Works matching IS 1756994X AND DT 2024 AND VI 16 AND IP 1

Results: 152
    1

    Mitoferrin2 is a synthetic lethal target for chromosome 8p deleted cancers.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01357-w
    By:
    • Krieg, Stephan;
    • Rohde, Thomas;
    • Rausch, Tobias;
    • Butthof, Luise;
    • Wendler-Link, Lena;
    • Eckert, Christoph;
    • Breuhahn, Kai;
    • Galy, Bruno;
    • Korbel, Jan;
    • Billmann, Maximilian;
    • Breinig, Marco;
    • Tschaharganeh, Darjus F.
    Publication type:
    Article
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    Longitudinal analysis within one hospital in sub-Saharan Africa over 20 years reveals repeated replacements of dominant clones of Klebsiella pneumoniae and stresses the importance to include temporal patterns for vaccine design considerations.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01342-3
    By:
    • Heinz, Eva;
    • Pearse, Oliver;
    • Zuza, Allan;
    • Bilima, Sithembile;
    • Msefula, Chisomo;
    • Musicha, Patrick;
    • Siyabu, Patriciah;
    • Tewesa, Edith;
    • Graf, Fabrice E.;
    • Lester, Rebecca;
    • Lissauer, Samantha;
    • Cornick, Jennifer;
    • Lewis, Joseph M.;
    • Kawaza, Kondwani;
    • Thomson, Nicholas R.;
    • Feasey, Nicholas A.
    Publication type:
    Article
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    Knockout mice with pituitary malformations help identify human cases of hypopituitarism.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01347-y
    By:
    • Martinez-Mayer, Julian;
    • Brinkmeier, Michelle L.;
    • O'Connell, Sean P.;
    • Ukagwu, Arnold;
    • Marti, Marcelo A.;
    • Miras, Mirta;
    • Forclaz, Maria V.;
    • Benzrihen, Maria G.;
    • Cheung, Leonard Y. M.;
    • Camper, Sally A.;
    • Ellsworth, Buffy S.;
    • Raetzman, Lori T.;
    • Pérez-Millán, Maria I.;
    • Davis, Shannon W.
    Publication type:
    Article
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    Analysis of 3760 hematologic malignancies reveals rare transcriptomic aberrations of driver genes.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01331-6
    By:
    • Cao, Xueqi;
    • Huber, Sandra;
    • Ahari, Ata Jadid;
    • Traube, Franziska R.;
    • Seifert, Marc;
    • Oakes, Christopher C.;
    • Secheyko, Polina;
    • Vilov, Sergey;
    • Scheller, Ines F.;
    • Wagner, Nils;
    • Yépez, Vicente A.;
    • Blombery, Piers;
    • Haferlach, Torsten;
    • Heinig, Matthias;
    • Wachutka, Leonhard;
    • Hutter, Stephan;
    • Gagneur, Julien
    Publication type:
    Article
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    Variant-specific pathophysiological mechanisms of AFF3 differently influence transcriptome profiles.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01339-y
    By:
    • Bassani, Sissy;
    • Chrast, Jacqueline;
    • Ambrosini, Giovanna;
    • Voisin, Norine;
    • Schütz, Frédéric;
    • Brusco, Alfredo;
    • Sirchia, Fabio;
    • Turban, Lydia;
    • Schubert, Susanna;
    • Abou Jamra, Rami;
    • Schlump, Jan-Ulrich;
    • DeMille, Desiree;
    • Bayrak-Toydemir, Pinar;
    • Nelson, Gary Rex;
    • Wong, Kristen Nicole;
    • Duncan, Laura;
    • Mosera, Mackenzie;
    • Gilissen, Christian;
    • Vissers, Lisenka E. L. M.;
    • Pfundt, Rolph
    Publication type:
    Article
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    INSaFLU-TELEVIR: an open web-based bioinformatics suite for viral metagenomic detection and routine genomic surveillance.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01334-3
    By:
    • Santos, João Dourado;
    • Sobral, Daniel;
    • Pinheiro, Miguel;
    • Isidro, Joana;
    • Bogaardt, Carlijn;
    • Pinto, Miguel;
    • Eusébio, Rodrigo;
    • Santos, André;
    • Mamede, Rafael;
    • Horton, Daniel L.;
    • Gomes, João Paulo;
    • Bigarré, Laurent;
    • Fernández-Pinero, Jovita;
    • Pais, Ricardo J.;
    • Marcacci, Maurilia;
    • Moreno, Ana;
    • Lilja, Tobias;
    • Øines, Øivind;
    • Rzeżutka, Artur;
    • Mathijs, Elisabeth
    Publication type:
    Article
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    Single-cell transcriptomics reveal distinct immune-infiltrating phenotypes and macrophage–tumor interaction axes among different lineages of pituitary neuroendocrine tumors.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01325-4
    By:
    • Lin, Shaojian;
    • Dai, Yuting;
    • Han, Changxi;
    • Han, Tianyi;
    • Zhao, Linfeng;
    • Wu, Renyan;
    • Liu, Jianyue;
    • Zhang, Bo;
    • Huang, Ning;
    • Liu, Yanting;
    • Lai, Shujing;
    • Shi, Jintong;
    • Wang, Yu;
    • Lou, Meiqing;
    • Xie, Jing;
    • Cheng, Yijun;
    • Tang, Hao;
    • Yao, Hong;
    • Fang, Hai;
    • Zhang, Yan
    Publication type:
    Article
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    Metabolic and inflammatory perturbation of diabetes associated gut dysbiosis in people living with and without HIV infection.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01336-1
    By:
    • Luo, Kai;
    • Peters, Brandilyn A.;
    • Moon, Jee-Young;
    • Xue, Xiaonan;
    • Wang, Zheng;
    • Usyk, Mykhaylo;
    • Hanna, David B.;
    • Landay, Alan L.;
    • Schneider, Michael F.;
    • Gustafson, Deborah;
    • Weber, Kathleen M.;
    • French, Audrey;
    • Sharma, Anjali;
    • Anastos, Kathryn;
    • Wang, Tao;
    • Brown, Todd;
    • Clish, Clary B.;
    • Kaplan, Robert C.;
    • Knight, Rob;
    • Burk, Robert D.
    Publication type:
    Article
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    The emergence of highly resistant and hypervirulent Klebsiella pneumoniae CC14 clone in a tertiary hospital over 8 years.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01332-5
    By:
    • Hala, Sharif;
    • Malaikah, Mohammed;
    • Huang, Jiayi;
    • Bahitham, Wesam;
    • Fallatah, Omniya;
    • Zakri, Samer;
    • Antony, Chakkiath Paul;
    • Alshehri, Mohammed;
    • Ghazzali, Raeece Naeem;
    • Ben-Rached, Fathia;
    • Alsahafi, Abdullah;
    • Alsaedi, Asim;
    • AlAhmadi, Ghadeer;
    • Kaaki, Mai;
    • Alazmi, Meshari;
    • AlhajHussein, Baraa;
    • Yaseen, Muhammad;
    • Zowawi, Hosam M.;
    • Alghoribi, Majed F.;
    • Althaqafi, Abdulhakeem O.
    Publication type:
    Article
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    Systematic immune cell dysregulation and molecular subtypes revealed by single-cell RNA-seq of subjects with type 1 diabetes.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01300-z
    By:
    • Honardoost, Mohammad Amin;
    • Adinatha, Andreas;
    • Schmidt, Florian;
    • Ranjan, Bobby;
    • Ghaeidamini, Maryam;
    • Arul Rayan, Nirmala;
    • Gek Liang Lim, Michelle;
    • Joanito, Ignasius;
    • Xiao Xuan Lin, Quy;
    • Rajagopalan, Deepa;
    • Qi Mok, Shi;
    • Hwang, You Yi;
    • Larbi, Anis;
    • Khor, Chiea Chuen;
    • Foo, Roger;
    • Boehm, Bernhard Otto;
    • Prabhakar, Shyam
    Publication type:
    Article
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    NODAL variants are associated with a continuum of laterality defects from simple D-transposition of the great arteries to heterotaxy.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01312-9
    By:
    • Dardas, Zain;
    • Fatih, Jawid M.;
    • Jolly, Angad;
    • Dawood, Moez;
    • Du, Haowei;
    • Grochowski, Christopher M.;
    • Jones, Edward G.;
    • Jhangiani, Shalini N.;
    • Wehrens, Xander H. T.;
    • Liu, Pengfei;
    • Bi, Weimin;
    • Boerwinkle, Eric;
    • Posey, Jennifer E.;
    • Muzny, Donna M.;
    • Gibbs, Richard A.;
    • Lupski, James R.;
    • Coban-Akdemir, Zeynep;
    • Morris, Shaine A.
    Publication type:
    Article
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    Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01321-8
    By:
    • Yabo, Yahaya A.;
    • Moreno-Sanchez, Pilar M.;
    • Pires-Afonso, Yolanda;
    • Kaoma, Tony;
    • Nosirov, Bakhtiyor;
    • Scafidi, Andrea;
    • Ermini, Luca;
    • Lipsa, Anuja;
    • Oudin, Anaïs;
    • Kyriakis, Dimitrios;
    • Grzyb, Kamil;
    • Poovathingal, Suresh K.;
    • Poli, Aurélie;
    • Muller, Arnaud;
    • Toth, Reka;
    • Klink, Barbara;
    • Berchem, Guy;
    • Berthold, Christophe;
    • Hertel, Frank;
    • Mittelbronn, Michel
    Publication type:
    Article
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    scDrugPrio: a framework for the analysis of single-cell transcriptomics to address multiple problems in precision medicine in immune-mediated inflammatory diseases.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01314-7
    By:
    • Schäfer, Samuel;
    • Smelik, Martin;
    • Sysoev, Oleg;
    • Zhao, Yelin;
    • Eklund, Desiré;
    • Lilja, Sandra;
    • Gustafsson, Mika;
    • Heyn, Holger;
    • Julia, Antonio;
    • Kovács, István A.;
    • Loscalzo, Joseph;
    • Marsal, Sara;
    • Zhang, Huan;
    • Li, Xinxiu;
    • Gawel, Danuta;
    • Wang, Hui;
    • Benson, Mikael
    Publication type:
    Article
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    Predicting the presence of coronary plaques featuring high-risk characteristics using polygenic risk scores and targeted proteomics in patients with suspected coronary artery disease.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01313-8
    By:
    • Møller, Peter Loof;
    • Rohde, Palle Duun;
    • Dahl, Jonathan Nørtoft;
    • Rasmussen, Laust Dupont;
    • Nissen, Louise;
    • Schmidt, Samuel Emil;
    • McGilligan, Victoria;
    • Gudbjartsson, Daniel F.;
    • Stefansson, Kari;
    • Holm, Hilma;
    • Bentzon, Jacob Fog;
    • Bøttcher, Morten;
    • Winther, Simon;
    • Nyegaard, Mette
    Publication type:
    Article
    44

    Correction: Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-023-01278-0
    By:
    • Matuozzo, Daniela;
    • Talouarn, Estelle;
    • Marchal, Astrid;
    • Zhang, Peng;
    • Manry, Jeremy;
    • Seeleuthner, Yoann;
    • Zhang, Yu;
    • Bolze, Alexandre;
    • Chaldebas, Matthieu;
    • Milisavljevic, Baptiste;
    • Gervais, Adrian;
    • Bastard, Paul;
    • Asano, Takaki;
    • Bizien, Lucy;
    • Barzaghi, Federica;
    • Abolhassani, Hassan;
    • Tayoun, Ahmad Abou;
    • Aiuti, Alessandro;
    • Darazam, Ilad Alavi;
    • Allende, Luis M.
    Publication type:
    Article
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    Microbial-derived imidazole propionate links the heart failure-associated microbiome alterations to disease severity.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01296-6
    By:
    • Raju, Sajan C.;
    • Molinaro, Antonio;
    • Awoyemi, Ayodeji;
    • Jørgensen, Silje F.;
    • Braadland, Peder R.;
    • Nendl, Andraz;
    • Seljeflot, Ingebjørg;
    • Ueland, Per M.;
    • McCann, Adrian;
    • Aukrust, Pål;
    • Vestad, Beate;
    • Mayerhofer, Cristiane;
    • Broch, Kaspar;
    • Gullestad, Lars;
    • Lappegård, Knut T.;
    • Halvorsen, Bente;
    • Kristiansen, Karsten;
    • Hov, Johannes R.;
    • Trøseid, Marius
    Publication type:
    Article
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    Impact of individual level uncertainty of lung cancer polygenic risk score (PRS) on risk stratification.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01298-4
    By:
    • Wang, Xinan;
    • Zhang, Ziwei;
    • Ding, Yi;
    • Chen, Tony;
    • Mucci, Lorelei;
    • Albanes, Demetrios;
    • Landi, Maria Teresa;
    • Caporaso, Neil E.;
    • Lam, Stephen;
    • Tardon, Adonina;
    • Chen, Chu;
    • Bojesen, Stig E.;
    • Johansson, Mattias;
    • Risch, Angela;
    • Bickeböller, Heike;
    • Wichmann, H-Erich;
    • Rennert, Gadi;
    • Arnold, Susanne;
    • Brennan, Paul;
    • McKay, James D.
    Publication type:
    Article
    49

    Implementation of type 1 diabetes genetic risk screening in children in diverse communities: the Virginia PrIMeD project.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01305-8
    By:
    • Guertin, Kristin A.;
    • Repaske, David R.;
    • Taylor, Julia F.;
    • Williams, Eli S.;
    • Onengut-Gumuscu, Suna;
    • Chen, Wei-Min;
    • Boggs, Sarah R.;
    • Yu, Liping;
    • Allen, Luke;
    • Botteon, Lacey;
    • Daniel, Louis;
    • Keating, Katherine G.;
    • Labergerie, Mika K.;
    • Lienhart, Tyler S.;
    • Gonzalez-Mejia, Jorge A.;
    • Starnowski, Matt J.;
    • Rich, Stephen S.
    Publication type:
    Article
    50

    Genome sequencing as a generic diagnostic strategy for rare disease.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01301-y
    By:
    • Schobers, Gaby;
    • Derks, Ronny;
    • den Ouden, Amber;
    • Swinkels, Hilde;
    • van Reeuwijk, Jeroen;
    • Bosgoed, Ermanno;
    • Lugtenberg, Dorien;
    • Sun, Su Ming;
    • Corominas Galbany, Jordi;
    • Weiss, Marjan;
    • Blok, Marinus J.;
    • Olde Keizer, Richelle A. C. M.;
    • Hofste, Tom;
    • Hellebrekers, Debby;
    • de Leeuw, Nicole;
    • Stegmann, Alexander;
    • Kamsteeg, Erik-Jan;
    • Paulussen, Aimee D. C.;
    • Ligtenberg, Marjolijn J. L.;
    • Bradley, Xiangqun Zheng
    Publication type:
    Article