Works in Molecular Medicine Reports, 2018, Vol 17, Issue 1

Results: 263

SRPK1-siRNA suppresses K562 cell growth and induces apoptosis via the PARP-caspase3 pathway.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 2070, doi. 10.3892/mmr.2017.8032

By:

Wang, Hailian;
Ge, Wei;
Jiang, Wen;
Li, Dong;
Ju, Xiuli

Publication type:

Article

Mechanism of free radical generation in platelets and primary hepatocytes: A novel electron spin resonance study.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 2061, doi. 10.3892/mmr.2017.8058

By:

Wang, Chiun-Lang;
Yang, Po-Sheng;
Tsao, Jeng-Ting;
Jayakumar, Thanasekaran;
Wang, Meng-Jiy;
Sheu, Joen-Rong;
Chou, Duen-Suey

Publication type:

Article

miR-660-5p is associated with cell migration, invasion, proliferation and apoptosis in renal cell carcinoma.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 2051, doi. 10.3892/mmr.2017.8052

By:

He, Tao;
Chen, Peijie;
Jin, Lu;
Hu, Jia;
Li, Yifan;
Zhou, Liang;
Yang, Shangqi;
Mao, Xiangming;
Gui, Yaoting;
Chen, Yun;
Lai, Yongqing

Publication type:

Article

Cellular properties of the fermented microalgae Pavlova lutheri and its isolated active peptide in osteoblastic differentiation of MG-63 cells.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 2044, doi. 10.3892/mmr.2017.8087

By:

Qian, Zhong-Ji;
Ryu, Bomi;
Kang, Kyong-Hwa;
Heo, Soo-Jin;
Kang, Do-Hyung;
Bae, Sung Yong;
Park, Sun-Joo;
Kim, Jae-Il;
Kim, Young-Mog;
Kim, Yong-Tae;
Jung, Won-Kyo

Publication type:

Article

The role of dual-specificity phosphatase 1 and protein phosphatase 1 in β2-adrenergic receptor-mediated inhibition of extracellular signal regulated kinase 1/2 in triple negative breast cancer cell lines.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 2033, doi. 10.3892/mmr.2017.8092

By:

Tuglu, Matilda Merve;
Bostanabad, Saber Yari;
Ozyon, Gozde;
Dalkiliç, Başak;
Gurdal, Hakan

Publication type:

Article

Gambogic acid inhibits spinal cord injury and inflammation through suppressing the p38 and Akt signaling pathways.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 2026, doi. 10.3892/mmr.2017.8026

By:

Fu, Qiao;
Li, Chaojian;
Yu, Lehua

Publication type:

Article

Curcumin reverses tobacco smoke-induced epithelial-mesenchymal transition by suppressing the MAPK pathway in the lungs of mice.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 2019, doi. 10.3892/mmr.2017.8028

By:

Liang, Zhaofeng;
Wu, Rui;
Xie, Wei;
Zhu, Mingming;
Xie, Chunfeng;
Li, Xiaoting;
Zhu, Jianyun;
Zhu, Weiwei;
Wu, Jieshu;
Geng, Shanshan;
Xu, Wenrong;
Zhong, Caiyun;
Han, Hongyu

Publication type:

Article

Neuroprotective effect of tanshinone IIA weakens spastic cerebral palsy through inflammation, p38MAPK and VEGF in neonatal rats.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 2012, doi. 10.3892/mmr.2017.8069

By:

Zhang, Wen-Luo;
Cao, Yue-An;
Xia, Jing;
Tian, Li;
Yang, Lu;
Peng, Chao-Sheng

Publication type:

Article

microRNA-625 targets Yes-associated protein 1 to suppress cell proliferation and invasion of osteosarcoma.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 2005, doi. 10.3892/mmr.2017.8079

By:

Luo, Zheng;
Wu, Gang;
Zhang, Daiyang;
Liu, Jun;
Ran, Renguo

Publication type:

Article

TWEAK/Fn14 promotes oxidative stress through AMPK/PGC-1α/MnSOD signaling pathway in endothelial cells.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1998, doi. 10.3892/mmr.2017.8090

By:

Liu, Hengdao;
Peng, Hui;
Xiang, Hong;
Guo, Lingli;
Chen, Ruifang;
Zhao, Shaoli;
Chen, Wei;
Chen, Pan;
Lu, Hongwei;
Chen, Shuhua

Publication type:

Article

Cytochrome c is important in apoptosis of labial glands in primary Sjogren's syndrome.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1993, doi. 10.3892/mmr.2017.8083

By:

Kang, Yuanyuan;
Sun, Yan;
Zhang, Ying;
Wang, Zhe

Publication type:

Article

Fli-1 promotes metastasis by regulating MMP2 signaling in hepatocellular carcinoma.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1986, doi. 10.3892/mmr.2017.8047

By:

Wang, Huiling;
Ou, Yingliang;
Ou, Jinrui;
Jian, Zhixiang

Publication type:

Article

The regulatory role of Fos related antigen-1 in inflammatory bowel disease.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1979, doi. 10.3892/mmr.2017.8071

By:

Wang, Xianren;
Guo, Renle;
Lv, Yanfeng;
Fu, Rongzhan

Publication type:

Article

iASPP, a microRNA-124 target, is aberrantly expressed in astrocytoma and regulates malignant glioma cell migration and viability.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1970, doi. 10.3892/mmr.2017.8097

By:

Liu, Xiangrong;
Kang, Jun;
Sun, Si;
Luo, Yumin;
Ji, Xunming;
Zeng, Xianwei;
Zhao, Shangfeng

Publication type:

Article

Curcumin improves diabetes mellitus-associated cerebral infarction by increasing the expression of GLUT1 and GLUT3.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1963, doi. 10.3892/mmr.2017.8085

By:

Xia, Mingyu;
Ye, Zankai;
Shi, Yanfeng;
Zhou, Libo;
Hua, Yang

Publication type:

Article

An RNA-sequencing study identifies candidate genes for angiotensin II-induced cardiac remodeling.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1954, doi. 10.3892/mmr.2017.8043

By:

Shu, Jin;
Liu, Zhanwen;
Jin, Li;
Wang, Haiya

Publication type:

Article

The long noncoding RNA cancer susceptibility candidate 2 inhibits tumor progression in osteosarcoma.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1947, doi. 10.3892/mmr.2017.8080

By:

Lu, Lingyun;
Dai, Zhehao;
Luo, Qing;
Lv, Guohua

Publication type:

Article

Long noncoding RNA-ATB promotes cell proliferation, migration and invasion in gastric cancer.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1940, doi. 10.3892/mmr.2017.8077

By:

Chen, Ying;
Wei, Guoqing;
Xia, Hongwei;
Tang, Qiulin;
Bi, Feng

Publication type:

Article

Effect of moesin phosphorylation on high-dose sphingosine-1-phosphate-induced endothelial responses.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1933, doi. 10.3892/mmr.2017.8029

By:

Xiao, Yan;
Wu, Jie;
Yuan, Yongjun;
Guo, Xiaohua;
Chen, Bo;
Huang, Qiaobing

Publication type:

Article

miR-218 inhibits the proliferation of human glioma cells through downregulation of Yin Yang 1.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1926, doi. 10.3892/mmr.2017.8063

By:

Gao, Yong;
Sun, Laisheng;
Wu, Zicheng;
Xuan, Chengmin;
Zhang, Junxia;
You, Yongping;
Chen, Xincheng

Publication type:

Article

Reduced miRNA-214 expression in oral mucosa contributes to the pathogenesis of oral lichen planus by targeting CD44.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1919, doi. 10.3892/mmr.2017.8019

By:

Zheng, Haiyan;
Li, Shaohui

Publication type:

Article

Overexpression of microRNA-146 protects against oxygenglucose deprivation/recovery-induced cardiomyocyte apoptosis by inhibiting the NF-κB/TNF-α signaling pathway.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1913, doi. 10.3892/mmr.2017.8073

By:

Zhang, Wenwu;
Shao, Mengmeng;
He, Xiaojie;
Wang, Benji;
Li, Yuechun;
Guo, Xianyang

Publication type:

Article

Protective effects of oxymatrine against lipopolysaccharide/D-galactosamine-induced acute liver failure through oxidative damage, via activation of Nrf2/HO-1 and modulation of inflammatory TLR4-signaling pathways.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1907, doi. 10.3892/mmr.2017.8060

By:

Xu, Jian;
Li, Chengmin;
Li, Ziwei;
Yang, Chan;
Lei, Lan;
Ren, Wei;
Su, Yan;
Chen, Chunping

Publication type:

Article

Anti-inflammatory effect of Migri-Heal® in an in vitro inflammatory model of primary mixed glial cells.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1901, doi. 10.3892/mmr.2017.8027

By:

Hassani, Mahmoud;
Sabouni, Farzaneh;
Ansari, Mohammad;
Emamgholipour, Solaleh;
Fallah, Mohammad-Sadegh;
Abbasi, Shah-Sanam;
Majd, Saeed Ansari

Publication type:

Article

Modulation of TGF-β activity by latent TGF-β-binding protein 1 in human osteoarthritis fibroblast-like synoviocytes.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1893, doi. 10.3892/mmr.2017.8086

By:

Wang, Xinli;
Dong, Chuan;
Li, Nan;
Ma, Qiong;
Yun, Zhe;
Cai, Chengkui;
An, Ming;
Ma, Baoan

Publication type:

Article

Simvastatin ameliorates cognitive impairments via inhibition of oxidative stress-induced apoptosis of hippocampal cells through the ERK/AKT signaling pathway in a rat model of senile dementia.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1885, doi. 10.3892/mmr.2017.8098

By:

Liu, Wenting;
Zhao, Yan;
Zhang, Xinyu;
Ji, Jiangang

Publication type:

Article

The -α3.7 deletion in α-globin genes increases the concentration of fetal hemoglobin and hemoglobin A2 in a Saudi Arabian population.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1879, doi. 10.3892/mmr.2017.8033

By:

Borgio, J. Francis;
Abdulazeez, Sayed;
Almandil, Noor B.;
Naserullah, Zaki A.;
Al-Jarrash, Sana;
Al-Suliman, Ahmed M.;
Elfakharay, Huda Ismail;
Qaw, Fuad S.;
Alabdrabalnabi, Fatimah I.;
Alkhalifah, Mohammed A.;
Akhtar, Mohammed Shakil;
Qutub, Hatem;
Al-Ali, Amein K.

Publication type:

Article

Differentially expressed proteins in the human esophageal cancer cell line Eca-109, in the presence and absence of gemcitabine.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1873, doi. 10.3892/mmr.2017.8041

By:

Ma, Zenghuang;
Xue, Xiaojie

Publication type:

Article

Beneficial effect of resveratrol on α-naphthyl isothiocyanate-induced cholestasis via regulation of the FXR pathway.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1863, doi. 10.3892/mmr.2017.8051

By:

Ding, Lili;
Zhang, Binfeng;
Li, Jinmei;
Yang, Li;
Wang, Zhengtao

Publication type:

Article

Mechanical strain promotes osteogenic differentiation of bone mesenchymal stem cells from ovariectomized rats via the phosphoinositide 3-kinase/Akt signaling pathway.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1855, doi. 10.3892/mmr.2017.8030

By:

Ouyang, Ningjuan;
Zhang, Peng;
Fu, Runqing;
Shen, Guofang;
Jiang, Lingyong;
Fang, Bing

Publication type:

Article

Long noncoding RNA Lnc-EGFR promotes cell proliferation and inhibits cell apoptosis via regulating the expression of EGFR in human tongue cancer.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1847, doi. 10.3892/mmr.2017.8031

By:

Sun, Tingting;
Tang, Lin;
Zhang, Miaomiao

Publication type:

Article

Effects of SCN9A gene modification on Na+ channel and the expression of nerve growth factor in a rat model of diarrhea-predominant irritable bowel syndrome.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1839, doi. 10.3892/mmr.2017.8061

By:

Cai, Yong-Yan;
Li, Chen;
Yan, Zhi-Xin;
Ma, Na;
Li, Fang-Fang

Publication type:

Article

Integrated bioinformatics analysis of the osteoarthritis-associated microRNA expression signature.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1833, doi. 10.3892/mmr.2017.8057

By:

Wang, Xi;
Ning, Yujie;
Zhou, Bing;
Yang, Lei;
Wang, Yingting;
Guo, Xiong

Publication type:

Article

miR-455-5p promotes cell invasion and migration in breast cancer.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1825, doi. 10.3892/mmr.2017.8101

By:

Aili, Tuerxunjiang;
Paizula, Xuelaiti;
Ayoufu, Aisikeer

Publication type:

Article

P2Y1 receptor antagonists mitigate oxygen and glucose deprivation-induced astrocyte injury.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1819, doi. 10.3892/mmr.2017.8072

By:

Guo, Hui;
Liu, Zhong-Qiang;
Zhou, Hui;
Wang, Zhi-Ling;
Tao, Yu-Hong;
Tong, Yu

Publication type:

Article

Protective effects of fucoidan against hyperoxic lung injury via the ERK signaling pathway.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1813, doi. 10.3892/mmr.2017.8022

By:

Nie, Minghao;
Wang, Yan;
Lu, Yanhong;
Yuan, Ying;
Liu, Yingying;
Li, Xiurong

Publication type:

Article

Homology modeling and prediction of B-cell and T-cell epitopes of the house dust mite allergen Der f 20.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1807, doi. 10.3892/mmr.2017.8066

By:

Teng, Feixiang;
Yu, Lili;
Sun, Jinxia;
Wang, Nan;
Cui, Yubao

Publication type:

Article

Grape seed proanthocyanidin extract attenuates varicocele-induced testicular oxidative injury in rats by activating the Nrf2-antioxidant system.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1799, doi. 10.3892/mmr.2017.8020

By:

Wang, Yong;
Chen, Fan;
Liang, Ming;
Chen, Shouzhen;
Zhu, Yaofeng;
Zou, Zhichuan;
Shi, Benkang

Publication type:

Article

Elevated serum levels of lipoprotein-associated phospholipase A2 predict mortality rates in patients with sepsis.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1791, doi. 10.3892/mmr.2017.8034

By:

Huang, Zhongwei;
Jiang, Haiyan;
Cui, Xiaohui;
Liang, Guiwen;
Chen, Yu;
Wang, Ting;
Sun, Zhichao;
Qi, Lei

Publication type:

Article

Application of next-generation sequencing to identify mitochondrial mutations: Study on m.7511T>C in patients with hearing loss.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1782, doi. 10.3892/mmr.2017.8064

By:

Lechowicz, Urszula;
Pollak, Agnieszka;
Frączak, Agnieszka;
Rydzanicz, Małgorzata;
Stawiński, Piotr;
Lorens, Artur;
Skarżyński, Piotr H.;
Skarżyński, Henryk;
Płoski, Rafał;
Ołdak, Monika

Publication type:

Article

Matrine suppresses cardiac fibrosis by inhibiting the TGF-β/Smad pathway in experimental diabetic cardiomyopathy.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1775, doi. 10.3892/mmr.2017.8054

By:

Zhang, Yong;
Cui, Lei;
Guan, Gongchang;
Wang, Junkui;
Qiu, Chuan;
Yang, Tielin;
Guo, Yan;
Liu, Zhongwei

Publication type:

Article

SK channels participate in the formation of after burst hyperpolarization and partly inhibit the burst strength of epileptic ictal discharges.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1762, doi. 10.3892/mmr.2017.8068

By:

Huang, Yian;
Liu, Xu;
Wang, Guoxiang;
Wang, Yun

Publication type:

Article

Effect of prehypertensive losartan therapy on AT1R and ATRAP methylation of adipose tissue in the later life of high-fat-fed spontaneously hypertensive rats.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1753, doi. 10.3892/mmr.2017.8081

By:

Wang, Tingjun;
Lian, Guili;
Cai, Xiaoqi;
Lin, Zhihong;
Xie, Liangdi

Publication type:

Article

miR-185 inhibits non-small cell lung cancer cell proliferation and invasion through targeting of SOX9 and regulation of Wnt signaling.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1742, doi. 10.3892/mmr.2017.8050

By:

Lei, Zhengwen;
Shi, Hongcan;
Li, Wei;
Yu, Duonan;
Shen, Feiyang;
Yu, Xi;
Lu, Dan;
Sun, Chao;
Liao, Kai

Publication type:

Article

Therapeutic effects of mesenchymal stem cells combined with short hairpin RNA on liver injury induced by hepatitis B virus infection.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1731, doi. 10.3892/mmr.2017.8096

By:

Liu, Di;
Liu, Lin;
Wang, Lizheng;
Duan, Sizhu;
Song, Yanan;
Qu, Meng;
Gao, Nan;
Wu, Jiaxin;
Zhang, Haihong;
Wu, Hui;
Kong, Wei;
Yu, Bin;
Yu, Xianghui

Publication type:

Article

Effect of cigarette smoke extract and nicotine on the expression of thrombomodulin and endothelial protein C receptor in cultured human umbilical vein endothelial cells.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1724, doi. 10.3892/mmr.2017.8070

By:

Wei, Yujie;
Lai, Bin;
Liu, Huiliang;
Li, Yi;
Zhen, Wang;
Fu, Ling

Publication type:

Article

Therapeutic effect of ulinastatin on pulmonary fibrosis via downregulation of TGF-β1, TNF-α and NF-κB.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1717, doi. 10.3892/mmr.2017.8056

By:

Li, Dejun;
Ji, Hongsheng;
Zhao, Bao;
Xu, Chunyang;
Xia, Wenjun;
Han, Lihui;
Yu, Dongqing;
Ju, Yuanrong;
Jin, Changjun

Publication type:

Article

NG25, an inhibitor of transforming growth factor-β-activated kinase 1, ameliorates neuronal apoptosis in neonatal hypoxic-ischemic rats.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1710, doi. 10.3892/mmr.2017.8024

By:

Wang, Hua;
Chen, Zhong;
Li, Yu;
Ji, Qiaoyun

Publication type:

Article

INSIG2 rs7566605 single nucleotide variant and global DNA methylation index levels are associated with weight loss in a personalized weight reduction program.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1699, doi. 10.3892/mmr.2017.8039

By:

Pirini, Francesca;
Rodriguez-Torres, Sebastian;
Ayandibu, Bola Grace;
Orera-Clemente, María;
Vega, Alberto Gonzalez-De La;
Lawson, Fahcina;
Jr, Roland J. Thorpe;
Sidransky, David;
Guerrero-Preston, Rafael

Publication type:

Article

SUMO1/UBC9-decreased Nox1 activity inhibits reactive oxygen species generation and apoptosis in diabetic retinopathy.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 1, p. 1690, doi. 10.3892/mmr.2017.8037

By:

Hu, Jiaoli;
Xue, Pengcheng;
Mao, Xinbang;
Xie, Lin;
Li, Guodong;
You, Zhipeng

Publication type:

Article