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Androgen receptor (AR) antagonism triggers acute succinate‐mediated adaptive responses to reactivate AR signaling.
Published in:
EMBO Molecular Medicine, 2021, v. 13, n. 5, p. 1, doi. 10.15252/emmm.202013427
By:
- Saxena, Neetu;
- Beraldi, Eliana;
- Fazli, Ladan;
- Somasekharan, Syam Prakash;
- Adomat, Hans;
- Zhang, Fan;
- Molokwu, Chidi;
- Gleave, Anna;
- Nappi, Lucia;
- Nguyen, Kimberly;
- Brar, Pavn;
- Nikesitch, Nicholas;
- Wang, Yuzhuo;
- Collins, Colin;
- Sorensen, Poul H;
- Gleave, Martin
Publication type:
Article
Neurodegenerative VPS41 variants inhibit HOPS function and mTORC1‐dependent TFEB/TFE3 regulation.
Published in:
EMBO Molecular Medicine, 2021, v. 13, n. 5, p. 1, doi. 10.15252/emmm.202013258
By:
- van der Welle, Reini E N;
- Jobling, Rebekah;
- Burns, Christian;
- Sanza, Paolo;
- van der Beek, Jan A;
- Fasano, Alfonso;
- Chen, Lan;
- Zwartkruis, Fried J;
- Zwakenberg, Susan;
- Griffin, Edward F;
- ten Brink, Corlinda;
- Veenendaal, Tineke;
- Liv, Nalan;
- van Ravenswaaij‐Arts, Conny M A;
- Lemmink, Henny H;
- Pfundt, Rolph;
- Blaser, Susan;
- Sepulveda, Carolina;
- Lozano, Andres M;
- Yoon, Grace
Publication type:
Article
Targeted genome editing in vivo corrects a Dmd duplication restoring wild‐type dystrophin expression.
Published in:
EMBO Molecular Medicine, 2021, v. 13, n. 5, p. 1, doi. 10.15252/emmm.202013228
By:
- Maino, Eleonora;
- Wojtal, Daria;
- Evagelou, Sonia L;
- Farheen, Aiman;
- Wong, Tatianna W Y;
- Lindsay, Kyle;
- Scott, Ori;
- Rizvi, Samar Z;
- Hyatt, Elzbieta;
- Rok, Matthew;
- Visuvanathan, Shagana;
- Chiodo, Amanda;
- Schneeweiss, Michelle;
- Ivakine, Evgueni A;
- Cohn, Ronald D
Publication type:
Article
Homotypic cell cannibalism, a cell‐death process regulated by the nuclear protein 1, opposes to metastasis in pancreatic cancer.
Published in:
EMBO Molecular Medicine, 2021, v. 13, n. 5, p. 1, doi. 10.15252/emmm.202114243
By:
- Cano, Carla E;
- José Sandí, María;
- Hamidi, Tewfik;
- Calvo, Ezequiel L;
- Turrini, Olivier;
- Bartholin, Laurent;
- Loncle, Céline;
- Secq, Véronique;
- Garcia, Stéphane;
- Lomberk, Gwen;
- Kroemer, Guido;
- Urrutia, Raul;
- Iovanna, Juan L
Publication type:
Article
High levels of circulating osteopontin in inflammatory lung disease regardless of Sars‐CoV‐2 infection.
Published in:
EMBO Molecular Medicine, 2021, v. 13, n. 5, p. 1, doi. 10.15252/emmm.202114124
By:
- Cappellano, Giuseppe;
- Abreu, Hugo;
- Raineri, Davide;
- Scotti, Lorenza;
- Castello, Luigi;
- Vaschetto, Rosanna;
- Chiocchetti, Annalisa
Publication type:
Article
Therapy resistance on the RADar in ovarian cancer.
Published in:
EMBO Molecular Medicine, 2021, v. 13, n. 5, p. 1, doi. 10.15252/emmm.202114010
By:
- Schwickert, Jonas;
- Zickgraf, Franziska M;
- Sprick, Martin R
Publication type:
Article
A positive feedback loop between mTORC1 and cathelicidin promotes skin inflammation in rosacea.
Published in:
EMBO Molecular Medicine, 2021, v. 13, n. 5, p. 1, doi. 10.15252/emmm.202013560
By:
- Deng, Zhili;
- Chen, Mengting;
- Liu, Yingzi;
- Xu, San;
- Ouyang, Yuyan;
- Shi, Wei;
- Jian, Dan;
- Wang, Ben;
- Liu, Fangfen;
- Li, Jinmao;
- Shi, Qian;
- Peng, Qinqin;
- Sha, Ke;
- Xiao, Wenqin;
- Liu, Tangxiele;
- Zhang, Yiya;
- Zhang, Hongbing;
- Wang, Qian;
- Sun, Lunquan;
- Xie, Hongfu
Publication type:
Article
Protein Kinase D2 drives chylomicron‐mediated lipid transport in the intestine and promotes obesity.
Published in:
EMBO Molecular Medicine, 2021, v. 13, n. 5, p. 1, doi. 10.15252/emmm.202013548
By:
- Trujillo‐Viera, Jonathan;
- El‐Merahbi, Rabih;
- Schmidt, Vanessa;
- Karwen, Till;
- Loza‐Valdes, Angel;
- Strohmeyer, Akim;
- Reuter, Saskia;
- Noh, Minhee;
- Wit, Magdalena;
- Hawro, Izabela;
- Mocek, Sabine;
- Fey, Christina;
- Mayer, Alexander E;
- Löffler, Mona C;
- Wilhelmi, Ilka;
- Metzger, Marco;
- Ishikawa, Eri;
- Yamasaki, Sho;
- Rau, Monika;
- Geier, Andreas
Publication type:
Article
Menin‐regulated Pbk controls high fat diet‐induced compensatory beta cell proliferation.
Published in:
EMBO Molecular Medicine, 2021, v. 13, n. 5, p. 1, doi. 10.15252/emmm.202013524
By:
- Ma, Jian;
- Xing, Bowen;
- Cao, Yan;
- He, Xin;
- Bennett, Kate E;
- Tong, Chao;
- An, Chiying;
- Hojnacki, Taylor;
- Feng, Zijie;
- Deng, Sunbin;
- Ling, Sunbin;
- Xie, Gengchen;
- Wu, Yuan;
- Ren, Yue;
- Yu, Ming;
- Katona, Bryson W;
- Li, Hongzhe;
- Naji, Ali;
- Hua, Xianxin
Publication type:
Article
CRISPR screens identify tumor‐promoting genes conferring melanoma cell plasticity and resistance.
Published in:
EMBO Molecular Medicine, 2021, v. 13, n. 5, p. 1, doi. 10.15252/emmm.202013466
By:
- Gautron, Arthur;
- Bachelot, Laura;
- Aubry, Marc;
- Leclerc, Delphine;
- Quéméner, Anaïs M;
- Corre, Sébastien;
- Rambow, Florian;
- Paris, Anaïs;
- Tardif, Nina;
- Leclair, Héloïse M;
- Marin‐Bejar, Oskar;
- Coulouarn, Cédric;
- Marine, Jean‐Christophe;
- Galibert, Marie‐Dominique;
- Gilot, David
Publication type:
Article
The immune suppressive microenvironment affects efficacy of radio‐immunotherapy in brain metastasis.
Published in:
EMBO Molecular Medicine, 2021, v. 13, n. 5, p. 1, doi. 10.15252/emmm.202013412
By:
- Niesel, Katja;
- Schulz, Michael;
- Anthes, Julian;
- Alekseeva, Tijna;
- Macas, Jadranka;
- Salamero‐Boix, Anna;
- Möckl, Aylin;
- Oberwahrenbrock, Timm;
- Lolies, Marco;
- Stein, Stefan;
- Plate, Karl H;
- Reiss, Yvonne;
- Rödel, Franz;
- Sevenich, Lisa
Publication type:
Article
Identification of TAPBPL as a novel negative regulator of T‐cell function.
Published in:
EMBO Molecular Medicine, 2021, v. 13, n. 5, p. 1, doi. 10.15252/emmm.202013404
By:
- Lin, Yujun;
- Cui, Cheng;
- Su, Min;
- Silbart, Lawrence K;
- Liu, Haiyan;
- Zhao, Jin;
- He, Lang;
- Huang, Yuanmao;
- Xu, Dexin;
- Wei, Xiaodan;
- Du, Qian;
- Lai, Laijun
Publication type:
Article
Bi‐allelic VPS16 variants limit HOPS/CORVET levels and cause a mucopolysaccharidosis‐like disease.
Published in:
EMBO Molecular Medicine, 2021, v. 13, n. 5, p. 1, doi. 10.15252/emmm.202013376
By:
- Sofou, Kalliopi;
- Meier, Kolja;
- Sanderson, Leslie E;
- Kaminski, Debora;
- Montoliu‐Gaya, Laia;
- Samuelsson, Emma;
- Blomqvist, Maria;
- Agholme, Lotta;
- Gärtner, Jutta;
- Mühlhausen, Chris;
- Darin, Niklas;
- Barakat, Tahsin Stefan;
- Schlotawa, Lars;
- Ham, Tjakko;
- Asin Cayuela, Jorge;
- Sterky, Fredrik H
Publication type:
Article
Quantitative imaging of RAD51 expression as a marker of platinum resistance in ovarian cancer.
Published in:
EMBO Molecular Medicine, 2021, v. 13, n. 5, p. 1, doi. 10.15252/emmm.202013366
By:
- Hoppe, Michal M;
- Jaynes, Patrick;
- Wardyn, Joanna D;
- Upadhyayula, Sai Srinivas;
- Tan, Tuan Zea;
- Lie, Stefanus;
- Lim, Diana G Z;
- Pang, Brendan N K;
- Lim, Sherlly;
- P S Yeong, Joe;
- Karnezis, Anthony;
- Chiu, Derek S;
- Leung, Samuel;
- Huntsman, David G;
- Sedukhina, Anna S;
- Sato, Ko;
- Topp, Monique D;
- Scott, Clare L;
- Choi, Hyungwon;
- Patel, Naina R
Publication type:
Article
Antioxidant nanozyme counteracts HIV‐1 by modulating intracellular redox potential.
Published in:
EMBO Molecular Medicine, 2021, v. 13, n. 5, p. 1, doi. 10.15252/emmm.202013314
By:
- Singh, Shalini;
- Ghosh, Sourav;
- Pal, Virender Kumar;
- Munshi, MohamedHusen;
- Shekar, Pooja;
- Narasimha Murthy, Diwakar Tumkur;
- Mugesh, Govindasamy;
- Singh, Amit
Publication type:
Article
miR‐33 in cardiometabolic diseases: lessons learned from novel animal models and approaches.
Published in:
EMBO Molecular Medicine, 2021, v. 13, n. 5, p. 1, doi. 10.15252/emmm.202012606
By:
- Price, Nathan L;
- Goedeke, Leigh;
- Suárez, Yajaira;
- Fernández‐Hernando, Carlos
Publication type:
Article
Myeloid‐resident neuropilin‐1 promotes choroidal neovascularization while mitigating inflammation.
Published in:
EMBO Molecular Medicine, 2021, v. 13, n. 5, p. 1, doi. 10.15252/emmm.201911754
By:
- Andriessen, Elisabeth M M A;
- Binet, François;
- Fournier, Frédérik;
- Hata, Masayuki;
- Dejda, Agnieszka;
- Mawambo, Gaëlle;
- Crespo‐Garcia, Sergio;
- Pilon, Frédérique;
- Buscarlet, Manuel;
- Beauchemin, Karine;
- Bougie, Véronique;
- Cumberlidge, Garth;
- Wilson, Ariel M;
- Bourgault, Steve;
- Rezende, Flavio A;
- Beaulieu, Normand;
- Delisle, Jean‐Sébastien;
- Sapieha, Przemyslaw
Publication type:
Article

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