Works matching IS 17574676 AND DT 2018 AND VI 10 AND IP 1

Results: 13

A complex genomic locus drives mtDNA replicase POLG expression to its disease‐related nervous system regions.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 13, doi. 10.15252/emmm.201707993
By:
- Nikkanen, Joni;
- Landoni, Juan Cruz;
- Balboa, Diego;
- Haugas, Maarja;
- Partanen, Juha;
- Paetau, Anders;
- Isohanni, Pirjo;
- Brilhante, Virginia;
- Suomalainen, Anu
Publication type:
Article
Targeting RNA G‐quadruplexes as new treatment strategy for <italic>C9orf72 </italic>ALS/FTD.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 4, doi. 10.15252/emmm.201708572
By:
- Schludi, Martin H.;
- Edbauer, Dieter
Publication type:
Article
Could blocking the formation of amyloid channels rescue Alzheimer's phenotype?
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 7, doi. 10.15252/emmm.201708491
By:
- Guix, Francesc X.;
- Dotti, Carlos G.
Publication type:
Article
Thrombopoietin: tickling the HSC's fancy.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 10, doi. 10.15252/emmm.201708450
By:
- Kim, Ah Ram;
- Sankaran, Vijay G.
Publication type:
Article
Ceruloplasmin replacement therapy ameliorates neurological symptoms in a preclinical model of aceruloplasminemia.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 91, doi. 10.15252/emmm.201708361
By:
- Zanardi, Alan;
- Conti, Antonio;
- Cremonesi, Marco;
- D'Adamo, Patrizia;
- Gilberti, Enrica;
- Apostoli, Pietro;
- Cannistraci, Carlo Vittorio;
- Piperno, Alberto;
- David, Samuel;
- Alessio, Massimo
Publication type:
Article
Thrombopoietin mutation in congenital amegakaryocytic thrombocytopenia treatable with romiplostim.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 63, doi. 10.15252/emmm.201708168
By:
- Pecci, Alessandro;
- Ragab, Iman;
- Bozzi, Valeria;
- De Rocco, Daniela;
- Barozzi, Serena;
- Giangregorio, Tania;
- Ali, Heba;
- Melazzini, Federica;
- Sallam, Mohamed;
- Alfano, Caterina;
- Pastore, Annalisa;
- Balduini, Carlo L.;
- Savoia, Anna
Publication type:
Article
A proteomic network approach across the ALS‐FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 48, doi. 10.15252/emmm.201708202
By:
- Umoh, Mfon E.;
- Dammer, Eric B.;
- Dai, Jingting;
- Duong, Duc M.;
- Lah, James J.;
- Levey, Allan I.;
- Gearing, Marla;
- Glass, Jonathan D.;
- Seyfried, Nicholas T.
Publication type:
Article
Photoreceptor glucose metabolism determines normal retinal vascular growth.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 76, doi. 10.15252/emmm.201707966
By:
- Fu, Zhongjie;
- Löfqvist, Chatarina A.;
- Liegl, Raffael;
- Wang, Zhongxiao;
- Sun, Ye;
- Gong, Yan;
- Liu, Chi‐Hsiu;
- Meng, Steven S.;
- Burnim, Samuel B.;
- Arellano, Ivana;
- Chouinard, My T.;
- Duran, Rubi;
- Poblete, Alexander;
- Cho, Steve S.;
- Akula, James D.;
- Kinter, Michael;
- Ley, David;
- Pupp, Ingrid Hansen;
- Talukdar, Saswata;
- Hellström, Ann
Publication type:
Article
Patients with rare diseases: from therapeutic orphans to pioneers of personalized treatments.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 1, doi. 10.15252/emmm.201708365
By:
- Klein, Christoph;
- Gahl, William A.
Publication type:
Article
Co‐infection with Chikungunya virus alters trafficking of pathogenic CD8<sup>+</sup> T cells into the brain and prevents <italic>Plasmodium</italic>‐induced neuropathology.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 121, doi. 10.15252/emmm.201707885
By:
- Teo, Teck‐Hui;
- Howland, Shanshan W.;
- Claser, Carla;
- Gun, Sin Yee;
- Poh, Chek Meng;
- Lee, Wendy W. L.;
- Lum, Fok‐Moon;
- Ng, Lisa F. P.;
- Rénia, Laurent
Publication type:
Article
Genomic structural variations lead to dysregulation of important coding and non‐coding RNA species in dilated cardiomyopathy.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 107, doi. 10.15252/emmm.201707838
By:
- Haas, Jan;
- Mester, Stefan;
- Lai, Alan;
- Frese, Karen S.;
- Sedaghat‐Hamedani, Farbod;
- Kayvanpour, Elham;
- Rausch, Tobias;
- Nietsch, Rouven;
- Boeckel, Jes‐Niels;
- Carstensen, Avisha;
- Völkers, Mirko;
- Dietrich, Carsten;
- Pils, Dietmar;
- Amr, Ali;
- Holzer, Daniel B.;
- Martins Bordalo, Diana;
- Oehler, Daniel;
- Weis, Tanja;
- Mereles, Derliz;
- Buss, Sebastian
Publication type:
Article
The diphenylpyrazole compound anle138b blocks Aβ channels and rescues disease phenotypes in a mouse model for amyloid pathology.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 32, doi. 10.15252/emmm.201707825
By:
- Martinez Hernandez, Ana;
- Urbanke, Hendrik;
- Gillman, Alan L.;
- Lee, Joon;
- Ryazanov, Sergey;
- Agbemenyah, Hope Y.;
- Benito, Eva;
- Jain, Gaurav;
- Kaurani, Lalit;
- Grigorian, Gayane;
- Leonov, Andrei;
- Rezaei‐Ghaleh, Nasrollah;
- Wilken, Petra;
- Arce, Fernando Teran;
- Wagner, Jens;
- Fuhrman, Martin;
- Caruana, Mario;
- Camilleri, Angelique;
- Vassallo, Neville;
- Zweckstetter, Markus
Publication type:
Article
G‐quadruplex‐binding small molecules ameliorate <italic>C9orf72 </italic>FTD/ALS pathology <italic>in vitro</italic> and <italic>in vivo</italic>.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 1, p. 22, doi. 10.15252/emmm.201707850
By:
- Simone, Roberto;
- Balendra, Rubika;
- Moens, Thomas G.;
- Preza, Elisavet;
- Wilson, Katherine M.;
- Heslegrave, Amanda;
- Woodling, Nathan S.;
- Niccoli, Teresa;
- Gilbert‐Jaramillo, Javier;
- Abdelkarim, Samir;
- Clayton, Emma L.;
- Clarke, Mica;
- Konrad, Marie‐Therese;
- Nicoll, Andrew J.;
- Mitchell, Jamie S.;
- Calvo, Andrea;
- Chio, Adriano;
- Houlden, Henry;
- Polke, James M.;
- Ismail, Mohamed A.
Publication type:
Article