fan Zhang;
- Lei Zhu;
- Yan-Li Zhang;
- Yanqiu Yu;
- Xiao, Gary Guishan;
- Yong-Wei Sun;
- Jianguang Ji;
- Zhi-Gang Zhang
Publication type:
Article
Molecular targets for anticancer therapies in companion animals and humans: what can we learn from each other?
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3882, doi. 10.7150/thno.55760
By:
- Hernández, Irati Beltrán;
- Kromhout, Jannes Z.;
- Teske, Erik;
- Hennink, Wim E.;
- van Nimwegen, Sebastiaan A.;
- Oliveira, Sabrina
Publication type:
Article
KDM6B-mediated histone demethylation of LDHA promotes lung metastasis of osteosarcoma.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3868, doi. 10.7150/thno.53347
By:
- Yuhang Jiang;
- Fengfeng Li;
- Bowen Gao;
- Mengjun Ma;
- Meng Chen;
- Yanfeng Wu;
- Weidong Zhang;
- Yangbai Sun;
- Sanhong Liu;
- Huiyong Shen
Publication type:
Article
MERS-CoV and SARS-CoV-2 replication can be inhibited by targeting the interaction between the viral spike protein and the nucleocapsid protein.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3853, doi. 10.7150/thno.55647
By:
- Byoung Kwon Park;
- Jinsoo Kim;
- Sangkyu Park;
- Dongbum Kim;
- Minyoung Kim;
- Kyeongbin Baek;
- Joon-Yong Bae;
- Man-Seong Park;
- Won-Keun Kim;
- Younghee Lee;
- Hyung-Joo Kwon
Publication type:
Article
Lactate-induced M2 polarization of tumor-associated macrophages promotes the invasion of pituitary adenoma by secreting CCL17.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3839, doi. 10.7150/thno.53749
By:
- Anke Zhang;
- Yuanzhi Xu;
- Houshi Xu;
- Jie Ren;
- Tong Meng;
- Yunjia Ni;
- Qingwei Zhu;
- Wen-Bo Zhang;
- Yuan-Bo Pan;
- Jiali Jin;
- Yunke Bi;
- Zhe Bao Wu;
- Shaojian Lin;
- Meiqing Lou
Publication type:
Article
Sunitinib-induced cardiac hypertrophy and the endothelin axis.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3830, doi. 10.7150/thno.49837
By:
- Sourdon, Joevin;
- Facchin, Caterina;
- Certain, Anaïs;
- Viel, Thomas;
- Robin, Blaise;
- Lager, Franck;
- Marchiol, Carmen;
- Balvay, Daniel;
- Yoganathan, Thulaciga;
- Favier, Judith;
- Tharaux, Pierre-Louis;
- Dhaun, Neeraj;
- Renault, Gilles;
- Tavitian, Bertrand
Publication type:
Article
Paraventricular thalamic nucleus plays a critical role in consolation and anxious behaviors of familiar observers exposed to surgery mice.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3813, doi. 10.7150/thno.45690
By:
- Qiuting Zeng;
- Weiran Shan;
- Hui Zhang;
- Jianjun Yang;
- Zhiyi Zuo
Publication type:
Article
Impairment of type H vessels by NOX2-mediated endothelial oxidative stress: critical mechanisms and therapeutic targets for bone fragility in streptozotocin-induced type 1 diabetic mice.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3796, doi. 10.7150/thno.50907
By:
- Xiao-Fan Hu;
- Geng Xiang;
- Tian-Ji Wang;
- Yu-Bo Ma;
- Yang Zhang;
- Ya-Bo Yan;
- Xiong Zhao;
- Zi-Xiang Wu;
- Ya-Fei Feng;
- Wei Lei
Publication type:
Article
Granzyme A inhibition reduces inflammation and increases survival during abdominal sepsis.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3781, doi. 10.7150/thno.49288
By:
- Garzón-Tituaña, Marcela;
- Sierra-Monzón, José L.;
- Comas, Laura;
- Santiago, Llipsy;
- Khaliulina-Ushakova, Tatiana;
- Uranga-Murillo, Iratxe;
- Ramirez-Labrada, Ariel;
- Tapia, Elena;
- Morte-Romea, Elena;
- Algarate, Sonia;
- Couty, Ludovic;
- Camerer, Eric;
- Bird, Phillip I.;
- Seral, Cristina;
- Luque, Pilar;
- Paño-Pardo, José R.;
- Galvez, Eva M.;
- Pardo, Julián;
- Arias, Maykel
Publication type:
Article
Environmental enrichment implies GAT-1 as a potential therapeutic target for stroke recovery.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3760, doi. 10.7150/thno.53316
By:
- Yuhui Lin;
- Mengcheng Yao;
- Haiyin Wu;
- Feng Wu;
- Shiying Cao;
- Huanyu Ni;
- Jian Dong;
- Di Yang;
- Yanyu Sun;
- Xiaolin Kou;
- Jun Li;
- Hui Xiao;
- Lei Chang;
- Jin Wu;
- Yan Liu;
- Chunxia Luo;
- Dongya Zhu
Publication type:
Article
PRMT5 functionally associates with EZH2 to promote colorectal cancer progression through epigenetically repressing CDKN2B expression.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3742, doi. 10.7150/thno.53023
By:
- Liu Yang;
- Da-wei Ma;
- Yue-peng Cao;
- Dong-zheng Li;
- Xin Zhou;
- Ji-feng Feng;
- Jun Bao
Publication type:
Article
Dual-ligand supramolecular nanofibers inspired by the renin-angiotensin system for the targeting and synergistic therapy of myocardial infarction.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3725, doi. 10.7150/thno.53644
By:
- Zhanpeng Wen;
- Jie Zhan;
- Hekai Li;
- Guanghui Xu;
- Shaodan Ma;
- Jianwu Zhang;
- Zehua Li;
- Caiwen Ou;
- Zhimou Yang;
- Yanbin Cai;
- Minsheng Chen
Publication type:
Article
Biocompatible AIEgen/p-glycoprotein siRNA@reductionsensitive paclitaxel polymeric prodrug nanoparticles for overcoming chemotherapy resistance in ovarian cancer.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3710, doi. 10.7150/thno.53828
By:
- Jun Wu;
- Quan Wang;
- Xiaoqi Dong;
- Min Xu;
- Juliang Yang;
- Xiaoqing Yi;
- Biao Chen;
- Xiyuan Dong;
- Ying Wang;
- Xiaoding Lou;
- Fan Xia;
- Shixuan Wang;
- Jun Dai
Publication type:
Article
Polysaccharide mycophenolate-based nanoparticles for enhanced immunosuppression and treatment of immune-mediated inflammatory diseases.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3694, doi. 10.7150/thno.52891
By:
- Yuce Li;
- Yuchen Lou;
- Yu Chen;
- Jing Yang;
- Danqi Li;
- Biling Jiang;
- Jiajia Lan;
- Jingjing Wen;
- Yangxue Fu;
- Yamin Zhang;
- Juan Tao;
- Jintao Zhu
Publication type:
Article
Downregulated METTL14 accumulates BPTF that reinforces super-enhancers and distal lung metastasis via glycolytic reprogramming in renal cell carcinoma.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3676, doi. 10.7150/thno.55424
By:
- Chuanjie Zhang;
- Li Chen;
- Yihan Liu;
- Jingyi Huang;
- Ao Liu;
- Yang Xu;
- Yan Shen;
- Hongchao He;
- Danfeng Xu
Publication type:
Article
Identification of theranostic factors for patients developing metastasis after surgery for early-stage lung adenocarcinoma.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3661, doi. 10.7150/thno.53176
By:
- Wei-Chung Cheng;
- Chun-Yu Chang;
- Chia-Chien Lo;
- Chih-Ying Hsieh;
- Ting-Ting Kuo;
- Guan-Chin Tseng;
- Sze-Ching Wong;
- Shu-Fen Chiang;
- Chih-Yang Huang, Kevin;
- Liang-Chuan Lai;
- Tzu-Pin Lu;
- Chao, K. S. Clifford;
- Yuh-Pyng Sher
Publication type:
Article
Nanodefensin-encased hydrogel with dual bactericidal and pro-regenerative functions for advanced wound therapy.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3642, doi. 10.7150/thno.53089
By:
- Gan Luo;
- Yaqi Sun;
- Jue Zhang;
- Zhipeng Xu;
- Wuyuan Lu;
- Hanbin Wang;
- Yan Zhang;
- Hui Li;
- Zhengwei Mao;
- Shixin Ye;
- Baoli Cheng;
- Xiangming Fang
Publication type:
Article
Genome-wide CRISPR/Cas9 knockout screening uncovers a novel inflammatory pathway critical for resistance to arginine-deprivation therapy.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3624, doi. 10.7150/thno.51795
By:
- Cheng-Ying Chu;
- Yi-Ching Lee;
- Cheng-Han Hsieh;
- Chi-Tai Yeh;
- Tsu-Yi Chao;
- Po-Hung Chen;
- I-Hsuan Lin;
- Tsung-Han Hsieh;
- Jing-Wen Shih;
- Chia-Hsiung Cheng;
- Che-Chang Chang;
- Ping-Sheng Lin;
- Yuan-Li Huang;
- Tsung-Ming Chen;
- Yun Yen;
- Ann, David K.;
- Hsing-Jien Kung
Publication type:
Article
MiR-22 modulates brown adipocyte thermogenesis by synergistically activating the glycolytic and mTORC1 signaling pathways.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3607, doi. 10.7150/thno.50900
By:
- Pengbo Lou;
- Xueyun Bi;
- Yuhua Tian;
- Guilin Li;
- Qianqian Kang;
- Cong Lv;
- Yongli Song;
- Jiuzhi Xu;
- Xiaole Sheng;
- Xu Yang;
- Ruiqi Liu;
- Qingyong Meng;
- Fazheng Ren;
- Plikus, Maksim V.;
- Bin Liang;
- Bing Zhang;
- Huiyuan Guo;
- Zhengquan Yu
Publication type:
Article
Vitamin C activates pyruvate dehydrogenase (PDH) targeting the mitochondrial tricarboxylic acid (TCA) cycle in hypoxic KRAS mutant colon cancer.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3595, doi. 10.7150/thno.51265
By:
- Cenigaonandia-Campillo, Aiora;
- Serna-Blasco, Roberto;
- Gómez-Ocabo, Laura;
- Solanes-Casado, Sonia;
- Baños-Herraiz, Natalia;
- Del Puerto-Nevado, Laura;
- Antonio Cañas, Jose;
- Jesús Aceñero, María;
- García-Foncillas, Jesús;
- Aguilera, Óscar
Publication type:
Article
Calcium phosphate engineered photosynthetic microalgae to combat hypoxic-tumor by in-situ modulating hypoxia and cascade radio-phototherapy.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3580, doi. 10.7150/thno.55441
By:
- Danni Zhong;
- Wanlin Li;
- Shiyuan Hua;
- Yuchen Qi;
- Tingting Xie;
- Yue Qiao;
- Min Zhou
Publication type:
Article
The immune contexture of primary central nervous system diffuse large B cell lymphoma associates with patient survival and specific cell signaling.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3565, doi. 10.7150/thno.54343
By:
- Alame, Melissa;
- Cornillot, Emmanuel;
- Cacheux, Valère;
- Rigau, Valérie;
- Costes-Martineau, Valérie;
- Lacheretz-Szablewski, Vanessa;
- Colinge, Jacques
Publication type:
Article
Vitamin C sensitizes triple negative breast cancer to PI3K inhibition therapy.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3552, doi. 10.7150/thno.53225
By:
- Mustafi, Sushmita;
- Camarena, Vladimir;
- Qureshi, Rehana;
- Sant, David W.;
- Wilkes, Zachary;
- Bilbao, Daniel;
- Slingerland, Joyce;
- Kesmodel, Susan B.;
- Wang, Gaofeng
Publication type:
Article
Aldehyde dehydrogenase inhibitors promote DNA damage in ovarian cancer and synergize with ATM/ATR inhibitors.
Published in:
Theranostics, 2021, v. 11, n. 8, p. 3540, doi. 10.7150/thno.51885
By:
- Grimley, Edward;
- Cole, Alexander J.;
- Luong, Thong T.;
- McGonigal, Stacy C.;
- Sinno, Sarah;
- Dongli Yang;
- Bernstein, Kara A.;
- Buckanovich, Ronald J.
Publication type:
Article