Works matching IS 1756994X AND DT 2024 AND VI 16 AND IP 1

Results: 152
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    Spatial intra-tumour heterogeneity and treatment-induced genomic evolution in oesophageal adenocarcinoma: implications for prognosis and therapy.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01362-z
    By:
    • Brosda, Sandra;
    • Aoude, Lauren G.;
    • Bonazzi, Vanessa F.;
    • Patel, Kalpana;
    • Lonie, James M.;
    • Belle, Clemence J.;
    • Newell, Felicity;
    • Koufariotis, Lambros T.;
    • Addala, Venkateswar;
    • Naeini, Marjan M.;
    • AGITG DOCTOR Investigators;
    • Simes, John;
    • Walpole, Euan T.;
    • Mai, Gang T.;
    • Watson, David I.;
    • Karapetis, Chris S.;
    • Gebski, Val;
    • Barnes, Elizabeth H.;
    • Oostendorp, Martijn;
    • Wilson, Kate
    Publication type:
    Article
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    SARS-CoV-2 population dynamics in immunocompetent individuals in a closed transmission chain shows genomic diversity over the course of infection.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01360-1
    By:
    • Goldswain, Hannah;
    • Penrice-Randal, Rebekah;
    • Donovan-Banfield, I'ah;
    • Duffy, Craig W.;
    • Dong, Xiaofeng;
    • Randle, Nadine;
    • Ryan, Yan;
    • Rzeszutek, Aleksandra M.;
    • Pilgrim, Jack;
    • Keyser, Emma;
    • Weller, Simon A.;
    • Hutley, Emma J.;
    • Hartley, Catherine;
    • Prince, Tessa;
    • Darby, Alistair C.;
    • Aye Maung, Niall;
    • Nwume, Henry;
    • Hiscox, Julian A.;
    • Emmett, Stevan R.
    Publication type:
    Article
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    Genetic constraint at single amino acid resolution in protein domains improves missense variant prioritisation and gene discovery.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01358-9
    By:
    • Zhang, Xiaolei;
    • Theotokis, Pantazis I.;
    • Li, Nicholas;
    • Ashley, Euan;
    • Colan, Steven D.;
    • Day, Sharlene M.;
    • Helms, Adam;
    • Ho, Carolyn Y.;
    • Ingles, Jodie;
    • Jacoby, Daniel;
    • Lakdawala, Neal K.;
    • Michels, Michelle;
    • Olivotto, Iacopo;
    • Owens, Anjali;
    • Parikh, Victoria N.;
    • Pereira, Alexandre C.;
    • Rossano, Joseph;
    • Saberi, Sara;
    • Semsarian, Chris;
    • Wittekind, Samuel
    Publication type:
    Article
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    Clinical and genomic features of Mycobacterium avium complex: a multi-national European study.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01359-8
    By:
    • Wetzstein, Nils;
    • Diricks, Margo;
    • Anton, Thomas B.;
    • Andres, Sönke;
    • Kuhns, Martin;
    • Kohl, Thomas A.;
    • Schwarz, Carsten;
    • Lewin, Astrid;
    • Kehrmann, Jan;
    • Kahl, Barbara C.;
    • Schmidt, Annika;
    • Zimmermann, Stefan;
    • Jansson, Moritz K.;
    • Baron, Sophie A.;
    • Schulthess, Bettina;
    • Hogardt, Michael;
    • Friesen, Inna;
    • Niemann, Stefan;
    • Wichelhaus, Thomas A.
    Publication type:
    Article
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    PARP4 interacts with hnRNPM to regulate splicing during lung cancer progression.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01328-1
    By:
    • Lee, Yi Fei;
    • Phua, Cheryl Zi Jin;
    • Yuan, Ju;
    • Zhang, Bin;
    • Lee, May Yin;
    • Kannan, Srinivasaraghavan;
    • Chiu, Yui Hei Jasper;
    • Koh, Casslynn Wei Qian;
    • Yap, Choon Kong;
    • Lim, Edwin Kok Hao;
    • Chen, Jianbin;
    • Lim, Yuhua;
    • Lee, Jane Jia Hui;
    • Skanderup, Anders Jacobsen;
    • Wang, Zhenxun;
    • Zhai, Weiwei;
    • Tan, Nguan Soon;
    • Verma, Chandra S.;
    • Tay, Yvonne;
    • Tan, Daniel Shao Weng
    Publication type:
    Article
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    Mitoferrin2 is a synthetic lethal target for chromosome 8p deleted cancers.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01357-w
    By:
    • Krieg, Stephan;
    • Rohde, Thomas;
    • Rausch, Tobias;
    • Butthof, Luise;
    • Wendler-Link, Lena;
    • Eckert, Christoph;
    • Breuhahn, Kai;
    • Galy, Bruno;
    • Korbel, Jan;
    • Billmann, Maximilian;
    • Breinig, Marco;
    • Tschaharganeh, Darjus F.
    Publication type:
    Article
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    Knockout mice with pituitary malformations help identify human cases of hypopituitarism.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01347-y
    By:
    • Martinez-Mayer, Julian;
    • Brinkmeier, Michelle L.;
    • O'Connell, Sean P.;
    • Ukagwu, Arnold;
    • Marti, Marcelo A.;
    • Miras, Mirta;
    • Forclaz, Maria V.;
    • Benzrihen, Maria G.;
    • Cheung, Leonard Y. M.;
    • Camper, Sally A.;
    • Ellsworth, Buffy S.;
    • Raetzman, Lori T.;
    • Pérez-Millán, Maria I.;
    • Davis, Shannon W.
    Publication type:
    Article
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    Variant-specific pathophysiological mechanisms of AFF3 differently influence transcriptome profiles.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01339-y
    By:
    • Bassani, Sissy;
    • Chrast, Jacqueline;
    • Ambrosini, Giovanna;
    • Voisin, Norine;
    • Schütz, Frédéric;
    • Brusco, Alfredo;
    • Sirchia, Fabio;
    • Turban, Lydia;
    • Schubert, Susanna;
    • Abou Jamra, Rami;
    • Schlump, Jan-Ulrich;
    • DeMille, Desiree;
    • Bayrak-Toydemir, Pinar;
    • Nelson, Gary Rex;
    • Wong, Kristen Nicole;
    • Duncan, Laura;
    • Mosera, Mackenzie;
    • Gilissen, Christian;
    • Vissers, Lisenka E. L. M.;
    • Pfundt, Rolph
    Publication type:
    Article
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    Analysis of 3760 hematologic malignancies reveals rare transcriptomic aberrations of driver genes.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01331-6
    By:
    • Cao, Xueqi;
    • Huber, Sandra;
    • Ahari, Ata Jadid;
    • Traube, Franziska R.;
    • Seifert, Marc;
    • Oakes, Christopher C.;
    • Secheyko, Polina;
    • Vilov, Sergey;
    • Scheller, Ines F.;
    • Wagner, Nils;
    • Yépez, Vicente A.;
    • Blombery, Piers;
    • Haferlach, Torsten;
    • Heinig, Matthias;
    • Wachutka, Leonhard;
    • Hutter, Stephan;
    • Gagneur, Julien
    Publication type:
    Article
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    Longitudinal analysis within one hospital in sub-Saharan Africa over 20 years reveals repeated replacements of dominant clones of Klebsiella pneumoniae and stresses the importance to include temporal patterns for vaccine design considerations.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01342-3
    By:
    • Heinz, Eva;
    • Pearse, Oliver;
    • Zuza, Allan;
    • Bilima, Sithembile;
    • Msefula, Chisomo;
    • Musicha, Patrick;
    • Siyabu, Patriciah;
    • Tewesa, Edith;
    • Graf, Fabrice E.;
    • Lester, Rebecca;
    • Lissauer, Samantha;
    • Cornick, Jennifer;
    • Lewis, Joseph M.;
    • Kawaza, Kondwani;
    • Thomson, Nicholas R.;
    • Feasey, Nicholas A.
    Publication type:
    Article
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    INSaFLU-TELEVIR: an open web-based bioinformatics suite for viral metagenomic detection and routine genomic surveillance.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01334-3
    By:
    • Santos, João Dourado;
    • Sobral, Daniel;
    • Pinheiro, Miguel;
    • Isidro, Joana;
    • Bogaardt, Carlijn;
    • Pinto, Miguel;
    • Eusébio, Rodrigo;
    • Santos, André;
    • Mamede, Rafael;
    • Horton, Daniel L.;
    • Gomes, João Paulo;
    • Bigarré, Laurent;
    • Fernández-Pinero, Jovita;
    • Pais, Ricardo J.;
    • Marcacci, Maurilia;
    • Moreno, Ana;
    • Lilja, Tobias;
    • Øines, Øivind;
    • Rzeżutka, Artur;
    • Mathijs, Elisabeth
    Publication type:
    Article
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    Single-cell transcriptomics reveal distinct immune-infiltrating phenotypes and macrophage–tumor interaction axes among different lineages of pituitary neuroendocrine tumors.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01325-4
    By:
    • Lin, Shaojian;
    • Dai, Yuting;
    • Han, Changxi;
    • Han, Tianyi;
    • Zhao, Linfeng;
    • Wu, Renyan;
    • Liu, Jianyue;
    • Zhang, Bo;
    • Huang, Ning;
    • Liu, Yanting;
    • Lai, Shujing;
    • Shi, Jintong;
    • Wang, Yu;
    • Lou, Meiqing;
    • Xie, Jing;
    • Cheng, Yijun;
    • Tang, Hao;
    • Yao, Hong;
    • Fang, Hai;
    • Zhang, Yan
    Publication type:
    Article
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    Metabolic and inflammatory perturbation of diabetes associated gut dysbiosis in people living with and without HIV infection.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01336-1
    By:
    • Luo, Kai;
    • Peters, Brandilyn A.;
    • Moon, Jee-Young;
    • Xue, Xiaonan;
    • Wang, Zheng;
    • Usyk, Mykhaylo;
    • Hanna, David B.;
    • Landay, Alan L.;
    • Schneider, Michael F.;
    • Gustafson, Deborah;
    • Weber, Kathleen M.;
    • French, Audrey;
    • Sharma, Anjali;
    • Anastos, Kathryn;
    • Wang, Tao;
    • Brown, Todd;
    • Clish, Clary B.;
    • Kaplan, Robert C.;
    • Knight, Rob;
    • Burk, Robert D.
    Publication type:
    Article
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    The emergence of highly resistant and hypervirulent Klebsiella pneumoniae CC14 clone in a tertiary hospital over 8 years.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01332-5
    By:
    • Hala, Sharif;
    • Malaikah, Mohammed;
    • Huang, Jiayi;
    • Bahitham, Wesam;
    • Fallatah, Omniya;
    • Zakri, Samer;
    • Antony, Chakkiath Paul;
    • Alshehri, Mohammed;
    • Ghazzali, Raeece Naeem;
    • Ben-Rached, Fathia;
    • Alsahafi, Abdullah;
    • Alsaedi, Asim;
    • AlAhmadi, Ghadeer;
    • Kaaki, Mai;
    • Alazmi, Meshari;
    • AlhajHussein, Baraa;
    • Yaseen, Muhammad;
    • Zowawi, Hosam M.;
    • Alghoribi, Majed F.;
    • Althaqafi, Abdulhakeem O.
    Publication type:
    Article
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    NODAL variants are associated with a continuum of laterality defects from simple D-transposition of the great arteries to heterotaxy.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01312-9
    By:
    • Dardas, Zain;
    • Fatih, Jawid M.;
    • Jolly, Angad;
    • Dawood, Moez;
    • Du, Haowei;
    • Grochowski, Christopher M.;
    • Jones, Edward G.;
    • Jhangiani, Shalini N.;
    • Wehrens, Xander H. T.;
    • Liu, Pengfei;
    • Bi, Weimin;
    • Boerwinkle, Eric;
    • Posey, Jennifer E.;
    • Muzny, Donna M.;
    • Gibbs, Richard A.;
    • Lupski, James R.;
    • Coban-Akdemir, Zeynep;
    • Morris, Shaine A.
    Publication type:
    Article
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    Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01321-8
    By:
    • Yabo, Yahaya A.;
    • Moreno-Sanchez, Pilar M.;
    • Pires-Afonso, Yolanda;
    • Kaoma, Tony;
    • Nosirov, Bakhtiyor;
    • Scafidi, Andrea;
    • Ermini, Luca;
    • Lipsa, Anuja;
    • Oudin, Anaïs;
    • Kyriakis, Dimitrios;
    • Grzyb, Kamil;
    • Poovathingal, Suresh K.;
    • Poli, Aurélie;
    • Muller, Arnaud;
    • Toth, Reka;
    • Klink, Barbara;
    • Berchem, Guy;
    • Berthold, Christophe;
    • Hertel, Frank;
    • Mittelbronn, Michel
    Publication type:
    Article
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    Systematic immune cell dysregulation and molecular subtypes revealed by single-cell RNA-seq of subjects with type 1 diabetes.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01300-z
    By:
    • Honardoost, Mohammad Amin;
    • Adinatha, Andreas;
    • Schmidt, Florian;
    • Ranjan, Bobby;
    • Ghaeidamini, Maryam;
    • Arul Rayan, Nirmala;
    • Gek Liang Lim, Michelle;
    • Joanito, Ignasius;
    • Xiao Xuan Lin, Quy;
    • Rajagopalan, Deepa;
    • Qi Mok, Shi;
    • Hwang, You Yi;
    • Larbi, Anis;
    • Khor, Chiea Chuen;
    • Foo, Roger;
    • Boehm, Bernhard Otto;
    • Prabhakar, Shyam
    Publication type:
    Article
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    scDrugPrio: a framework for the analysis of single-cell transcriptomics to address multiple problems in precision medicine in immune-mediated inflammatory diseases.

    Published in:
    Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01314-7
    By:
    • Schäfer, Samuel;
    • Smelik, Martin;
    • Sysoev, Oleg;
    • Zhao, Yelin;
    • Eklund, Desiré;
    • Lilja, Sandra;
    • Gustafsson, Mika;
    • Heyn, Holger;
    • Julia, Antonio;
    • Kovács, István A.;
    • Loscalzo, Joseph;
    • Marsal, Sara;
    • Zhang, Huan;
    • Li, Xinxiu;
    • Gawel, Danuta;
    • Wang, Hui;
    • Benson, Mikael
    Publication type:
    Article