Works in Theranostics, 2025, Vol 15, Issue 15

Results: 30

Targeting granulosa cells with engineered DFO nanoparticles for the treatment of chemotherapy-induced premature ovarian failure.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7820, doi. 10.7150/thno.115416

By:

Tuo Zhang;
Zhiyi Sheng;
Jixian Zhang;
Heng Zhang;
Yan Zhang;
Yunpeng Du;
Xiangxin Liu;
Zhu Hu;
Qiyuan Luo;
Guoqiang Xu;
Yuan Gao;
Meina He;
Tengxiang Chen

Publication type:

Article

Engineered RAP-anchored copper-escorting liposomes for FDX1-targeted cuproptosis in glioblastoma therapy.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7802, doi. 10.7150/thno.115723

By:

Meng-Meng Liu;
Ling-Xiao Zhao;
Zhi-Qiang Gong;
Yi-Jiang He;
Xue Jiang;
Wei Luo;
Xin Yu;
Zhan-You Wang

Publication type:

Article

Harnessing mRNA for heart health: a new era in cardiovascular treatment.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7779, doi. 10.7150/thno.111503

By:

Fengli Peng;
Zhimei Qiu;
Zimu Wang;
Fuhai Li;
Fating Zhou;
Shuai Yuan;
Jinsong Yuan;
Yan Wang;
Yongchao Zhao;
Chaofu Li;
Bei Shi

Publication type:

Article

Smart Nanoarchitectures for Precision RNA Delivery: Harnessing Endogenous and Exogenous Stimuli in Cancer Treatment.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7747, doi. 10.7150/thno.112492

By:

Jintao Hao;
Yue Li;
Lu Huang;
Nannan Qi;
Yanan Sun;
Chaoxing He;
Shaokun Yang;
Zhiyun Niu;
Xianrong Qi;
Bai Xiang

Publication type:

Article

Tetrahydromagnolol induces autophagic cell death by targeting the m6 A reader protein YTHDF2 and enhances the efficacy of anti-PD-1 immunotherapy in pancreatic cancer cells.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7726, doi. 10.7150/thno.112612

By:

Guohua Li;
Qibiao Wu;
Yiping Mou;
Yunhao Qiao;
Lijun Jin;
Qian Shi;
Ruonan Zhang;
Jie Li;
Yitian Sun;
Aili Zhang;
Haiyang Jiang;
Zijing Yang;
Zhiyu Zhu;
Mengmeng Ma;
Xiaoyu Sun;
Xinbing Sui

Publication type:

Article

Tumor Exosomal HIF2A Induce Peritumoral M2 Macrophages Accumulation to Facilitate Intestinal Invasion in Colorectal Cancer.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7709, doi. 10.7150/thno.113190

By:

Dan Wang;
Qingyang Lei;
Li Yang;
Yachang Huo;
Weina Yu;
Shasha Liu;
Yangfei Duan;
Shumin Feng;
Zhen Li;
Jinbo Liu;
Zhenqiang Sun;
Weitang Yuan;
Lihua Liu;
Bin Zhang;
Yi Zhang

Publication type:

Article

Gut microbiota-derived formate exacerbates pulmonary metastasis in cancer.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7693, doi. 10.7150/thno.108873

By:

Prajnamitra, Ray Putra;
Chaw Yee Beh;
Wen-Hung Tang;
Shu-Chian Ruan;
Yuan-Yuan Cheng;
Pei-Teng Kuo;
Yu-Wen Tien;
Ching-Ho Hsieh, Patrick

Publication type:

Article

NIR-II light-driven in situ nanovaccine for cancer immunotherapy via lymph node migration-mediated accumulation.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7677, doi. 10.7150/thno.114347

By:

Yucheng Huang;
Miao Su;
Weihuan Lin;
Peirong Zhang;
Hengliang Hou;
Fanjun Zeng;
Luyu Huang;
Qiaxuan Li;
Jialong Deng;
Shengbo Liu;
Hongrui Qiu;
Xiaoqing Yuan;
Li Peng;
Bin Xu;
Haiyu Zhou

Publication type:

Article

Multi-dimensional data-driven computational drug repurposing strategy for screening novel neuroprotective agents in ischemic stroke.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7653, doi. 10.7150/thno.112608

By:

Qingqi Meng;
Qing Liu;
Yan Mi;
Libin Xu;
Feng Wang;
Danyang Mu;
Yueyang Liu;
Yuxin Yang;
Yongye Huang;
Dakuo He;
Yue Hou

Publication type:

Article

Phase-specific and laser-modulated polydopamine-chlorella-curdlan hydrogels: pioneering a melanoma integrative therapy.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7627, doi. 10.7150/thno.113417

By:

Zhenzhen Yan;
Tinglin Zhang;
Yuxiang Wang;
Chao Ji;
Heru Wang;
Yicheng Ma;
Jingzhu Li;
Yixin Wu;
Zhi Liu;
Jingnan Xun;
Xiaowan Fang;
Yongjun Zheng;
Shizhao Ji;
Shichu Xiao;
Jie Gao

Publication type:

Article

Metabolic Targeting of Oxidative Phosphorylation Enhances Chemosensitivity in Triple-Negative Breast Cancer via a Synergistic Nanomedicine.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7607, doi. 10.7150/thno.116250

By:

Xiaoding Shen;
Hao Cai;
Yihan Wang;
Maodi Xie;
Yunkun Li;
Dayi Pan;
Jing Jing;
Qiyong Gong;
Kui Luo

Publication type:

Article

Extracellular vesicle-mediated spinal cord-brain crosstalk induces hippocampal neurogenesis impairment and cognitive deficits post-spinal cord injury.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7584, doi. 10.7150/thno.110560

By:

Tian Qin;
Yiming Qin;
Yuxin Jin;
Xiangyu Liang;
Yi Sun;
Baozhi Liu;
Hongbin Lu;
Chengjun Li;
Jianzhong Hu;
Liyuan Jiang

Publication type:

Article

Calcium dysregulation disrupts mitochondrial homeostasis by interfering AMPK/Drp1 pathway to aggravate plaque progression and instability.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7567, doi. 10.7150/thno.112041

By:

Pingping Hu;
Mengmeng Liu;
Tongtong Wu;
Yiping Zhang;
Chenyuan Liu;
Langtao Wang;
Wanping Zhang;
Yumei Que;
Jiali You;
Weimin Yu;
Xiaoyong Tong

Publication type:

Article

Lung cancer diagnosis through extracellular vesicle analysis using label-free surface-enhanced Raman spectroscopy coupled with machine learning.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7545, doi. 10.7150/thno.110178

By:

Hai-Sha Liu;
Kai-Wen Ye;
Jun Liu;
Jin-Kuang Jiang;
Ying-Fang Jian;
Dong-Mei Chen;
Chao Kang;
Li Qiu;
Ya-Juan Liu

Publication type:

Article

The LRP4/YAP axis drives the radiation-tolerant persister (RTP) cell state in breast cancer.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7528, doi. 10.7150/thno.101393

By:

Forissier, Violaine;
Wicinski, Julien;
Castagné, Martin;
Pinna, Guillaume;
Shuheng Lin;
Grandon, Anaïs;
Bonnet, Caroline;
Macario, Manon;
Castellano, Remy;
Valdenaire, Simon;
Darréon, Julien;
Tallet, Agnès;
Ginestier, Christophe;
Charafe-Jauffret, Emmanuelle

Publication type:

Article

Secreted Clever-1 modulates T cell responses and impacts cancer immunotherapy efficacy.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7501, doi. 10.7150/thno.110544

By:

Prince, Stuart;
Viitala, Miro;
Sjöroos, Riikka;
Bendes, Ábris Á.;
Rannikko, Jenna H.;
Patten, Daniel A.;
di Benedetto, Ilaria;
Turpin, Rita;
Ylitalo, Arno;
Tyni, Laura;
Figueiredo, Carlos R.;
Boström, Pia;
Koskivuo, Ilkka;
Salminen, Tiina A.;
Shetty, Shishir;
Hollmén, Maija

Publication type:

Article

Comparison of targeting two antigens (GPA33 versus HER2) for 225Ac-pretargeted alpha-radioimmunotherapy of colorectal cancer.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7489, doi. 10.7150/thno.116062

By:

Rinne, Sara S.;
Vargas, Daniela Burnes;
Vaughn, Brett A.;
Katugampola, Sumudu;
Miller, Brian W.;
Veach, Darren R.;
Punzalan, Blesida;
de Stanchina, Elisa;
Yaeger, Rona;
Miranda, Ileana C.;
Hong Xu;
Hongfen Guo;
Schwartz, Jazmin;
Fung, Edward K.;
Howell, Roger W.;
Larson, Steven M.;
Cheung, Nai-Kong V.;
Cheal, Sarah M.

Publication type:

Article

Mn3O4 nanozyme-based anti-inflammatory therapy modulates microglial phenotype by downregulating TLR4/NOX2 expression and further alleviates Alzheimer's disease pathology.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7467, doi. 10.7150/thno.112213

By:

Jun Xie;
Kai Cao;
Luman Liu;
Liding Zhang;
Ying Yang;
Hui Gong;
Haiming Luo

Publication type:

Article

GD2-mediated impairment of macrophage phagocytosis drives pulmonary metastasis in osteosarcoma.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7454, doi. 10.7150/thno.113887

By:

Yunfei He;
Peng Yang;
Peng Ding;
Zeng Zhang;
Jichuan Wu;
Chunjie Wang;
Guanghui Hou;
Jun Ge;
Quan Zhou;
Zhuorun Song;
Huilin Yang;
Tao Liu;
Shunyi Lu

Publication type:

Article

AI-powered 3D pathology protocol enhances enteric nervous system visualization and quantification for clinical diagnostics.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7440, doi. 10.7150/thno.112024

By:

Young Hyun Yun;
Kee Young Chung;
Yunjoo Lee;
Tae Sik Sung;
Dayoung Ko;
Seung-Bum Ryoo;
Hyun-Young Kim;
Kyu Joo Park;
Jong Pil Im;
Byeong Gwan Kim;
Joo Sung Kim;
Seong-Joon Koh;
Hyung Jin Choi

Publication type:

Article

A strain-programmed lignin-based Janus patch for rapid healing of postoperative rectal wounds.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7425, doi. 10.7150/thno.115444

By:

Yi Yu;
Jiaxin Pan;
Jianbo Zhang;
Zhengdong Zhang;
Chenghao Qiu;
Yiming Xiang;
Yizhou Zhu;
Zhanjun Wu;
Peng Yu;
Tong Li;
Lei Tan

Publication type:

Article

Unraveling α-synuclein and amylin co-aggregation: pathological insights and biomarker development for Parkinson’s disease.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7409, doi. 10.7150/thno.112396

By:

Yuhang Zhou;
Minchao Lai;
Bowen Shu;
Benguo Wang;
Dian Wang;
Haoran Liu;
Baowan Li;
Jianhe Guo;
Dongjie Hu;
Mingyuan Li;
Cheng Zhu;
Muzhi Kang;
Zhong Alan Li;
Renzhi Wang;
Yongjuan Zhao;
Tuan, Rocky S.;
Keying Guo;
Chenzhong Li;
Cheng Jiang

Publication type:

Article

Focusing on the interplay between tumor-associated macrophages and tumor microenvironment: from mechanism to intervention.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7378, doi. 10.7150/thno.113727

By:

Hancheng Wu;
Jing Li;
Ruilin Yao;
Jing Liu;
Lili Su;
Wenjie You

Publication type:

Article

Artemisiae Annuae Herba: from anti-malarial legacy to emerging anti-cancer potential.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7346, doi. 10.7150/thno.115414

By:

Jing Sun;
Junzi Xufeng;
Zejing Qiu;
Quan Gao;
Zhiyu Zhu;
Jun He;
Shegan Gao;
Xinbing Sui

Publication type:

Article

Neutrophil extracellular traps aggravate neuronal apoptosis and neuroinflammation via neddylation after traumatic brain injury.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7327, doi. 10.7150/thno.111512

By:

Xu Zhang;
Jianye Xu;
Yonggang Fan;
Guihong Shi;
Bo Chen;
Wang, Anni;
Yanlin Zhu;
Lei Li;
Haoran Jia;
Gheyret, Dilmurat;
Jinchao Wang;
Yiyao Cao;
Shenghui Li;
Xin Chen;
Jianning Zhang;
Shu Zhang

Publication type:

Article

Disrupted macrophage metabolic adaptation and function drive senescence-induced decline in vertebrate regeneration.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7308, doi. 10.7150/thno.111352

By:

Barthelaix, Audrey;
Terraza-Aguirre, Claudia;
Río-Jay, Yalén Del;
Bohaud, Candice;
Salvador, Jérémy;
Morille, Marie;
Ferreira, Miguel Godinho;
Jorgensen, Christian;
Djouad, Farida

Publication type:

Article

Tea plant-inspired nanoassembled supraparticles alleviate colitis and associated mental disorders via microbiota-gut-brain interactions.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7291, doi. 10.7150/thno.113573

By:

Qinling Liu;
Yunxiang He;
Qingxin Fan;
Yue Wu;
Jiawen Li;
Siqi Deng;
Qiuping Xie;
Yueling Zhao;
Junling Guo;
Xiao Du

Publication type:

Article

Liver-targeted degradation of BRD4 reverses hepatic fibrosis and enhances metabolism in murine models.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7270, doi. 10.7150/thno.113852

By:

Shengjie Yuan;
Ayesha Nisar;
Chuanjie Chen;
Xin Dong;
Yongzhang Pan;
Meiting Zi;
Qiong Wang;
Sawar Khan;
Yaxun Guo;
Xuan Zhang;
Yonghan He

Publication type:

Article

Single-cell RNA sequencing uncovers intestinal immune alterations and cellular diversity from chronic fluoride exposure in mice.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7242, doi. 10.7150/thno.116567

By:

Jinge Xin;
Yu Chen;
Yongmei Huang;
Ning Sun;
Weiqi Peng;
Chunxiao Lai;
Ruanruan Yang;
Wenqing Chen;
Lixiao Duan;
Dandan Wang;
Yuhao He;
Yang Bai;
Xueqin Ni;
Hesong Wang

Publication type:

Article

Phosphoserine aminotransferase 1 promotes serine synthesis pathway and cardiac repair after myocardial infarction.

Published in:

Theranostics, 2025, v. 15, n. 15, p. 7219, doi. 10.7150/thno.112077

By:

Magadum, Ajit;
Mallaredy, Vandana;
Roy, Rajika;
Joladarashi, Darukeshwara;
Thej, Charan;
Zhongjian Cheng;
Cimini, Maria;
Truongcao, May;
Chatoff, Adam;
Crispim, Claudia V.;
Rigaud, Vagner O. C.;
Gonzalez, Carolina;
Benedict, Cindy;
Santos, Celio X. C.;
Snyder, Nathaniel W.;
Khan, Mohsin;
Shah, Ajay M.;
Koch, Walter J.;
Kishore, Raj

Publication type:

Article

Works in Theranostics, 2025, Vol 15, Issue 15

Targeting granulosa cells with engineered DFO nanoparticles for the treatment of chemotherapy-induced premature ovarian failure.

Engineered RAP-anchored copper-escorting liposomes for FDX1-targeted cuproptosis in glioblastoma therapy.

Harnessing mRNA for heart health: a new era in cardiovascular treatment.

Smart Nanoarchitectures for Precision RNA Delivery: Harnessing Endogenous and Exogenous Stimuli in Cancer Treatment.

Tetrahydromagnolol induces autophagic cell death by targeting the m<sup>6</sup> A reader protein YTHDF2 and enhances the efficacy of anti-PD-1 immunotherapy in pancreatic cancer cells.

Tumor Exosomal HIF2A Induce Peritumoral M2 Macrophages Accumulation to Facilitate Intestinal Invasion in Colorectal Cancer.

Gut microbiota-derived formate exacerbates pulmonary metastasis in cancer.

NIR-II light-driven in situ nanovaccine for cancer immunotherapy via lymph node migration-mediated accumulation.

Multi-dimensional data-driven computational drug repurposing strategy for screening novel neuroprotective agents in ischemic stroke.

Phase-specific and laser-modulated polydopamine-chlorella-curdlan hydrogels: pioneering a melanoma integrative therapy.

Metabolic Targeting of Oxidative Phosphorylation Enhances Chemosensitivity in Triple-Negative Breast Cancer via a Synergistic Nanomedicine.

Extracellular vesicle-mediated spinal cord-brain crosstalk induces hippocampal neurogenesis impairment and cognitive deficits post-spinal cord injury.

Calcium dysregulation disrupts mitochondrial homeostasis by interfering AMPK/Drp1 pathway to aggravate plaque progression and instability.

Lung cancer diagnosis through extracellular vesicle analysis using label-free surface-enhanced Raman spectroscopy coupled with machine learning.

The LRP4/YAP axis drives the radiation-tolerant persister (RTP) cell state in breast cancer.

Secreted Clever-1 modulates T cell responses and impacts cancer immunotherapy efficacy.

Comparison of targeting two antigens (GPA33 versus HER2) for <sup>225</sup>Ac-pretargeted alpha-radioimmunotherapy of colorectal cancer.

Mn<sub>3</sub>O<sub>4</sub> nanozyme-based anti-inflammatory therapy modulates microglial phenotype by downregulating TLR4/NOX2 expression and further alleviates Alzheimer's disease pathology.

GD2-mediated impairment of macrophage phagocytosis drives pulmonary metastasis in osteosarcoma.

AI-powered 3D pathology protocol enhances enteric nervous system visualization and quantification for clinical diagnostics.

A strain-programmed lignin-based Janus patch for rapid healing of postoperative rectal wounds.

Unraveling α-synuclein and amylin co-aggregation: pathological insights and biomarker development for Parkinson’s disease.

Focusing on the interplay between tumor-associated macrophages and tumor microenvironment: from mechanism to intervention.

Artemisiae Annuae Herba: from anti-malarial legacy to emerging anti-cancer potential.

Neutrophil extracellular traps aggravate neuronal apoptosis and neuroinflammation via neddylation after traumatic brain injury.

Disrupted macrophage metabolic adaptation and function drive senescence-induced decline in vertebrate regeneration.

Tea plant-inspired nanoassembled supraparticles alleviate colitis and associated mental disorders via microbiota-gut-brain interactions.

Liver-targeted degradation of BRD4 reverses hepatic fibrosis and enhances metabolism in murine models.

Single-cell RNA sequencing uncovers intestinal immune alterations and cellular diversity from chronic fluoride exposure in mice.

Phosphoserine aminotransferase 1 promotes serine synthesis pathway and cardiac repair after myocardial infarction.