Works matching IS 17574676 AND DT 2018 AND VI 10 AND IP 1

Results: 13

Targeting RNA G‐quadruplexes as new treatment strategy for <italic>C9orf72 </italic>ALS/FTD.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 4, doi. 10.15252/emmm.201708572

By:

Schludi, Martin H.;
Edbauer, Dieter

Publication type:

Article

Could blocking the formation of amyloid channels rescue Alzheimer's phenotype?

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 7, doi. 10.15252/emmm.201708491

By:

Guix, Francesc X.;
Dotti, Carlos G.

Publication type:

Article

Thrombopoietin: tickling the HSC's fancy.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 10, doi. 10.15252/emmm.201708450

By:

Kim, Ah Ram;
Sankaran, Vijay G.

Publication type:

Article

Patients with rare diseases: from therapeutic orphans to pioneers of personalized treatments.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 1, doi. 10.15252/emmm.201708365

By:

Klein, Christoph;
Gahl, William A.

Publication type:

Article

Ceruloplasmin replacement therapy ameliorates neurological symptoms in a preclinical model of aceruloplasminemia.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 91, doi. 10.15252/emmm.201708361

By:

Zanardi, Alan;
Conti, Antonio;
Cremonesi, Marco;
D'Adamo, Patrizia;
Gilberti, Enrica;
Apostoli, Pietro;
Cannistraci, Carlo Vittorio;
Piperno, Alberto;
David, Samuel;
Alessio, Massimo

Publication type:

Article

A proteomic network approach across the ALS‐FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 48, doi. 10.15252/emmm.201708202

By:

Umoh, Mfon E.;
Dammer, Eric B.;
Dai, Jingting;
Duong, Duc M.;
Lah, James J.;
Levey, Allan I.;
Gearing, Marla;
Glass, Jonathan D.;
Seyfried, Nicholas T.

Publication type:

Article

Thrombopoietin mutation in congenital amegakaryocytic thrombocytopenia treatable with romiplostim.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 63, doi. 10.15252/emmm.201708168

By:

Pecci, Alessandro;
Ragab, Iman;
Bozzi, Valeria;
De Rocco, Daniela;
Barozzi, Serena;
Giangregorio, Tania;
Ali, Heba;
Melazzini, Federica;
Sallam, Mohamed;
Alfano, Caterina;
Pastore, Annalisa;
Balduini, Carlo L.;
Savoia, Anna

Publication type:

Article

The diphenylpyrazole compound anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 32, doi. 10.15252/emmm.201707825

By:

Martinez Hernandez, Ana;
Urbanke, Hendrik;
Gillman, Alan L.;
Lee, Joon;
Ryazanov, Sergey;
Agbemenyah, Hope Y.;
Benito, Eva;
Jain, Gaurav;
Kaurani, Lalit;
Grigorian, Gayane;
Leonov, Andrei;
Rezaei‐Ghaleh, Nasrollah;
Wilken, Petra;
Arce, Fernando Teran;
Wagner, Jens;
Fuhrman, Martin;
Caruana, Mario;
Camilleri, Angelique;
Vassallo, Neville;
Zweckstetter, Markus

Publication type:

Article

Photoreceptor glucose metabolism determines normal retinal vascular growth.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 76, doi. 10.15252/emmm.201707966

By:

Fu, Zhongjie;
Löfqvist, Chatarina A.;
Liegl, Raffael;
Wang, Zhongxiao;
Sun, Ye;
Gong, Yan;
Liu, Chi‐Hsiu;
Meng, Steven S.;
Burnim, Samuel B.;
Arellano, Ivana;
Chouinard, My T.;
Duran, Rubi;
Poblete, Alexander;
Cho, Steve S.;
Akula, James D.;
Kinter, Michael;
Ley, David;
Pupp, Ingrid Hansen;
Talukdar, Saswata;
Hellström, Ann

Publication type:

Article

Co‐infection with Chikungunya virus alters trafficking of pathogenic CD8<sup>+</sup> T cells into the brain and prevents <italic>Plasmodium</italic>‐induced neuropathology.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 121, doi. 10.15252/emmm.201707885

By:

Teo, Teck‐Hui;
Howland, Shanshan W.;
Claser, Carla;
Gun, Sin Yee;
Poh, Chek Meng;
Lee, Wendy W. L.;
Lum, Fok‐Moon;
Ng, Lisa F. P.;
Rénia, Laurent

Publication type:

Article

Genomic structural variations lead to dysregulation of important coding and non‐coding RNA species in dilated cardiomyopathy.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 107, doi. 10.15252/emmm.201707838

By:

Haas, Jan;
Mester, Stefan;
Lai, Alan;
Frese, Karen S.;
Sedaghat‐Hamedani, Farbod;
Kayvanpour, Elham;
Rausch, Tobias;
Nietsch, Rouven;
Boeckel, Jes‐Niels;
Carstensen, Avisha;
Völkers, Mirko;
Dietrich, Carsten;
Pils, Dietmar;
Amr, Ali;
Holzer, Daniel B.;
Martins Bordalo, Diana;
Oehler, Daniel;
Weis, Tanja;
Mereles, Derliz;
Buss, Sebastian

Publication type:

Article

A complex genomic locus drives mtDNA replicase POLG expression to its disease‐related nervous system regions.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 13, doi. 10.15252/emmm.201707993

By:

Nikkanen, Joni;
Landoni, Juan Cruz;
Balboa, Diego;
Haugas, Maarja;
Partanen, Juha;
Paetau, Anders;
Isohanni, Pirjo;
Brilhante, Virginia;
Suomalainen, Anu

Publication type:

Article

G‐quadruplex‐binding small molecules ameliorate <italic>C9orf72 </italic>FTD/ALS pathology <italic>in vitro</italic> and <italic>in vivo</italic>.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 22, doi. 10.15252/emmm.201707850

By:

Simone, Roberto;
Balendra, Rubika;
Moens, Thomas G.;
Preza, Elisavet;
Wilson, Katherine M.;
Heslegrave, Amanda;
Woodling, Nathan S.;
Niccoli, Teresa;
Gilbert‐Jaramillo, Javier;
Abdelkarim, Samir;
Clayton, Emma L.;
Clarke, Mica;
Konrad, Marie‐Therese;
Nicoll, Andrew J.;
Mitchell, Jamie S.;
Calvo, Andrea;
Chio, Adriano;
Houlden, Henry;
Polke, James M.;
Ismail, Mohamed A.

Publication type:

Article