Works in Molecular Medicine Reports, 2019, Vol 20, Issue 4

Results: 107

Microarray analysis of the molecular mechanisms associated with age and body mass index in human meniscal injury.

Published in:

2019

By:

Huang, Peiyan;
Gu, Jun;
Wu, Junguo;
Geng, Lei;
Hong, Yang;
Wang, Siqun;
Wang, Minghai

Publication type:

Correction Notice

miR-497 inhibits the proliferation and migration of A549 non-small-cell lung cancer cells by targeting FGFR1.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3959, doi. 10.3892/mmr.2019.10611

By:

Huang, Qibin;
Li, Hongtao;
Dai, Xiaofeng;
Zhao, Di;
Guan, Bingfeng;
Xia, Wen

Publication type:

Article

Polygonatum sibiricum polysaccharide alleviates inflammatory cytokines and promotes glucose uptake in high-glucose- and high-insulin-induced 3T3-L1 adipocytes by promoting Nrf2 expression.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3951, doi. 10.3892/mmr.2019.10626

By:

Cai, Jialuo;
Zhu, Yilin;
Zuo, Yajie;
Tong, Qiaozhen;
Zhang, Zhiguo;
Yang, Lei;
Li, Xiaoping;
Yi, Gangqiang

Publication type:

Article

Intracarotid cold saline infusion contributes to neuroprotection in MCAO-induced ischemic stroke in rats via serum and glucocorticoid-regulated kinase 1.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3942, doi. 10.3892/mmr.2019.10599

By:

Wang, Dazhi;
Huang, Zhi;
Li, Lei;
Yuan, Yingnan;
Xiang, Lei;
Wu, Xiaowen;
Ni, Caifang;
Yu, Wenfeng

Publication type:

Article

Yeast extract inhibits the proliferation of renal cell carcinoma cells via regulation of iron metabolism.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3933, doi. 10.3892/mmr.2019.10593

By:

Moon, Daeun;
Kim, Jinu;
Yoon, Sang-Pil

Publication type:

Article

Effects of vascular endothelial growth factor and insulin growth factor-1 on proliferation, migration, osteogenesis and vascularization of human carious dental pulp stem cells.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3924, doi. 10.3892/mmr.2019.10606

By:

Lu, Wanyu;
Xu, Wenan;
Li, Jianjia;
Chen, Yan;
Pan, Yuhua;
Wu, Buling

Publication type:

Article

Increased lncRNA HOTAIR expression promotes the chemoresistance of multiple myeloma to dexamethasone by regulating cell viability and apoptosis by mediating the JAK2/STAT3 signaling pathway.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3917, doi. 10.3892/mmr.2019.10603

By:

Guan, Rongyan;
Wang, Wei;
Fu, Bin;
Pang, Yujun;
Lou, Ye;
Li, Hong

Publication type:

Article

Willed-movement training reduces middle cerebral artery occlusion-induced motor deficits and improves angiogenesis and survival of cerebral endothelial cells via upregulating hypoxia-inducible factor-1α.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3910, doi. 10.3892/mmr.2019.10578

By:

Zhou, Zhiwen;
Ren, Xiang;
Zhou, Wensheng;
Zheng, Lijun

Publication type:

Article

miR-519d-3p promotes TGFβ/Smad mediated postoperative epidural scar formation via suppression of BAMBI.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3901, doi. 10.3892/mmr.2019.10630

By:

Yang, Longbiao;
Gao, Qingyuan;
Lv, Feng;
Guo, Min;
Zhao, Dong

Publication type:

Article

Silencing of CD86 in dendritic cells by small interfering RNA regulates cytokine production in T cells from patients with allergic rhinitis in vitro.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3893, doi. 10.3892/mmr.2019.10638

By:

Sun, Rong;
Yang, Yang;
Gu, Zheng;
Tang, Xinye;
Zhang, Cheng;
Kou, Wei;
Wei, Ping

Publication type:

Article

Hydroxychloroquine reverses the drug resistance of leukemic K562/ADM cells by inhibiting autophagy.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3883, doi. 10.3892/mmr.2019.10621

By:

Wang, Feifei;
Zhang, Zhewen;
Leung, Wing Ting;
Chen, Jing;
Yi, Juan;
Ying, Chunmei;
Yuan, Minmin;
Wang, Mingyan;
Zhang, Na;
Qiu, Xuemin;
Wang, Ling;
Wei, Hulai

Publication type:

Article

MicroRNA-373 exerts anti-tumor functions in human liver cancer by targeting Rab22a.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3874, doi. 10.3892/mmr.2019.10600

By:

Ye, Ying;
Zhang, Lijun;
Song, Yanan;
Zhuang, Juhua;
Wang, Guoyu;
Ni, Jing;
Zhang, Suiliang;
Xia, Wei

Publication type:

Article

lncRNA-NR024118 overexpression reverses LPS-induced inflammatory injury and apoptosis via NF-κB/Nrf2 signaling in ATDC5 chondrocytes.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3867, doi. 10.3892/mmr.2019.10639

By:

Mei, Xiaoliang;
Tong, Jian;
Zhu, Wei;
Zhu, Yongliang

Publication type:

Article

Identification of key miRNA-mRNA pairs in septic mice by bioinformatics analysis.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3858, doi. 10.3892/mmr.2019.10594

By:

Chen, Jianxin;
Lin, Min;
Zhang, Sen

Publication type:

Article

Upregulation of lncRNA RMRP promotes the activation of cardiac fibroblasts by regulating miR-613.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3849, doi. 10.3892/mmr.2019.10634

By:

Zhang, Shuang-Yin;
Huang, Sheng-Hui;
Gao, Shi-Xiong;
Wang, Ying-Bin;
Jin, Ping;
Lu, Feng-Jiao

Publication type:

Article

p27kip1 haploinsufficiency preserves myocardial function in the early stages of myocardial infarction via Atg5-mediated autophagy flux restoration.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3840, doi. 10.3892/mmr.2019.10632

By:

Zhou, Ningtian;
Huang, Qiong;
Cheng, Weili;
Ge, Yingbin;
Li, Dianfu;
Wang, Junhong

Publication type:

Article

Effect of astragaloside IV and the role of nuclear receptor RXRα in human peritoneal mesothelial cells in high glucose-based peritoneal dialysis fluids.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3829, doi. 10.3892/mmr.2019.10604

By:

Zhu, Weiwei;
Zhang, Xin;
Gao, Kun;
Wang, Xufang

Publication type:

Article

hNTCP-expressing primary pig hepatocytes are a valuable tool for investigating hepatitis B virus infection and antiviral drugs.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3820, doi. 10.3892/mmr.2019.10628

By:

Zhou, Ming;
Qin, Bo;
Deng, Xue-Song;
Zeng, Xiao-Li;
Lu, Ying;
Huang, Zi-Gang;
Wu, Chun-Chen;
Mou, Li-Sha

Publication type:

Article

COX-2 promotes epithelial-mesenchymal transition and migration in osteosarcoma MG-63 cells via PI3K/AKT/NF-κB signaling.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3811, doi. 10.3892/mmr.2019.10598

By:

Zhang, Xueliang;
Qu, Peng;
Zhao, Hui;
Zhao, Tong;
Cao, Nong

Publication type:

Article

Glycylglycine plays critical roles in the proliferation of spermatogonial stem cells.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3802, doi. 10.3892/mmr.2019.10609

By:

Xu, Bo;
Wei, Xiang;
Chen, Minjian;
Xie, Kaipeng;
Zhang, Yuqing;
Huang, Zhenyao;
Dong, Tianyu;
Hu, Weiyue;
Zhou, Kun;
Han, Xiumei;
Wu, Xin;
Xia, Yankai

Publication type:

Article

Overexpression of PTEN may increase the effect of pemetrexed on A549 cells via inhibition of the PI3K/AKT/mTOR pathway and carbohydrate metabolism.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3793, doi. 10.3892/mmr.2019.10617

By:

Li, Bo;
Zhang, Junkai;
Su, Ya;
Hou, Yiling;
Wang, Zhenguo;
Zhao, Lin;
Sun, Shengkai;
Fu, Hao

Publication type:

Article

lncRNA ROR promotes the progression of renal cell carcinoma through the miR-206/VEGF axis.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3782, doi. 10.3892/mmr.2019.10636

By:

Shi, Jianguo;
Zhang, Datian;
Zhong, Zhenhai;
Zhang, Wen

Publication type:

Article

Expression of TIGIT/CD155 and correlations with clinical pathological features in human hepatocellular carcinoma.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3773, doi. 10.3892/mmr.2019.10641

By:

Duan, Xiangguo;
Liu, Juanxi;
Cui, Jianjian;
Ma, Bin;
Zhou, Qiunan;
Yang, Xiaojuan;
Lu, Zhenhui;
Du, Yong;
Su, Chunxia

Publication type:

Article

Proteinase-activated receptor 2 deficiency is a protective factor against cardiomyocyte apoptosis during myocardial ischemia/reperfusion injury.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3764, doi. 10.3892/mmr.2019.10618

By:

Wang, Min;
Ma, Yiwen;
Zhang, Tiantian;
Gao, Lin;
Zhang, Shan;
Chen, Qizhi

Publication type:

Article

MicroRNA-301a-3p overexpression promotes cell invasion and proliferation by targeting runt-related transcription factor 3 in prostate cancer.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3755, doi. 10.3892/mmr.2019.10650

By:

Fan, Li;
Wang, Yao;
Huo, Wei;
Wang, Wei-Hua

Publication type:

Article

miR-488 negatively regulates osteogenic differentiation of bone marrow mesenchymal stem cells induced by psoralen by targeting Runx2.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3746, doi. 10.3892/mmr.2019.10613

By:

Huang, Yongquan;
Hou, Qiuke;
Su, Haitao;
Chen, Dongfeng;
Luo, Yiwen;
Jiang, Tao

Publication type:

Article

Silencing Smad4 attenuates sensitivity of colorectal cancer cells to cetuximab by promoting epithelial-mesenchymal transition.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3735, doi. 10.3892/mmr.2019.10597

By:

Lin, Zhenlv;
Zhang, Lin;
Zhou, Junfeng;
Zheng, Jiantao

Publication type:

Article

Sam68 mediates high glucose-induced podocyte apoptosis through modulation of Bax/Bcl-2.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3728, doi. 10.3892/mmr.2019.10601

By:

Chen, Yuyu;
Zhang, Li;
Liu, Shuangxin;
Yao, Binfeng;
Zhang, Hong;
Liang, Shun;
Ma, Jianchao;
Liang, Xinling;
Shi, Wei

Publication type:

Article

Accumulation of advanced glycation end products potentiate human retinal capillary endothelial cells mediated diabetic retinopathy.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3719, doi. 10.3892/mmr.2019.10590

By:

Tao, Dan;
Ni, Ninghua;
Zhang, Tiesong;
Li, Chao;
Sun, Qing;
Wang, Ling;
Mei, Yan

Publication type:

Article

Piperine ameliorates the severity of fibrosis via inhibition of TGF-β/SMAD signaling in a mouse model of chronic pancreatitis.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3709, doi. 10.3892/mmr.2019.10635

By:

Choi, Ji-Won;
Lee, Sung-Kon;
Kim, Myoung-Jin;
Kim, Dong-Gu;
Shin, Joon-Yeon;
Zhou, Ziqi;
Jo, Il-Joo;
Song, Ho-Joon;
Bae, Gi-Sang;
Park, Sung-Joo

Publication type:

Article

Discovery of potent telomerase activators: Unfolding new therapeutic and anti-aging perspectives.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3701, doi. 10.3892/mmr.2019.10614

By:

Tsoukalas, Dimitris;
Fragkiadaki, Persefoni;
Docea, Anca Oana;
Alegakis, Athanasios K.;
Sarandi, Evangelia;
Thanasoula, Maria;
Spandidos, Demetrios A.;
Tsatsakis, Aristidis;
Razgonova, Mayya Petrovna;
Calina, Daniela

Publication type:

Article

Methylophiopogonanone B of Radix Ophiopogonis protects cells from H2O2-induced apoptosis through the NADPH oxidase pathway in HUVECs.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3691, doi. 10.3892/mmr.2019.10625

By:

Wang, Liling;
Zhou, Yifeng;
Qin, Yuchuan;
Wang, Yanbin;
Liu, Bentong;
Fang, Ru;
Bai, Minge

Publication type:

Article

Screening of key genes associated with R-CHOP immunochemotherapy and construction of a prognostic risk model in diffuse large B-cell lymphoma.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3679, doi. 10.3892/mmr.2019.10627

By:

Liu, Ran;
Chen, Zhi;
Wang, Shujun;
Zhao, Gang;
Gu, Yan;
Han, Qi;
Chen, Baoan

Publication type:

Article

Filamin A regulates EGFR/ERK/Akt signaling and affects colorectal cancer cell growth and migration.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3671, doi. 10.3892/mmr.2019.10622

By:

Wang, Kun;
Zhu, Tie-Nian;
Zhao, Rui-Jing

Publication type:

Article

CENPO expression regulates gastric cancer cell proliferation and is associated with poor patient prognosis.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3661, doi. 10.3892/mmr.2019.10624

By:

Cao, Yi;
Xiong, Jianbo;
Li, Zhengrong;
Zhang, Guoyang;
Tu, Yi;
Wang, Lizhen;
Jie, Zhigang

Publication type:

Article

Integrative genomics analysis of hub genes and their relationship with prognosis and signaling pathways in esophageal squamous cell carcinoma.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3649, doi. 10.3892/mmr.2019.10608

By:

Chen, Fang-Fang;
Zhang, Shi-Rong;
Peng, Hao;
Chen, Yun-Zhao;
Cui, Xiao-Bin

Publication type:

Article

CFHR1 is a potentially downregulated gene in lung adenocarcinoma.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3642, doi. 10.3892/mmr.2019.10644

By:

Wu, Geting;
Yan, Yuanliang;
Wang, Xiang;
Ren, Xinxin;
Chen, Xi;
Zeng, Shuangshuang;
Wei, Jie;
Qian, Long;
Yang, Xue;
Ou, Chunlin;
Lin, Wei;
Gong, Zhicheng;
Zhou, Jianhua;
Xu, Zhijie

Publication type:

Article

MicroRNA-212 facilitates the motility and invasiveness of esophageal squamous carcinoma cells.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3633, doi. 10.3892/mmr.2019.10647

By:

Chen, Zhi;
Liu, Yuzhen;
Qi, Bo;
Gu, Chengwei;
Wei, Xiufeng;
Guo, Ling;
Yao, Wenjian;
Zhao, Baosheng

Publication type:

Article

Synergistic effect of STAT3-targeted small interfering RNA and AZD0530 against glioblastoma in vitro and in vivo.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3625, doi. 10.3892/mmr.2019.10596

By:

Liu, Qingjun;
Wang, Leibo;
Li, David;
Zhao, Jingxia;
Chen, Shen;
Li, Jialin

Publication type:

Article

MicroRNA-155 inhibits the proliferation of CD8+ T cells via upregulating regulatory T cells in vitiligo.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3617, doi. 10.3892/mmr.2019.10607

By:

Lv, Mingfen;
Li, Zhengjun;
Liu, Jingjing;
Lin, Fan;
Zhang, Qianwen;
Li, Zhiming;
Wang, Yi;
Wang, Keyu;
Xu, Yunsheng

Publication type:

Article

DNA-PKcs PARylation regulates DNA-PK kinase activity in the DNA damage response.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3609, doi. 10.3892/mmr.2019.10640

By:

Han, Yang;
Jin, Feng;
Xie, Ying;
Liu, Yike;
Hu, Sai;
Liu, Xiao-Dan;
Guan, Hua;
Gu, Yongqing;
Ma, Teng;
Zhou, Ping-Kun

Publication type:

Article

Clofarabine-phytochemical combination exposures in CML cells inhibit DNA methylation machinery, upregulate tumor suppressor genes and promote caspase-dependent apoptosis.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3597, doi. 10.3892/mmr.2019.10619

By:

Kaufman-Szymczyk, Agnieszka;
Majda, Katarzyna;
Szuławska-Mroczek, Agata;
Fabianowska-Majewska, Krystyna;
Lubecka, Katarzyna

Publication type:

Article

The identification of CRNDE, H19, UCA1 and HOTAIR as the key lncRNAs involved in oxaliplatin or irinotecan resistance in the chemotherapy of colorectal cancer based on integrative bioinformatics analysis.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3583, doi. 10.3892/mmr.2019.10588

By:

Sun, Fangfang;
Liang, Weiwei;
Qian, Jing

Publication type:

Article

Microtubule-severing protein Katanin p60 ATPase-containing subunit A-like 1 is involved in pole-based spindle organization during mouse oocyte meiosis.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3573, doi. 10.3892/mmr.2019.10605

By:

Gao, Lei-Lei;
Xu, Fei;
Jin, Zhen;
Ying, Xiao-Yan;
Liu, Jin-Wei

Publication type:

Article

Expression and function of Toll-like receptors in peripheral blood mononuclear cells in patients with ankylosing spondylitis.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3565, doi. 10.3892/mmr.2019.10631

By:

Zhang, Jun;
Xu, Rongming;
Wu, Lei;
Jiang, Jihong

Publication type:

Article

Strontium-containing α-calcium sulfate hemihydrate promotes bone repair via the TGF-β/Smad signaling pathway.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3555, doi. 10.3892/mmr.2019.10592

By:

Liu, Zhi;
Yu, Zewei;
Chang, Hong;
Wang, Yu;
Xiang, Haibo;
Zhang, Xianrong;
Yu, Bin

Publication type:

Article

Crosstalk between microRNAs, the putative target genes and the lncRNA network in metabolic diseases.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3543, doi. 10.3892/mmr.2019.10595

By:

Assmann, Taís Silveira;
Milagro, Fermín I.;
Martínez, José Alfredo

Publication type:

Article

Antiproliferative and pro-apoptotic effects of Cyclocarya paliurus polysaccharide and X-ray irradiation combination on SW480 colorectal cancer cells.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3535, doi. 10.3892/mmr.2019.10642

By:

Jin, Yongjun;
Jin, Zhezhu;
Jiang, Sanya

Publication type:

Article

Overexpression of microRNA-155 alleviates palmitate-induced vascular endothelial cell injury in human umbilical vein endothelial cells by negatively regulating the Wnt signaling pathway.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3527, doi. 10.3892/mmr.2019.10623

By:

Zhao, Yanping;
Rao, Wenquan;
Wan, Yanna;
Yang, Xinglong;
Wang, Guorong;
Deng, Jun;
Dai, Min;
Liu, Qiang

Publication type:

Article

MicroRNA-608 sensitizes non-small cell lung cancer cells to cisplatin by targeting TEAD2.

Published in:

Molecular Medicine Reports, 2019, v. 20, n. 4, p. 3519, doi. 10.3892/mmr.2019.10616

By:

Wang, Yanli;
Li, Fengcai;
Ma, Dandan;
Gao, Yuhua;
Li, Runpu;
Gao, Yingjie

Publication type:

Article