Works matching IS 17574676 AND DT 2015 AND VI 7 AND IP 2

Results: 7

Functional drug screening reveals anticonvulsants as enhancers of mTOR-independent autophagic killing of Mycobacterium tuberculosis through inositol depletion.

Published in:

EMBO Molecular Medicine, 2015, v. 7, n. 2, p. 127, doi. 10.15252/emmm.201404137

By:

Schiebler, Mark;
Brown, Karen;
Hegyi, Krisztina;
Newton, Sandra M;
Renna, Maurizio;
Hepburn, Lucy;
Klapholz, Catherine;
Coulter, Sarah;
Obregón‐Henao, Andres;
Henao Tamayo, Marcela;
Basaraba, Randall;
Kampmann, Beate;
Henry, Katherine M;
Burgon, Joseph;
Renshaw, Stephen A;
Fleming, Angeleen;
Kay, Robert R;
Anderson, Karen E;
Hawkins, Phillip T;
Ordway, Diane J

Publication type:

Article

Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation.

Published in:

EMBO Molecular Medicine, 2015, v. 7, n. 2, p. 190, doi. 10.15252/emmm.201404183

By:

Clarke, Julia R;
Lyra e Silva, Natalia M;
Figueiredo, Claudia P;
Frozza, Rudimar L;
Ledo, Jose H;
Beckman, Danielle;
Katashima, Carlos K;
Razolli, Daniela;
Carvalho, Bruno M;
Frazão, Renata;
Silveira, Marina A;
Ribeiro, Felipe C;
Bomfim, Theresa R;
Neves, Fernanda S;
Klein, William L;
Medeiros, Rodrigo;
LaFerla, Frank M;
Carvalheira, Jose B;
Saad, Mario J;
Munoz, Douglas P

Publication type:

Article

Impairment of chaperone-mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis.

Published in:

EMBO Molecular Medicine, 2015, v. 7, n. 2, p. 158, doi. 10.15252/emmm.201404223

By:

Napolitano, Gennaro;
Johnson, Jennifer L;
He, Jing;
Rocca, Celine J;
Monfregola, Jlenia;
Pestonjamasp, Kersi;
Cherqui, Stephanie;
Catz, Sergio D

Publication type:

Article

Modulation of TNF-α mRNA stability by human antigen R and miR181s in sepsis-induced immunoparalysis.

Published in:

EMBO Molecular Medicine, 2015, v. 7, n. 2, p. 140, doi. 10.15252/emmm.201404797

By:

Dan, Cao;
Jinjun, Bian;
Zi‐Chun, Hua;
Lin, Ma;
Wei, Chen;
Xu, Zhang;
Ri, Zhou;
Shun, Cheng;
Wen‐Zhu, Sun;
Qing‐Cai, Jiao;
Wu, Yin

Publication type:

Article

An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease.

Published in:

EMBO Molecular Medicine, 2015, v. 7, n. 2, p. 175, doi. 10.15252/emmm.201404438

By:

Kizuka, Yasuhiko;
Kitazume, Shinobu;
Fujinawa, Reiko;
Saito, Takashi;
Iwata, Nobuhisa;
Saido, Takaomi C;
Nakano, Miyako;
Yamaguchi, Yoshiki;
Hashimoto, Yasuhiro;
Staufenbiel, Matthias;
Hatsuta, Hiroyuki;
Murayama, Shigeo;
Manya, Hiroshi;
Endo, Tamao;
Taniguchi, Naoyuki

Publication type:

Article

New TB treatments hiding in plain sight.

Published in:

EMBO Molecular Medicine, 2015, v. 7, n. 2, p. 125, doi. 10.15252/emmm.201404815

By:

Olive, Andrew J;
Sassetti, Christopher M

Publication type:

Article

Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration.

Published in:

EMBO Molecular Medicine, 2015, v. 7, n. 2, p. 211, doi. 10.15252/emmm.201404524

By:

Levy, Olivier;
Calippe, Bertrand;
Lavalette, Sophie;
Hu, Shulong J;
Raoul, William;
Dominguez, Elisa;
Housset, Michael;
Paques, Michel;
Sahel, José‐Alain;
Bemelmans, Alexis‐Pierre;
Combadiere, Christophe;
Guillonneau, Xavier;
Sennlaub, Florian

Publication type:

Article