Works matching IS 17574676 AND DT 2017 AND VI 9 AND IP 10

Results: 12

Promoterless gene targeting without nucleases rescues lethality of a Crigler-Najjar syndrome mouse model.
Published in:
EMBO Molecular Medicine, 2017, v. 9, n. 10, p. 1346, doi. 10.15252/emmm.201707601
By:
- Porro, Fabiola;
- Bortolussi, Giulia;
- Barzel, Adi;
- De Caneva, Alessia;
- Iaconcig, Alessandra;
- Vodret, Simone;
- Zentilin, Lorena;
- Kay, Mark A;
- Muro, Andrés F
Publication type:
Article
An Alzheimer-associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function.
Published in:
EMBO Molecular Medicine, 2017, v. 9, n. 10, p. 1356, doi. 10.15252/emmm.201707672
By:
- Schlepckow, Kai;
- Kleinberger, Gernot;
- Fukumori, Akio;
- Feederle, Regina;
- Lichtenthaler, Stefan F;
- Steiner, Harald;
- Haass, Christian
Publication type:
Article
TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant.
Published in:
EMBO Molecular Medicine, 2017, v. 9, n. 10, p. 1366, doi. 10.15252/emmm.201707673
By:
- Thornton, Peter;
- Sevalle, Jean;
- Deery, Michael J;
- Fraser, Graham;
- Zhou, Ye;
- Ståhl, Sara;
- Franssen, Elske H;
- Dodd, Roger B;
- Qamar, Seema;
- Gomez Perez‐Nievas, Beatriz;
- Nicol, Louise SC;
- Eketjäll, Susanna;
- Revell, Jefferson;
- Jones, Clare;
- Billinton, Andrew;
- St George‐Hyslop, Peter H;
- Chessell, Iain;
- Crowther, Damian C
Publication type:
Article
mRNA mediates passive vaccination against infectious agents, toxins, and tumors.
Published in:
EMBO Molecular Medicine, 2017, v. 9, n. 10, p. 1434, doi. 10.15252/emmm.201707678
By:
- Thran, Moritz;
- Mukherjee, Jean;
- Pönisch, Marion;
- Fiedler, Katja;
- Thess, Andreas;
- Mui, Barbara L;
- Hope, Michael J;
- Tam, Ying K;
- Horscroft, Nigel;
- Heidenreich, Regina;
- Fotin‐Mleczek, Mariola;
- Shoemaker, Charles B;
- Schlake, Thomas
Publication type:
Article
β-Klotho sustains postnatal Gn RH biology and spins the thread of puberty.
Published in:
EMBO Molecular Medicine, 2017, v. 9, n. 10, p. 1334, doi. 10.15252/emmm.201708180
By:
- Misrahi, Micheline
Publication type:
Article
Spironolactone is an antagonist of NRG1- ERBB4 signaling and schizophrenia-relevant endophenotypes in mice.
Published in:
EMBO Molecular Medicine, 2017, v. 9, n. 10, p. 1448, doi. 10.15252/emmm.201707691
By:
- Wehr, Michael C;
- Hinrichs, Wilko;
- Brzózka, Magdalena M;
- Unterbarnscheidt, Tilmann;
- Herholt, Alexander;
- Wintgens, Jan P;
- Papiol, Sergi;
- Soto‐Bernardini, Maria Clara;
- Kravchenko, Mykola;
- Zhang, Mingyue;
- Nave, Klaus‐Armin;
- Wichert, Sven P;
- Falkai, Peter;
- Zhang, Weiqi;
- Schwab, Markus H;
- Rossner, Moritz J
Publication type:
Article
One level up: abnormal proteolytic regulation of IGF activity plays a role in human pathophysiology.
Published in:
EMBO Molecular Medicine, 2017, v. 9, n. 10, p. 1338, doi. 10.15252/emmm.201707950
By:
- Argente, Jesús;
- Chowen, Julie A;
- Pérez‐Jurado, Luis A;
- Frystyk, Jan;
- Oxvig, Claus
Publication type:
Article
BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity.
Published in:
EMBO Molecular Medicine, 2017, v. 9, n. 10, p. 1398, doi. 10.15252/emmm.201607446
By:
- Tacconi, Eliana MC;
- Lai, Xianning;
- Folio, Cecilia;
- Porru, Manuela;
- Zonderland, Gijs;
- Badie, Sophie;
- Michl, Johanna;
- Sechi, Irene;
- Rogier, Mélanie;
- Matía García, Verónica;
- Batra, Ankita Sati;
- Rueda, Oscar M;
- Bouwman, Peter;
- Jonkers, Jos;
- Ryan, Anderson;
- Reina‐San‐Martin, Bernardo;
- Hui, Joannie;
- Tang, Nelson;
- Bruna, Alejandra;
- Biroccio, Annamaria
Publication type:
Article
CDK6 protects epithelial ovarian cancer from platinum-induced death via FOXO3 regulation.
Published in:
EMBO Molecular Medicine, 2017, v. 9, n. 10, p. 1415, doi. 10.15252/emmm.201607012
By:
- Dall'Acqua, Alessandra;
- Sonego, Maura;
- Pellizzari, Ilenia;
- Pellarin, Ilenia;
- Canzonieri, Vincenzo;
- D'Andrea, Sara;
- Benevol, Sara;
- Sorio, Roberto;
- Giorda, Giorgio;
- Califano, Daniela;
- Bagnoli, Marina;
- Militello, Loredana;
- Mezzanzanica, Delia;
- Chiappetta, Gennaro;
- Armenia, Joshua;
- Belletti, Barbara;
- Schiappacassi, Monica;
- Baldassarre, Gustavo
Publication type:
Article
Thwarting endogenous stress: BRCA protects against aldehyde toxicity.
Published in:
EMBO Molecular Medicine, 2017, v. 9, n. 10, p. 1331, doi. 10.15252/emmm.201708194
By:
- Ray Chaudhuri, Arnab;
- Nussenzweig, André
Publication type:
Article
Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses.
Published in:
EMBO Molecular Medicine, 2017, v. 9, n. 10, p. 1327, doi. 10.15252/emmm.201708072
By:
- Teixeira, Andre A;
- Marchiò, Serena;
- Dias‐Neto, Emmanuel;
- Nunes, Diana N;
- da Silva, Israel T;
- Chackerian, Bryce;
- Barry, Marc;
- Lauer, Richard C;
- Giordano, Ricardo J;
- Sidman, Richard L;
- Wheeler, Cosette M;
- Cavenee, Webster K;
- Pasqualini, Renata;
- Arap, Wadih
Publication type:
Article
KLB, encoding β-Klotho, is mutated in patients with congenital hypogonadotropic hypogonadism.
Published in:
EMBO Molecular Medicine, 2017, v. 9, n. 10, p. 1379, doi. 10.15252/emmm.201607376
By:
- Xu, Cheng;
- Messina, Andrea;
- Somm, Emmanuel;
- Miraoui, Hichem;
- Kinnunen, Tarja;
- Acierno, James;
- Niederländer, Nicolas J;
- Bouilly, Justine;
- Dwyer, Andrew A;
- Sidis, Yisrael;
- Cassatella, Daniele;
- Sykiotis, Gerasimos P;
- Quinton, Richard;
- De Geyter, Christian;
- Dirlewanger, Mirjam;
- Schwitzgebel, Valérie;
- Cole, Trevor R;
- Toogood, Andrew A;
- Kirk, Jeremy MW;
- Plummer, Lacey
Publication type:
Article